著者
イングリッド・S・ スノロ 細野 明義
出版者
日本酪農科学会
雑誌
酪農科学・食品の研究 (ISSN:03850218)
巻号頁・発行日
vol.44, no.3, pp.A-91-A-98, 1995 (Released:2015-10-31)
参考文献数
20

インドネシアは世界最大の群島であり,多くの伝統的発酵食品が存在する。それら発酵食品には微生物としてカビ,酵母,細菌が関与しているが,構成微生物菌叢や製造過程での成分変化について明らかにされているものは極く一部に過ぎない。本稿ではカビを用いて製造するオンチョム,テンペ,タウチョ, ケチャップ,酵母を用いて製造するタペシンコン,タペクタン,ブルムケーキ,ブルムバリ,そして細菌を用いて製造するダディヒ,ミニャクサミン,テラシ,ケチャップイカン,イカンペダ,テルルアシン,テムポヤについて新しい知見と併せ紹介する。
著者
Kazuya YOSHIDA S.L. IRISHI J. A. BOOSE
出版者
Parenteral Drug Association Japan Chapter
雑誌
日本PDA学術誌 GMPとバリデーション (ISSN:13444891)
巻号頁・発行日
vol.1, no.2, pp.71-76, 1999 (Released:2006-08-03)
参考文献数
7

Viral spiking studies were used to validate the capacity of our manufacturing process of a biological product derived from animal origin to inactivate or eliminate potential viral contaminants. Since the present study was intended for early Phase I & II clinical trials, two model viruses, Xenotropic Murine Leukemia Virus and polio virus, type 1, which represent a range of physical, chemical, and biological properties were selected for examination. It is generally recommended to take at least two different viral inactivation removed procedures for the robustness of the manufacturing process. We therefore selected a heat treatment and an ethanol purification step, two steps which held the potential for inactivation through independent mechanisms (i.e., physical and chemical inactivation, respectively). Finally, with the design of the experiment taken into consideration, the manufacturing steps were scaled-down and validated. Further, based upon the data collected during validation, the step parameters used for the present study were considered worst-cases. The result of the present spiking study for the two steps was a combined reduction of > 11 logs for polio virus and > 8 logs for X-MuLV which was the maximum attainable clearance given the spiking titer and dilution level for both viruses and both manufacturing steps.
著者
佐野 武仁 内田 敦子 Takehito SANO Atsuko UCHIDA 昭和女子大学生活環境学科 昭和女子大学生活環境学科 Department of Human Environmental Science and Design Showa Women's University Department of Human Environmental Science and Design Showa Women's University
出版者
昭和女子大学近代文化研究所
雑誌
學苑 = GAKUEN (ISSN:13480103)
巻号頁・発行日
vol.813, pp.49-57, 2008-07-01

There are various theories about the origin of glass. One is that glass beads were made during the time of the Old Kingdom in Egypt (27th-22nd century BC). Another suggests that glass was first manufactured around 18th-17th century BC. The truth is uncertain. Without a doubt, however, glass has been a notable feature of a great deal of architecture, most notably the Crystal Palace which was built on the grounds of the first World Exposition, held in Hyde Park, London, in 1851. It was an enormous building made from an iron frame work and glass. The theme of this paper is the continuing evolution of glass architecture. It discusses design, and plans which make full use of state-of-the-art technology to achieve energy conservation. Here, the term "glass architecture" refers to buildings whose outer walls and roofs are mainly or entirely made of glass. The distinguishing features of glass architecture can be described as follows: (1) In glass architecture, the aim is to bring more light into the building, and thereby create building with a healthy environment and outstanding occupant comfort, which prevents people from getting sick. This can be achieved by skillfully using natural conditions such as light and heat. (2) Transparent architecture allows people to see the sunny sky on clear days, and the cloudy sky when it is overcast. Sunshades are indispensable fixtures which enable adjustment of light and heat. (3) Glass architecture is the starting point for greenhouses, and the standard practice is to investigate greenhouses first when looking at design and functions such as ventilation or the heat/light environment. (4) If intelligent design and function are built in, then it is possible to construct glass architecture with outstanding occupant comfort, and low overhead thanks to energy conservation. (5) Since there are too many types of glass, and this makes things difficult to understand, a classification is used which combines the glass manufacturing process and sunshades.
著者
Elhussein F Mourad Mohamed S Sarhan Hassan-Sibroe A Daanaa Mennatullah Abdou Ahmed T Morsi Mohamed R Abdelfadeel Hend Elsawey Rahma Nemr Mahmoud El-Tahan Mervat A Hamza Mohamed Abbas Hanan H Youssef Abdelhadi A Abdelhadi Wafaa M Amer Mohamed Fayez Silke Ruppel Nabil A Hegazi
出版者
日本微生物生態学会・日本土壌微生物学会
雑誌
Microbes and Environments (ISSN:13426311)
巻号頁・発行日
pp.ME17135, (Released:2018-02-23)
被引用文献数
22

In order to improve the culturability and biomass production of rhizobacteria, we previously introduced plant-only-based culture media. We herein attempted to widen the scope of plant materials suitable for the preparation of plant-only-based culture media. We chemically analyzed the refuse of turfgrass, cactus, and clover. They were sufficiently rich to support good in vitro growth by rhizobacteria isolates representing Proteobacteria and Firmicutes. They were also adequate and efficient to produce a cell biomass in liquid batch cultures. These culture media were as sufficient as artificial culture media for the cultivation and recovery of the in situ rhizobacteria of barley (Hordeum murinum L.). Based on culture-dependent (CFU plate counting) and culture-independent analyses (qPCR), mowed turfgrass, in particular, supported the highest culturable population of barley endophytes, representing >16% of the total bacterial number quantified with qPCR. This accurately reflected the endophytic community composition, in terms of diversity indices (S’, H’, and D’) based on PCR-DGGE, and clustered the plant culture media together with the qPCR root populations away from the artificial culture media. Despite the promiscuous nature of the plant materials tested to culture the plant microbiome, our results indicated that plant materials of a homologous nature to the tested host plant, at least at the family level, and/or of the same environment were more likely to be selected. Plant-only-based culture media require further refinements in order to provide selectivity for the in vitro growth of members of the plant microbiome, particularly difficult-to-culture bacteria. This will provide insights into their hidden roles in the environment and support future culturomic studies.
著者
Sony S. WIBOWO Natalia TANAN Nuryani TINUMBIA
出版者
Eastern Asia Society for Transportation Studies
雑誌
Journal of the Eastern Asia Society for Transportation Studies (ISSN:18811124)
巻号頁・発行日
vol.11, pp.1507-1521, 2015 (Released:2015-12-26)
参考文献数
24

For Indonesia cities, walking mode, is not yet preferred one because of lack of walking facilities. Walking assessment is needed to evaluate how the walking infrastructure and environment can encourage more walking. The research objective is to develop is walkability measures using the concept of walkability index with case of Bandung city. The index was considered as the quality parameter of walking facilities for ease to walk. Four city areas were used with nine parameters to assess the index. Based on the parameters, a scoring system was developed and to complete it, a survey form was developed and then filled up as an inventory survey along the dominants walking routes within theoretical catchment area of 800 meters from the center area. Research findings show that index for the study areas spread was relatively same. However, detail investigations on the index's parameters showed that were critical condition for walking facilities improvement.
著者
Ono Tomonori S. Galanopoulou Aristea L. Moshé Solomon
出版者
一般社団法人 日本てんかん学会
雑誌
Epilepsy & Seizure
巻号頁・発行日
vol.6, no.1, pp.19-29, 2013

Infantile spasms (IS) are an age-specific epileptic syndrome with overall poor outcome and are recognized as one of the 'catastrophic epilepsies'. Current conventional therapies including adrenocorticotropic hormone and vigabatrin often fail to control the spasms and improve the long-term outcome, especially in cases with structural/metabolic etiologies. To improve this situation, new treatments with a disease modifying potential must be identified. Recent translational studies have led to the development of several animal models of IS that reflect their multiple etiologies. Among these, the multiple hit model has been used to screen new promising therapies that, in the future, may be explored in clinical trials.
著者
The ATLAS Collaboration Hara K. Kim S.H. Okawa H. Sato K. Ukegawa F.
出版者
Elsevier B.V.
雑誌
Physics letters. B (ISSN:03702693)
巻号頁・発行日
vol.765, pp.11-31, 2017-02
被引用文献数
23

A search for dark matter pair production in association with a Higgs boson decaying to a pair of bottom quarks is presented, using 3.2 fb−1 of pp collisions at a centre-of-mass energy of 13 TeV collected by the ATLAS detector at the LHC. The decay of the Higgs boson is reconstructed as a high-momentum b¯b system with either a pair of small-radius jets, or a single large-radius jet with substructure. The observed data are found to be consistent with the expected backgrounds. Results are interpreted using a simplified model with a Z′Z′ gauge boson mediating the interaction between dark matter and the Standard Model as well as a two-Higgs-doublet model containing an additional Z′Z′ boson which decays to a Standard Model Higgs boson and a new pseudoscalar Higgs boson, the latter decaying into a pair of dark matter particles.
著者
高木 伸哉 池田 裕美 川瀬 貴博 長澤 麻央 チョウドリ V.S. 安尾 しのぶ 古瀬 充宏
出版者
Japanese Society of Pet Animal Nutrition
雑誌
ペット栄養学会誌 (ISSN:13443763)
巻号頁・発行日
vol.16, no.2, pp.67-72, 2013

カテコールアミンの前駆体であるL-チロシンの長期投与は慢性ストレスがもたらす行動を緩和することが知られているが、急性ストレス時にL-ならびにD-チロシンの効果を比較した報告はない。本研究では、急性ストレスに対するL-チロシンとD-チロシンの経口投与がマウスの行動に及ぼす影響と脳内の両チロシン濃度に及ぼす影響を調査した。オープンフィールドにおける行動量にL-ならびにD-チロシンの効果は認められなかった。経口投与35分後にL-チロシン投与により血漿L-チロシン濃度は急激に上昇したが、D-チロシンの投与では血漿D-チロシンの緩やかな上昇が観察された。興味深いことに、対照区の各脳部位(大脳皮質、海馬、線条体、視床、視床下部、脳幹ならびに小脳)において、D-チロシンの濃度はL-チロシンの1.8-2.5倍高かった。すべての脳部位において、L-チロシンの投与によりL-チロシン含量は増加したが、D-チロシンの投与でD-チロシン濃度の上昇は認められなかった。上記より、急性投与したL-チロシンとD-チロシンは行動量に影響しないが、L-チロシンとD-チロシンの脳内移行の様相は異なると結論づけられた。
著者
S. M. Lutfor RAHMAN Eiji NAWATA Tetsuo SAKURATANI
出版者
Japanese Society for Tropical Agriculture
雑誌
Japanese Journal of Tropical Agriculture (ISSN:00215260)
巻号頁・発行日
vol.42, no.1, pp.29-38, 1998-03-01 (Released:2010-03-19)
参考文献数
10

バングラデシュの高温期にトマトを栽培するためには耐乾性品種の育成が強く望まれている.このための基礎資料を得ることを目的として, 日本, アメリカ, バングラデシュなどのトマト16品種の耐乾性を評価した.評価した特性は, 収量・開花数・着果数・着果率・果実重・根及び地上部乾物重・開花までの日数・断水期間である.育苗中の断水処理により, 全ての品種で大きく収量が低下したが, その程度は品種により異なった.収量を含むいくつかの特性を総合的に評価した結果, 小型の果実をつける4品種の中ではチビッコが, 中型果実品種5品種の中ではTM 0126が, 大型果実品種7品種の中ではSevernianinが最も優れていた.また, 小型・中型の果実をつける品種群は, 大型の果実をつける品種群より耐乾性に優れる傾向があった.種々の要因を考慮すると, これらの比較的耐乾性に優れる品種の中でTM 0126が最も優れていると考えられ, 今後の育種及び研究材料として有望であると思われる.
著者
S.A.I. Tirmizi
出版者
Manohar
巻号頁・発行日
1989
著者
A.S. Kapoor P.P. Ojha
出版者
The Ichthyological Society of Japan
雑誌
Japanese Journal of Ichthyology (ISSN:00215090)
巻号頁・発行日
vol.19, no.2, pp.82-88, 1972-09-20 (Released:2010-06-28)
参考文献数
18

ウツボの一種, Muraena undulataの嗅覚器の解剖を行なった.olfactory rosetteは細長く, Burneのrosette column IIと, Batesonのrosette type2に属する.嗅覚表面は非常に良く発達している.この魚は嗅覚が良く発達し, Teichmannの分類によるnose nshesの第3群に属する。
著者
H.A. Yu T. Kaneko S. Otani S. Yoshimura A. Oya
出版者
THE CARBON SOCIETY OF JAPAN
雑誌
TANSO (ISSN:03715345)
巻号頁・発行日
vol.1997, no.178, pp.101-107, 1997-07-30 (Released:2010-06-28)
参考文献数
9
被引用文献数
3 4

It was reported that a photovoltaic cell with carbonaceous film/n-type silicon (C/n-Si) was fabricated utilizing a process in which a carbonaceous film was deposited on an n-type silicon substrate by chemical vapor deposition (CVD) of 2, 5- dimethyl-p-benzoquinone at 500°C The purpose of this work is to study preparation and structure of the carbonaceous film. In this study, the carbonaceous films were made by CVD of 2, 5-dimethyl-p-benzoquinone on a quartz substrate at a temperature between 500 and 1000°C. The 2, 5-dimethyl-p-benzoquinone shows higher reaction activity for carbonization at low temperatures. At low CVD temperatures below 700°C, the carbonization reaction of 2, 5- dimethyl-p-benzoquinone was mainly caused by pyrolysis of its methyl and carbonyl groups. The carbonaceous film deposited at low temperatures below 700°C has a typical amorphous structure, and the one deposited above 700°C has a graphite-like lamellar structure oriented along the substrate.