出版者
鉄道大臣官房研究所
巻号頁・発行日
vol.14, no.4, 1926-04
著者
三上 益弘
出版者
分子シミュレーション学会
雑誌
アンサンブル (ISSN:18846750)
巻号頁・発行日
vol.21, no.4, pp.270-276, 2019-10-31 (Released:2020-10-31)
参考文献数
14

分子動力学法(以下,MD法) は,モンテカルロ法とともに,統計力学の数値解法である.モンテカルロ法は,統計力学の物理量の期待値の公式を,ボルツマン分布を実現する乱数を用いた数値積分により求める方法であり,分子動力学法に比べてより直接的に統計力学と結びついている.一方,分子動力学法は,エルゴード仮説により,分子動力学法で計算される物理量の時間平均値が統計力学で定義される物理量のアンサンブル平均と等しいという仮定の下に統計力学の数値解法となっている.今回は,等温等圧アンサンブルと数値積分法の基礎とその計算方法について説明する.
著者
苙口 友隆 池口 満徳 佐藤 衛
出版者
日本結晶学会
雑誌
日本結晶学会誌 (ISSN:03694585)
巻号頁・発行日
vol.55, no.1, pp.24-31, 2013-02-28 (Released:2013-03-07)
参考文献数
19

The combination of small-angle X-ray solution scattering (SAXS) experiments and molecular dynamics (MD) simulations is now becoming a powerful tool to study protein dynamics in solution at an atomic resolution. We have developed a method called MD-SAXS, in which this combination is used with explicit evaluation of X-ray scattering from water molecules hydrating protein molecules. This method offers a link between low-resolution structural information from SAXS and the three-dimensional high-resolution structure. The study using MD-SAXS method revealed the importance of intrinsic dynamics of DNA-binding protein EcoO109I in its function.
著者
趙 浩衍
出版者
東洋文庫
雑誌
東洋学報 = Toyo Gakuho (ISSN:03869067)
巻号頁・発行日
vol.103, no.4, pp.63-94, 2022-03-17

This article attempts to show that the social and political characteristics of Vietnamese fengshui 風水 are truly informed by genealogical sources, which were written by same Confucian scholars as the theoretical texts of fengshui for promoting their ancestors to gain their favor, thus reflecting socio-political reality. The Doan Family (Đoàn tộc 段族) from Huu Thanh Oai 右淸威 commune, which differs from the widely researched aristocratic elite founders of state politics and rural communities, in that its influence stemmed from its relationship to the Court of Trinh Lords (Trịnh vương phủ 鄭王府) during the 18th century and became the first elite to establish itself through the 19th century state examination system. The Doan family’s genealogy, Đoàn tộc phả 段族譜, was written by a member who had passed the local examination; and for that reason contains no reference to imperial edicts (letters of appointment) or legends regarding the family as pioneering actors in state or village origins. Instead, the Doan family genealogy is designed to strengthen family bonds through fengshui practices, the rich description of which traces the appearance of fengshui in Vietnam at that time. Đoàn tộc phả informs us of three characteristic features of early modern Vietnamese fengshui, the first of which is that while the original fengshui masters were Chinese “Northern people” (bắc nhân 北人), native Vietnamese fengshui masters gradually appeared, indicating the penetration of fengshui into rural society. It is clear that the work’s author, a Confucian scholarbureaucrat with a rich knowledge of fengshui, desired to use fengshui ideas rooted in his country’s history, not in China’s. Secondly, each fengshui episode in Đoàn tộc phả is connected to fengshui theory in order to legitimate the history of the Doan family in each era. And finally, Vietnamese fengshui purports that family descendants can gain favor from matrilineal ancestors. Sons-in-law in fact become interested not only in the funeral and memorial services of their wives’ families, but also in the relocation of their mausolea, which shows incorporation of the Southeast Asian custom of bilateral descent in fengshui practices.
著者
Yoshimasa Kanawaku
出版者
The Medical Association of Nippon Medical School
雑誌
Journal of Nippon Medical School (ISSN:13454676)
巻号頁・発行日
vol.89, no.1, pp.33-39, 2022-02-25 (Released:2022-03-11)
参考文献数
46
被引用文献数
2

In Japan, deaths in bathtubs or bathtub deaths are frequently investigated as unnatural deaths. About 19,000 bathtub deaths occur annually in Japan. This pattern of death has become a social issue in forensic pathology and emergency medicine and public health. It is assumed that the death of an adult by drowning in a bathtub cannot be avoided due to disturbance of consciousness. The PubMed database was used for literature search using the retrieval words, "bathing "OR" bathtub "AND" submersion "OR" drowning "OR" death "OR" cardiopulmonary arrest". From the epidemiological characteristics and pathophysiological findings of bath mortality in Japan, three etiologies of impaired consciousness have been proposed: acute ischemic heart failure, heatstroke, and blood pressure fluctuation. Moreover, other causes such as epilepsy and alcohol or drug intake cannot be ignored as potential risks for death in a bathtub. It is also important to note the possibility of suicide and, although extremely rare, homicide in a bathtub. Despite research, the exact causal relationship between bathtub bathing and death remains unclear. Further, the cause of death by postmortem investigation is not always easily determined. Hence, it is desirable to carry out a field survey of causes of death, including bathing conditions, and, wherever possible, a complete autopsy survey. An exclusion of critical cases such as crime-related death, suicide, drug poisoning, and carbon monoxide poisoning is optimal. Of the many hypotheses about the causes of bathtub mortality, the most consistent hypothesis will be medically inferred from the death history, case findings, and test results.
著者
孫 林 武藤 慎一 徳永 澄憲 沖山 充
出版者
日本地域学会
雑誌
地域学研究 (ISSN:02876256)
巻号頁・発行日
vol.36, no.1, pp.113-131, 2006 (Released:2007-06-05)
参考文献数
10
被引用文献数
1

The Chinese government is examining to introduce some environmental and energy policies like as the fuel tax, mileage regulation or tax reduction to low-emission vehicles, to the situation that the load rests upon environmental energy by the rapid growth of automobile market in Chinese. In this paper, we evaluated the environmental or economic impacts generated by introducing such environmental and energy policies by applying the dynamic computable general (DCGE) equilibrium model.From the results of numerical simulation, we obtained the some implications that the setting of high fuel tax level was necessary to regulate fuel consumption more effectively, mileage regulation was most effective policy to fuel reduction and the tax reduction like as Green tax or subsidy policy was necessity to change the type of car to low-emission vehicles.JEL classification: H23, Q51, Q58
著者
嶋矢 志郎
出版者
日本開発工学会
雑誌
開発工学 (ISSN:13437623)
巻号頁・発行日
vol.31, no.1, pp.75-80, 2011 (Released:2012-12-20)
参考文献数
9

Fukushima Daiichi nuclear disaster caused by the March 11 Japan earthquake and tsunami in 2011 is one of historical lessons for us, human beings. It suggests us that it is the time for us to sincerely consider shift of civilization. We, the people of all over the world, together must now accelerate Paradigm shift from self centered material civilization confronting nature to life centered environmental civilization harmonizing with nature in order to help crisis of the Earth and human beings and change world trend.We come to the conclusion that we must change our lifestyle from self centered shallow ecology to life centered deep ecology. Thus it is important for us to be engaged in advocating "Promotion for Ethical oriented lifestyle" which means that we are true to keep our lifestyle to be ethical way and we try to aufheben (improve) the 21st century to be "the ethical oriented century" not remaining to be only "the century of environment."
著者
大西 みさ 足立 はるゑ 中村 小百合
出版者
一般社団法人 日本看護研究学会
雑誌
日本看護研究学会雑誌 (ISSN:21883599)
巻号頁・発行日
vol.27, no.1, pp.1_83-1_89, 2004-04-01 (Released:2016-03-31)
参考文献数
50

本研究の目的は,糖尿病患者の指尖のSMBG穿刺痛を軽減する為に考案した氷冷法について,血糖自己測定法(SMBG)としての有効性と妥当性を検討することである。氷冷法とは,冷蔵庫で保管した2℃氷水に指を15又は20秒間浸して穿刺する指尖採血法である。対象は,A病院の糖尿病患者50名と健常人(医療スタッフ)20名であり,従来法と氷冷法を比較し,以下の結果を得た。1)氷冷法は冷却作用から痛覚が消失し従来法よりも糖尿病患者(p<0.01),健常人(p<0.001)共に痛み閾値が上昇した。2)氷冷法は一定の血液量が確保でき,従来法と同様に血糖値の誤差がほとんどなく,SMBGの妥当性に問題はなかった。このことから,氷冷法は指尖の穿刺痛が軽減できる新しいSMBG方法であり,穿刺痛による負担を軽減できることから糖尿病患者のQOL向上に貢献できる可能性が示唆された。
著者
奥田楽々斎 著
出版者
臨川書店
巻号頁・発行日
vol.下巻, 1987
著者
野崎 剛弘 須藤 信行
出版者
一般社団法人 日本心身医学会
雑誌
心身医学 (ISSN:03850307)
巻号頁・発行日
vol.53, no.1, pp.20-28, 2013-01-01 (Released:2017-08-01)
参考文献数
10

生活習慣病の一つである2型糖尿病では,食事や運動といった薬物以外の自己管理に委ねる割合が高い.自己管理の成否には,患者の心理社会的要因が少なからず影響を及ぼす.したがって,心身両面から患者を理解し治療していくという心身医療(心身医学的アプローチ)は,糖尿病の臨床において大きな効果を発揮する.本稿では,まず2型糖尿病患者に対する心身医療について述べ,次に2型糖尿病患者の血糖コントロールに影響を及ぼす心理・社会的因子を縦断的に調査した自験例を紹介し,最後に通常の内科的治療では血糖コントロールが不良であった患者が心身医療によって良好な血糖コントロールとなり維持している症例を提示する.
著者
瀧井 正人
出版者
一般社団法人 日本心身医学会
雑誌
心身医学 (ISSN:03850307)
巻号頁・発行日
vol.53, no.1, pp.12-19, 2013-01-01 (Released:2017-08-01)
参考文献数
21

1型糖尿病は,若年発症,インスリン注射の必要性,少数派ゆえの周囲の無理解など,病気に関する負担は大きく,心理社会的問題の頻度は高く概して重篤である.1994年以降に当科を受診した,心理社会的問題を抱えた1型糖尿病患者約250名のうち,実に約7割が摂食障害を併発していた.若い1型糖尿病女性の約1割に摂食障害が併発しているといわれており,血糖コントロールの著しい悪化,糖尿病合併症の早期の発症・進展など医学的な問題も大きい.一方,インスリン注射の不適切な使用などによる自己破壊的行動は,1型糖尿病におけるもう一つの重大な問題である.本稿では,これらの2つの問題を中心に,その病態と治療・対策について述べた.
著者
Daiichiro ISHIGAMI Satoshi KOIZUMI Satoru MIYAWAKI Hiroki HONGO Yu TERANISHI Jun MITSUI Nobuhito SAITO
出版者
The Japan Neurosurgical Society
雑誌
NMC Case Report Journal (ISSN:21884226)
巻号頁・発行日
vol.9, pp.139-144, 2022-12-31 (Released:2022-05-31)
参考文献数
17
被引用文献数
2

Stenotic developmental venous anomalies (DVAs) often present with neurological deficits. In addition, cerebral capillary telangiectasia (CCT) coexisting with DVA is rarely encountered, and its pathophysiology, including the underlying genetics, and appropriate management remain uncertain. A 46-year-old man without any medical history of note was referred to our hospital with gradually worsening cerebellar ataxia. Two months after symptom onset, ataxic dysarthria and gait emerged. Brain magnetic resonance imaging showed CCT occupying the pons and left cerebellar peduncle. Subsequent catheter angiography demonstrated a DVA leading from the mass into the cavernous sinus with marked outlet stenosis and flow stagnation. We hypothesized that venous congestion was the source of gradual neurological deterioration and therefore initiated anticoagulation. Symptoms showed mild improvement, and his neurological status has remained stable as of 1 year after symptom onset. Whole-exome sequencing of germline DNA did not reveal any rare variants in genes previously reported as pertinent to vascular malformations. Anticoagulation may be a useful option in patients with non-thrombotic, stenotic DVA for whom neurological status did not improve under expectant management. Genetic analysis of this patient did not reveal any pathogenic mutations, and further investigation of somatic mutations is necessary to elucidate potential genetic causes.
著者
千葉 堯
出版者
一般社団法人 日本教育心理学会
雑誌
教育心理学研究 (ISSN:00215015)
巻号頁・発行日
vol.13, no.2, pp.82-90,125, 1965-06-30 (Released:2013-02-19)
参考文献数
7

The purposes of this study were (a) to consider Jean Piaget's theory on conservation (especially conservation of liquid and weight), and (b) to analyse the role or meaning of nonconservation.Hypotheses: (1) Even if the child does not exhibit conservation in Piaget's classic experiments, we cannot say that he has no conservation.(If we admit, as Piaget, that the child cannot acquire conservation without logical multiplication or conceptual coordination, we must reject our hypothesis.)2) Because of perceptual and (other conditions inhibiting the child from exhibiting conservation, the child who has acquired conservation cannot exhibit conservation if conditions change.Procedure: Our Subjects were 71 primary school pupils (6-9 years old).1) Piaget's classic ex (periments of conservation2) Conservation of liquid by usin g screened beakers: Two standard _beakers are partly filled so that the child judges them to contain equal amounts of water.Another beaker which is hidden by a screen except for the top is introduced.The Experimenter pours from a standard beaker into the screened one.Then the child is asked which has more to drink, or do they have the same amount.(3) Quantification of liquid: Two beakers, A and B (A is wider than B) are partly filled, and two empty beakers (one is identical with B and the other is smaller than A and B in both height and width) are introduced.The child is asked,“Which has more to drink, A or B?”, and informed,“If you want to use these empty beakers, you may use them.”Results: (a) In comparison with the classic experiment, there is a striking increase in correct equality judgment in the screened experiment.(b) Without a concept of conservation, it is impossible for the child to quantify liquid.(c) The child justifies his correct judgment not by logical multiplication but by noting that “You only poured it” or “Its the same water.” (d) When the child acquires conservation and his concept of conservation is f ixed to some extent, he exhibits nonconservation.Judging from out results, we cannot explain result (a) and (d) by Piaget's theory.The child discovers essential causality by falling into nonconservation. In this way, he generalizes and develops his concept of conservation, and in this sense, the role of nonconservation is very important for the development of concept of conservation.