著者
Masanori KOBAYASHI Akiko SAITO Yoshikazu TANAKA Masaki MICHISHITA Masato KOBAYASHI Mami IRIMAJIRI Takeharu KANEDA Kazuhiko OCHIAI Makoto BONKOBARA Kimimasa TAKAHASHI Tatsuya HORI Eiichi KAWAKAMI
出版者
公益社団法人 日本獣医学会
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
vol.79, no.4, pp.719-725, 2017 (Released:2017-04-05)
参考文献数
32
被引用文献数
23

Canine prostate cancer (cPCa) is an untreatable malignant neoplasm resulting in local tissue invasion and distant metastasis. MicroRNAs (miRs) are small non-coding RNAs that function as oncogenes or tumor suppressors. The purpose of this study was to characterize the expression of miRs that are altered in cPCa tissue. The expression levels of 277 mature miRs in prostatic tissue (n=5, respectively) were compared between the non-tumor and tumor groups using real-time PCR. Five miRs (miR-18a, 95, 221, 222 and 330) were up-regulated, but 14 miRs (miR-127, 148a, 205, 299, 329b, 335, 376a, 376c, 379, 380, 381, 411, 487b and 495) were down-regulated specifically in cPCa (P<0.05). These miRs have potential use as early diagnosis markers for cPCa and in miR-based therapy.
著者
上野 美香
出版者
広島大学大学院国際協力研究科
雑誌
国際協力研究誌 (ISSN:13410903)
巻号頁・発行日
vol.18, no.3, pp.123-136, 2012-03

This study is a part of the knowledge acquired through research fieldwork at a nursing care facility in Japan. This paper focuses on the practical issues of Indonesian care workers under the EPA scheme from the view points of the candidates and the Japanese language teacher. The purpose of this research is to clarify the present situation of the actual facility where they accept the candidates, and to try to discuss the ways of feasibly supporting candidates and the care site.Foreign care worker candidates under the EPA have been accepted since 2008, and they started On-the Job Training in various parts of Japan. However, this scheme has a lot of issues involving language, the system framework, communication in intercultural care, etc. Although it seems to not be concluded in arguments that relate to many fields, one particularly severe situation involves linguistic issues; acquiring Japanese language and the measures to pass the national examination.One of the findings throughout the fieldwork is the gap between the necessary support for Japanese language learning by candidates and the support given by the Japanese language teacher at the nursing care facility as a step toward the national examination. The analysis in this paper highlights the confusion of candidates who spend a few months at the facility after arriving and the limitation that the Japanese language teacher feels. Based on the views of actual members who are working at the care facility with candidates, this research aims at giving suggestions for practical support to candidates and the care site from the Japanese language teaching site.
著者
尾佐竹 猛
出版者
慶應義塾大学
雑誌
史学 (ISSN:03869334)
巻号頁・発行日
vol.13, no.3, pp.371-380, 1934-11
著者
斉藤 雅英
出版者
愛媛女子短期大学
雑誌
若手研究(B)
巻号頁・発行日
2003

1.PHA(後催眠健忘)暗示の潜在記憶への影響について検討することを目的として,催眠感受性検査中に提示された単語についてPHA暗示を与え,PHA解放前およびPHA解放後に単語完成課題をおこなわせた。PHA解放前のターゲット単語の単語完成率を比較すると,催眠感受性高群と低群との間で差は認められず,PHA暗示解放後のターゲット単語の単語完成率を比較しても,高群と低群との間に差は認められなかった。つまり,PHA暗示は,潜在記憶課題に影響しなかったと考えられる。この結果は,先行研究を支持する結果である。ただし,本実験の単語完成率をみると完成率は非常に低く,先行研究の未学習時の完成率と同レベルである。このことから,今回の実験結果は実験手続き上の問題によるプライミング効果の消失であるという解釈の可能性を否定できない。2.被暗示性の測度として状況的な欲求圧力による記憶の変容から被暗示性を測定することができるGSSを用い,被暗示性と催眠感受性との関連を検討することを目的とした。集団式催眠感受性検査(GTHS)とGSSの各得点の記述統計量および両者の相関関数を算出したところ,shiftのタイプII項目においてのみ催眠感受性との間に弱い正の相関が認められ,タイプIIの質問において反応が変遷する人ほど催眠感受性が高いという関連がみられた。しかしながら,GSSの他の得点は催眠感受性との関連は認められなかったことを鑑みれば,総じてGSSにおける被暗示性と催眠感受性は関連しないということが示されているという結論が得られた。3.基本的には記憶に依存している態度や性格について,催眠との関連を検討するためのツールを開発した。催眠が潜在記憶を外部から制御する手続であるととらえた場合,潜在的態度の変化を催眠の使用によりコントロールすることが可能と考えられる。このことから,Web版潜在連合システムにより,今後,催眠と催眠に対する潜在的態度との関連を検討することが可能となった。
著者
塚原 拓馬
出版者
実践女子大学
雑誌
実践女子大学生活科学部紀要 (ISSN:13413244)
巻号頁・発行日
no.51, pp.47-55, 2014-03

The present paper discusses characteristics of old age in the life cycle from a psychological perspective and examines successful aging and methods of support. First, validity of the "continuity theory" that explains successful aging from the perspective of personality theory inold age is reviewed. Next, "integration and despair," which are developmental tasks in old age are described from an existential perspective, and complexity of the process of "acceptance of death" is discussed. Furthermore, as typical developmental diseases, depressive disorders are focused on and the importance of psychosocial approach is discussed. Based on the fi ndings from above, it is suggested that practice of clinical developmental support and the community support dynamic system suitable for developmental characteristics in old age, which includes interpersonal relationships and the community are essential for providing support.
著者
田中 裕子
出版者
[出版者不明]
巻号頁・発行日
2013

制度:新 ; 報告番号:甲3882号 ; 学位の種類:博士(文学) ; 授与年月日:2013/2/25 ; 早大学位記番号:新6340
著者
山崎延吉 著
出版者
永東書店
巻号頁・発行日
1908
著者
八木 裕司
出版者
東京大学大学院工学系研究科 電子工学専攻
巻号頁・発行日
2007-03-22

報告番号: 甲22295 ; 学位授与年月日: 2007-03-22 ; 学位の種別: 課程博士 ; 学位の種類: 博士(工学) ; 学位記番号: 博工第6500号 ; 研究科・専攻: 工学系研究科電子工学専攻
著者
高橋 大希
巻号頁・発行日
2017-03-23

ⅲ, 73
著者
八ッ塚 一郎
出版者
日本社会心理学会
雑誌
社会心理学研究 (ISSN:09161503)
巻号頁・発行日
vol.29, no.3, pp.170-179, 2014-03-17 (Released:2017-02-28)

Changes in the usage of the verb "ijimeru" (to bully) and the noun "ijime" (bullying) in Japanese news-paper articles were investigated. Full-text searches and postpositional particle analysis were performed on issues of three major Japanese newspapers published between 1987 and 2011. The passive form of ijimeru (to bully) was used much more often than was the active form during the entire period investigated. During several specific years, the noun, ijime (bullying), appeared as a subject very frequently, but this trend was not consistent, and the number of articles containing this word decreased in most of the other years. Ijime (bullying)refers to an action that occurs independently of any particular actor. As such, it would be expected to appear frequently during any period of time. However, the word is construed to refer to suffering endured by an unlucky passive victim or to rare events such as natural disasters. The dissociation of the denotation from the actual usage of ijime (bullying) as well as the use of the term ijime (bullying) more generally are discussed from the perspective of social representations.