著者
千葉胤矩 編
出版者
千葉胤矩
巻号頁・発行日
vol.明治27年, 1894
著者
許斐 氏元
出版者
一般社団法人 日本めまい平衡医学会
雑誌
Equilibrium Research (ISSN:03855716)
巻号頁・発行日
vol.76, no.4, pp.286-291, 2017-08-31 (Released:2017-10-01)
参考文献数
40
被引用文献数
1 1
著者
KENJI HASHIMOTO MUNEKI YAMADA YOSHIHITO SHIRAI SHUJI ADACHI
出版者
The Society of Chemical Engineers, Japan
雑誌
JOURNAL OF CHEMICAL ENGINEERING OF JAPAN (ISSN:00219592)
巻号頁・発行日
vol.20, no.4, pp.405-410, 1987-08-20 (Released:2006-04-19)
参考文献数
8
被引用文献数
24 29

Continuous glucose/NaCl separation was successfully performed by using a simulated moving-bed adsorber packed with ion-retardant resin. Two kinds of mathematical models, i.e. an intermittent moving-bed model and a continuous moving-bed model, were proposed to calculate concentration profiles in the adsorber where the adsorption isotherms of the first component (NaCl) and the second component (glucose) are represented respectively by the Langmuir equation and by a linear equation. The validity of the calculation methods proposed was experimentally confirmed.
著者
Takeshi FUJIMURA Aiko IGUCHI Atsushi SATO Shinji KAGAYA Tatsuo HOSHINO Takashi TAKEUCHI
出版者
JAPANESE SOCIETY OF VETERINARY SCIENCE
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
pp.20-0034, (Released:2020-09-25)
被引用文献数
1

Oxaliplatin (OXL) therapy often causes side effects including chronic peripheral neuropathy. We investigated the pain-relieving effects of recombinant human lactoferrin (rhLf) as well as a long-acting IgG-Fc fused rhLf (rhLf-Fc) on OXL-induced neuropathic pain. We used the hLf in this study, because the homology between mouse Lf and hLf is higher than that of bovine Lf. In addition, rhLf-Fc is expected to enhance the analgesic effect due to the life extension effect in the body. We administered OXL (2 mg/kg, i.v.) to mice twice weekly for 4 weeks. Phosphate buffered saline (PBS), rhLf (100 mg/kg, i.p.) or rhLf-Fc (100 mg/kg, i.p.) was administered once a week from day 15 to 32. We also assessed the continuous infusion of same drugs (10 mg/kg/day) into the external jugular vein by using an osmotic pump. Both of rhLf and rhLf-Fc significantly reduced the hypersensitivity to mechanical stimulation when they were administered intraperitoneally. The continuous infusion of rhLf resulted in a more pronounced effect. Histopathological analysis of sciatic nerve showed that both rhLf and rhLf-Fc tended to reduce nerve fiber damage, but no significant difference was observed in nerve fiber cross-sectional area. Therefore, it was suggested that rhLf or rhLf-Fc injection could be an option for controlling neuropathic pain, which are side effects of OXL.
著者
野島 和也 桜庭 雅明
出版者
公益社団法人 土木学会
雑誌
土木学会論文集F3(土木情報学) (ISSN:21856591)
巻号頁・発行日
vol.74, no.2, pp.II_79-II_85, 2018 (Released:2019-03-29)
参考文献数
13

本研究は,土砂氾濫や津波,高潮などの氾濫災害時における氾濫流の来襲状況を把握・体験するための,疑似体験システムを構築するものである.本研究では,汎用的なツールやデータを用いて,容易にVR映像の構築を行うものとした.現実感を高めるため,数値シミュレーションにより氾濫流を再現し,ゲームエンジンを用いてVR映像を作成する仕組みを作成した.氾濫流に流されて来襲する流木や巨石などのがれきは,氾濫発生時の現実感と緊迫感を向上させる要素であり,疑似体験システムにがれきを取り入れる方法を開発した.氾濫流の計算には3次元のVOF法に基づく自由表面流れの計算を汎用CFDコードであるOpenFOAMの自由表面流ソルバを用いるものとし,その結果をゲームエンジンのUnityに取り込む仕組みとした.がれきの挙動の計算は,Unityの物理エンジンを利用し,簡易に実現させる方法を考案した.ヘッドマウントディスプレイ型のバーチャルリアリティ装置を用いて,氾濫流が押し寄せた場合の状況を擬似的に体験できるシステムを構築した.
著者
Fumiaki Beppu Toshiharu Nagai Kazuaki Yoshinaga Hoyo Mizobe Koichi Kojima Naohiro Gotoh
出版者
Japan Oil Chemists' Society
雑誌
Journal of Oleo Science (ISSN:13458957)
巻号頁・発行日
vol.62, no.10, pp.789-794, 2013 (Released:2013-10-02)
参考文献数
33
被引用文献数
3 3

Triacylglycerol (TAG) molecular species were quantified through high-performance liquid chromatography (HPLC) equipped with a nano quantity analyte detector (NQAD). TAG standard compounds, i.e., 1,3-dipalmitoyl-2-oleoylglycerol (β-POP), 1-palmitoyl-2-oleoyl-3-stearoyl-rac-glycerol (β-POS), and 1,3-distearoyl-2-oleoylglycerol (β-SOS), and natural cocoa butter were used for analyses. NQAD gave the first order equation passing through the origin for all TAG standard compounds. TAG molecular species in cocoa butter were quantified using the calibration curves and the obtained values were almost the same as the reported ones of conventional cocoa butter. Furthermore, a recovery test was also carried out and the values were almost 100. Therefore, HPLC-NQAD can be successfully used for the quantification of TAG molecular species in natural fats and oils.