著者
Yasuharu Tokuda Masahiro Koizumi Gerald H. Stein Richard B. Birrer
出版者
The Japanese Society of Internal Medicine
雑誌
Internal Medicine (ISSN:09182918)
巻号頁・発行日
vol.48, no.7, pp.537-543, 2009 (Released:2009-04-01)
参考文献数
33
被引用文献数
6 10

Objective To derive and validate a clinical prediction model with high sensitivity for differentiating aseptic meningitis (AM) patients from bacterial meningitis (BM) patients. Methods We developed the model using the derivation cohort in a community rural hospital in Okinawa and assessed its performance using the validation cohort in a metropolitan urban hospital in Tokyo. There were 66 (39.5%) and 5 (17.9%) adult patients with BM among the derivation (n=167) and the validation cohort (n=28), respectively. Recursive partitioning analysis was used to determine the important classification variables and to develop a sensitive model to safely exclude BM. Results The model produced high- and low-risk groups based on the following: 1) Gram stain, 2) CSF neutrophil percent ≤15%, 3) CSF neutrophil count ≤150 cells/mm3, and, 4) mental status change. Among the derivation cohort, there were 65 patients with BM in the high-risk group (n=76), while only one patient with BM was noted (sensitivity, 99%) in the low-risk group (n=91). Among the validation cohort, there were 5 patients with BM in the high-risk group (n=7), while no patient was classified with BM (sensitivity, 100%) in the low-risk group (n=21). Conclusion This simple and sensitive model might be useful to safely identify low-risk patients for BM who would not require antibiotic treatment.

1 0 0 0 OA 町方書上

出版者
巻号頁・発行日
vol.[31] 本郷町方書上 参止,

1 0 0 0 OA 通言総籬

著者
山東京伝 作
出版者
蔦屋重三郎
巻号頁・発行日
1787
著者
斉藤 聡 小山 広毅 八島 孝久 緒方 浩之
出版者
一般社団法人 映像情報メディア学会
雑誌
テレビジョン学会技術報告
巻号頁・発行日
vol.15, no.63, pp.27-32, 1991

Recently, NHK intends to enrich services for local viewers by increasing local or regional programs from the local TV stations. This attempt is not convenient for informing nationalwide urgent-news, because every station broadcasting its own program have to superimpose the information quickly and surely. The Nationalwide Urgent-news Superimposing System developed to solve this problem. This system has been built on the fundamental facilities of News Center (NC), NHK Tokyo.
出版者
巻号頁・発行日
vol.[4],
著者
川井 博義
出版者
筑波大学倫理学原論研究会
雑誌
倫理学 (ISSN:02890666)
巻号頁・発行日
no.21, pp.61-74, 2005

世間を 無常ものと 今ぞ知る 奈良の都の うつろふ見れば (巻六、一〇四五、作者不審) 天平十二年(七四〇年)十月末、伊勢に向かった聖武天皇は、その二ヶ月後、久邇京遷都を決定するその四年後、聖武天皇は ...
著者
大櫛 陽一 浜 六郎 浜崎 智仁 内野 元
出版者
日本脂質栄養学会
雑誌
脂質栄養学 (ISSN:13434594)
巻号頁・発行日
vol.27, no.1, pp.39-47, 2018 (Released:2018-07-16)

A nationwide multicenter randomized controlled study (JDCS) was performed in type-2 diabetes patients. The conventional (CON) group received usual care including anti-diabetic, anti-hypertensive and anti-hyperlipidemic agents to maintain their targeted levels, and the intervention (INT) group additionally received intensive education on lifestyle modifications and adherence to treatment by telephone counselling and at each time outpatient clinic visit for 8 years. The JDCS appears to be based on an assumption that usual treatment of diabetes is appropriate for the prevention of diabetes complications, and that the lack of patients’ compliance is the major cause of unsuccessful treatments. No significant differences between the two groups were found in most of the test results (BMI, blood pressure, fasting glucose level, TC, HDL, lipoprotein-a), use of agents, life style (energy intake, smoking and alcohol intake) at 4 years of intervention. The exercise level was higher at 5 years of intervention, and triglyceride level was lower at 8 years. The incidence of coronary heart disease, retinopathy and neuropathy did not differ significantly between the two groups, but stroke incidence was lower in the INT group. We conducted new analyses on the changes of some explanatory variables in each group. The proportion of participants with pharmacological treatment including insulin significantly increased in both groups except sulfonylureas which about 60% of the participants used at the baseline. On the other hand, those without pharmacological treatment decreased from 19% to 4% in both groups. These indicate that both groups failed in diabetes treatment together. As for the exercise and the smoking cessation, these may prevent stroke, but do not contribute to improvement of diabetes. It is not convincing enough for us to support the validity of publicizing the treatment of diabetes patients used in the JDCS study performed at 59 universities and general hospitals in Japan.
著者
菅原 詩緒理
出版者
日本脂質栄養学会
雑誌
脂質栄養学 (ISSN:13434594)
巻号頁・発行日
vol.27, no.1, pp.7-13, 2018 (Released:2018-07-16)

Lifestyle diseases such as cancer, heart disease, cerebrovascular disease, are the three leading causes of death among the Japanese, and the prevention of lifestyle diseases is an important issue in Japan. Daily high energy intake and high fat diet are involved in the onset of lifestyle diseases, and nutritional therapy is important for the prevention of lifestyle diseases. Nutritional therapy for lifestyle diseases is based on scientific data which is important to be established. The authors found that lipid nutrition for insulin resistance and non-alcoholic fatty liver disease (NAFLD) from the association of physical measurement, clinical data, nutrient intake and plasma fatty acid composition. As a result, it was suggested that the low levels of n-3 Polyunsaturated Fatty Acids (n-3 PUFA) in plasma phospholipid may be related to insulin resistance, and the decrease in n-3 PUFA intake was also involved in the rise in n-6/n-3 ratio. It was also suggested that increasing NAFLD Score not only reduces energy intake, but also increases fish and n-3 PUFA intakes. The clarification that n-3 PUFA intakes of eicosapentaenoic acid and docosahexaenoic acid is involved in the prevention and improvement of lifestyle related diseases in elucidating the nutritional therapy of lipids in lifestyle related diseases has revealed the importance of lipid nutrition in lifestyle related diseases. It is thought that it contributes to the establishment of nutritional therapy of lipid.
著者
奥山 治美 笠本 進一 浜崎 智仁
出版者
日本脂質栄養学会
雑誌
脂質栄養学 (ISSN:13434594)
巻号頁・発行日
vol.27, no.1, pp.21-29, 2018-03-31 (Released:2018-07-16)

The Japan Atherosclerosis Society Guidelines for the Prevention of Atherosclerotic Cardiovascular Diseases (JASGL) were based on “the lower, the better” hypothesis. However, we published Cholesterol Guidelines for Longevity 2010 based on the fact that cholesterol levels are inversely associated with all-cause mortality among general populations aged at 40 years and over. Here, we summarized the mechanisms of atherogenesis caused by statins and some types of vegetable oils with strokestimulating activity in the rat; they inhibit the VK1-VK2- osteocalcin target organs link, leading to artery calcification and lifestyle-related diseases. The mainstay of JASGL 2017 is the Suita study published in 2014, which is much smaller than the previous epidemiological study, NIPPONDATA 80, for JASGL 2012. Besides, the total and cardiovascular mortality of the study has not been published yet. We found some terrible mathematical errors that cannot be simple calculation mistakes. For example, deleting some study subjects actually increased the number of male participants instead. It is likely that no consistent epidemiological studies are available any more to JAS to protect their cholesterol hypothesis. JASGL 2017 calculated risk of coronary artery disease (CAD) in Japan where the incidence is very low. Then the story was fabricated to protect their notion that even the group with a very low risk in the world standard was classified as middle to high risk groups of CAD, which can lead to unnecessary medication. The GLs are disguised as those based on the cholesterol hypothesis; actually it became very clear that they are simply selling tools for statins.
著者
[豊田天功] [著]
巻号頁・発行日
vol.[227], 1800
著者
渡邊 香 鈴木 秀和
出版者
日本知能情報ファジィ学会
雑誌
日本知能情報ファジィ学会 ファジィ システム シンポジウム 講演論文集
巻号頁・発行日
vol.27, pp.44-44, 2011

当研究室が出場している中型リーグは,ロボットが完全に自律しており,カメラなどのセンサのみで環境を認識し,判断・行動している.RoboCupでは年々自己位置同定技術の重要性が高まっており,ボールをゴールに運ぶだけでなく,フリーキックやパスなどの戦術的な面でも注目されている.介護・福祉ロボットやホームロボットなど人間と共生するロボットは人と同様の環境認識・行動判断能力が求められている.自己位置同定技術はこれらのロボットへの応用も期待できる.RoboCupにおけるサッカーフィールド環境では様々なセンサを用いることで,自己位置同定に必要な指標をいくつか得ることができる.これらの指標を大きく二つに分類すると,エンコーダによる移動情報や電子コンパスなどから得られる内部情報と,カメラ画像などから得られる外部(周囲)情報に分けられる.本報告では,これらの情報を用いて自己位置同定の検証を行う.

1 0 0 0 三國誌後傳

著者
(明) 酉陽野史編次
出版者
上海古籍出版社
巻号頁・発行日
1990
出版者
天一出版社
巻号頁・発行日
1985