著者

内山田 康 O'DAY ROBIN O'DAY Robin

出版者

筑波大学

雑誌

特別研究員奨励費

巻号頁・発行日

2014-04-25

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From April 2016 to August 2016, Dr. O'Day did 4 months of ethnographic fieldwork and continued working with NG0s, Fukushima evacuees and activists working on the related issues. He worked with a group mothers who have evacuated from Fukushima to Tokyo with their children, a group of mothers who remained in Fukushima after the nuclear accident, a group of volunteers that identify themselves as “supporters” of those evacuees, a peace movement of women called “Mothers Against War”, and another student peace and pro-democracy movement called Student Emergency Action for Liberal Democracy (SEALDs). In addition, Dr. O'Day also engaged in participant observation research at political demonstrations, community events, and by volunteering in some disaster reconstruction projects.

著者

APATA Z. O.

出版者

The Center for African Area Studies, Kyoto University

雑誌

African Study Monographs (ISSN:02851601)

巻号頁・発行日

vol.11, no.3, pp.143-152, 1990-12

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This paper discusses the roles played by Lord Frederick Lugard in the creation of provincial administration in Northern Nigeria. During his tenure as the High Commissioner from 1900 to 1906, the provinces he created were more or less "paper" provinces. This was so as the British colonial government had just been established in Northern Nigeria and thus exercised little or no control over most of the provinces. As the creation of the provinces was not preceded by a thorough study, and understanding of the customs and the indigenous administrative system of the people, Lugard's policies created serious problems. For instance, some ethnic groups were placed in provinces where they should not be. This provoked reactions from the people. Some colonial officials also reacted unfavourably to the creation of the provincial administration because of the huge expenditure involved. During his period as Governor-General of Nigeria, 1912-1918, Lugard embarked on the amalgamation of some provinces in Northern Nigeria. Like his previous efforts, this failed to materialize. The failure could be blamed on the character of Lugard and the style of his administration, as well as the peculiar circumstances of the governed. In spite of these problems, the provincial structure created by Frederick Lugard formed the bedrock of the British administration in Northern Nigeria in particular, and Nigeria in general.

著者

D. CESANA O.J. BENEDICTOW R. BIANUCCI

出版者

The Anthropological Society of Nippon

雑誌

Anthropological Science (ISSN:09187960)

巻号頁・発行日

vol.125, no.1, pp.15-24, 2017 (Released:2017-04-27)

参考文献数

68

被引用文献数

11

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Spread by infected galleys coming from Kaffa (Crimea), the Black Death reached Genoa, as it now seems, in the late summer of 1347 AD. Genoa functioned as an epicentre from which the contagion was spread into the mainland through a complex system of routes, which linked Liguria to northern and central Italy. Along these routes various institutions were found, namely ‘ospitali’ (hospitals) and ‘stationes’ (stations), where traders and pilgrims stopped to rest and recuperate. In 2006 a multiple burial archaeologically dated to the second half/end of the 14th century was discovered in the cemetery pertaining to the ‘ospitale’ of San Nicolao (Genoa). The excavation showed that it contained the remains of four individuals: a 38–40 week pregnant woman with her fetus and two sub-adults. Stratigraphy showed that these individuals were buried simultaneously. Given that the dating of the burial fits the arrival of the Second Pandemic in Europe, it was hypothesized that they might have died during the Black Death epidemic. The identification of Yersinia pestis F1 antigen in three of four individuals corroborated this hypothesis. Here we report the first evidence of Y. pestis infection in 14th-century Liguria and discuss the possible mechanisms of plague dissemination from Genoa into the surrounding regions. In fact, the ‘ospitale’ of San Nicolao, located at 792 m a.s.l. into the Bracco Massif, was used as a resting place/hostel by traders and travellers (e.g. pilgrims heading for Rome). This ‘ospitale’ represented a key point leading into a system of pathways forming the initial part of the Vie Romee better known under the name of Via Francigena in the Italian territory and, as a consequence, was the ideal site from which plague could be disseminated.

著者

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Vinogradov V. B. Vivarelli I. Vlachos S. Vlasak M. Vogel M. Vokac P. Volpi G. Volpi M. von der Schmitt H. von Toerne E. Vorobel V. Vorobev K. Vos M. Voss R. Vossebeld J. H. Vranjes N. Vranjes Milosavljevic M. Vrba V. Vreeswijk M. Vuillermet R. Vukotic I. Vykydal Z. Wagner P. Wagner W. Wahlberg H. Wahrmund S. Wakabayashi J. Walder J. Walker R. Walkowiak W. Wallangen V. Wang C. Wang C. Wang F. Wang H. Wang H. Wang J. Wang J. Wang K. Wang R. Wang S. M. Wang T. Wang T. Wang X. Wanotayaroj C. Warburton A. Ward C. P. Wardrope D. R. Washbrook A. Watkins P. M. Watson A. T. Watson I. J. Watson M. F. Watts G. Watts S. Waugh B. M. Webb S. Weber M. S. Weber S. W. Webster J. S. Weidberg A. R. Weinert B. Weingarten J. Weiser C. Weits H. Wells P. S. Wenaus T. Wengler T. Wenig S. Wermes N. Werner M. Werner P. Wessels M. Wetter J. Whalen K. Wharton A. M. White A. White M. J. White R. White S. Whiteson D. Wickens F. J. Wiedenmann W. Wielers M. Wienemann P. Wiglesworth C. Wiik-Fuchs L. A M Wildauer A. Wilkens H. G. Williams H. H. Williams S. Willis C. Willocq S. Wilson J. A. Wingerter-Seez I. Winklmeier F. Winston O. J. Winter B. T. Wittgen M. Wittkowski J. Wollstadt S. J. Wolter M. W. Wolters H. Wosiek B. K. Wotschack J. Woudstra M. J. Wozniak K. W. Wu M. Wu M. Wu S. L. Wu X. Wu Y. Wyatt T. R. Wynne B. M. Xella S. Xu D. Xu L. Yabsley B. Yacoob S. Yakabe R. Yamaguchi D. Yamaguchi Y. Yamamoto A. Yamamoto S. Yamanaka T. Yamauchi K. Yamazaki Y. Yan Z. Yang H. Yang H. Yang Y. Yang Z. Yao W. M. Yap Y. C. Yasu Y. Yatsenko E. Yau Wong K. H. Ye J. Ye S. Yeletskikh I. Yen A. L. Yildirim E. Yorita K. Yoshida R. Yoshihara K. Young C. Young C. J S Youssef S. Yu D. R. Yu J. Yu J. M. Yu J. Yuan L. Yuen S. P Y Yusuff I. Zabinski B. Zaidan R. Zaitsev A. M. Zakharchuk N. Zalieckas J. Zaman A. Zambito S. Zanello L. Zanzi D. Zeitnitz C. Zeman M. Zemla A. Zeng J. C. Zeng Q. Zengel K. Zenin O. Ženiš T. Zerwas D. Zhang D. Zhang F. Zhang G. Zhang H. Zhang J. Zhang L. Zhang R. Zhang R. Zhang X. Zhang Z. Zhao X. Zhao Y. Zhao Z. Zhemchugov A. Zhong J. Zhou B. Zhou C. Zhou L. Zhou L. Zhou M. Zhou N. Zhu C. G. Zhu H. Zhu J. Zhu Y. Zhuang X. Zhukov K. Zibell A. Zieminska D. Zimine N. I. Zimmermann C. Zimmermann S. Zinonos Z. Zinser M. Ziolkowski M. Živkovic L. Zobernig G. Zoccoli A. zur Nedden M. Zurzolo G. Zwalinski L.

出版者

Elsevier

雑誌

Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics (ISSN:03702693)

巻号頁・発行日

vol.756, pp.52-71, 2016-05-10

被引用文献数

12

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In the pp→tt process the angular distributions of top and anti-top quarks are expected to present a subtle difference, which could be enhanced by processes not included in the Standard Model. This Letter presents a measurement of the charge asymmetry in events where the top-quark pair is produced with a large invariant mass. The analysis is performed on 20.3 fb-1 of pp collision data at √s=8TeV collected by the ATLAS experiment at the LHC, using reconstruction techniques specifically designed for the decay topology of highly boosted top quarks. The charge asymmetry in a fiducial region with large invariant mass of the top-quark pair (mtt>0.75 TeV) and an absolute rapidity difference of the top and anti-top quark candidates within -2<|yt|-|yt|<2 is measured to be 4.2±3.2%, in agreement with the Standard Model prediction at next-to-leading order. A differential measurement in three tt- mass bins is also presented.

著者

Tatsuya Noda Yasuyuki Okumura Keiko Kan-o Toshibumi Taniguchi Sadao Suzuki Tomoaki Imamura

出版者

Society for Clinical Epidemiology

雑誌

Annals of Clinical Epidemiology (ISSN:24344338)

巻号頁・発行日

vol.4, no.4, pp.129-132, 2022 (Released:2022-10-03)

参考文献数

12

被引用文献数

2

著者

Yusuke Kondo Shoma Okada Susumu Ohtsuka Takeshi Hirabayashi Aya Adachi Makoto Urata Sho Toshino Hiroshi Miyake Nanako O. Ogawa Naohiko Ohkouchi

出版者

The Plankton Society of Japan, The Japanese Association of Benthology

雑誌

Plankton and Benthos Research (ISSN:18808247)

巻号頁・発行日

vol.13, no.2, pp.66-74, 2018-05-30 (Released:2018-05-24)

参考文献数

50

被引用文献数

1 1

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In this study, we investigated the trophic interactions between the Japanese giant box jellyfish, Morbakka virulenta, and fish in the central part of the Seto Inland Sea, western Japan, in autumn and winter. Occurring in the surface waters at nighttime, these cubomedusae, regardless of their size (1.5 to 22.5 cm in bell height), were found to be piscivorous, feeding mainly on the Japanese anchovy, as shown by their stomach contents analysis. This finding was supported by a stable isotopic analysis and by an unchanged cnidome, irrespective of the bell height of medusae. Their nocturnal occurrence near the surface often took place around the slack tide, during which the medusae were foraging with tentacles fully extended. Other associations between the medusae and fish were also observed at this time: presumed commensalism with juvenile Japanese horse mackerel, and predation by black scraper.

著者

Moises Torres-Gonzalez Jeff S. Volek Jose O. Leite Heather Fraser Maria Luz Fernandez

出版者

一般社団法人 日本動脈硬化学会

雑誌

Journal of Atherosclerosis and Thrombosis (ISSN:13403478)

巻号頁・発行日

vol.15, no.5, pp.235-243, 2008 (Released:2008-11-01)

参考文献数

42

被引用文献数

4 9

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Aim: There is limited information on how dietary carbohydrate restriction (CR) or the combination of dietary cholesterol (chol) and CR may affect atherosclerosis development. Guinea pigs were used to evaluate the effects of chol and CR on aortic cholesterol accumulation, mechanical properties of aortas and cytokine production.Methods: Ten male guinea pigs were fed either low (L) or high (H) chol in combination with CR or high carbohydrate (control) for 12 wk.Results: Groups fed the high chol (control-H and CR-H) had significantly higher concentrations of cholesterol in aortas and higher activity of serum phospholipase A2 than the L groups. CR resulted in significantly lower concentrations of small LDL particles and aortic cytokines and chemokynes than the control groups. Aortas from the control-H and the CR-L were stiffer than those from the control-L and the CR-H groups. This finding could be explained by the reduction in arterial stiffness during the early stages of atherosclerotic.Conclusion: these results demonstrate that CR has a major impact on atherogenicity.

著者

Kenji Fujino Yoshihiro Kawahara Kanako O. Koyanagi Kenta Shirasawa

出版者

Japanese Society of Breeding

雑誌

Breeding Science (ISSN:13447610)

巻号頁・発行日

pp.20089, (Released:2021-02-17)

被引用文献数

8

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Understanding genetic diversity among local populations is a primary goal of modern crop breeding programs. Here, we demonstrated the genetic relationships of rice varieties in Hokkaido, Japan, one of the northern limits of rice cultivation around the world. Furthermore, artificial selection during rice breeding programs has been characterized using genome sequences. We utilized 8,565 single nucleotide polymorphisms and insertion/deletion markers distributed across the genome in genotype-by-sequencing for genetic diversity analyses. Phylogenetics, genetic population structure, and principal component analysis showed that a total of 110 varieties were classified into four distinct clusters according to different populations geographically and historically. Furthermore, the genome sequences of 19 rice varieties along with historic representations in Hokkaido, nucleotide diversity and FST values in each cluster revealed that artificial selection of elite phenotypes focused on chromosomal regions. These results clearly demonstrated the history of the selections on agronomic traits as genome sequences among current rice varieties from Hokkaido.

著者

Naoyoshi Matsuda Masaki O. Abe

出版者

Japanese Cognitive Science Society

雑誌

認知科学 (ISSN:13417924)

巻号頁・発行日

vol.29, no.4, pp.587-594, 2022-12-01 (Released:2022-12-15)

参考文献数

28

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Imitation-inhibition training, requiring the inhibition of automatic imitative tendencies, has been proposed to enhance self-other distinction. Previous studies have demonstrated the effect of imitation-inhibition training in the improvement of one’s ability to not only understand others’ visual perspectives but also to empathize with them. We investigated the relationship between training and empathy in the recognition of others’ emotional states. All participants were trained on the first day and completed the self-reported empathy and facial expression recognition task the next day. The task consisted of a facial mimicry restricted block and an unrestricted block. In the restricted block, participants had to hold chopsticks horizontally with their mouths, which interfered with facial mimicry. The facial muscle activity and facial stimuli of participants were different in the restricted block. We found that imitation-inhibition training increased self-reported empathy. With respect to facial expression recognition, the performance of the control group declined due to interference with facial mimicry, while that of the imitation-inhibition training group did not. These results suggest that imitation-inhibition training increases self-reported empathy and allows for a similar level of recognition of others’ emotional states, regardless of discrepancies between the condition of self and others.

著者

Ji-Yun Kim Da-Haeng Kang Joon-Hee Lee Se-Min O Jae-Keun Jeon

出版者

The Society of Physical Therapy Science

雑誌

Journal of Physical Therapy Science (ISSN:09155287)

巻号頁・発行日

vol.29, no.1, pp.119-122, 2017 (Released:2017-01-31)

参考文献数

25

被引用文献数

6

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[Purpose] To investigate the effects of pre-induced muscle damage vibration stimulation on the pressure-pain threshold and muscle-fatigue-related metabolites of exercise-induced muscle damage. [Subjects and Methods] Thirty healthy, adult male subjects were randomly assigned to the pre-induced muscle damage vibration stimulation group, post-induced muscle damage vibration stimulation group, or control group (n=10 per group). To investigate the effects of pre-induced muscle damage vibration stimulation, changes in the pressure-pain threshold (lb), creatine kinase level (U/L), and lactate dehydrogenase level (U/L) were measured and analyzed at baseline and at 24 hours, 48 hours, and 72 hours after exercise. [Results] The pressure-pain thresholds and concentrations of creatine kinase and lactate dehydrogenase varied significantly in each group and during each measurement period. There were interactions between the measurement periods and groups, and results of the post-hoc test showed that the pre-induced muscle damage vibration stimulation group had the highest efficacy among the groups. [Conclusion] Pre-induced muscle damage vibration stimulation is more effective than post-induced muscle damage vibration stimulation for preventing muscle damage.

著者

Yuichi Ozaki Hector M. Garcia-Garcia Solomon S. Beyene Alexandre Hideo-Kajita Kayode O. Kuku Paul Kolm Ron Waksman

出版者

The Japanese Circulation Society

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

vol.83, no.7, pp.1480-1488, 2019-06-25 (Released:2019-06-25)

参考文献数

25

被引用文献数

16 22

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Background:Statin therapy has been shown to result in coronary plaque regression, but the relationship between statin use and stabilization of coronary plaque has not been elucidated. We conducted a systematic review and meta-analysis to evaluate the effect of statin therapy on fibrous cap thickness (FCT) on optical coherence tomography (OCT).Methods and Results:Nine OCT studies (6 randomized controlled trials and 3 observational studies) were enrolled with a total of 341 patients (390 lesions). Arms of the studies were grouped according to statin type and/or dose. Random effects meta-analysis was used to estimate a pooled mean change in FCT from baseline to follow-up. The overall effect mean FCT change was 67.7 µm (95% CI: 51.4–84.1, I2=95.0%, P<0.001). All statin groups had an increase in FCT, but the magnitude of the increase differed according to the statin. Two homogeneous subgroups with I2=0 were identified: mean FCT change was 27.8 µm (for subgroup atorvastatin 5 mg and rosuvastatin), and 61.9 µm (for subgroup atorvastatin 20 mg, fluvastatin 30 mg, and pitavastatin 4 mg). On meta-regression modeling, statin therapy alone explained most of the change in FCT.Conclusions:Statin therapy induced a significant increase in FCT as assessed on OCT, independent of coronary risk factors and other medications.

著者

edited by Keith M. Henderson and O.P. Dwivedi foreword by Ferrel Heady

出版者

St. Martin's Press

巻号頁・発行日

1999

著者

I/O編集部編集

出版者

工学社

巻号頁・発行日

1989

著者

Yoon C. Kang S.H. Yang J.O. Noh D.J. Indiragandhi P. Kim G.H.

出版者

日本農薬学会

巻号頁・発行日

vol.34, no.2, pp.77-88, 2009 (Released:2011-03-05)

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T型チューブの嗅覚計を用いて、精油17種類のチャバネゴキブリに対する忌避効果を調べた。柑橘類であるグレープフルーツ、レモン、ライムおよびオレンジより得たものを含む5種類の精油は、70.0から96.7%の範囲で良好な効果を示した。各精油はワモンゴキブリおよびクロゴキブリに対しても同等の活性を示した。ガスクロマトグラフィー(GC)およびGC-質量分析の解析から、柑橘油類のこの効果における主成分はリモネン、β-ピネンおよびγ-テルピネンであり、特にリモネンが主な成分であることがわかった。これらの化合物の忌避効果は用量とゴキブリの種によって異なった。オレンジ油を除く柑橘類の精油では、微量成分も忌避活性に寄与しているようであった。オレンジ油の場合には、活性の発現にはほとんどリモネンのみがかかわっていた。柑橘油および各テルペン類の活性において、3種類のゴキブリに対する忌避効果にはほとんど差がなかった。

著者

Tadahisa Sugiura Chitaru Kurihara Masashi Kawabori Andre C. Critsinelis Andrew B. Civitello Jeffrey A. Morgan O. H. Frazier

出版者

The Editorial Committee of Annals of Thoracic and Cardiovascular Surgery

雑誌

Annals of Thoracic and Cardiovascular Surgery (ISSN:13411098)

巻号頁・発行日

vol.27, no.1, pp.64-67, 2021 (Released:2021-02-20)

参考文献数

5

被引用文献数

1 3

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An increasing number of children with congenital heart disease are surviving into adulthood and subsequently developing end-stage heart failure. Two example populations are adults who have been previously operated on for congenitally corrected transposition of the great arteries (CCTGA) and transposition of the great arteries (TGA). Implantation of a continuous flow left ventricular assist device (CF-LVAD) in these patients can present unusual anatomical and physiologic challenges. In this report, we describe outcomes of CF-LVAD implantation in three such patients. These cases demonstrate the feasibility of implanting a CF-LVAD in patients who have undergone surgery for CCTGA and/or TGA.

著者

O.ノイゲバウアー著 矢野道雄 斎藤潔訳

出版者

恒星社厚生閣

巻号頁・発行日

1990

著者

Imanishi Tadashi Itoh Takeshi Suzuki Yutaka O'Donovan Claire Fukuchi Satoshi Koyanagi Kanako O. Barrero Roberto A. Tamura Takuro Yamaguchi-Kabata Yumi Tanino Motohiko Yura Kei Miyazaki Satoru Ikeo Kazuho Homma Keiichi Kasprzyk Arek Nishikawa Tetsuo Hirakawa Mika Thierry-Mieg Jean Thierry-Mieg Danielle Ashurst Jennifer Jia Libin Nakao Mitsuteru Thomas Michael A. Mulder Nicola Karavidopoulou Youla Jin Lihua Kim Sangsoo Yasuda Tomohiro Lenhard Boris Eveno Eric Suzuki Yoshiyuki Yamasaki Chisato Takeda Jun-ichi Gough Craig Hilton Phillip Fujii Yasuyuki Sakai Hiroaki Tanaka Susumu Amid Clara Bellgard Matthew Bonaldo Maria de Fatima Bono Hidemasa Bromberg Susan K. Brookes Anthony J. Bruford Elspeth Carninci Piero Chelala Claude Couillault Christine Souza Sandro J. de Debily Marie-Anne Devignes Marie-Dominique Dubchak Inna Endo Toshinori Estreicher Anne Eyras Eduardo Fukami-Kobayashi Kaoru R. Gopinath Gopal Graudens Esther Hahn Yoonsoo Han Michael Han Ze-Guang Hanada Kousuke Hanaoka Hideki Harada Erimi Hashimoto Katsuyuki Hinz Ursula Hirai Momoki Hishiki Teruyoshi Hopkinson Ian Imbeaud Sandrine Inoko Hidetoshi Kanapin Alexander Kaneko Yayoi Kasukawa Takeya Kelso Janet Kersey Paul Kikuno Reiko Kimura Kouichi Korn Bernhard Kuryshev Vladimir Makalowska Izabela Makino Takashi Mano Shuhei Mariage-Samson Regine Mashima Jun Matsuda Hideo Mewes Hans-Werner Minoshima Shinsei Nagai Keiichi Nagasaki Hideki Nagata Naoki Nigam Rajni Ogasawara Osamu Ohara Osamu Ohtsubo Masafumi Okada Norihiro Okido Toshihisa Oota Satoshi Ota Motonori Ota Toshio Otsuki Tetsuji Piatier-Tonneau Dominique Poustka Annemarie Ren Shuang-Xi Saitou Naruya Sakai Katsunaga Sakamoto Shigetaka Sakate Ryuichi Schupp Ingo Servant Florence Sherry Stephen Shiba Rie Shimizu Nobuyoshi Shimoyama Mary Simpson Andrew J. Soares Bento Steward Charles Suwa Makiko Suzuki Mami Takahashi Aiko Tamiya Gen Tanaka Hiroshi Taylor Todd Terwilliger Joseph D. Unneberg Per Veeramachaneni Vamsi Watanabe Shinya Wilming Laurens Yasuda Norikazu Yoo Hyang-Sook Stodolsky Marvin Makalowski Wojciech Go Mitiko Nakai Kenta Takagi Toshihisa Kanehisa Minoru Sakaki Yoshiyuki Quackenbush John Okazaki Yasushi Hayashizaki Yoshihide Hide Winston Chakraborty Ranajit Nishikawa Ken Sugawara Hideaki Tateno Yoshio Chen Zhu Oishi Michio Tonellato Peter Apweiler Rolf Okubo Kousaku Wagner Lukas Wiemann Stefan Strausberg Robert L. Isogai Takao Auffray Charles Nomura Nobuo Gojobori Takashi Sugano Sumio

出版者

Public Library of Science

雑誌

PLoS Biology (ISSN:15449173)

巻号頁・発行日

vol.2, no.6, pp.856-875, 2004-06

被引用文献数

3 226

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The human genome sequence defines our inherent biological potential; the realization of the biology encoded therein requires knowledge of the function of each gene. Currently, our knowledge in this area is still limited. Several lines of investigation have been used to elucidate the structure and function of the genes in the human genome. Even so, geneprediction remains a difficult task, as the varieties of transcripts of a gene may vary to a great extent. We thus performed an exhaustive integrative characterization of 41,118 full-length cDNAs that capture the gene transcripts as complete functional cassettes, providing an unequivocal report of structural and functional diversity at the gene level.Our international collaboration has validated 21,037 human gene candidates by analysis of high-quality full-length cDNA clones through curation using unified criteria. This led to the identification of 5,155 new gene candidates. It also manifested the most reliable way to control the quality of the cDNA clones. We have developed a human gene database, called the H-Invitational Database (H-InvDB; http://www.h-invitational.jp/). It provides the following:integrative annotation of human genes, description of gene structures, details of novel alternative splicing isoforms, non-protein-coding RNAs, functional domains, subcellular localizations, metabolic pathways, predictions of protein three-dimensional structure, mapping of known single nucleotide polymorphisms (SNPs), identification of polymorphic microsatellite repeats within human genes, and comparative results with mouse full-length cDNAs. The H-InvDB analysis has shown that up to 4% of the human genome sequence (National Center for Biotechnology Information build 34 assembly) may contain misassembled or missing regions. We found that 6.5% of the human gene candidates(1,377 loci) did not have a good protein-coding open reading frame, of which 296 loci are strong candidates for nonprotein-coding RNA genes. In addition, among 72,027 uniquely mapped SNPs and insertions/deletions localized within human genes, 13,215 nonsynonymous SNPs, 315 nonsense SNPs, and 452 indels occurred in coding regions. Together with 25 polymorphic microsatellite repeats present in coding regions, they may alter protein structure, causingphenotypic effects or resulting in disease. The H-InvDB platform represents a substantial contribution to resources needed for the exploration of human biology and pathology.

著者

Jennifer Edmond Natasa Bulatovic Alexander O'Connor

出版者

日本デジタル・ヒューマニティーズ学会

雑誌

Journal of the Japanese Association for Digital Humanities (ISSN:21887276)

巻号頁・発行日

vol.1, no.1, pp.107-122, 2015-09-02 (Released:2015-09-02)

参考文献数

17

被引用文献数

2

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The Collaborative EuropeaN Digital Archival Research Infrastructure (CENDARI) project has developed a new virtual environment for humanities research, reimagining the analogue landscape of research sources for medieval and modern history and humanities research infrastructure models for the digital age. To achieve this, the project has needed to be sensitive to the ways in which historical research practices in the 21st Century are distinct from those of earlier eras, harnessing the affordances of technology to reveal connections and support or refute hypotheses, enabling transnational approaches, and federating sources beyond the well-known and across the largely national organization paradigms that dominate within traditional knowledge infrastructures (libraries, archives and museums). This paper describes both the user-centered development methodology deployed by the project and the resulting technical architecture adopted to meet these challenging requirements. The resulting system is a robust ‘enquiry environment’ able to integrate a variety of data types and standards with bespoke tools for the curation, annotation, communication and validation of historical insight.

著者

Tatsuya Noda Yasuyuki Okumura Keiko Kan-o Toshibumi Taniguchi Sadao Suzuki Tomoaki Imamura

出版者

Society for Clinical Epidemiology

雑誌

Annals of Clinical Epidemiology (ISSN:24344338)

巻号頁・発行日

pp.22016, (Released:2022-08-03)

被引用文献数

2

著者

レイモンド O.フォークナー原著 當麻夏雄訳著

出版者

中央公論事業出版(製作)

巻号頁・発行日

2003