著者
高橋 昭
出版者
一般社団法人 日本内科学会
雑誌
日本内科学会雑誌 (ISSN:00215384)
巻号頁・発行日
vol.82, no.1, pp.34-40, 1993-01-10 (Released:2008-06-12)
参考文献数
10

頭痛患者へのアプローチは,常に全身的な分析が必要である.診断の第一歩は注意深い問診であり,発病様式,発現場所,痛みの性質,強さ,持続,頻度,発現時間,随伴症状,増悪,軽減因子などについての情報を的確に得ることが重要である.社会歴や家族歴も重要な鍵を提供することがある.次いで全身のベッドサイド診療と神経学的検査を行い,この所見を基にCT, MRI,髄液検査など特殊検査の計画を立てる.
著者
高橋 昭
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.75, no.1special, pp.266-273, 1982 (Released:2011-11-04)
参考文献数
23

Fisher's syndrome comprises ophthalmoplegia, ataxia and areflexia. The clinicoanatomical correlation and the nosological situation have been disputed since the first description by Fisher in 1956. The accumulated data indicate that the syndrome is a demyelinative process of peripheral nerves and is to be linked with the Guillain-Barré-Strohl syndrome.Eight patients with Fisher's syndrome were examined in order to study the site of lesion responsible for ataxia. The nature of ataxia was considered to be not segmental incoordination but static or locomotor ataxia, because of the lack of ataxia in the extremities and in speech even when the patients were unable to stand or sit. Vibratory sensation was severely impaired in the majority of the cases. Some patients had unique distribution of proximal dominancy. Both the severity and clinical course of dysequilibrium had intimate relations to those of the vibratory disorder. No clinical or laboratory findings were obtained which suggested vestibulocerebellar dysfunction.Morin's spino-cerevico-thalamic tract has been recently proposed as a possible pathway of vibratory sensation and equilibrium. A sole autospied case was reported by Richter (1962) who demonstrated the restricted degeneration of Flechsig's middle root zone in the posterior column of the spinal cord which relays vibratory and proprioceptive sensations via Morin's tract to the cerebrum and cerebellum.It is concluded that the events of vibratory sensory loss connected with dysequilibrium seem to be important in these respects.
著者
高橋 昭
出版者
一般社団法人 日本内科学会
雑誌
日本内科学会雑誌 (ISSN:00215384)
巻号頁・発行日
vol.79, no.3, pp.350-353, 1990-03-10 (Released:2008-06-12)
参考文献数
4
著者
田中 知
出版者
一般社団法人 日本原子力学会
雑誌
日本原子力学会誌ATOMOΣ (ISSN:18822606)
巻号頁・発行日
vol.55, no.3, pp.152-160, 2013 (Released:2019-10-31)

本稿は,平成24年7月24日に開催された日本学術会議シンポジウム「巨大災害から生命と国土を護る―24学会からの発信」の第6回「原発事故からエネルギー政策をどう立て直すか」における講演をもとに書き下ろした。講演から半年以上経過しているが,現在においても有用な議論の材料となりえる内容であると思う。 まず,我が国のエネルギー政策が掲げていた基本的視点および原子力エネルギーの位置付けについて述べる。次に,事故によって顕在化された原子力エネルギー利用のリスクを5つの視点から提示し,原子力災害リスクを低減するためになすべきことについて提言する。最後に,講演当時におけるエネルギー政策の方向性について確認し,原子力エネルギーを利用する本来的な意味についてまとめる。 原子力発電所の事故におけるリスクをどのように低減することができるか,エネルギーの安定供給性に係るリスクをどのように考えればよいのか,など,多角的な視点からエネルギーを考える一助となれば幸いである。
著者
高橋 昭
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.76, no.9special, pp.2354-2362, 1983-09-15 (Released:2011-11-04)
参考文献数
16

Multiple cranial nerve palsy can occur in various intracranial or juxtacranial diseases including neoplasm, granuloma, angiopathy and meningeal diseases, or in acute or chronic relapsing polyneuropathy of demyelinating nature. The latter condition is characterized by symmetrical or bilateral, and predominantly motor nerve involvement.In 1967, the author described a peculiar, multiple, cranial nerve palsy and proposed the descriptive designation of migrating, disseminated, multiple, cranial neuropathy. Since then, 9 cases have been reported from Japan and 3 case series have been known from Thailand, Sri-Lanka and Finland.The cranial nerve palsy in this disease is acute in onset, usually self-limited in course, and migrates with latent interval. All of the sensori-motor cranial nerves II-XII may be involved. Repeated and careful examination and long-term follow-up study failed to disclose any evidence of systemic or local underlying disease processes.In this report, 10 of our own cases are described. Paralysis of the vestibulo-Cochlear nerve was found in 5 patients. Neurological and neuro-otological studies disclosed that hearing loss was of sensori-neural type and the vestibular dysfunction was due to peripheral origin. One of these was found to have benign paroxysmal positional vertigo.Attention should be given to those presenting with vestibulo-cochlear symptoms and signs, especially with a tendency to relapse, in relation to migrating, disseminated, multiple, cranial neuropathy.
著者
高橋 昭
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.75, no.11special, pp.2383-2391, 1982 (Released:2011-11-04)
参考文献数
23
被引用文献数
2 1

In 1916 three French neurologists, Guillain, Barré and Strohl, presented their important paper describing 2 patients with polyneuritis. They emphasized the predominant motor weakness of the limbs with minimal sensory loss, hyporeflexia, elevated protein level in cerebrospinal fluid without cellular reaction and favourable prognosis. Since that time, the syndrome has been referred the Guillain-Barré syndrome, but the diagnostic limits of the disorder had been disputed because of inclusion of many types of acute and chronic polyneuritis under this title. In 1960, Osler and Sidell published a paper and set down diagnostic criteria which severely restricted the definition of the disorder. A new diagnostic criteria for the disorder was clearly proposed for field studies by an ad hoc NINCDS committee (1978) and Asbury (1981). These clinical study yields pathological and experimental evidences suggesting that GBS is an acute immune-mediated polyneuropathy (AIMP) and a distinctive entity. GBS is now one of the most frequent forms of acute polyneuritis.Vestibular neuronitis is the term applied originally by Dix and Hallpike (1952) to a distinctive disturbance of vestibular function, characterized clinically by an abrupt and usually a single and severe attack of vertigo and by an absence of cochlear abnormality. The pathological site of the vestibular pathway and the nature of the affection have not been established. Consequently, there is confusion regarding its nosological situation.In this article, the diagnostic criteria of the Guillain-Barré syndrome are reviewed and vestibular neuronitis is compared with it in order to refine the definition. In considering the clinical characteristics, there is some similarlity between vestibular neuronitis and Guillain-Barré syndrome. The only significant difference is that vestibular neuronitis is confined primarily to the vestibular nerve. Thus, it is suggested that vestibular neuronitis should be investigated in future with relation to AIMP as well as from the viewpoint of directly infectious or vascular etiology.
著者
余晓栋 胡祖平著
出版者
人民出版社
巻号頁・発行日
2018
著者
勝沼 孝臣 渡沼 敏夫 加藤 義治 関 啓介 金子 貴広 村上 洋 清水 礼子 久野 敏行
出版者
公益社団法人 日本口腔インプラント学会
雑誌
日本口腔インプラント学会誌 (ISSN:09146695)
巻号頁・発行日
vol.28, no.2, pp.168-174, 2015-06-30 (Released:2015-08-01)
参考文献数
13

The first requirement of implant treatment is to obtain sufficient bone quantity in the implant placement area. We have developed a method to obtain new bone and bone apposition nonsurgically using minor tooth movement (MTM) before insertion of implants. Here, we report two cases treated using this approach that both had satisfactory outcomes. Case 1 was a 46-year-old woman with insufficient vertical bone quantity in the area where the maxillary right first molar was lost. There was some distance between the root apex of the second premolar and maxillary sinus. In this case, the maxillary second premolar was distally moved to the area of tooth loss using MTM. The period of orthodontic treatment was 13 months. An implant was inserted in the original area in which the second premolar had been present. The superstructure was then placed on the implant. Four years have passed since this treatment and the outcome is satisfactory. Case 2 was a 29-year-old man with insufficient vertical bone quantity in the area where the maxillary right first molar had existed. The root apex of the second premolar touched the maxillary sinus. The maxillary second premolar was distally moved using MTM. The period of orthodontic treatment was 10 months. An implant was inserted into the newly made space and the superstructure was placed on the implant. Metamorphosis was observed in the remodeled bone wall of the maxillary sinus attached to the distal part of the moved maxillary second premolar. After three years and two months, the outcome is favorable. These two cases show that the MTM approach makes it possible to obtain new bone and bone apposition and to insert an implant in the newly made space in the original bone.
著者
三浦 覚
出版者
THE JAPANESE FORESTRY SOCIETY
雑誌
日本林学会誌 (ISSN:0021485X)
巻号頁・発行日
vol.82, no.2, pp.132-140, 2000-05-16 (Released:2008-05-16)
参考文献数
36
被引用文献数
12

林地表層における雨滴侵食保護に関わる林床の被覆状態を明らかにするために,林床植生および堆積リターの両者による総合的な被覆指標として林床被覆率を新たに定義し,急傾斜地にあるヒノキ,スギ,アカマツ,落葉広葉樹林の林床の被覆状態を評価した。その結果,スギ,アカマツ,落葉広葉樹林の林床被覆率は,林齢によらず常に90%以上で高かった。一方,ヒノキ林の林床被覆率は,10~20年生の幼~若齢期に著しく低下し,40年生前後の壮齢期に林床植生が回復し始めるまで低い状態が続いた。林床被覆率を支配する因子は,スギ,アカマツ,落葉広葉樹林では堆積リターであったが,ヒノキ林では林床植生であった。林床被覆率とこれに対する林床植生および堆積リターの寄与の強さは,樹種や林齢によって大きく変化する。したがって,林床の被覆状態を評価するためには,林床植生と堆積リターの消長の特質を明らかにし,林床被覆率のように両者による被覆を一体として捉えうる指標を用いる必要がある。
著者
池井 優
出版者
慶應義塾大学法学研究会
雑誌
法學研究 : 法律・政治・社会 (ISSN:03890538)
巻号頁・発行日
vol.68, no.1, pp.53-74, 1995-01

はしがき第一章 中国への修学旅行実施と事故の発生 一 修学旅行実施の背景と事故 二 情報の遅れと混乱第二章 事故発生直後の日中交渉第三章 補償交渉 一 日中補償交渉の問題点 二 日中補償交渉の展開 三 団長間交渉結び中村勝範教授退職記念号
著者
河内 明夫 冨重 恵利紗 柴田 由香里 鳴海 恵子 園田 純一郎 武田 泰生 本屋 敏郎
出版者
一般社団法人 日本プライマリ・ケア連合学会
雑誌
日本プライマリ・ケア連合学会誌 (ISSN:21852928)
巻号頁・発行日
vol.36, no.2, pp.99-105, 2013 (Released:2013-07-01)
参考文献数
7
被引用文献数
1

要 旨目的 : 地域住民を対象とした調剤報酬講義により保険薬局における医療費の内容について理解を促し, それが受講者の保険薬局の選択に影響を及ぼすか否かについて検討した. 方法 : 受講者34名に対し, 講義前後アンケートを実施した. 解析対象はアンケートに記入不備のなかった29名とした. 結果 : 保険点数付き領収証を見たことがないと回答した受講者は34.5%であり, 保険点数を理解した上で支払っていたとの回答は25.0%であった. 講義後, 保険薬局の業務内容において服薬指導は55.2%の上昇, 調剤, 薬歴管理及び疑義照会はそれぞれ27.6%, 27.6%及び20.7%の上昇を示した. 講義後, 薬局選択の理由は病院近くの薬局で37.9%の減少, 薬の説明指導がしっかりしている薬局や相談対応の良い薬局ではそれぞれ72.5%, 20.7%の上昇となった. 結論 : 調剤報酬を学ぶことによって地域住民が保険薬剤師の職能を理解することは保険薬局の選択に好影響を与える可能性が示唆された.
著者
Takuo Kubota Masanori Adachi Taichi Kitaoka Kosei Hasegawa Yasuhisa Ohata Makoto Fujiwara Toshimi Michigami Hiroshi Mochizuki Keiichi Ozono
出版者
The Japanese Society for Pediatric Endocrinology
雑誌
Clinical Pediatric Endocrinology (ISSN:09185739)
巻号頁・発行日
vol.29, no.1, pp.25-42, 2020 (Released:2020-01-09)
参考文献数
79
被引用文献数
19

Achondroplasia (ACH) is a skeletal dysplasia that presents with limb shortening, short stature, and characteristic facial configuration. ACH is caused by mutations of the FGFR3 gene, leading to constantly activated FGFR3 and activation of its downstream intracellular signaling pathway. This results in the suppression of chondrocyte differentiation and proliferation, which in turn impairs endochondral ossification and causes short-limb short stature. ACH also causes characteristic clinical symptoms, including foramen magnum narrowing, ventricular enlargement, sleep apnea, upper airway stenosis, otitis media, a narrow thorax, spinal canal stenosis, spinal kyphosis, and deformities of the lower extremities. Although outside Japan, papers on health supervision are available, they are based on reports and questionnaire survey results. Considering the scarcity of high levels of evidence and clinical guidelines for patients with ACH, clinical practical guidelines have been developed to assist both healthcare professionals and patients in making appropriate decisions in specific clinical situations. Eleven clinical questions were established and a systematic literature search was conducted using PubMed/MEDLINE. Evidence-based recommendations were developed, and the guidelines describe the recommendations related to the clinical management of ACH. We anticipate that these clinical practice guidelines for ACH will be useful for healthcare professionals and patients alike.
著者
Yuan-Qing Fu Ju-Sheng Zheng Bo Yang Duo Li
出版者
Japan Epidemiological Association
雑誌
Journal of Epidemiology (ISSN:09175040)
巻号頁・発行日
pp.JE20140120, (Released:2015-03-14)
参考文献数
52
被引用文献数
15 33

Epidemiological studies have suggested inconsistent associations between omega-3 polyunsaturated fatty acids (n-3 PUFAs) and prostate cancer (PCa) risk. We performed a dose-response meta-analysis of prospective observational studies investigating both dietary intake and circulating n-3 PUFAs and PCa risk. PubMed and EMBASE prior to February 2014 were searched, and 16 publications were eligible. Blood concentration of docosahexaenoic acid, but not alpha-linolenic acid or eicosapentaenoic acid, showed marginal positive association with PCa risk (relative risk for 1% increase in blood docosahexaenoic acid concentration: 1.02; 95% confidence interval, 1.00–1.05; I2 = 26%; P = 0.05 for linear trend), while dietary docosahexaenoic acid intake showed a non-linear positive association with PCa risk (P < 0.01). Dietary alpha-linolenic acid was inversely associated with PCa risk (relative risk for 0.5 g/day increase in alpha-linolenic acid intake: 0.99; 95% confidence interval, 0.98–1.00; I2 = 0%; P = 0.04 for linear trend), which was dominated by a single study. Subgroup analyses indicated that blood eicosapentaenoic acid concentration and blood docosahexaenoic acid concentration were positively associated with aggressive PCa risk and nonaggressive PCa risk, respectively. Among studies with nested case-control study designs, a 0.2% increase in blood docosapentaenoic acid concentration was associated with a 3% reduced risk of PCa (relative risk 0.97; 95% confidence interval, 0.94–1.00; I2 = 44%; P = 0.05 for linear trend). In conclusion, different individual n-3 PUFA exposures may exhibit different or even opposite associations with PCa risk, and more prospective studies, especially those examining dietary n-3 PUFAs and PCa risk stratified by severity of cancer, are needed to confirm the results.

1 0 0 0 中国文学史

著者
佐藤一郎著
出版者
慶応通信
巻号頁・発行日
1971
著者
高山 真 岩崎 鋼 渡部 正司 神谷 哲治 平野 篤 松田 綾音 沼田 健裕 楠山 寛子 沖津 玲奈 菊地 章子 関 隆志 武田 卓 八重樫 伸生
出版者
一般社団法人 日本東洋医学会
雑誌
日本東洋医学雑誌 (ISSN:02874857)
巻号頁・発行日
vol.63, no.4, pp.275-282, 2012 (Released:2013-02-13)
参考文献数
10
被引用文献数
2 2

古くからヨーロッパでは自然療法を取り入れて健康を保つ方法が一般的に行なわれてきており,特にドイツでは統合医療に補完・代替医療が積極的に導入されている。ドイツでも有名な4つの施設,ミュンヘン大学麻酔科ペインクリニック,TCM Klinik Bad Ko¨tzting, Immamuel Krankenhaus, ZenHaus Klinik を視察し統合医療の現状を報告する。各施設では,慢性疼痛に対する4週間プログラム,中国伝統医学中心の治療,自然療法主体の治療,日本伝統医学にアロマテラピーを加えた治療など,各々の施設で特徴的な治療方法が行なわれていた。ドイツでは多くの病院,クリニックで補完・代替医療が盛んに行なわれているが,その広がりの一つにドイツにおける医療保険制度が挙げられる。公的保険では治療の一部,プライベート保険では広い範囲で補完・代替医療に対する保険償還が行なわれる。歴史的背景に加え,このような制度も統合医療の広がりに影響を与えていると考える。