著者
Michelle B. CHRISTENSEN Rebecca LANGHORN Amelia GODDARD Eva B. ANDREASEN Elena MOLDAL Asta TVARIJONAVICIUTE Jolle KIRPENTEIJN Sabrina JAKOBSEN Frida PERSSON Mads KJELGAARD-HANSEN
出版者
JAPANESE SOCIETY OF VETERINARY SCIENCE
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
vol.75, no.4, pp.459-466, 2013 (Released:2013-05-02)
参考文献数
28
被引用文献数
4 8

Canine serum amyloid A (SAA) is a useful diagnostic marker of systemic inflammation. A latex agglutination turbidimetric immunoassay (LAT) was validated for automated measurements. The aim of the study was to evaluate the clinical applicability of SAA measured by the LAT. SAA was measured in 7 groups of dogs with and without systemic inflammation (n=247). Overlap performance was investigated. Diagnostic performance was compared to body temperature and leukocyte markers. Clinical decision limits for SAA were estimated. In dogs with neurological, neoplastic or gastrointestinal disorders (n=143), it was investigated whether a higher proportion of SAA positive dogs could be detected in cases of complications with risk of systemic inflammation. Significantly higher concentrations of SAA were measured in dogs with (range [48.75; 5,032 mg/l]), compared to dogs without systemic inflammation [0; 56.4 mg/l]. SAA was a more sensitive and specific marker of systemic inflammation (area under the receiver-operating characteristic curve (AUC) 1.00), compared to body temperature (0.6) and segmented neutrophils (best performing leukocyte marker, 0.84). A clinical decision limit of 56.4 mg/l was established giving close to perfect discrimination between dogs with and without systemic inflammation. Higher proportions of SAA-positive dogs were observed in dogs with neurological, neoplastic and gastrointestinal disorders with complications known to increase risk of systemic inflammation, compared to uncomplicated cases. The automated LAT makes SAA applicable as a relevant diagnostic marker of systemic inflammation in dogs for routine random-access real-time use in a general clinical setting.
著者
Jooyeon Ko Ji-Hea Woo Jin-Gang Her
出版者
The Society of Physical Therapy Science
雑誌
Journal of Physical Therapy Science (ISSN:09155287)
巻号頁・発行日
vol.23, no.2, pp.255-258, 2011 (Released:2011-06-24)
参考文献数
22
被引用文献数
14 28

[Purpose] To determine inter-rater and intra-rater reliability using video recordings, and the concurrent validity of the Gross Motor Function Classification System (GMFCS). [Subjects] The subjects who were assessed were 71 children with cerebral palsy (CP; 46 boys, 25 girls) who were divided into three age groups according to the GMFCS guidelines; 0-2 years, 2-4 years, and 4-6 years. [Methods] Eleven pediatric physical therapists rated 71 video recordings of children with CP to test inter-rater reliability. Two of them rescored the same video recordings to test intra-rater reliability at an interval of one month. Concurrent validity was evaluated by comparing GMFCS levels with the subscale of the Pediatric Evaluation of Disability Inventory (PEDI) such as self-care, mobility, and social ability. [Results] By age group, inter-rater reliability was high (ICC = 0.994, 0.993, and 0.996 respectively). Intra-rater reliability was also high (ICC = 0.972-0.996), and correlation was higher between GMFCS level and the mobility domain of PEDI than between GMFCS level and non-motor domains of PEDI. [Conclusion] This study confirmed the reliability and validity of the GMFCS, supporting its use in clinical practice and research.
著者
野尻 美保子 清水 康弘 CHEN Chuan-ren SHU Jing
出版者
大学共同利用機関法人高エネルギー加速器研究機構
雑誌
基盤研究(C)
巻号頁・発行日
2010

LHC におけるハードプロセスに伴うジェットや、重い粒子の崩壊からくるジェットの内部構造など、 QCD プロセスに関わる性質に着目し、 LHC での新粒子の発見を確実にする方法を提案した。 特に縮退した新粒子を LHC で発見するために 制動放出を利用する方法や、ジェットの部分構造を利用して,トップの偏極を測定する方法を開発した。またこの方法をもちいて、スカラートップの混合の測定や、暗黒物質の探索可能性について解析をおこなった。
著者
Lei Zhongfang Wu Ting Zhang Yi Liu Xiang Wan Chunli Lee Duu-Jong Tay Joo-Hwa
出版者
Elsevier Ltd.
雑誌
Bioresource technology (ISSN:09608524)
巻号頁・発行日
vol.128, pp.774-778, 2013-01
被引用文献数
15 1

Soil infiltration treatment (SIT) is ineffective to treat ammonium wastewaters of total nitrogen (TN) > 100 mg l−1. This study applied a novel two-stage SIT process for effective TN removal from wastewaters of TN > 100 mg l−1 and of chemical oxygen demand (COD)/TN ratio of 3.2–8.6. The wastewater was first fed into the soil column (stage 1) at hydraulic loading rate (HLR) of 0.06 m3 m−2 d−1 for COD removal and total phosphorus (TP) immobilization. Then the effluent from stage 1 was fed individually into four soil columns (stage 2) at 0.02 m3 m−2 d−1 of HLR with different proportions of raw wastewater as additional carbon source. Over the one-year field test, balanced nitrification and denitrification in the two-stage SIT revealed excellent TN removal (>90%) from the tested wastewaters.
著者
Shivaram Niranjan Timmers Henry Tong Xiao-Min Sandhu Arvinder
出版者
Elsevier B.V.
雑誌
Chemical physics (ISSN:03010104)
巻号頁・発行日
vol.414, pp.139-148, 2013-03
被引用文献数
7

We present experimental results and a theoretical framework for understanding the ionization dynamics in atoms exposed to XUV attosecond pulse trains and strong multi-cycle infrared (IR) fields. We invoke the Floquet formalism to model dressed atomic states as a manifold of Fourier components spaced by the laser frequency. In XUV-IR pump–probe measurements, we observe that the ionization yield oscillates due to quantum interference between photo-excitation paths to a Floquet state. We show that the intensity-dependent shifts of atomic structure modify the ionization channels and the associated interference phase. We extract this phase variation and compare it with simulations. These results provide a comprehensive description of the two-color ionization process and enable new schemes for control of attosecond ionization and fragmentation dynamics.
著者
Ki-Ja LEE Miori KISHIMOTO Junichiro SHIMIZU Yoshiyasu KOBAYASHI Kotaro MATSUMOTO Naoki SASAKI Mitsuo ISHII Hisashi INOKUMA Toshiroh IWASAKI Yoh-Ichi MIYAKE Kazutaka YAMADA
出版者
公益社団法人 日本獣医学会
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
vol.73, no.1, pp.113-115, 2011 (Released:2011-01-29)
参考文献数
8
被引用文献数
2 10

We report here the non-contrast and contrast-enhanced computed tomography performed in two calves with brain abscess and multiple pulmonary abscesses with pharyngeal abscess, respectively. Contrast-enhanced computed tomography was useful in the diagnosis of these diseases in both calves. The diseases were confirmed by histopathological examination.
著者
Ryozo Nagai Koichiro Kinugawa Hiroshi Inoue Hirotsugu Atarashi Yoshihiko Seino Takeshi Yamashita Wataru Shimizu Takeshi Aiba Masafumi Kitakaze Atsuhiro Sakamoto Takanori Ikeda Yasushi Imai Takashi Daimon Katsuhiro Fujino Tetsuji Nagano Tatsuaki Okamura Masatsugu Hori the J-Land Investigators
出版者
日本循環器学会
雑誌
Circulation Journal (ISSN:13469843)
巻号頁・発行日
vol.77, no.4, pp.908-916, 2013 (Released:2013-03-25)
参考文献数
24
被引用文献数
21 93

Background: A rapid heart rate (HR) during atrial fibrillation (AF) and atrial flutter (AFL) in left ventricular (LV) dysfunction often impairs cardiac performance. The J-Land study was conducted to compare the efficacy and safety of landiolol, an ultra-short-acting β-blocker, with those of digoxin for swift control of tachycardia in AF/AFL in patients with LV dysfunction. Methods and Results: The 200 patients with AF/AFL, HR ≥120beats/min, and LV ejection fraction 25–50% were randomized to receive either landiolol (n=93) or digoxin (n=107). Successful HR control was defined as ≥20% reduction in HR together with HR <110beats/min at 2h after starting intravenous administration of landiolol or digoxin. The dose of landiolol was adjusted in the range of 1–10μg·kg–1·min–1 according to the patient’s condition. The mean HR at baseline was 138.2±15.7 and 138.0±15.0beats/min in the landiolol and digoxin groups, respectively. Successful HR control was achieved in 48.0% of patients treated with landiolol and in 13.9% of patients treated with digoxin (P<0.0001). Serious adverse events were reported in 2 and 3 patients in each group, respectively. Conclusions: Landiolol was more effective for controlling rapid HR than digoxin in AF/AFL patients with LV dysfunction, and could be considered as a therapeutic option in this clinical setting.  (Circ J 2013; 77: 908–916)
著者
Wei-Hsi Chen Tzu-Hui Li Lian-Hui Lee Chih-Cheng Huang
出版者
一般社団法人 日本内科学会
雑誌
Internal Medicine (ISSN:09182918)
巻号頁・発行日
vol.51, no.17, pp.2439-2441, 2012 (Released:2012-09-01)
参考文献数
11
被引用文献数
4 17

A nummular headache (NH) is a type of primary headache that results from cranial neuralgia without a known cause. We herein report the case of a woman who suffered two episodes of focal headache in the left parietal area with identical characteristics that were compatible with NH. During the recovery phase of the second NH episode, the pain resurged with shingles coinciding with the painful area. The patient's NH subsided in parallel with resolution of the shingles. These findings support a diagnosis of peripheral neuralgia with NH. Latent virus infections, such as Varicella-zoster virus, that frequently cause distal nerve damage in patients with zoster sine herpete may be associated with epicranial neuralgia and NH.
著者
Seiji KAWAMOTO Mitsuoki KANEOKE Kayo OHKOUCHI Yuichi AMANO Yuki TAKAOKA Kazunori KUME Tsunehiro AKI Susumu YAMASHITA Ken-ichi WATANABE Motoni KADOWAKI Dai HIRATA Kazuhisa ONO
出版者
(社)日本農芸化学会
雑誌
Bioscience, Biotechnology, and Biochemistry (ISSN:09168451)
巻号頁・発行日
vol.75, no.1, pp.140-144, 2011-01-23 (Released:2011-01-23)
参考文献数
15
被引用文献数
22

We tested the effect of oral administration of fermented sake lees with lactic acid bacteria (FESLAB) on a murine model of allergic rhinitis upon immunization and nasal sensitization with ovalbumin (OVA). We used Lactobacillus paracasei NPSRIk-4 (isolated from sake lees), and L. brevis NPSRIv-8 (from fermented milk) as starter strains to produce the FESLAB. Oral FESLAB administration resulted in the development of significantly fewer sneezing symptoms than those seen in sham control animals given sterile water. We also found that FESLAB suppressed the allergen-induced degranulation of RBL2H3 rat basophilic leukemia cells.
著者
林 泉忠 Lim Chuan-tiong
出版者
林泉忠
巻号頁・発行日
2010-04

平成17年度~平成19年度科学研究費補助金(基盤研究(B)(海外))研究成果報告書 研究概要:(平成19年度時点)19年度は、本研究プロジェクト「『辺境東アジア』住民のアイデンティティをめぐる国際比較調査研究」の3年目で、予定通り、沖縄での調査をはじめ、台湾政治大学と香港大学の協力を得て、11月に沖縄、台湾、香港、そしてマカオにおいて電話による同時アンケート調査を順調に実施した。過去2年間の質問を踏襲した上で、四地域それぞれの特性を考慮し地元に関する質問を大幅に増やした。調査は、文化的・民族的帰属意識と政治的・国家的帰属意識と大きく二つのカテゴリーに分類して行った。調査結果に関しては、過去2年間のそれに比べ、四地域それぞれ若干の変化が見られると同時に、アイデンティティ構造は四地域共に比較的に安定していることが調査から分かった。すなわち、エスニック・アイデンティティに関する質問群の回答結果から、地元意識の強い順は、台湾・沖縄・香港・マカオとなり、またナショナル・アイデンティティについて、国・中央政府への求心力の強い順は、マカオ・沖縄・香港・台湾になっている。とりわけ、若者の政治的自立志向に関して、台湾は最も強く、最も弱いマカオや沖縄と対照的な結果になった。 3年目の調査結果の一部はすでに11月27日に沖縄県庁にある記者クラブで開かれた記者会見で公表し、台湾と香港の協力機関もそれぞれ現地のマスコミに報告した。沖縄では、沖縄タイムス、琉球新報、RBC(TBS)ラジオ放送、RBCテレビ放送の取材も受けた。また、学術報告に関しては、アジア政経学会、青山学院大学国際研究センター、JICA移民資料館、台湾政治学会、WAPOR Regional Seminar(インド)、北京大学、南開大学(天津)、復旦大学(上海)、上海師範大学などで、調査で得た知見に基づき、研究発表を行った。さらに、三年間の研究成果として報告書をまとめ、「辺境東アジア」地域のダイナミックなアイデンティティ・ポリティクスを呈示している。 未公開:P.25以降(別刷論文のため)
著者
Miwa Yamaguchi Kokichi Arisawa Hirokazu Uemura Sakurako Katsuura-Kamano Hidenobu Takami Fusakazu Sawachika Mariko Nakamoto Tomoya Juta Eisaku Toda Kei Mori Manabu Hasegawa Masaharu Tanto Masayuki Shima Yoshio Sumiyoshi Kenji Morinaga Kazunori Kodama Takaichiro Suzuki Masaki Nagai Hiroshi Satoh
出版者
(公社)日本産業衛生学会
雑誌
Journal of Occupational Health (ISSN:13419145)
巻号頁・発行日
pp.12-0264-OA, (Released:2013-04-09)
被引用文献数
11 54

Objective: Perfluorooctanesulfonate (PFOS) and perfluorooctanoate (PFOA) have been shown to accumulate in the human body. The purpose of the present study was to examine the factors associated with the blood levels of PFOS and PFOA. Methods: A cross-sectional study was performed on 307 men and 301 women (aged 16-76 years) living in 15 prefectures in Japan. Blood levels of PFOS and PFOA were measured by liquid chromatography-mass spectrometry. Hepatic enzymes (γ-GTP, GOT, and GPT) and ω-3 polyunsaturated fatty acids (DHA and EPA) levels in serum were also measured. Associations between the levels of PFOS and PFOA in blood and the intake frequency of 41 kinds of dishes, foods and beverages and the serum levels of liver enzymes and ω-3 polyunsaturated fatty acids were examined using rank correlations. Results: Frequency of intake of boiled fish in broth, sliced raw fish and coastal fish showed significant positive correlations with PFOS concentrations in blood after adjustments for potential confounders. Serum levels of GOT, GPT, DHA and EPA showed significant positive correlations with PFOS and PFOA in blood. There was also a significant regional difference in the blood levels of PFOS and PFOA, with medians being highest in the Tokai/Hokuriku/Kinki region. Conclusion: These findings suggest that the concentrations of PFOS in blood were mainly associated with fish consumption and that the levels of PFOS and PFOA were mainly associated with the serum levels of liver enzymes in Japanese populations. Further investigations are required to clarify the reason for the regional differences in blood levels of PFOS and PFOA in Japan.
著者
Hui-Fen Chiu Brian K. Chen Chun-Yuh Yang
出版者
日本疫学会
雑誌
Journal of Epidemiology (ISSN:09175040)
巻号頁・発行日
pp.JE20120155, (Released:2013-04-01)
参考文献数
22
被引用文献数
5 16

Background: In this cohort study, we investigated whether a diagnosis of herpes zoster (HZ) was associated with a higher risk of subsequent cancer as compared with the Taiwanese general population.Methods: Data were obtained from the Taiwan National Health Insurance Research Database. In total, 38 743 patients who were aged 50 years or older and had received ambulatory care for HZ between 1997 and 2006 were identified as the study cohort; 116 229 age- and sex-matched patients without HZ were included as the comparison cohort. We used Cox proportional hazards regression models to estimate the hazard ratios (HRs) for subsequent cancer, after controlling for potential confounders.Results: The HR for subsequent cancer varied according to time since HZ diagnosis. The HR was 1.58 (95% CI, 1.38–1.80) within the first year, 1.30 (95% CI, 1.15–1.46) between 1 and 2 years, 1.10 (95% CI, 0.98–1.24) between 2 and 3 years, 1.02 (95% CI, 0.91–1.15) between 3 and 4 years, and 1.08 (95% CI, 0.96–1.21) between 4 and 5 years. The risk of subsequent cancer, particularly lung cancer, was significantly higher during the first 2 years after initial diagnosis of HZ.Conclusions: Our findings suggest that an HZ diagnosis is a marker of occult malignancy, particularly in lung cancer. The HRs for cancer decreased gradually over time and were no longer significant after 2 years of follow-up, which indicates that the association between HZ and cancer is likely due to detection bias.
著者
Ryuji FUKUSHIMA Rieko YOSHIYUKI Noboru MACHIDA Hirotaka MATSUMOTO Soomin KIM Lina HAMABE Hsu HUAI-CHE Toshiharu FUKAYAMA Shuji SUZUKI Derya AYTEMIZ Ryo TANAKA Yoshihisa YAMANE
出版者
公益社団法人 日本獣医学会
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
pp.12-0319, (Released:2013-04-05)
被引用文献数
1 5

A four-month-old female Labrador retriever was brought to the Tokyo University of Agriculture and Technology Animal Medical Center for examination of its main symptoms of cough, tachypnea and exercise intolerance. Upon examination, the dog was found to have cyanosis and inadequate growth. Echocardiography revealed tetralogy of Fallot. Cardiac catheterization confirmed that the main pulmonary artery was completely occluded and that blood flowed from the aorta to the pulmonary artery. Accordingly, the animal was diagnosed with extreme tetralogy of Fallot.
著者
Lina WAKAKO Yo-ichi MATSUMOTO Hiroyuki KANAI Toyonori NISHIMATSU Hirokazu KIMURA Hideo MOROOKA
出版者
一般社団法人 日本繊維機械学会
雑誌
Journal of Textile Engineering (ISSN:13468235)
巻号頁・発行日
vol.54, no.2, pp.33-39, 2008-04-15 (Released:2008-07-08)
参考文献数
19

To examine the aesthetic properties of pantyhose, an image analysis and wear experiment were carried out. We analyzed both the area ratio of light, medium, and dark lightness areas and the position of three areas in the distribution of lightness difference between legs with and without pantyhose fabric. The data was used to determine what effect these two variables have on the visual appeal of legs in pantyhose. Moreover, we examined the relationship between pantyhose size and women’s leg size on the attractiveness of legs in pantyhose made from single covered yarn with colored polyurethane core yarn. The results showed that, for the enhanced visual appeal of legs in pantyhose, (1) the area ratio and position of three areas in the distribution of lightness difference were very important factors; (2) it was desirable to design and produce the appropriate size of pantyhose for various sized legs in order to enhance their attractiveness.
著者
Ryozo Nagai Koichiro Kinugawa Hiroshi Inoue Hirotsugu Atarashi Yoshihiko Seino Takeshi Yamashita Wataru Shimizu Takeshi Aiba Masafumi Kitakaze Atsuhiro Sakamoto Takanori Ikeda Yasushi Imai Takashi Daimon Katsuhiro Fujino Tetsuji Nagano Tatsuaki Okamura Masatsugu Hori the J-Land Investigators
出版者
日本循環器学会
雑誌
Circulation Journal (ISSN:13469843)
巻号頁・発行日
pp.CJ-12-1618, (Released:2013-03-15)
参考文献数
24
被引用文献数
21 93

Background: A rapid heart rate (HR) during atrial fibrillation (AF) and atrial flutter (AFL) in left ventricular (LV) dysfunction often impairs cardiac performance. The J-Land study was conducted to compare the efficacy and safety of landiolol, an ultra-short-acting β-blocker, with those of digoxin for swift control of tachycardia in AF/AFL in patients with LV dysfunction. Methods and Results: The 200 patients with AF/AFL, HR ≥120beats/min, and LV ejection fraction 25–50% were randomized to receive either landiolol (n=93) or digoxin (n=107). Successful HR control was defined as ≥20% reduction in HR together with HR <110beats/min at 2h after starting intravenous administration of landiolol or digoxin. The dose of landiolol was adjusted in the range of 1–10μg·kg–1·min–1 according to the patient’s condition. The mean HR at baseline was 138.2±15.7 and 138.0±15.0beats/min in the landiolol and digoxin groups, respectively. Successful HR control was achieved in 48.0% of patients treated with landiolol and in 13.9% of patients treated with digoxin (P<0.0001). Serious adverse events were reported in 2 and 3 patients in each group, respectively. Conclusions: Landiolol was more effective for controlling rapid HR than digoxin in AF/AFL patients with LV dysfunction, and could be considered as a therapeutic option in this clinical setting.
著者
Masa-aki Kishida Satoshi Muratsugu Ryota Sakamoto Tetsuro Kusamoto Hiroshi Nishihara
出版者
(社)日本化学会
雑誌
Chemistry Letters (ISSN:03667022)
巻号頁・発行日
pp.121264, (Released:2013-03-19)
被引用文献数
7

We prepared dimethyldihydropyrene (DHP) derivative 2 which possesses two ferrocenyl groups at the 4 and 9 positions through ethynylene linkers. 2 showed intense electronic communication between the two ferrocenyl groups, which is promoted by the highly developed π-orbital of the diethynylDHP moiety.