著者
森本 大二郎 井須 豊彦 金 景成 菅原 淳 濱内 祝嗣 下田 祐介 笹森 徹 松本 亮司 磯部 正則
出版者
日本脊髄外科学会
雑誌
脊髄外科 (ISSN:09146024)
巻号頁・発行日
vol.24, no.1, pp.6-11, 2010 (Released:2017-05-11)
参考文献数
22
被引用文献数
7 3

Objective : Sacroiliac joint (SIJ) dysfunction can produce lower back pain and referred symptoms in the buttocks, legs and groin. Approximately 3.5~30% of all lower back pain is associated with SIJ dysfunction. Recently, we have been treating more SIJ dysfunction cases due to the increasing incidence of lumbar degenerative disorder (LDD). Here we report our experience in treating 20 SIJ dysfunction patients.  Patients and methods : The study involved 20 SIJ dysfunction patients (5 male and 15 female) with a mean age of 67.6 years (range 35~81 years). SIJ dysfunction was diagnosed using the one finger test, modified Newton test and sacroiliac joint block. Patients initially underwent conservative treatment, including sacroiliac joint block, stabilization using pelvic belts and rehabilitation. Sixteen patients underwent surgery for LDD. The mean follow-up period was 4.1 months. The clinical outcomes were evaluated using the Japan Orthopedic Association Scale score (JOA score).  Results : All patients with SIJ dysfunction showed symptom improvement. In the group of the patients who underwent the LDD operation, the improvement score and recovery rate of treatments for SIJ dysfunction tended to be lower than for those without surgery for LDD. Fourteen patients (70%) had some referred symptoms in the leg and lower abdomen.  Conclusion : Our treatment of SIJ dysfunction resulted in good clinical outcomes. SIJ dysfunction should be considered a cause of lower back pain and a potential factor in failed back surgery. SIJ dysfunction should be considered when designing treatments for LDD.

4 0 0 0 OA 甲状腺疾患

著者
森 徹
出版者
一般社団法人 日本内科学会
雑誌
日本内科学会雑誌 (ISSN:00215384)
巻号頁・発行日
vol.86, no.7, pp.1109-1110, 1997-07-10 (Released:2008-06-12)
著者
柴田 愛子 曽山 典子 岡村 誠 森 徹
出版者
関西学院大学
雑誌
基盤研究(C)
巻号頁・発行日
1997

我々の研究は、法や規則やモラルに反した行為、例えば、いじめが行われている状態を考える。この違反行為を知りながら傍観する傍観者達の行動を進化的非協力ゲームとしてモデル化し、実験で検証した。この理論によれば傍観者が(1)いじめを報告する(2)報告しない(3)確率p^*で報告するの3つの状況はNash均衡である。しかし、3番目の均衡は進化的不安定な均衡(evolutionarily unstable equilibrium)である。そして、日本人大学生を対象とした8回の実験結果から、いじめを排除するサービスは公共財であり、傍観者の生徒からのいじめについての報告が増える条件は、(1)いじめを報告したときの費用(仕返し等)が小さい。(2)生徒がいじめを傍観することから受ける不効用が大きい(3)教師がいじめを取り上げるのに至る必要な最小報告生徒数が少ないことなどが判明した。しかし、最も重要な結論は、(4)クラスの規模が小さくなれば、協力的行動が増え傍観者が減る結果である。この結論は学校のクラスの小人数化政策を支持する。3回の国際学会で報告され、カルフォルニア大学のDaniel Friedmanとイエール大学のShyam Sunderが高く評価した。(論文は英文で投稿中)これらの結果が、日本人に特有なものか否かを調べる為に、現在までに3回の国際混合実験が行なわれた。実験1は関西学院大学(1998.9.24)で、日本とドイツの大学生10名ずつ、実験2はドイツAugsburg大学(1999.9.6)で、日本人大学生10名、ドイツ人大学生8名日本人留学生2名、実験3が天理大学(2000.11.8)で日本、中国、台湾の大学生を40人集めて実施された。その結果、事前協議効果は同国人と外国人に関係なく存在する。また、異なる国籍のメンバーが同一グループを形成する場合、信頼感が薄くなることが判明した。
著者
柴田 愛子 森 徹 曽山 典子 岡村 誠
出版者
公共選択学会
雑誌
公共選択の研究 (ISSN:02869624)
巻号頁・発行日
vol.2000, no.34, pp.43-59, 2000-06-25 (Released:2010-10-14)
参考文献数
18

Bullying in school is a serious problem in Japan as well as in most other countries. Bystanders rarely report instances of bullying to teachers, parents and other authorities. In this paper, we model bystander behavior by utilizing the theory of non-cooperative games, which assumes that bullying acts are stopped by a classroom teacher only when more than a certain number of students report the instances. Every bystander stands to gain from the resolution of bullying activity. But when a bystander reports this activity, she will have to deal with psychological and/or physical costs if the total number of reports falls below the required minimum. Under this structure of payoffs in our “bullying game” it can be shown that if all bystanders maximize their expected payoffs, there are two stable symmetric Nash equilibria. At one equilibrium, all bystanders report the instances of bullying to their teacher, and at the other equilibrium, no one reports. We conducted a series of experiments in which subjects played our “bullying game” under various values of parameters. The results of our experiments support the expected payoff-maximizing behavior of bystanders. Based on this verification of expected-payoff maximizing behavior through experiments, we develop guidelines for policies which could serve to increase reporting activity of bystanders and dissolve bullying activity. These include reducing the threshold number for reporting from students, increasing the disutility of students' observing bullying behavior, mitigating the psychological and/or physical costs for the reporting of bullying, and scale down of class size. The effectiveness of each policy is then analyzed theoretically and compared with the other alternatives.
著者
石附 将武 高橋 翔 萩原 亨 石井 啓太 岩﨑 悠志 森 徹平 花塚 泰史
出版者
公益社団法人 土木学会
雑誌
AI・データサイエンス論文集 (ISSN:24359262)
巻号頁・発行日
vol.3, no.J2, pp.642-649, 2022 (Released:2022-11-12)
参考文献数
17

本論文では,複数の車載センサーのデータを統合して冬期の路面状態を推定する手法を提案する.提案手法は,カメラとタイヤ内加速度センサー,路面温度計,マイクのそれぞれから路面状態を推定する複数の識別器に加え,それらの出力である路面状態確率をLate Fusionするマルチモーダルモデルである.推定する路面は道路管理において使用されている乾燥,半湿,湿潤,シャーベット,凍結,積雪の6路面である.提案手法は冬期の一般道で実車から得るデータを用いた実験によって,その有効性が確認された.
著者
山森 徹雄 植原 典子 清野 和夫 谷 信幸 島崎 政人 高橋 秀美 中原 元 斉藤 彰久 浅井 政一 長山 克也
出版者
社団法人 日本補綴歯科学会
雑誌
日本補綴歯科学会雑誌 (ISSN:03895386)
巻号頁・発行日
vol.40, no.2, pp.245-248, 1996-04-01 (Released:2010-08-10)
参考文献数
11
被引用文献数
1 2

It was attempted to apply barrel finishing to improve the surface texture of the basal surface of the complete denture. The effect of barrel finishing on the denture base resin of rough surface should be confirmed to understand the alteration of the basal surface of complete denture after barrel finishing, because it is corrugated. The denture base resin samples with standardized corrugated surface were made using a metal mold, then each sample was divided into halves. One of the halves was barrel finished following the manufacturer's instruction after masking the datum plane, whereas the other one was used as a control without finishing. Both samples were observed under the reading microscope, and the distances between the base line and the top of each corrugation or the bottom of each corrugation were measured. Observation under the scanning electron microscope was also made. The results were as follows:1. The scanning electron microscopic observations showed that the top of the corrugation was obviously made round and smooth by barrel finishing, and that the bottom of the corrugation was also made smooth but it was less smooth than the top of the corrugation.2. The cutting depth of the denture base resin was 218.13μm at the top and 3.53μm at the bottom of the corrugation.These findings suggest that there is no problem after barrel finishing of the basal surface of complete dentures even if attention was paid to the height of the bead established for the posterior palatal seal.
著者
荒木田 安弘 山森 徹雄 アラキダ ヤスヒロ ヤマモリ テツオ Yasuhiro ARAKIDA Tetsuo YAMAMORI
雑誌
奥羽大学歯学誌
巻号頁・発行日
vol.34, no.4, pp.137-144, 2007-12

Histatin-5 and the basic Proline-rich peptide P-E (PRP-PE) have been revealed as candidates of bitter binding proteins. However, it has not been confirmed whether these compounds were carriers of or blockers to bitter taste so far. On the other hand, it has been reported that psychical stress reduced the sensitivity of bitterness. The present study was carried out to measure the clinical concentrations of Histatin-5 and PRP-PE in saliva under the mental stress. Stimulated parotid saliva was obtained from the parotid glands of 10 healthy adult subjects before and after the load of stress of the Kraepelin psycho-diagnostic test with a loud noise (5,000Hz, 100dB) for 30 mins. The salivary cortisol concentration and the LF/HF ratio on ECG were adopted as indices of sympathetic nervous activity to check a liability for the load of stress. The concentrations of Histatin-5 and PRP-PE in saliva were quantified by ELISA test. A significant increase in the salivary cortisol after the stress was recognized in half of the subjects, among which an increase of LF/HF ratio was also observed. Histatin-5 in the parotid saliva was significantly reduced by the stress in this group, but PRP-PE was not. These findings suggest that Histatin-5 in saliva might be a carrier protein of bitter substances, but a function of PRP-PE was not clear in this study.
著者
野崎 由美 三森 徹 中嶌 圭 岩尾 憲明 山本 健夫 西山 真由美 中澤 正樹 小松 則夫 桐戸 敬太
出版者
山梨大学医学会
雑誌
山梨医科学雑誌 = 山梨医科学雑誌 (ISSN:13485091)
巻号頁・発行日
vol.26, no.1, pp.23-28, 2013

症例は67歳,女性。発熱と頸部リンパ節腫脹を認め,他院に入院した。入院後,肝機能障害の増悪と血小板減少の進行,さらに末梢血中への異常細胞の出現を認めた。頸部リンパ節生検後にステロイドパルス療法を開始したが,意識障害と呼吸状態の悪化を認め,当院に転院した。転院時,pH7.238,乳酸値15.9 mmol/? と高度の乳酸アシドーシスを認めた。転院後の第3病日に右脳内出血を併発し,第9病日に永眠された。経過中,リンパ節生検結果よりびまん性大細胞型B細胞性リンパ腫(DLBCL)と診断した。重篤な乳酸アシドーシスを伴った原因としては,腫瘍細胞からの乳酸産生の亢進や,剖検により確認された腫瘍細胞の肝浸潤による肝機能障害からの代謝の遅延などが想定された。悪性リンパ腫の経過中に乳酸アシドーシスを合併した症例の報告例は極めて少なく,予後不良であるが,その要因および治療に関して文献的な考察を加えて報告する。
著者
松香 芳三 萩原 芳幸 玉置 勝司 竹内 久裕 藤澤 政紀 小野 高裕 築山 能大 永尾 寛 津賀 一弘 會田 英紀 近藤 尚知 笛木 賢治 塚崎 弘明 石橋 寛二 藤井 重壽 平井 敏博 佐々木 啓一 矢谷 博文 五十嵐 順正 佐藤 裕二 市川 哲雄 松村 英雄 山森 徹雄 窪木 拓男 馬場 一美 古谷野 潔
出版者
公益社団法人 日本補綴歯科学会
雑誌
日本補綴歯科学会誌 (ISSN:18834426)
巻号頁・発行日
vol.5, no.3, pp.281-290, 2013 (Released:2013-11-06)
参考文献数
3
被引用文献数
2 1

目的:(社)日本補綴歯科学会は病態とその発現機序の把握に基づく適切な補綴歯科治療を国民に提供するために,補綴歯科治療における新たな病名システムを提案した.これは患者に生じている「障害」を病名の基本とし,この障害を引き起こしている「要因」を併記して病名システムとするものであり,「A(要因)によるB(障害)」を病名システムの基本的な表現法としている.本研究の目的は考案した方法に従って決定した補綴歯科治療における病名の信頼性と妥当性を検討することである.方法:模擬患者カルテを作成し,(社)日本補綴歯科学会診療ガイドライン委員会で模範解答としての病名(以下,模範病名)を決定した.その後,合計50 名の評価者(日本補綴歯科学会専門医(以下,補綴歯科専門医)ならびに大学病院研修歯科医(以下,研修医))に診断をしてもらい,評価者間における病名の一致度(信頼性)ならびに(社)日本補綴歯科学会診療ガイドライン委員会による模範病名との一致度(妥当性)を検討した.結果:評価者間の一致度を検討するための算出したKrippendorff’s αは全体では0.378,補綴歯科専門医では0.370,研修医では0.401 であった.Krippendorff’s αは模範病名との一致度の高い上位10 名の評価者(補綴歯科専門医:3 名,研修医:7 名)では0.524,上位2 名の評価者(補綴歯科専門医:1 名,研修医:1 名)では0.648 と上昇した.日常的に頻繁に遭遇する病名に関しては模範病名との一致度が高かったが,日常的に遭遇しない病名は模範病名との一致度は低い状況であった.さらに,模範病名との一致度とアンケート回答時間や診療経験年数の関連性を検討したところ,相関関係はみられなかった.結論:全評価者間の一致度を指標とした本病名システムの信頼性は高くはなかったが,模範病名との一致度の高い評価者間では一致度が高かった.日常的に遭遇する補綴関連病名については模範病名との一致度が高かった.以上から(公社)日本補綴歯科学会の新しい病名システムは臨床上十分な信頼性と妥当性を有することが示唆された.
著者
島崎 伸子 山森 徹雄 小笠原 綾子 川田 毅 沖野 憲司 塩山 司 石橋 寛二 佐藤 匡
出版者
Japanese Society of Psychosomatic Dentistry
雑誌
日本歯科心身医学会雑誌 (ISSN:09136681)
巻号頁・発行日
vol.8, no.1, pp.37-44, 1993-06-25 (Released:2011-09-20)
参考文献数
15

Recently, many cases in which stress is the main cause of craniomandibular disorder (CMD) have been reported. Thus, in order to properly diagnose and treat the different stages of CMD, it becomes vitally important to objectively grasp the effect of stress.This report studied the changes in salivary pH of 15 normal adults with no CMD or autonomic nervous system (ANS) abnormalities. Stress was applied experimentally by having the subject perform and answer simple factorial equations under conditions of heavy lighting and sound for a period of 1 minute. Mixed resting saliva was collected before and after such stress was applied, and additional physiological parameters such as the pneumogram, electrocardiogram, and plethysmogram were also recorded to determine the state of the ANS. The saliva samples were obtained by sampling paper during the resting period before stress, immediately after stress, as well as at the 3, 6 and 10 minute marks. Furthermore, the saliva measurements were taken 9 minutes more for each time frame. The samples were covered with a plastic plate and the pH was measured. Measurements showed the pH value to stabilize after 1 minute. However, after removing the plastic plate and allowing volatization of CO2 gas, the pH began to elevate until it reached a maximum peak at approximately 5 minutes. This pH difference from the stable state was referred to as DIAL. Analyses concerning ANS were also recorded for 1 minute before collecting the saliva.In conclusion, the coefficiency of the plethysmogram amplitude increased due to slight stress, while stable pH ualues and DpH1 decreased after slight stress, thus indicating a relationship between the activity of the parameters involving autonomic responses and pH curve of the saliva. We concluded that these studies showed that stable pH values and DpH1 reflect the activity of the autonomic nerve responses.
著者
古森 徹哉 瀬戸口 信郎 川崎 敏男
出版者
天然有機化合物討論会実行委員会
雑誌
天然有機化合物討論会講演要旨集 10 (ISSN:24331856)
巻号頁・発行日
pp.216-223, 1966-09-15 (Released:2017-08-18)

The unknown, nonsteroidal, nonglycosidal and N-free substance, which had been obtained as crystals from the root tubers of Dioscorea bulbifera L. forma spontanea Makino et Nemoto, was found to be a mixture of at least three compounds. One of them, named bulbiferin C, m.p.255°, (α)_D +17.3°, was isolated only in trace and the structures of major component, bulbiferin B, m.p. 285°, (α)_D+103.0° and minor, bulbiferin A, m.p. 283°, (α)_D +16.2°, were investigated. Bulbiferin B, C_<19>H_<20>O_6, m.w. 344 (mass) has γ-lactone, β-substituted furane and no hydroxyl groups (positive Ehrlich reaction, I.R., U.V. and mass spectra). B is converted to A by hydrolysis with NaOH in pyridine followed by neutralisation and methylation with diazometane. Bulbiferin A,C_<20>H_<24>O_7, m.w. 376 (mass), has hydroxyl, ester, γ-lactone and β-substituted furane functions (Ehrlich reaction, I.R., U.V. and mass spectra). On treatment with NaBH_4 B is unchanged but by catalytic hydrogenation over PtO_2 it gives a hexahydro-compound having tertiary hydroxyl group indicating B (and also A) has an ether oxygen. The hydrogenated B is reduced with LiAlH_4 and the product is subjected to the Se-dehydrogenation to give 1,2,5-trimethyl naphthalene. The N.M.R. spectra of tetrahydro-B and -A indicate the presence of one tertiary methyl group. From these and other experimental data B and A are respectively assigned the partial formulae (a) and (b) of furano-norditerpene type. The results of a further investigation on the location of the functional groups which lead to the tentative structures of B and A are presented.
著者
古森 徹哉 瀬戸口 信郎 川崎 敏男
出版者
天然有機化合物討論会実行委員会
雑誌
天然有機化合物討論会講演要旨集
巻号頁・発行日
vol.10, pp.216-223, 1966

The unknown, nonsteroidal, nonglycosidal and N-free substance, which had been obtained as crystals from the root tubers of Dioscorea bulbifera L. forma spontanea Makino et Nemoto, was found to be a mixture of at least three compounds. One of them, named bulbiferin C, m.p.255°, (α)_D +17.3°, was isolated only in trace and the structures of major component, bulbiferin B, m.p. 285°, (α)_D+103.0° and minor, bulbiferin A, m.p. 283°, (α)_D +16.2°, were investigated. Bulbiferin B, C_<19>H_<20>O_6, m.w. 344 (mass) has γ-lactone, β-substituted furane and no hydroxyl groups (positive Ehrlich reaction, I.R., U.V. and mass spectra). B is converted to A by hydrolysis with NaOH in pyridine followed by neutralisation and methylation with diazometane. Bulbiferin A,C_<20>H_<24>O_7, m.w. 376 (mass), has hydroxyl, ester, γ-lactone and β-substituted furane functions (Ehrlich reaction, I.R., U.V. and mass spectra). On treatment with NaBH_4 B is unchanged but by catalytic hydrogenation over PtO_2 it gives a hexahydro-compound having tertiary hydroxyl group indicating B (and also A) has an ether oxygen. The hydrogenated B is reduced with LiAlH_4 and the product is subjected to the Se-dehydrogenation to give 1,2,5-trimethyl naphthalene. The N.M.R. spectra of tetrahydro-B and -A indicate the presence of one tertiary methyl group. From these and other experimental data B and A are respectively assigned the partial formulae (a) and (b) of furano-norditerpene type. The results of a further investigation on the location of the functional groups which lead to the tentative structures of B and A are presented.
著者
森 徹 三砂 範幸 成澤 寛 茂木 幹義 長谷川 英男 宮田 彬
出版者
日本皮膚科学会西部支部
雑誌
西日本皮膚科 (ISSN:03869784)
巻号頁・発行日
vol.64, no.1, pp.55-57, 2002-02-01 (Released:2010-09-02)
参考文献数
12
被引用文献数
3 1

69歳,男性。初診の約1年前より左側膝窩部に自覚症状のない皮下腫瘤が出現しているのに気付いた。1年後,左下腹部に同様の腫瘤が出現したが,これは膝窩部から移動したものと患者は訴えた。山水の飲水歴はあったが,明らかな生食の既往はなかった。初診時,左下腹部に2ヵ所,左鼠径部に1ヵ所,弾性軟の腫瘤を触知した。3ヵ所の腫瘤をすべて摘出したところ,各々から虫体が検出された。虫体の肉眼所見および組織所見よりマンソン裂頭条虫の幼虫であるプレロセルコイドと同定し,マンソン孤虫症と診断した。通常,多くのマンソン孤虫症は単発例であるが,自験例はその後,右下肢にも虫体を認めており,計4匹の多発例であった。
著者
杉山 重夫 本田 昌徳 古森 徹哉
出版者
天然有機化合物討論会実行委員会
雑誌
天然有機化合物討論会講演要旨集
巻号頁・発行日
vol.31, pp.22-29, 1989

In our study on the isolation and structure elucidation of biologically active compounds from marine invertebrates, we synthesized the four diastereomers of C_<16>-phytosphingosine (10, 12, 25, and 26), acanthacerebroside A (1), and D-galactosylceramide (3b) as described below. (2S, 3S)-Allylic alcohol, which was prepared from the L-serine derivative and the (E)-vinylalane compound, was converted into (2S, 3S, 4R)- and (2S, 3S, 4S)-phytosphingosines by epoxidation, DIBAH reduction, and debenzylation. The same treatment of (2S, 3R)-allylic alcohol gave (2S, 3R, 4R)- and (2S, 3R, 4S)-phytosphingosines. (2R)-Acetoxytetracosanoic acid was prepared and coupled to (2S, 3S, 4R)-phytosphingosine to give the ceramide (34). Glycosylation of 34 gave the desired monoglycoside (36) and the bisglycoside (37). 36 was converted into 1 by deacetylation. New D-galactosylceramides were isolated from Chondropsis sp., but the absolute stereochemistry has not been determined. Therefore, (2S, 3S, 4R, 6E)- and (2R, 3R, 4R, 6E)-phytosphingosines were prepared via asymmetric epoxidation. The former was transformed to (2S, 3S, 4R, 6E, 2'R)-D-galactosylceramide and its heptaacetate. The spectral data of them were in excellent agreement with those of the natural specimens.
著者
本田 昌徳 上田 義隆 杉山 重夫 古森 徹哉
出版者
The Pharmaceutical Society of Japan
雑誌
Chemical and Pharmaceutical Bulletin (ISSN:00092363)
巻号頁・発行日
vol.39, no.6, pp.1385-1391, 1991-06-25 (Released:2008-03-31)
参考文献数
24
被引用文献数
12 20

A cerebroside, 1-O-(β-D-galactopyranosyloxy)-(2S, 3S, 4R, 6E)-2-[(R)-2-hydroxytetracosanoylamino]-17-methyl-6-octadecene-3, 4-diol (2), was asymmetrically synthesized from isobutyraldehyde. On the basis of a comparison of the physical data, the absolute structure of a new cerebroside 1b from a Chondropsis sp. sponge is thought to be the same at that of 2.
著者
大貫 武司 山森 徹雄
出版者
奥羽大学
雑誌
奥羽大学歯学誌 (ISSN:09162313)
巻号頁・発行日
vol.34, no.4, pp.145-152, 2007-12

Asymmetric arrangement of artificial teeth with the natural dentition adversely affects articulation, in which the difference between of right and left configurations in the dental arch exerts a functional influence on the contact between a tongue and palate.A previous study showed that 4-5mm bilaterally constricted inner arrangement of upper molar teeth led to the habituation of sound production with particular monosyllables right after the set-up of constricted appliance.By contrast, in this study ,the effect of the unilaterally constricted arrangement of artificial teeth on articulation was examined on the analysis of the time duration of consonant sounds in certain monosyllables. Five monosyllables /ki/, /shi/, /zi/, /chi/, /pi/ were examined with Computer Speech Labo〓. The results were as follows 1. The effect of the unilaterally constricted arrangement appeared in monosyllables /ki/, /shi/, /zi/, /chi/. 2. The time duration of the consonant sounds were extended in 3-5 days after the placement of the artificially constricted appliance. 3. The time duration of consonant sound in /ki/, /shi/, /chi/ reverted to the value before the placement of the appliance in 7-14 days. 4. The extended time duration of consonant sound in /zi/ was still observed 14 days after the placement of the appliance with the constriction of 4 mm or more. These results indicated that the unilaterally constricted arrangement of artificial teeth affected the articulation on alveolars and palatals with the succeeding vowel /i/.