著者

Toshiyuki Iwame Tetsuya Matsuura Naoto Suzue Shinji Kashiwaguchi Takenobu Iwase Shoji Fukuta Daisuke Hamada Tomohiro Goto Takahiko Tsutsui Keizo Wada Hiroshi Egawa Akihiro Nagamachi Koichi Sairyo

出版者

徳島大学医学部

雑誌

The Journal of Medical Investigation (ISSN:13431420)

巻号頁・発行日

vol.63, no.3.4, pp.171-174, 2016 (Released:2016-09-17)

参考文献数

11

被引用文献数

10

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Purpose: Our aim was to examine the outcome of an elbow check-up system for youth baseball players. In particular, we investigated the nature of elbow injuries in youth baseball players with elbow pain and ultrasonographic findings of the capitellum. Materials and Methods: A total of 1605 players participating in the regional summer championship in July 2013 underwent a questionnaire survey, physical examination, ultrasound imaging, and radiographic examination. Results: A total of 499 (31.1%) players reported episodes of elbow pain, of whom 320 (64.1%) had abnormal findings on physical examination, and 115 (35.9%) agreed to undergo radiography. Among them, 98 (85.2%) exhibited radiographic abnormalities. On the initial ultrasonography screening, 60 (3.7%) players had an abnormal finding and 55 (91.7%) agreed to undergo radiography. Among them, 26 (47.3%) were found to have osteochondritis dissecans (OCD) of the capitellum on radiographs. Conclusions: About 30% of youth baseball players had episodes of elbow pain, and 64.1% of players with elbow pain had abnormal findings on physical examination. Furthermore, 85.2% of subjects who underwent radiographic examination exhibited radiographic abnormalities. About 4% of young baseball players had an abnormal finding on initial ultrasonography screening, and nearly 50% of them had OCD of the capitellum on radiographs. J. Med. Invest. 63: 171-174, August, 2016

著者

Kenichiro Yaita Yoshiro Sakai Kenji Masunaga Hiroshi Watanabe

出版者

一般社団法人 日本内科学会

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

vol.55, no.6, pp.605-608, 2016 (Released:2016-03-15)

参考文献数

18

被引用文献数

2 7

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Objective To clarify the current situation concerning drug fever (DF) in Japan, we retrospectively analyzed patients undergoing infectious disease consultation at our institution. Methods Between April 2014 and May 2015, we extracted the records of DF patients from among 388 patients who had obtained infectious disease consultations in Kurume University Hospital. We reviewed their medical charts and summarized the characteristics of DF. Results This study included the records of 16 patients. Clinical signs (relative bradycardia, the duration of the drug administration before becoming febrile, and the interval between the discontinuation of a drug and the alleviation of a fever), and laboratory tests (varied white blood cell count, low level of C-reactive protein, and a mild elevation of transaminases) were compatible with those from previous reports. Among the drug-confirmed cases, five involved the use of glycopeptides (vancomycin: 3, teicoplanin: 2), which were considered to be uncommon causes, and the another five cases involved the use of β-lactams. In addition, the procalcitonin levels were either negative or low (≤0.25 ng/mL) in 10 of the 11 procalcitonin-measured cases. Conclusion Our findings demonstrated that glycopeptides, similar to β-lactams, may be the origin of DF. Furthermore, procalcitonin may be helpful in the diagnosis of DF, but only in combination with other detailed examinations.

著者

Kimiko Tomioka Norio Kurumatani Hiroshi Hosoi

出版者

日本疫学会

雑誌

Journal of Epidemiology (ISSN:09175040)

巻号頁・発行日

vol.26, no.7, pp.361-370, 2016-07-05 (Released:2016-07-05)

参考文献数

58

被引用文献数

3 54

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Background: This study’s aim was to clarify the relationship of having hobbies and a purpose in life (PIL; in Japanese, ikigai) with mortality and a decline in the activities of daily living (ADL) and instrumental ADL (IADL) among the community-dwelling elderly.Methods: Prospective observational data from residents aged ≥65 years who were at increased risk for death (n = 1853) and developing a decline in ADL (n = 1254) and IADL (n = 1162) were analyzed. Cox proportional hazard models were used for mortality analysis of data from February 2011 to November 2014. ADL and IADL were evaluated using the Barthel Index and the Tokyo Metropolitan Institute of Gerontology Index of Competence, respectively. ADL and IADL were assessed at baseline and follow-up and were evaluated using logistic regression models. Fully adjusted models included terms for age, gender, BMI, income, alcohol intake, smoking history, number of chronic diseases, cognitive function, and depression.Results: During the follow-up of eligible participants, 248 had died, 119 saw a decline in ADL, and 178 saw a decline in IADL. In fully adjusted models, having neither hobbies nor PIL was significantly associated with an increased risk of mortality (hazard ratio 2.08; 95% confidence interval [CI], 1.47–2.94), decline in ADL (odds ratio 2.74; 95% CI, 1.44–5.21), and decline in IADL (odds ratio 1.89; 95% CI, 1.01–3.55) compared to having both hobbies and PIL.Conclusions: Although effect modifications by cognitive functioning and depression cannot be ruled out, our findings suggest that having hobbies and PIL may extend not only longevity, but also healthy life expectancy among community-dwelling older adults.

著者

Hiroshi Yoshikura

出版者

国立感染症研究所 Japanese Journal of Infectious Diseases 編集委員会

雑誌

Japanese Journal of Infectious Diseases (ISSN:13446304)

巻号頁・発行日

vol.69, no.3, pp.272-272, 2016 (Released:2016-05-20)

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Volume 69, no. 2, p. 97–108, 2016. Page 107, Figure 11 should appear as shown below.

著者

Takayoshi Yamashita Takaya Nakamura Hiroshi Fukui Yuji Yamauchi Hironobu Fujiyoshi

出版者

一般社団法人 情報処理学会

雑誌

IPSJ Transactions on Computer Vision and Applications (ISSN:18826695)

巻号頁・発行日

vol.7, pp.99-103, 2015 (Released:2015-07-27)

参考文献数

15

被引用文献数

6

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Facial part labeling which is parsing semantic components enables high-level facial image analysis, and contributes greatly to face recognition, expression recognition, animation, and synthesis. In this paper, we propose a cost-alleviative learning method that uses a weighted cost function to improve the performance of certain classes during facial part labeling. As the conventional cost function handles the error in all classes equally, the error in a class with a slightly biased prior probability tends not to be propagated. The weighted cost function enables the training coefficient for each class to be adjusted. In addition, the boundaries of each class may be recognized after fewer iterations, which will improve the performance. In facial part labeling, the recognition performance of the eye class can be significantly improved using cost-alleviative learning.

著者

大竹 正徳 WILLIAM J. SCHULL HIROSHI YOSHIMARU

出版者

Journal of Radiation Research 編集委員会

雑誌

Journal of Radiation Research (ISSN:04493060)

巻号頁・発行日

vol.32, no.SUPPLEMENT, pp.249-264, 1991 (Released:2006-05-31)

参考文献数

33

被引用文献数

23 56

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Significant effects on the developing brain of exposure to ionizing radiation are seen among those individuals exposed in the 8th through the 25th week after fertilization. These effects, particularly in the most sensitive period, 8-15 weeks after fertilization, manifest themselves as an increased frequency of severe mental retardation (SMR), a diminution in IQ score and in school performance, and an increase in the occurrence of seizures. Of 30 SMR cases, 18 (60%) had small heads. About 10% of the individuals with small head sizes observed among the in utero clinical sample were mentally retarded. When all of the cases of mental retardation are included in the analysis, a linear dose-response model fits the data adequately and no evidence of a threshold emerges; however, if the two probable nonradiation-related cases of Down''s syndrome are excluded from the 19 SMR cases exposed 8-15 weeks after fertilization, the evidence of a threshold is stronger. The 95% lower bound of the threshold based on the new dosimetry system appears to be in the range of 0.12-0.23 Gy. In the 16-25 week period, the 95% lower bound of the threshold is 0.21 Gy both with and without inclusion of two probable nonradiationrelated retarded cases. In a regression analysis of IQ scores and school performance data, a greater linearity is suggested with the new dosimetry (DS86) than with the old (T65DR), but the mean IQ score and the mean school performance of those exposed in utero to doses under 0.10 Gy are similar, and not statistically different from the means in the control group. The risk ratios for unprovoked seizures, following exposure during the 8th through the 15th week after fertilization, are 4.4 (90% confidence interval: 0.5-40.9) after 0.10-0.49 Gy and 24.9 (4.1-191.6) after 0.50 Gy or more when the mentally retarded are included and 4.4 (0.5-40.9) and 14.5 (0.4-199.6), respectively, when they are excluded.

著者

Shunsuke Ochiai Atsuya Watanabe Hideshi Oda Hiroshi Ikeda

出版者

理学療法科学学会

雑誌

Journal of Physical Therapy Science (ISSN:09155287)

巻号頁・発行日

vol.26, no.2, pp.281-284, 2014 (Released:2014-02-28)

参考文献数

30

被引用文献数

4 17 1

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[Purpose] Superficial heat treatment is one of the most widely used physical therapies for osteoarthritis (OA). We clinically evaluated the effects of local heat treatment and exercise therapy for knee OA, and evaluated the articular cartilage using magnetic resonance imaging (MRI) T2 mapping. [Subjects and Methods] Eighteen females aged 50–69 (59.5 ± 8.5 years, mean ± SD) years diagnosed with early-stage knee OA were randomly assigned using computer-generated random numbers to either a local heat treatment group (LH group, 9 subjects) or an exercise therapy group (EX group, 9 subjects). These groups were subjected to a 12-week intervention experiment. MRI T2 mapping was performed for cartilage imaging and quantitative evaluation. For clinical evaluation, the Japanese Knee Osteoarthritis Measure (JKOM) and the Timed Up and Go (TUG) test were performed. Both clinical and MRI evaluations were performed at the beginning and end of the intervention (0 week (Time 0) and 12 weeks). [Results] The total JKOM score had a significantly decreased in the LH group at 12 weeks. However, in the EX group the total JKOM scores at Time 0 and 12 weeks were not significantly different. The TUG time in the EX group was significant shorter at 12 weeks, whereas it showed no significant change in the LH group at 12 weeks, though the TUG times of 7 of the 9 patients decreased, exhibiting some improvement. The T2 value of the LH group was significantly shorter at 12 weeks. However, the T2 value in the EX group showed no significant change at 12 weeks. [Conclusion] After local heat treatment using heat- and steam moisture-generating sheets for 12 weeks, we observed improvements in clinical symptoms and walking abilities. Moreover, positive effects on cartilage metabolism were suggested.

著者

Ban Hiroshi Yamamoto Hiroki Hanakawa Takashi Urayama Shin-Ichi Aso Toshihiko Fukuyama Hidenao Ejima Yoshimichi

出版者

The Society for Neuroscience

雑誌

The Journal of neuroscience : the official journal of the Society for Neuroscience (ISSN:02706474)

巻号頁・発行日

vol.33, no.43, pp.16992-17007, 2013-10-23

被引用文献数

35

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モノの背後を見る脳の仕組みを解明 -視対象の部分像から全体像を復元する第1次視覚野の活動をfMRIで観察-. 京都大学プレスリリース. 2013-10-23.

著者

Bei Zhou Hisami Yamanaka-Okumura Sayaka Seki Hiroshi Tatano Chisaki Adachi Eiji Takeda

出版者

徳島大学医学部

雑誌

The Journal of Medical Investigation (ISSN:13431420)

巻号頁・発行日

vol.61, no.1.2, pp.118-125, 2014 (Released:2014-04-04)

参考文献数

25

被引用文献数

1 4

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In general, vegetables are abundantly consumed in a calorie-restricted diet to achieve sufficient satiety through fresh food or various cooking methods. In this study, we examined the effects of different cooking methods on appetite and specific perceptions of the food after consumption; eating approaches were also analyzed by meal duration. A total of 153 individuals aged 20-59 years were assigned to 2 groups: raw vegetable or boiled vegetable meals, including packed meals that were served as test meals with the same energy and vegetable amount. Subjective levels of sensory properties and meal duration were assessed over time using visual analog scales, including questionnaires. Results showed that meal duration was significantly longer for raw vegetable meals than boiled vegetable meals, and there were significantly stronger correlations between meal duration and fullness. A higher degree of fullness was provided by a raw vegetable meal than a boiled vegetable meal, especially in men. However, an excess of raw vegetables led to overall insufficient satisfaction. Taken together, these findings suggest that cooking methods should be altered for different situations with an adequate amount of vegetables, and the meal duration should be recommended to be given as much attention as cooking methods. J. Med. Invest. 61: 118-125, February, 2014

著者

Hiroshi SUNAHARA Yoko FUJII Keisuke SUGIMOTO Takuma AOKI Gou SUGAHARA Kinji SHIROTA

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.14-0242, (Released:2014-09-23)

被引用文献数

3

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A two-month-old female Chihuahua was diagnosed as severe pulmonary valvular stenosis (PS). Although balloon valvuloplasty (BV) was successfully performed, restenosis was observed 19 months after the procedure. Euthanasia was chosen due to low output syndrome during the surgical repair attempted when the dog was 5 years old. Postmortem examination revealed markedly thickened pulmonary valve due to the increase of extracellular matrix which might be produced by increased α smooth muscle actin-positive myofibroblasts. The thickening of the valve was associated with restriction of the valve’s motion, resulting in restenosis in the present case. This is the first case report documented histopathological and immunohistochemical findings of the restenotic pulmonary valve in dogs with PS after BV.

著者

Takao Sato Tomoki Kameyama Takashi Ohori Akira Matsuki Hiroshi Inoue

出版者

一般社団法人 日本動脈硬化学会

雑誌

Journal of Atherosclerosis and Thrombosis (ISSN:13403478)

巻号頁・発行日

pp.23390, (Released:2014-05-16)

参考文献数

53

被引用文献数

1 15

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Aim: Epicardial adipose tissue (EAT) is a pathogenic fat depot that may be associated with coronary atherosclerosis and cardiovascular events. Because eicosapentaenoic acid (EPA) has been reported to exert cardiovascular protective effects, we aimed to assess the effects of EPA on the volume of visceral adipose tissue, including EAT and abdominal visceral adipose tissue (AVAT), using multislice computed tomography (CT). Methods: In 30 patients with coronary artery diseases (9 women; mean age, 67.2±5.4 years), EAT and AVAT volumes were compared between the control group (n=15, conventional therapy) and the EPA group (n=15, conventional therapy plus purified EPA 1800 mg/day) during a six-month period. EAT was defined as any pixel that had CT attenuation of -150 to -30 Hounsfield units (HU) within the pericardial sac. Results: After the six-month follow-up, the serum EPA level increased from 59.9±18.8 to 177.2± 3.3 μg/mL in the EPA group (p<0.01), but no increase was noted in the control group. Similarly, the EPA/arachidonic acid (AA) ratio increased from 0.39±0.12 to 1.22±0.28 in the EPA group (p<0.01), with no significant increase in the control group. The AVAT and EAT volumes decreased in the EPA group but were unchanged in the control group (AVAT, −11.6±17.0 vs. +8.8±13.6 cm2, p<0.01; EAT, −7.3±8.3 vs. +8.7±8.8 cm3, p<0.01). Moreover, the change in the AVAT volume negatively correlated with the change in EPA (r=−0.58, p<0.01) and EPA/AA levels (r=−0.53, p<0.01). A similar negative correlation in these parameters was also observed for the EAT volume. Conclusions: Oral intake of purified EPA appears to be associated with reductions in EAT and AVAT volumes.

著者

松野 渉 本田 咲美 池内 有為 佐藤 翔 逸村 裕 Matsuno Wataru Itsumura Hiroshi

出版者

日本図書館情報学会

巻号頁・発行日

2012

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2012年日本図書館情報学会春季研究集会. 三重大学, 2012-05-12

著者

Kentaro Araki Hiroshi Ishimoto Masataka Murakami Takuya Tajiri

出版者

(公社)日本気象学会

雑誌

SOLA (ISSN:13496476)

巻号頁・発行日

vol.10, pp.57-61, 2014 (Released:2014-04-24)

参考文献数

20

被引用文献数

1 3

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We examined proximity soundings at intervals of a few minutes and at distances of less than 20 km from a significant tornadic (SIGTOR) supercell that occurred on 6 May 2012 in Japan. We used a 1-dimensional variational (1DVAR) technique that combined the observations of a ground-based microwave radiometer with outputs from a numerical model. Based on the results of the 1DVAR, several supercell and tornado forecast parameters were calculated and compared with values typical of SIGTOR supercell environments in the United States. One and a half hours before the occurrence of the tornado, the value of convective available potential energy increased significantly to about 1000 J kg−1, a value that is smaller than the typical value in the United States. Low-level vertical wind shear and some composite parameters attained maximum values at the time when the distance to the supercell was the smallest. The vertical wind shear parameters and some composite parameters indicated that the environment fell into the SIGTOR supercell category. This result shows that the thermodynamic environments became unstable before the approach of the supercell, and the low-level vertical wind shear changed locally near the supercell.

著者

豊田 弘司 森田 泰介 岡村 季光 イナモリ リョウコ 豊田 弘司 森田 泰介 岡村 季光 稲森 涼子 TOYOTA Hiroshi MORITA Taisuke OKAMURA Toshimitsu INAMORI Ryoko

出版者

奈良教育大学教育学部附属教育実践総合センター

雑誌

教育実践総合センター研究紀要 (ISSN:13476971)

巻号頁・発行日

no.17, pp.29-34, 2008-03

著者

森田 裕司 Morita Hiroshi モリタ ヒロシ

出版者

広島経済大学経済学会

雑誌

広島経済大学研究論集 (ISSN:03871444)

巻号頁・発行日

vol.26, no.1, pp.83-87, 2003-06

著者

大村 英昭 塩原 勉 厚東 洋輔 山中 浩司 Eishou Ohmura Tsutomu Shiobara Yosuke Koto Hiroshi Yamanaka

雑誌

社会学部紀要 (ISSN:04529456)

巻号頁・発行日

no.112, pp.29-35, 2011-03-15

著者

Toyotaka SATO Shin-ichi YOKOTA Torahiko OKUBO Kanako ISHIHARA Hiroshi UENO Yasukazu MURAMATSU Nobuhiro FUJII Yutaka TAMURA

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.12-0186, (Released:2012-11-14)

被引用文献数

8 30

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Fluoroquinolone resistance is mainly caused by mutations in quinolone resistance-determining regions of DNA gyrase and topoisomerase IV in Escherichia coli. The AcrAB-TolC efflux pump contributes to resistance against fluoroquinolone and other antimicrobials. In this study, we investigated a high-level mechanism of fluoroquinolone resistance in E. coli that was isolated from human clinical samples and canine fecal samples. E. coli strains with high levels of fluoroquinolone resistance have been found to be frequently resistant to cephalosporins. Strains with high-level fluoroquinolone resistance exhibited lower intracellular enrofloxacin (ENR) concentrations, higher expression of AcrA, and a greater reduction in the fluoroquinolone minimum inhibitory concentration for treatment with an efflux pump inhibitor. The frequency of strains with enhanced ENR resistance selection and the survival rate of E. coli in the presence of ENR in vitro were correlated well with AcrA protein expression levels in the parental strains. These results suggest that AcrAB-TolC efflux pump over-expression is related to high-level fluoroquinolone resistance and the selection of strains with enhanced fluoroquinolone resistance.

著者

Imamichi Takashi Yagiura Mutsunori Nagamochi Hiroshi

出版者

Elsevier

雑誌

Discrete Optimization (ISSN:15725286)

巻号頁・発行日

vol.6, no.4, pp.345-361, 2009-11

被引用文献数

70

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The irregular strip packing problem is a combinatorial optimization problem that requires to place a given set of two-dimensional polygons within a rectangular container so that no polygon overlaps with other polygons or protrudes from the container, where each polygon is not necessarily convex. The container has a fixed width, while its length can change so that all polygons are placed in it. The objective is to find a layout of the set of polygons that minimizes the length of the container. We propose an algorithm that separates overlapping polygons based on nonlinear programming, and an algorithm that swaps two polygons in a layout so as to find their new positions in the layout with the least overlap. We incorporate these algorithms as components into an iterated local search algorithm for the overlap minimization problem and then develop an algorithm for the irregular strip packing problem using the iterated local search algorithm. Computational comparisons on representative instances disclose that our algorithm is competitive with other existing algorithms. Moreover, our algorithm updates several best known results.

著者

種市 淳子 逸村 裕 TANEICHI Junko ITSUMURA Hiroshi

出版者

名古屋大学附属図書館研究開発室

雑誌

名古屋大学附属図書館研究年報 (ISSN:1348687X)

巻号頁・発行日

vol.5, pp.57-68, 2007-03-31 (Released:2009-02-10)

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Using an OPAC (Online Public Access Catalog) that provides search access points with a table of contents at a college library, we implemented analysis of OPAC access logs and a search experiment. We examined information seeking behaviors by taking advantage of OPAC. We conducted the analysis by paying particular attention to the effects on seeking behaviors of differences in experience in using search engines. As a result of our research, three things have become clear. 1) It is typical that the students combine one or two words to make a search term and they have a tendency to use free terms frequently. 2) In more than half of the search results, the search terms were found in the tables of contents. 3) Experiences of using search engines affected how to deal with the situation when a search receives no hits. The students are rarely conscious of the difference between searches by OPACs and search engines. These results indicate that a search system based on standard bibliographic information in traditional OPAC cannot respond to users’various information seeking behaviors.

著者

Tamaki Sato Kazuhiro Tobiishi Tsuguhide Hori Tomoaki Tsutsumi Hiroshi Akiyama Toshiro Matsui

出版者

Japanese Society for Food Science and Technology

雑誌

Food Science and Technology Research (ISSN:13446606)

巻号頁・発行日

vol.29, no.4, pp.347-356, 2023 (Released:2023-07-20)

参考文献数

39

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We investigated the concentrations of halogenated flame retardants (HFRs), which include hexabromocyclododecanes (HBCDDs), polybrominated diphenyl ethers (PBDEs), and dechloranes and related compounds (DRCs), in 25 typical ready-made boxed sushi meals (each divided into seafood and non-seafood portions) using a developed simultaneous analytical method involving accelerated solvent extraction and gel permeation chromatographic separation. The developed method yielded good recoveries of surrogates (72–122 %). HBCDDs, PBDEs, and DRCs were detected in all seafood portions. While DRCs were also frequently detected in non-seafood portions, HBCDDs and PBDEs were hardly detected. The estimated dietary intakes of HBCDDs, PBDEs, and DRCs from boxed sushi meals were well below the corresponding health-based guideline values. In conclusion, our study suggests that the intake of HFRs from boxed sushi meals poses low concern for consumer health and that the developed simultaneous analytical method is highly useful for determining HFRs in seafood-based meals.