著者

Chunqiu LI Shan WEI Donghua GUO Zhihui WANG Yufei GENG Enyu WANG Xiwen ZHAO Mingjun SU Xinyu WANG Dongbo SUN

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.15-0414, (Released:2015-08-07)

被引用文献数

2 25

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Canine kobuviruses (CaKVs) are newly recognized picornaviruses that have been recently detected in dogs in the USA, Italy, UK, the Republic of Korea and Tanzania. To trace the evolution of CaKV strains, a total of 201 fecal samples from rectal swabs of diarrheic dogs, which were obtained from May 2014 to April 2015 in northeast China, were detected by reverse transcription-PCR targeting a partial (504 bp) fragment of the 3D gene. Furthermore, a phylogenetic analysis of the CaKV strains identified in northeast China was conducted based on the partial 3D gene sequence. The results indicated that 36 fecal samples (17.91%, 36/201) were positive for CaKV, in which the co-infection rates of canine coronavirus, canine parvovirus-2 and canine bocavirus were 58.33%, 41.67%, and 11.11%, respectively. Sequence comparison of the partial 3D gene revealed nucleotide homologies of 94.4–100%, 95.6–98.6%, 94.3–97.6%, 94.4–96.3% and 93.3–95.1% within the 36 Chinese CaKV strains, and between the 36 Chinese CaKV strains and four CaKV reference strains from South Korea, Italy, USA and Tanzania, respectively. A phylogenetic tree revealed that the 36 Chinese CaKV strains formed one specific CaKV lineage with CaKVs that have recently been identified in other countries. The 36 Chinese CaKV strains were closely related to CaKV reference strains from Asia and Europe, but differed genetically from CaKV reference strains from North America and Africa. This study provides evidence that CaKVs circulate in diarrhoetic dogs in China and that they exhibit substantial genetic diversity and high co-infection rates with other enteric viruses.

著者

Bandula Kumara WICKRAMASEKARA RAJAPAKSHAGE Janaka Pradeep Kumara ELLEARAEWE GARUHAMILAGE Dona Daphney Niranjala DE SILVA Ashoka DANGOLLA

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.15-0209, (Released:2015-08-03)

被引用文献数

3

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The purpose of this prospective study was to establish the ultrasonographic characteristics of the dimension of the right pancreatic lobe with that of the associated anatomic landmarks in healthy dogs. Ultrasonographic examinations were performed on 25 dogs. The thickness of the right pancreatic lobe was compared with that of mural thickness of duodenum, diameters of duodenum, pancreatic duct, abdominal aorta, portal vein, caudal vena cava, and length and width of the right kidney and right adrenal gland. The correlation between each pancreatic parameter and the dimensions of the anatomical landmarks were assessed using linear regression analysis and Pearson’s correlation coefficient (r) test. Significant, but weak linear correlations were observed between thickness of right pancreatic lobe with that of duodenum mural thickness (r=0.605, R2=0.339, P=0.001); duodenum diameter (r=0.573, R2=0.299, P=0.003); and right adrenal gland length (r=0.508, R2=0.052, P=0.01). There was no significant dimensional relationship with other selected anatomic landmarks. The ratio between the thickness of right pancreatic lobe and the mural thickness of duodenum, diameter of duodenum and length of right adrenal gland were 2.88 ± 0.53, 1.27 ± 0.27, and 0.81 ± 0.15, respectively. Calculating the ratio of thickness of the right pancreatic lobe with the dimension of significantly correlated anatomic landmarks is a useful and simple method for evaluating the size of the right pancreatic lobe in dogs in clinical practice.

著者

板津 裕己

出版者

一般社団法人 日本教育心理学会

雑誌

教育心理学研究 (ISSN:00215015)

巻号頁・発行日

vol.42, no.1, pp.86-94, 1994-03-30 (Released:2013-02-19)

参考文献数

20

被引用文献数

1

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The aim of this study was to investigate the relation between self-acceptance and interpersonal attitude. Self-acceptance was measured with Self Acceptance Scale (SASSV, Itatsu, 1989, 1993), and interpersonal attitude was done with Interperso nal Attitude Inventory (IAI, Kato & Takagi, 1980) and Interpersonal Relations Inventory (IRI, Fukuyama, 1981). Subjects were 391 male university students. Close relationships were found between many subscales and indices of SASSV, and subscales on IAI and IRI. Every subscale and Basic Trait (Secondary Factor) on SASSV had a close relation with different aspect on interpersonal attitude. Subjects who accepted their own self had a friendly attitude toward others. From the results mentioned above, a hypothesis was built up willing that each trait or factor of self-acceptance had a close relation with specific aspect on interpersonal attitude. DBS (Distance Balance Score), which was one of the indices of SASSV, was related to discrepancy sc ores on IRI. This result meant that inner balance of self-acceptance contributed to disparity between self-attitude and attitude for others.

著者

等々力 心太朗 原田 泰

出版者

一般社団法人 日本デザイン学会

雑誌

日本デザイン学会研究発表大会概要集 日本デザイン学会 第57回研究発表大会

巻号頁・発行日

pp.A13, 2010 (Released:2010-06-15)

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この研究は、リアルタイムドキュメンテーション(以下RTD)のスムーズでクオリティの高い活動を目指している。本研究は、特に紙媒体による表現に主眼を置いている。その目的は、リアルタイムペーパー(以下RTP、参加者がその場で持って帰ることのできる新聞)の表現や制作、記録のノウハウを外在化することである。その研究の一環として、RTDのスタッフやファシリテータとのイメージの共有を目指して、これまでにRTDの活動にて作成されたRTPの分類を行った。その結果、以下のパターンがあげられた。 1.グリッド型 2.チャート型 3.コラム単位型 4.レイヤー構造型 5.マップ型

著者

Keisuke Yanagisawa Takashi Ishida Yutaka Akiyama

出版者

一般社団法人 情報処理学会

雑誌

IPSJ Transactions on Bioinformatics (ISSN:18826679)

巻号頁・発行日

vol.8, pp.21-27, 2015 (Released:2015-08-19)

参考文献数

21

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It is necessary to confirm that a new drug can be appropriately cleared from the human body. However, checking the clearance pathway of a drug in the human body requires clinical trials, and therefore requires large cost. Thus, computational methods for drug clearance pathway prediction have been studied. The proposed prediction methods developed previously were based on a supervised learning algorithm, which requires clearance pathway information for all drugs in a training set as input labels. However, these data are often insufficient in its numbers because of the high cost of their acquisition. In this paper, we propose a new drug clearance pathway prediction method based on semi-supervised learning, which can use not only labeled data but also unlabeled data. We evaluated the effectiveness of our method, focusing on the cytochrome P450 2C19 enzyme, which is involved in one of the major clearance pathways.

著者

Nobuaki Yasuo Masakazu Sekijima

出版者

一般社団法人 情報処理学会

雑誌

IPSJ Transactions on Bioinformatics (ISSN:18826679)

巻号頁・発行日

vol.8, pp.9-13, 2015 (Released:2015-07-08)

参考文献数

25

被引用文献数

1

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We developed a new application to quantitatively evaluate the sequence conservation of ligand-binding sites by integrating information pertaining to protein structures, ligand-binding sites, and amino acid sequences. These data are visualized onto protein structures via a Jmol or PyMOL interface. The visualization is very important for structure-based drug design (SBDD). Key features of this application are the visualization of slight differences in specific ligand-binding sites and ConservationScore comparable among ligand-binding sites. Furthermore, we conducted an experiment to visualize the calculation and comparison of the ConservationScore of four viral proteins as well as an experiment to visualize the differences between proteins belonging to the human β adrenergic receptor family. This application is available at http://www.bio.gsic.titech.ac.jp/visco.html.

著者

Osamu KAWANO Takashi SAWABE Noriyuki MISAKI Kazunaga FUKAWA

出版者

(社)日本薬理学会

雑誌

The Japanese Journal of Pharmacology (ISSN:00215198)

巻号頁・発行日

vol.28, no.6, pp.829-835, 1978 (Released:2006-12-19)

参考文献数

9

被引用文献数

4 14

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In our studies with drug combinations, we searched for mixtures which would enhance the effectiveness of the related active substances. Ethenzamide was found to possess a specific suppressive effect on the gastric damage induced by aspirin. Such effect could not be demonstrated in analgesic agents such as salicylamide, bucetin, acetaminophen and phenacetin. The combination of aspirin with ethenzamide had a potentiating effect on analgesic activity and reduced motor incoordination and loss of righting reflex. We calculated the safety margins of various ratios of combinations and concluded that the best was aspirin and ethenzamide at a ratio of 2:3.

著者

Kohei MURAKAMI Tomohiro YONEZAWA Naoaki MATSUKI

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.15-0263, (Released:2015-08-02)

被引用文献数

2 10

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Idiopathic polyarthritis (IPA) is a very common inflammatory arthropathy in the dog. Canine IPA is diagnosed mainly by detecting increased number of leukocytes in the synovial fluid (SF), which is easily influenced by glucocorticoid therapy. We obtained 31 SF samples from 24 IPA dogs prior to (n=19) and/or after (n=12) 1 to 10 weeks of glucocorticoid therapy. The SF total protein concentrations of IPA dogs were significantly higher than those of dogs with non-arthritis diseases (n=34) and healthy controls (n=10). Our data revealed that the SF total protein concentrations are not influenced by several weeks of glucocorticoid therapy. Hence, the SF total protein concentration is applicable as a diagnostic marker of canine IPA even when the patients are receiving glucocorticoid therapy.

著者

Eiichi KAWAKAMI Masanori KOBAYASHI Tatsuya HORI Takeharu KANEDA

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.15-0294, (Released:2015-08-02)

被引用文献数

1 13

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Four dogs with poor semen quality, low seminal plasma superoxide dismutase (SOD) activity and low blood plasma testosterone (T) levels were orally administered one vitamin E tablet containing 50 mg α-tocopheryl acetate per dog daily for 4 weeks. The mean values of semen quality were temporarily improved after the start of vitamin E treatment and the values of 4, and 5 weeks after that were significantly different from those before the treatment (P<0.05–0.001). The mean blood plasma T and seminal plasma SOD activity values slightly increased in the 4 dogs after the treatment. The results of the present study indicate that poor semen quality in dogs with low seminal plasma SOD can be improved by vitamin E treatment.

著者

横山 昌弘 井沢 靖和 兜 秀昭 山中 千代衛

出版者

社団法人 プラズマ・核融合学会

雑誌

核融合研究 (ISSN:04512375)

巻号頁・発行日

vol.16, no.4, pp.261-264, 1966 (Released:2011-03-04)

参考文献数

6

著者

横山 昌弘 井沢 靖和 兜 秀昭 山中 千代衛

出版者

社団法人 プラズマ・核融合学会

雑誌

核融合研究 (ISSN:04512375)

巻号頁・発行日

vol.16, no.6, pp.509-512, 1966 (Released:2011-03-04)

参考文献数

9

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When an intense laser light passes through a plasma, a small fraction of it is scattered by free electrons. Measurements of the intensity and the spectral distribution of the scattered light from the shocked plasma has been used to determine the electron density and the electron temperature behind the reflected shock waves. Rayleigh scattering signal from one atmospheric pressure air was used as.a measure to evaluate the magnitude of Thomson scattering signal from the shocked plasm, In our experiments the electron densities behind the reflected shock wave at initial pressure of Ar 1 mmHg were determined as. about 1016 cm-3, which were in good agreement with a calculated value by shock theory. By assuming a plasma parameter α=0.85, theoretical curve accords very well with the measured spectral distribution of the scattered light. In this case the electron, temperature behind the refledted shock wave at initial pressure of Ar 0.4 mmHg was 23, 000oK.

著者

的場 徹

出版者

一般社団法人 レーザー学会

雑誌

レーザー研究 (ISSN:03870200)

巻号頁・発行日

vol.3, no.3, pp.143-153, 1975-12-31 (Released:2010-02-26)

参考文献数

35

著者

光永 俊郎 福岡 千鶴子 清水 まゆみ

出版者

The Japan Society of Home Economics

雑誌

家政学雑誌 (ISSN:04499069)

巻号頁・発行日

vol.36, no.9, pp.665-669, 1985-09-20 (Released:2010-03-10)

参考文献数

11

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黒大豆のTI活性は, 黒大豆を煮沸させた調味液に浸漬するだけで50%が失活した.この活性は煮豆過程が進むとともに失われ, 最終的にはTI活性はほとんど認められなくなった.調味液中への活性成分の溶出も非常にわずかであった.一方, 黒大豆粗製TIは加熱により失活し, これは塩基性側, 高水分下で, また豆中のTI以外の物質の存在により促進された.煮豆時にもこれらが熱失活を促進すると考えられた.実際には, pHによる影響は若干であり, 豆中のTI以外の物質および水分により, 大部分のTIが熱失活することが推察された.

著者

後藤 匡史 長木 悠太 鈴木 英之進

出版者

一般社団法人 人工知能学会

雑誌

人工知能学会論文誌 (ISSN:13460714)

巻号頁・発行日

vol.16, no.2, pp.193-201, 2001 (Released:2002-02-28)

参考文献数

13

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This paper presents a novel decision-tree induction for a multi-objective data set, i.e. a data set with a multi-dimensional class. Inductive decision-tree learning is one of the frequently-used methods for a single-objective data set, i.e. a data set with a single-dimensional class. However, in a real data analysis, we usually have multiple objectives, and a classifier which explains them simultaneously would be useful. A conventional decision-tree inducer requires transformation of a multi-dimensional class into a singledimensional class, but such a transformation can considerably worsen both accuracy and readability. In order to circumvent this problem we propose a bloomy decision tree which deals with a multi-dimensional class without such transformations. A bloomy decision tree consists of a set of decision nodes each of which splits examples according to their attribute values, and a set of .ower nodes each of which decidesa dimension of the class for examples. A flower node appears not only at the fringe of a tree but also inside a tree. Our pruning is executed during tree construction, and evaluates each dimension of the class based on Cramér’s V. The proposed method has been implemented as D3-B (Decision tree in Bloom), and tested with eleven benchmark data sets in the machine learning community. The experiments showed that D3-B has higher accuracies in nine data sets than C4.5 and tied with it in the other two data sets. In terms of readability, D3-B has a smaller number of decision nodes in all data sets, and thus outperforms C4.5. Moreover, experts in agriculture evaluated bloomy decision trees, each of which is induced from an agricultural data set, and found them appropriate and interesting.

著者

五島 史行 矢部 はる奈 小川 郁

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.102, no.4, pp.315-320, 2009 (Released:2010-12-04)

参考文献数

15

被引用文献数

1 1

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Introduction: Treatments for acute peripheral vertigo have not been well investigated. The most suitable drug for controlling acute vertigo should suppress both vertigo and accompanying nausea. The purpose of this study was to evaluate the effect of four different drugs on acute peripheral vertigo: (A) hydroxyzine hydrochloride (25 mg, i.v.); (B) 0.5% metoclopramide (2 ml, i.v.); (C) sodium bicarbonate (40 ml, i.v.); and (D) a cocktail of diphenhydramine hydrochloride (30 mg) and dyprophylline (26 mg) (both i.m.). Methods: Forty-two patients with acute peripheral vertigo (average age: 59.5±18.1 years) with spontaneous nystagmus were assigned to four treatment groups (A-D, above). Patients with central vertigo and vestibular neuritis were excluded. The number of patients in each group was as follows: A, n=11; B, n=11; C, n=11; and D, n=9. Patients were instructed to evaluate their subjective symptoms of nausea and vertigo before and 30 minutes after drug treatment. They rated the severity of their symptoms on a 0-to-10 scale, with 10 representing the most severe symptoms and 0 a lack of symptoms. Results: Group A patients (hydroxyzine hydrochloride; 25 mg, i.v.) reported the highest level of relief from vertigo and nausea after drug treatment, whereas group C (sodium bicarbonate; 40 ml, i.v.) and D (diphenhydramine hydrochloride (30 mg)-dyprophylline (26 mg) cocktail; i.m.) patients reported only the slight relief of these symptoms. Group B patients (0.5% metoclopramide; 2 ml, i.v.) experienced partial symptom relief; their vertigo remained unchanged. Thus, hydroxyzine hydrochloride (A) was the most effective in controlling both nausea and vertigo, whereas sodium bicarbonate (C) and diphenhydramine hydrochloride and dyprophylline (D) only slightly suppressed vertigo and nausea. Metoclopramide (B) only suppressed nausea. Conclusions: Hydroxyzine hydrochloride (A) was the most suitable for treating acute peripheral vertigo. Doctors should be familiar with the contraindications of these drugs. Some of these drugs may potentially be used in combination to control the symptoms of acute vertigo more effectively.

著者

安本 雅典 許 経明 任 懿君

出版者

特定非営利活動法人 組織学会

雑誌

組織学会大会論文集 (ISSN:21868530)

巻号頁・発行日

vol.4, no.1, pp.89-94, 2015-07-31 (Released:2015-07-31)

参考文献数

16

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The article attempts to elucidate why incumbent leading standard setters lose their grounds through technology spillovers in the surge of standardization. We conduct the analysis of patent forward citations from essential patents (SEP), which are declared linked with standard specifications, to proprietary patents in the telecommunication industry. The results show that by assimilating relevant knowledge from leading standard setters, semiconductor suppliers attempt to build their knowledge mainly related to “interface” between telecommunication systems and mobile phones. The results also reveal that a major semiconductor supplier, Qualcomm, plays as a hub which accelerates the knowledge spillovers from leading standard setters to other semiconductor suppliers. These findings are expected to expand the debates of standard setters' knowledge management and provide managerial implications for practitioners.

著者

梶谷 克彦

出版者

日本感性工学会

雑誌

日本感性工学会論文誌 (ISSN:18840833)

巻号頁・発行日

pp.TJSKE-D-15-00006, (Released:2015-08-11)

参考文献数

15

被引用文献数

1

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In this study, I propose that a local event can be considered as a “system for information transmission”. Such a system has three functions, namely, “information”, “production”, and “acceptability”. This study provides a conceptual diagram for depicting a local event as a system for information transmission. Though local events can be classified in different ways, they are represented using a specific image in the conceptual diagram. Furthermore, in order to understand the current local events, I compare these events to those that occurred during the Japanese bubble economy.

著者

伊能 嘉矩

出版者

日本人類学会

雑誌

東京人類學會雜誌 (ISSN:18847641)

巻号頁・発行日

vol.12, no.133, pp.259-272, 1897-04-28 (Released:2010-06-28)

著者

伊能 嘉矩

出版者

日本人類学会

雑誌

東京人類學會雜誌 (ISSN:18847641)

巻号頁・発行日

vol.12, no.128, pp.35-48, 1896-11-28 (Released:2010-06-28)

著者

伊能 嘉矩

出版者

日本人類学会

雑誌

東京人類學會雜誌 (ISSN:18847641)

巻号頁・発行日

vol.11, no.124, pp.381-389, 1896-07-28 (Released:2010-06-28)