著者

Myung-Mo Lee Doo-Chul Shin Chang-Ho Song

出版者

理学療法科学学会

雑誌

Journal of Physical Therapy Science (ISSN:09155287)

巻号頁・発行日

vol.28, no.7, pp.2019-2024, 2016 (Released:2016-07-29)

参考文献数

31

被引用文献数

36

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[Purpose] This study was aimed at investigating the preliminary therapeutic efficacy and usefulness of canoe game-based virtual reality training for stroke patients. [Subjects and Methods] Ten stroke patients were randomly assigned to an experimental group (EG; n=5) or a control group (CG; n=5). Patients in both groups participated in a conventional rehabilitation program, but those in the EG additionally participated in a 30-min canoe game-based virtual reality training program 3 days a week for 4 weeks. Therapeutic efficacy was assessed based on trunk postural stability, balance, and upper limb motor function. In addition, the usefulness of canoe game-based virtual reality training was assessed in the EG and therapist group (TG; n=20), which consisted of physical and occupational therapists, by using the System Usability Scale (SUS). [Results] Improvements in trunk postural stability, balance, and upper limb motor function were observed in the EG and CG, but were greater in the EG. The mean SUS scores in the EG and TG were 71 ± 5.2 and 74.2 ± 4.8, respectively. [Conclusion] Canoe game-based virtual reality training is an acceptable and effective intervention for improving trunk postural stability, balance, and upper limb motor function in stroke patients.

著者

Jung-Sub Shin Hee-Won Park Gyo In Hyun Kyu Seo Tae Hyung Won Kyoung Hwa Jang Byung-Goo Cho Chang Kyun Han Jongheon Shin

出版者

公益社団法人日本薬学会

雑誌

Chemical and Pharmaceutical Bulletin (ISSN:00092363)

巻号頁・発行日

pp.c16-00240, (Released:2016-07-05)

参考文献数

17

被引用文献数

14

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Panax ginseng C.A. Meyer is one of the most popular medicinal herbs in Asia and the chemical constituents are changed by processing methods such as steaming or sun drying. Metabolomic analysis was performed to distinguish age discrimination of four- and six-year-old red ginseng using ultra-performance liquid chromatography quadruple time of flight mass spectrometry (UPLC-QToF-MS) with multivariate statistical analysis. Principal component analysis (PCA) showed clear discrimination between extracts of red ginseng of different ages and suggest totally six discrimination markers (two for four-year-old and four for six-year-old red ginseng). Among these, one marker was isolated and the structure determined by NMR spectroscopic analysis was 13-cis-docosenamide (marker 6-1) from six-year-old red ginseng. This is the first report of a metabolomic study regarding the age differentiation of red ginseng using UPLC-QToF-MS and determination of the structure of the marker. These results will contribute to the quality control and standardization as well as provide a scientific basis for pharmacological research on red ginseng.

著者

Nishizawa Seiya Odaka Masatsugu Takahashi Yoshiyuki O. Sugiyama Ko-ichiro Nakajima Kensuke Ishiwatari Masaki Takehiro Shin-ichi Yashiro Hisashi Sato Yousuke Tomita Hirofumi Hayashi Yoshi-Yuki

出版者

American Geophysical Union

雑誌

Geophysical Research Letters (ISSN:00948276)

巻号頁・発行日

vol.43, no.9, pp.4180-4188, 2016-05-16

被引用文献数

19

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火星ダストデビルの性質を解明-火星天気予報や火星有人探査への一歩-. 京都大学プレスリリース. 2016-07-27.

著者

Miriam Valle Arizaga Oscar Fabián Villalobos Navarro Carlos Roman Castillo Martinez Esmeralda Judith Cruz Gutiérrez Humberto Antonio López Delgado Shin‑ichi Yamamoto Kazuo Watanabe Takao Niino

出版者

一般社団法人 園芸学会

雑誌

The Horticulture Journal (ISSN:21890102)

巻号頁・発行日

pp.OKD-002, (Released:2016-07-16)

被引用文献数

18

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We modified the D cryo-plate protocol by paper mounting to the cryo-plate with alginate gel and shoot tips, and cryopreserved shoot tips of 13 potato genotypes (potato genetic resources in Mexico) using the revised and optimized D cryo-plate protocol. There were no significant differences in regrowth of cryopreserved shoot tips by addition of the paper mounting step to the base D cryo-plate protocol, besides a reduction in dropping shoot tips in steps during the whole procedure. Some steps of revised D cryo-plate protocol were optimized or reconfirmed, and the effect of optimizations such as cold-hardening, loading solution treatment, and post-rewarming treatment on the regeneration of shoot tips was studied. This optimized protocol was successfully applied to ‘B-71-240-2’ and 12 additional potato genotypes, resulting in 70.0%–93.3% regrowth with an average of 82.8% and stable storage for 1 year. When introducing new cryopreservation techniques, modification and optimization of the method are required to adjust to each laboratory’s circumstances. This optimized D cryo-plate method will facilitate cryobanking of potato and other plant genetic resources in Mexico for long-term preservation in a genebank.

著者

ISHIMARU Shin-ichi

出版者

北海道大學 = THE FACULTY OF SCIENCE, HOKKAIDO UNIVERSITY

雑誌

北海道大學理學部紀要 (ISSN:03682188)

巻号頁・発行日

vol.24, no.3, pp.173-181, 1986-03

著者

Kenichi Sakakura Yousuke Taniguchi Mitsunari Matsumoto Hiroshi Wada Shin-ichi Momomura Hideo Fujita

出版者

一般社団法人 インターナショナル・ハート・ジャーナル刊行会

雑誌

International Heart Journal (ISSN:13492365)

巻号頁・発行日

pp.15-421, (Released:2016-05-09)

被引用文献数

20

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Rotational atherectomy to an angulated calcified lesion is always challenging. The risk of catastrophic complications such as a burr becoming stuck or vessel perforation is greater when the calcified lesion is angulated. We describe the case of an 83-year-old female suffering from unstable angina. Diagnostic coronary angiography revealed an angulated calcified lesion in the proximal segment of the right coronary artery. We performed rotational atherectomy to the lesion, but intentionally did not advance the rotational atherectomy burr beyond the top of the angulation. We controlled the rotational atherectomy burr and stopped it just before the top of the angulation to avoid complications. Following rotational atherectomy, balloon dilatation with a non-compliant balloon was performed, and drug-eluting stents were successfully deployed. In this manuscript, we provide a review of the literature on this topic, and discuss how rotational atherectomy to an angulated calcified lesion should be performed.

著者

Sugiyama Shin Bauder Andreas Zahno Conradin Funk Martin

出版者

International Glaciological Society

雑誌

Annals of Glaciology (ISSN:02603055)

巻号頁・発行日

vol.46, pp.268-274, 2007-10

被引用文献数

28

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To study the past and future evolution of Rhonegletscher, Switzerland, a flowline model was developed to include valley shape effects more accurately than conventional flowband models. In the model, the ice flux at a gridpoint was computed by a two-dimensional ice-flow model applied to the valley cross-section. The results suggested the underestimation of the accumulation area, which seems to be a general problem of flowline modelling arising from the model's one-dimensional nature. The corrected mass balance was coupled with the equilibrium-line altitude (ELA) change, which was reconstructed for the period 1878–2003 from temperature and precipitation records, to run the model for the past 125 years. The model satisfactorily reproduced both changes in the terminus position and the total ice volume derived from digital elevation models of the surface obtained by analyses of old maps and aerial photographs. This showed the model's potential to simulate glacier evolution when an accurate mass balance could be determined. The future evolution of Rhonegletscher was evaluated with three mass-balance conditions: the mean for the period 1994–2003, and the most negative (2003) and positive (1978) mass-balance values for the past 50 years. The model predicted volume changes of –18%, –58% and +38% after 50 years for the three conditions, respectively.

著者

Kazuyuki Amano Shin-ichi Nakano Koichi Yamazaki

出版者

一般社団法人 情報処理学会

雑誌

Journal of Information Processing (ISSN:18826652)

巻号頁・発行日

vol.23, no.3, pp.252-257, 2015 (Released:2015-05-15)

参考文献数

5

被引用文献数

1

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The anti-slide packing is a packing of a number of three dimensional pieces of same size into a larger box such that none of them can slide in any direction. In this paper, we consider the problem of how to find a sparsest anti-slide packing. We give an IP formulation of this problem, and obtain the solutions for some small cases by using an IP solver. In addition, we give the upper and lower bounds on the ratio of the volume occupied by the pieces when the size of a box approaches infinity. For the case of piece size 2 × 2 × 1, we show that a sparsest anti-slide packing occupies at least 28.8% and at most 66.7% of the total volume.

著者

In Koo HWANG Jin Young CHUNG Dae Young YOO Sun Shin YI Hwa Young YOUN Je Kyung SEONG Yeo Sung YOON

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.72, no.3, pp.279-284, 2010 (Released:2010-04-03)

参考文献数

29

被引用文献数

10 30

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We compared the effects of acupuncture and electroacupuncture on cell proliferation and neuroblast differentiation using specific markers, Ki67 and doublecortin (DCX), in the subgranular zone of the dentate gyrus (SZDG) in 13-week old Wistar rats. Acupuncture and electroacupuncture were applied simultaneously in the acu-points, ST36 (Zusanli) and GV20 (Baihui), once a day for 3 weeks. Acupuncture and electroacupuncture at these acu-points significantly increased the number of Ki67-positive cells and DCX-immunoreactive neuroblasts compared to the control or sham acupuncture group. Electroacupuncture treatment significantly increased the number of well-developed (tertiary) dendrites in the SZDG compared to acupuncture treatment. These results suggest that both acupuncture and electroacupuncture increase neurogenesis in the normal, but that electroacupuncture has greater effects on neuroblast plasticity than acupuncture in the dentate gyrus.

著者

Li Yuan Shin Woongchul Okada Kazuhiro

出版者

北海道大学文学研究科

雑誌

Journal of the Graduate School of Letters (ISSN:18808832)

巻号頁・発行日

vol.11, pp.83-96, 2016-03

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This essay will address differences in orientation in early Japanese lexicography with regard to the Japanese rendering of definitions in a Chinese language dictionary. Most,if not all, premodern Japanese dictionaries took the form of rendering the headword in Chinese characters and Chinese words,while also offering a Japanese reading. This does not, however, entail that early Japanese lexicography was entirely oriented to the Chinese language:in fact,a representative portion of Japanese oriented language dictionaries were produced. Japanese readings in Japanese language dictionaries explain the Japanese use of the headword. Alternatively, Chinese-Japanese dictionaries, including Chinese character dictionaries, explain the Chinese use in the Japanese language. By virtue of this fact,they are not distinctive in their form. This essay attempts to distinguish which orientation a dictionary inclines to by focusing on its rendering of definitions of earlier Chinese dictionaries. Here,we will examine the nature of Japanese renditions in a Japanese dictionary,Ruiju myogi sho 類聚名義抄, cited from the Chinese character dictionary Tenrei bansho meigi 篆隷万象名義. Our findings suggest that Japanese renditions illustrate Chinese use rather than Japanese use, which accounts for differences in the Japanese readings and compiling strategies of the dictionaries.

著者

Kitayama Shuichi Zhang Rong Liu Tian-Yi Ueda Norihiro Iriguchi Shoichi Yasui Yutaka Kawai Yohei Tatsumi Minako Hirai Norihito Mizoro Yasutaka Iwama Tatsuaki Watanabe Akira Nakanishi Mahito Kuzushima Kiyotaka Uemura Yasushi Kaneko Shin

出版者

Elsevier Inc.

雑誌

Stem cell reports (ISSN:22136711)

巻号頁・発行日

vol.6, no.2, pp.213-227, 2016-02-09

被引用文献数

66

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ヒトiPS細胞から、免疫機能を活性化させる細胞の作製に成功. 京都大学プレスリリース. 2016-03-24.

著者

Jung-Sun Kim Hancheol Lee Yongsung Suh Hui-Nam Pak Geu-Ru Hong Chi Young Shim Cheol-Woong Yu Hyun-Jong Lee Woong-Chol Kang Eun-Seok Shin Rak-Kyeong Choi Saibal Kar Jai-Wun Park Do-Sun Lim Yangsoo Jang

出版者

日本循環器学会

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

pp.CJ-15-1134, (Released:2016-03-17)

参考文献数

28

被引用文献数

2 24

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Background:The aim of this study was to evaluate clinical outcome after left atrial appendage (LAA) occlusion in real clinical practice and compare between Amplatzer cardiac plug (ACP) and Watchman.Methods and Results:From October 2010 to February 2015, 96 successful LAA occlusion procedures were performed using either ACP (n=50) or Watchman device (n=46) in non-valvular atrial fibrillation (AF) patients (59 male; age, 65.1±9.4 years; CHADS2, 2.5±1.2; CHA2DS2-VASC, 3.9±1.6; HAS-BLED, 2.7±1.3). The procedure success rate was 96.8%. There were serious complications in 4 patients (4.1%; 2 cardiac tamponade, 1 device embolization, and 1 major bleed). The anticoagulation cessation rate after 6 weeks was 92.7%. During mean 21.9-month follow-up, the incidence of death, stroke, systemic embolization and major bleeding was 5.2%, 4.2%, 0% and 1.0%, respectively. On transesophageal echocardiography of 93 patients within 6 months after the procedure, 24 residual leaks were observed (25.8%; 2 mild, 18 moderate, and 4 major). Clinical outcome was similar for the 2 devices, but peridevice leakage was more frequent with the Watchman than the ACP.Conclusions:LAA occlusion was feasible in non-valvular AF patients with high risk of stroke and hemorrhage. The ACP and Watchman devices were similar in terms of procedural and clinical outcomes.

著者

相馬 伸一 ソウマ シンイチ Shin'ichi Sohma

雑誌

広島修大論集. 人文編

巻号頁・発行日

vol.40, no.1, pp.363-409, 1999-09-30

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This paper consists of the translation of two articles from 'Philosophers on Education' edited by Amelie Rorty (London, Routledge, 1998). Based on such an understanding that philosophy is implicitly pedagogical, this book aims to provide a historical description of educational viewpoints among various philosophers. In the former article entitled the Ruling History of Education, Rorty gives a brief historical overview of the history of educational ideas in terms of the history of philosophy. With her aim in mind, various contributors try to depict the educational ideas of philosophers, including relatively unfamiliar figures in the history of education such as Descartes, Hobbes, Spinoza and Leibniz. The latter article entitled Descartes, or the Cultivation of the Intellect, which was written by Daniel Garber, tries to understand Descartes' philosophy as educational thought. This attempt might give some suggestion as to how the framework of the hisotorical study on educational thought can be widened.

著者

根岸 紳 Shin Negishi

出版者

関西学院大学経済学部研究会

雑誌

経済学論究 (ISSN:02868032)

巻号頁・発行日

vol.66, no.1, pp.163-186, 2012-06

著者

Taishi Hayashida Kazuyoshi Nada Shin Hiratsuka

出版者

一般社団法人 園芸学会

雑誌

The Horticulture Journal (ISSN:21890102)

巻号頁・発行日

pp.MI-067, (Released:2015-12-19)

被引用文献数

1

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Since both artificial pollination and fruit thinning are necessary for marketable fruit production of Japanese pears (Pyrus pyrifolia (burm. f.) Nakai) in Japan, about a 20% fruit set is ideal without pollination because only 5% of flowers are actually subjected to fruit production. In this study, copper (Cu2+) and ferrous (Fe2+) ions were shown to be effective for inducing a nearly-ideal fruit set of the Japanese pear ‘Kosui’. Fruit induced by ferrous sulfate (FeSO4) solution or a Bordeaux mixture, which is a combination of copper sulfate (CuSO4), lime, and water, were parthenocarpic, because 1) self-pollen tube growth was not promoted by Cu2+ and Fe2+, 2) almost no perfect seeds were observed at harvest, and 3) Cu2+ and Fe2+ acted as strong inhibitors of pollen tube growth in vitro. The effective stage for inducing parthenocarpy was sprouting time to 4 days after anthesis in the Bordeaux mixture, and sprouting time to 4 days before anthesis in the FeSO4 solution. Annual changes in the effectiveness were found in both chemicals, and the Bordeaux mixture showed no inhibitory effect on the fruit set of cross-pollinated flowers. The growth of Bordeaux mixture-induced fruit was improved by gibberellin (GA) paste or GA paste mixed with N-(N-(2-chloro-4-pyridy1)-N'-phenylurea (CPPU) treatment of the fruit stalk; the treated fruit was about 100 g heavier than the untreated fruit. The GA paste treatment is currently conducted to promote fruit growth and maturation in ‘Kosui’ fruit production in Japan, and the Bordeaux mixture can be substituted for chemical fungicide generally used before anthesis to control scab and black spot disease. Accordingly, the Bordeaux mixture is a promising chemical for great labor-saving in ‘Kosui’ cultivation.

著者

Takashi Yokota Yasuo Kunii Shin Teshima Yasuo Yamada Toshihiro Saito Shu Kikuchi Hidemi Yamauchi

出版者

東北ジャーナル刊行会

雑誌

The Tohoku Journal of Experimental Medicine (ISSN:00408727)

巻号頁・発行日

vol.186, no.2, pp.121-130, 1998 (Released:2005-10-14)

参考文献数

16

被引用文献数

30 63

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A retrospective analysis was carried out on 93 patients with signet ring cell carcinoma of the stomach operated on between 1985 and 1995, to review the clinicopathologic characteristics from the database of gastric cancer at Sendai National Hospital. The results were compared with those for 590 patients with other types of gastric carcinoma. Women were afflicted as commonly as men in the signet ring cell carcinoma group. These patients tended to be younger and to have larger tumors. The histological type was commonly scirrhous and infiltrative. The survival of patients with signet ring cell carcinoma was worse than that of patients with other types of gastric cancer but the difference was not statistically significant. Patients with early signet ring cell carcinoma had a good prognosis, similar to that of the other groups. However, prognosis of patients with advanced signet ring cell carcinoma was poor compared with patients with other types of this disease. In multivariate analysis, the statistical significant prognostic factors were vascular microinvasion and tumor location. These findings suggest that signet ring cell carcinoma of the stomach should be regarded as a distinct type of gastric cancer.

著者

Eiji Kanamori Shin-ichi Kawaguchi Seiki Kuramitsu Tsutomu Kouyama Midori Murakami

出版者

一般社団法人 日本生物物理学会

雑誌

Biophysics and Physicobiology (ISSN:21894779)

巻号頁・発行日

vol.12, pp.47-56, 2015 (Released:2015-10-10)

参考文献数

23

被引用文献数

1 6

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The crystal structures of citrate synthase from the thermophilic eubacteria Thermus thermophilus HB8 (TtCS) were determined for an open form at 1.5 Å resolution and for closed form at 2.3 Å resolution, respectively. In the absence of ligands TtCS in the open form was crystalized into a tetragonal form with a single subunit in the asymmetric unit. TtCS was also co-crystallized with citrate and coenzyme-A to form an orthorhombic crystal with two homodimers in the asymmetric unit. Citrate and CoA are found in the active site situated between the large domain and the small domain in all subunit whereas the complex shows two distinct closed conformations, the fully closed form and partially closed form.Structural comparisons are performed to describe conformational changes associated with binding of products of TtCS. Upon binding of citrate, basic residues in the active site move toward citrate and make a hydrogen bond network in the active site, inducing a large-scale rotation of the small domain relative to the large domain. CoA is sandwiched between the small and large domains and then the cysteamine tail is inserted into the active site with a cooperative rotation around mainchain dihedrals in the hinge region connecting helices M and N. According to this rotation these helices are extended to close the active site completely. The considerable flexibility and structural rearrangements in the hinge region are crucial for an ordered bibi reaction in catalysis for microbial CSs.

著者

Masayoshi Kumagai Shigeo Sato Shigeru Suzuki Muneyuki Imafuku Hitoshi Tashiro Shin-ichi Ohya

出版者

一般社団法人 日本鉄鋼協会

雑誌

ISIJ International (ISSN:09151559)

巻号頁・発行日

vol.55, no.7, pp.1489-1495, 2015-07-15 (Released:2015-07-30)

参考文献数

19

被引用文献数

1 3

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Measurement of the residual stresses in cold-drawn pearlitic steel wire was conducted using an energy dispersive X-ray diffraction technique. The residual stresses of the ferrite and cementite phases were determined for different crystal orientations and large residual stresses were found to exist in the cold-drawn pearlitic steel wire. The residual stresses in the ferrite phase were compressive in the axial direction but nearly zero in the hoop and radial directions. In addition, the residual stresses of the reflection indices for the ferrite phase were similar to one another. For the cementite phase, while tensile residual stress existed in the axial direction, compressive residual stress existed in the hoop and radial directions. These stresses in the ferrite phase in the axial direction and cementite phase in all directions decreased along the radial positions. A residual stress state model was proposed on the basis of the aligned lamellar structure along the drawing direction; the model explains the effect of the lamellar direction on residual stress. Reanalysis of the wire sample using the proposed model provided residual strains and stresses in the lamellar direction that were different from the average values estimated using the simple stress analysis method.

著者

Shin-ichi Ishikawa Ryo Motoya Satoko Sasagawa Takahito Takahashi Isa Okajima Yasuchika Takeishi Cecilia A. Essau

出版者

東北ジャーナル刊行会

雑誌

The Tohoku Journal of Experimental Medicine (ISSN:00408727)

巻号頁・発行日

vol.236, no.2, pp.115-122, 2015 (Released:2015-05-30)

参考文献数

37

被引用文献数

2 10

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On March 11, 2011, the Great East Japan Earthquake devastated the Tohoku region, which led to a tsunami and a nuclear disaster. While these three disasters caused tremendous physical damage, their psychological impact remains unclear. The present study evaluated traumatic responses, internalizing (i.e., anxiety and depression), and externalizing (i.e., anger) symptoms among Japanese young people in the immediate aftermath and 2.5 years later. A total of 435 undergraduates were recruited from universities in three differentially exposed regions: Fukushima, Tokyo, and Kyoto. They completed a set of questionnaires retrospectively (i.e., September to December 2013) to measure their traumatic responses, anxiety and depressive symptoms, functional impairment, and anger immediately after the disaster and 2.5 years later. Participants in Tokyo had the highest level of traumatic response and internalizing symptoms immediately after the earthquake, whereas those in Fukushima had significantly higher levels of trait anger, anger-in (holding one’s anger in), and anger-out (expressing one’s anger externally). In Kyoto, the levels of anxiety and depression after 2.5 years were significantly higher than they were immediately after the disasters. In conclusion, anger symptoms were high among young people who lived at or near the center of the disasters, while anxiety and depression were high among those who lived far away from the disasters. These findings suggest the importance of providing mental health services to young people who did not live near the disaster area as well as to those living in the directly affected area.

著者

Young-Shin Lee Sea-Hyun Bae Sung-Hee Lee Kyung-Yoon Kim

出版者

東北ジャーナル刊行会

雑誌

The Tohoku Journal of Experimental Medicine (ISSN:00408727)

巻号頁・発行日

vol.236, no.1, pp.81-88, 2015 (Released:2015-05-16)

参考文献数

42

被引用文献数

2 22

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Owing to the reduced capacity for information processing following a stroke, patients commonly present with difficulties in performing activities of daily living that combine two or more tasks. To address this problem, in the present study, we investigated the effects of neurofeedback training on the abilities of stroke patients to perform dual motor tasks. We randomly assigned 20 patients who had sustained a stroke within the preceding 6 months to either a pseudo-neurofeedback (n = 10) or neurofeedback (n = 10) group. Both groups participated in a general exercise intervention for 8 weeks, three times a week for 30 min per session, under the same conditions. An electrode was secured to the scalp over the region of the central lobe (Cz), in compliance with the International 10-20 System. The electrode was inactive for the pseudo-training group. Participants in the neurofeedback training group received the 30-min neurofeedback training per session for reinforcing the sensorimotor rhythm. Electroencephalographic activity of the two groups was compared. In addition, selected parameters of gait (velocity, cadence [step/min], stance phase [%], and foot pressure) were analyzed using a 10-m walk test, attention-demanding task, walk task and quantified by the SmartStep system. The neurofeedback group showed significantly improved the regulation of the sensorimotor rhythm (p < 0.001) and ability to execute dual tasks (p < 0.01). Significant improvements on selected gait parameters (velocity and cadence; p < 0.05) were also observed. We thus propose that the neurofeedback training is effective to improve the dual-task performance in stroke patients.