著者

Shotaro Usuzaki Yuki Arikawa Hisaaki Yamaba Kentaro Aburada Shin-Ichiro Kubota Mirang Park Naonobu Okazaki

出版者

Information Processing Society of Japan

雑誌

Journal of Information Processing (ISSN:18826652)

巻号頁・発行日

vol.26, pp.257-266, 2018 (Released:2018-03-15)

参考文献数

18

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Distributed Denial-of-Service (DDoS) attack detection systems are classified into a signature based approach and an anomaly based approach. However, such methods tend to suffer from low responsiveness. On the other hand, real-time burst detection which is used in data mining offers two advantages over traditional statistical methods. First, it can be used for real-time detection when an event is occurring, and second, it can work with less processing as information about events are compressed, even if a large number of events occur. Here, the authors add the function for attack detection in real-time burst detection technique, and propose a highly responsive DDoS attack detection technique. This paper performs experiments to evaluate its effectiveness, and discusses its detection accuracy and processing performance.

著者

FermilabE653Collaboration USHIDA N. MOKHTARANI A. PAOLONE V.S. VOLK J.T. WILCOX J.O. YAGER P.M. EDELSTEIN R.M. FREYBERGER A.P. GIBAUT D.B. LIPTON R.J. NICHOLS W.R. POTTER D.M. RUSS J.S. ZHANG C. ZHANG Y. JANG H.I. KIM J.Y. KIM T.I. LIM I.T. PAC M.Y. BALLER B.R. STEFANSKI R.J. NAKAZAWA K. CHUNG K.S. CHUNG S.H. KIM D.C. PARK I.G. PARK M.S. SONG J.S. YOON C.S. CHIKAWA M. ABE T. FUJII T. FUJIOKA G. FUJIWARA K. FUKUSHIMA H. HARA T. TAKAHASHI Y. TARUMA K. TSUZUKI Y. YOKOYAMA C. CHANG S.D. CHEON B.G. CHO J.H. KANG J.S. KIM C.O. KIM K.Y. KIM T.Y. LEE J.C. LEE S.B. LIM G.Y. NAM S.W. SHIN T.S. SIM K.S. WOO J.K. ISOKANE Y. TSUNEOKA Y. AOKI S. GAUTHIER A. HOSHINO K. KITAMURA H. KOBAYASHI M. MIYANISHI M. NAKAMURA K. NAKAMURA M. NAKAMURA Y. NAKANISHI S. NIU K. NIWA K. NOMURA M. TAJIMA H. YOSHDA S. ARYAL M. DUNLEA J.M. FREDERIKSEN S.G. KURAMATA S. LUNDBERG B.G. OLEYNIK G.A. REAY N.W. REIBEL K. SIDWELL R.A. STANTON N.R. MORIYAMA K. SHIBATA H. KALBFLEISCH G.R. SKUBIC P. SNOW J.M. WILLIS S.E. KUSUMOTO O. NAKAMURA K. OKUSAWA T. TERANAKA M. TOMINAGA T. YOSHIDA T. YUUKI H. OKABE H. YOKOTA J. ADACHI M. KAZUNO M. NIU E. SHIBUYA H. WATANABE S. OHTSUKA I. SATO Y. TEZUKA I. BAHK S.Y. KIM S.K. Aichi University of Education Aichi University of Education University of California (Davis) University of California (Davis) University of California (Davis) University of California (Davis) University of California (Davis) Carnegie-Mellon University Carnegie-Mellon University Carnegie-Mellon University Carnegie-Mellon University Carnegie-Mellon University Carnegie-Mellon University Carnegie-Mellon University Carnegie-Mellon University Carnegie-Mellon University Chonnam National University Chonnam National University Chonnam National University Chonnam National University Chonnam National University Fermi National Accelerator Laboratory Fermi National Accelerator Laboratory Gifu University Gyeongsang National University Gyeongsang National University Gyeongsang National University Gyeongsang National University Gyeongsang National University Gyeongsang National University Gyeongsang National University Kinki University Kobe University Kobe University Kobe University Kobe University Kobe University Kobe University Kobe University Kobe University Kobe University Kobe University Korea University Korea University Korea University Korea University Korea University Korea University Korea University Korea University Korea University Korea University Korea University Korea University Korea University Korea University Nagoya Institute of Technology Nagoya Institute of Technology Nagoya University Nagoya University Nagoya University Nagoya University Nagoya University Nagoya University Nagoya University Nagoya University Nagoya University Nagoya University Nagoya University Nagoya University Nagoya University Nagoya University Nagoya University The Ohio State University The Ohio State University The Ohio State University The Ohio State University The Ohio State University The Ohio State University The Ohio State University The Ohio State University The Ohio State University The Ohio State University Okayama University Okayama University University of Oklahoma University of Oklahoma University of Oklahoma University of Oklahoma Osaka City University Osaka City University Osaka City University Osaka City University Osaka City University Osaka City University Osaka City University Science Education Institute of Osaka Prefecture Science Education Institute of Osaka Prefecture Toho University Toho University Toho University Toho University Toho University Utsunomiya University Utsunomiya University Utsunomiya University Wonkwang University Wonkwang University

出版者

Published for the Research Institute for Fundamental Physics by Physical Society of Japan

雑誌

Progress of theoretical physics = Progress of theoretical physics (ISSN:0033068X)

巻号頁・発行日

vol.89, no.3, pp.679-696, 1993-03-25

被引用文献数

3

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We report on the characteristics of 9 bb^^- pair events produced by a 600 GeV/c π^- beam and detected in the hybrid emulsion spectrometer of Fermilab experiment E653. The measured lifetimes for samples of 12 neutral and 6 charged beauty hadrons are τ_<b^0>=0.81^<+0.34+0.08'>_<-0.22-0.02> ps, and τ_<b^±>=3.84^<+2.73+0.80>_<-1.36-0.16> ps.

著者

Shin Kawasoe Kazuki Ide Tomoko Usui Takuro Kubozono Shiro Yoshifuku Hironori Miyahara Shigeho Maenohara Mitsuru Ohishi Koji Kawakami

出版者

The Japanese Circulation Society

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

pp.CJ-18-0607, (Released:2018-09-27)

参考文献数

26

被引用文献数

7

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Background: The independent role of serum triglyceride (TG) levels as a cardiovascular risk factor is still not elucidated. We aimed to investigate if the effect of TG on arterial stiffness is influenced by the serum level of low-density lipoprotein cholesterol (LDL-C). Methods and Results: We studied 11,640 subjects who underwent health checkups. They were stratified into 4 groups according to LDL-C level (≤79, 80–119, 120–159, and ≥160 mg/dL). Arterial stiffness was evaluated by brachial-ankle pulse wave velocity (baPWV). In each group, univariate and multivariete logistic regression analyses were performed to investigate the association between high TG (≥150 mg/dL) and high baPWV (>1,400 cm/s). In the univarite analysis, high TG was significantly associated with high baPWV in LDL-C <79 mg/dL (OR, 3.611, 95% CI, 2.475–5.337; P<0.0001) and 80–119 mg/dL (OR, 1.881; 95% CI, 1.602–2.210; P<0.0001), but not in LDL-C 120–159 mg/dL and ≥160 mg/dL. In the multivariate analysis, high TG was significantly associated with high baPWV in LDL-C ≤79 mg/dL (OR, 2.558; 95% CI, 1.348–4.914; P=0.0040) and LDL-C 80–119 mg/dL (OR, 1.677; 95% CI, 1.315–2.140; P<0.0001), but not in LDL-C 120–159 mg/dL and ≥160 mg/dL. Conclusions: High TG and increased arterial stiffness showed an independent relationship in a Japanese general population with LDL-C ≤119 mg/dL. TG-lowering therapy might be an additional therapeutic consideration in these subjects.

著者

NOMOTO Shin

出版者

一般社団法人 日本オリエント学会

雑誌

Orient (ISSN:04733851)

巻号頁・発行日

vol.44, pp.19-39, 2009

被引用文献数

2

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The fourth/tenth (A.H./C.E.) century is one of the most crucial time to the development of Ismā'īlī Shī'ism not only because the Fāṭimids' claim for the sole leadership (<i>Imāmah</i>) conflicts with its original belief in the advent of the messianic figure called the Qā'im, but because some thinkers adopted Greek thought, especially Neoplatonism. This article aims at contributing to elucidation of how the Ismā'īlī thinkers made consistent their doctrine on the Qā'im with newly adopted Neoplatonism in this important century, with special reference to Abū Ḥātim al-Rāzī's (d. ca 322/933-4) <i>Kitāb al-Iṣlāḥ</i>, one of the oldest extant Neoplatonist-influenced texts.<br>&emsp;The text of <i>al-Iṣlāḥ</i> suggests that the Qā'im will resume the full contact, which Adam had enjoyed, with the two highest hypostases of Neoplatonist cosmology, that is, the Universal Intellect and the Universal Soul. Also in his text al-Rāzī implies that the advent of the Qā'im will mark or bring the full actualization of the "spiritual forms" (<i>al-ṣuwar al-rūḥānīyah</i>) and "simple form" (<i>al-ṣurah al-basīṭah</i>) of the human soul. This is also the result of the influence of the "highest simple world," the realm of the two highest hypostases. Thus, with the background of Greek thought, especially Neoplatonism, al-Rāzī de-politicized the role and mission of the Qā'im. This idea is shared by al-Sijistani (d. after 361/971), Neoplatonist Ismā'īlī thinker who is nearly one generation younger than al-Rāzī. Did this shared idea of the de-politicized and "spiritualized" Qā'im function as precursor for Ḥamīd al-Dīn al-Kirmānī's (d. after 411/1020) own vision of the Qā'im and the postponing of his advent and the ultimate <i>eschaton</i>? This will be an issue of our future research.

著者

Kazuhiro SHIN-IKE Hitoshi IIMA

出版者

The Society of Instrument and Control Engineers

雑誌

SICE Journal of Control, Measurement, and System Integration (ISSN:18824889)

巻号頁・発行日

vol.9, no.3, pp.144-150, 2016 (Released:2016-06-25)

参考文献数

11

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In this study, we propose a method for determining the classroom seating arrangements considering relationships between one student and the other students sitting around him or her. The method for determining the classroom seating arrangements is constructed based on our proposed genetic algorithm. In order to determine the optimal classroom seating arrangements, the genetic algorithm is applied on the basis of the questionnaire result of how students feel when they take a class on the seats assigned to them and the analysis of each student's personality. Experiments are carried out in order to verify the effectiveness of the proposed method.

著者

小山 信也 コヤマ シンヤ Shin-ya KOYAMA

出版者

東洋大学工業技術研究所

雑誌

工業技術 (ISSN:13499955)

巻号頁・発行日

no.32, pp.44-48, 2010

著者

竹田 新 Takeda Shin

出版者

大阪大学世界言語研究センター

雑誌

大阪大学世界言語研究センター論集 (ISSN:18835139)

巻号頁・発行日

no.1, pp.247-277, 2009

著者

申 琪榮 SHIN Ki-young

出版者

お茶の水女子大学ジェンダー研究所

雑誌

ジェンダー研究 = Journal of gender studies, Ochanomizu University : お茶の水女子大学ジェンダー研究所年報 (ISSN:13450638)

巻号頁・発行日

no.20, pp.121-124, 2017-03

著者

Kumekawa Yoshimasa Fujimoto Haruka Miura Osamu Yokoyama Jun Ito Katsura Tebayashi Shin-Ichi Arakawa Ryo Fukuda Tatsuya

出版者

首都大学東京小笠原研究委員会

雑誌

小笠原研究 = Ogasawara research (ISSN:03868176)

巻号頁・発行日

no.43, pp.1-17, 2017-06

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To clarify the morphological and phylogenetic differentiation of Bandona boninensis Suzuki 1974 in Chichi-jima Island of the Bonin (Ogasawara) group of Islands, we studied the external morphological characters and performed sequencing of the cytochrome c oxidase subunit I (COI) gene of mitochondrial DNA (mtDNA) and 28S rRNA of nuclear DNA (nrDNA). The sequences of COI and 28S rRNA were identical among the individuals of B. boninensis. These results suggest that B. boninensis experienced a rapid expansion of its distribution in Chichi-jima Island without undergoing any morphological and molecular differentiation.著者らは小笠原諸島の父島に生息するムニンカケザトウムシBandona boninensis の形態的および系統的分化を明らかにするために、父島の4 地点から採集を行い、体長、触肢腿節の長さ、背甲長および背甲幅、鋏角長、第1~4 脚の腿節長といった形態計測を実施し、ミトコンドリアDNA のCOI 領域および核DNA の28SrRNA 領域に基づく系統樹を作成した。その結果, ムニンカケザトウムシのCOI および28S において塩基置換は見られなかった。この結果は、ムニンカケザトウムシが父島内で系統的分化をほぼ起こしていないことを示す。また、採集を行った個体がすべて雌個体であったことから、これまでの報告の通り、父島においては単為生殖種として生息している可能性が高い。

著者

Brian Waters Kenji Hara Natsuki Ikematsu Mio Takayama Aya Matsusue Masayuki Kashiwagi Shin-ichi Kubo

出版者

日本法科学技術学会

雑誌

日本法科学技術学会誌 (ISSN:18801323)

巻号頁・発行日

vol.23, no.2, pp.125-131, 2018 (Released:2018-07-30)

参考文献数

19

被引用文献数

1

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The aim of this study was to develop a practical method to analyze tetrodotoxin (TTX), quantitatively, from postmortem specimens, not only blood and urine, but also organs. Extraction was achieved with 2% acetic acid and the use of an anion-exchange solid-phase extraction (SPE) cartridge. The quantitation method was a standard addition method with a calibration curve consisting of at least 3 points and an internal standard, voglibose (VOG). Separation by LC-MS/MS was achieved using a Luna HILIC (Phenomenex) column. The mobile phase was acetonitrile: 5 mM ammonium formate buffer (95:5), delivered at 0.2 mL/min. The selected reaction monitoring (SRM) transitions for TTX and VOG were m/z 320>302 and m/z 268>92, respectively. Cleaner extracts were achieved by using a lipid removal cartridge and washing with heptane. The addition of steps to remove interfering components that are prominent in postmortem samples aided in successful analysis. The HILIC column improved the retention of TTX to greater than 2 min to avoid the area where ion suppression has its greatest effect. Also, the use of anion-exchange SPE lessened the influence of acetic acid used during extraction. By using this method, we were able to quantitate low levels of TTX in postmortem specimens.

著者

Takamitsu TSUKAHARA Shin-ichi NAKAMURA Gustavo A. ROMERO-PÈREZ Makoto OHWAKI Takaharu YANAGISAWA Tatsuhiko KAN

出版者

BMFH Press

雑誌

Bioscience of Microbiota, Food and Health (ISSN:21863342)

巻号頁・発行日

vol.37, no.3, pp.49-57, 2018 (Released:2018-07-26)

参考文献数

57

被引用文献数

8

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It is well known dietary lactic acid bacteria (LAB) stimulates cell-mediated immunity such as natural killer (NK) activity in mice. Here, we aimed to assay the immunomodulatory effects of a cell preparation of Enterococcus faecalis strain KH-2 (CPEF). We further evaluated the possibility of antitumour activity caused by CPEF administration, because NK cells actively participate in the prevention of tumour formation. NK cell activity and gene expression of IFN-γ and Perforin 1, which were induced most likely by a synergetic action of their cytotoxic activity, were higher in splenocytes of CPEF-administered mice than they were in control mice. Moreover, unlike those of control mice, the splenocytes of CPEF-administered mice had significantly higher CD28+CD69+/CD4+ and CD28+CD69+/CD8+ ratios that resulted in a survival rate with a tendency toward improvement after 47 days of CPEF administration (p=0.1) in Meth-A fibrosarcoma-bearing mice. In conclusion, we showed that CPEF might be effective in treating Meth-A fibrosarcoma in mice, as it helped increase their survival rate via stimulation of an immune response in splenocytes, which involved systemic cellular immunity processes such as cytotoxic activity, and active T cells.

著者

Matsubara Masahiko Uozumi Takayuki Kotani Akio Harada Yoshihisa Shin Shik

出版者

一般社団法人日本物理学会

雑誌

Journal of the Physical Society of Japan (ISSN:00319015)

巻号頁・発行日

vol.71, no.1, pp.347-356, 2002-01-15

参考文献数

16

被引用文献数

38

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The polarization dependence of $2p \to 3d \to 2p$ resonant X-ray emission spectroscopy (RXES) in $3d^{1}$, $3d^{2}$ and $3d^{3}$ systems (TiF3, VF3 and Cr2O3, respectively) is measured and analyzed by means of the MX6 (M denotes a transition metal and X denotes a ligand, respectively) cluster model. The results are compared with a previous one for the $3d^{0}$ system (TiO2). Generally, with increasing $3d$ electron number, the spectral structure of RXES becomes more complicated by the influence of the crystal field and the multiplet coupling effect. Moreover, we point out that the selection rules on the polarization dependence of RXES change with the $3d$ electron number and that a drastic resonance enhancement corresponding to the excitation to an antibonding state in the $3d^{0}$ system is almost absent for the $3d^{n}$ systems with $n = 1$, 2 and 3.

著者

寳川 拓生 薮田 伸 冨永 淳 渡邉 健太 荒木 秀雄 川満 芳信 たからがわ ひろお やぶた しん とみなが じゅん わたなべ けんた あらき ひでお かわみつ よしのぶ Takaragawa Hiroo Yabuta shin Tominaga Jun Watanabe Kenta Araki Hideo Kawamitsu Yoshinobu 琉球大学農学部 不二製油

出版者

沖縄農業研究会

雑誌

沖縄農業 (ISSN:13441477)

巻号頁・発行日

vol.47, no.1, pp.27-34, 2015-02-12

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沖縄県においてヒマワリは景観の良さから観光資源として,さらには,地力回復用の緑肥として注目されている.そのヒマワリ栽培を油糧生産と遊休農地の解消の一助となると考え,播種期の違いが収量に与える影響について比較検討した.春播き栽培では,栽培期間中の気温,日射量,降水量,台風接近数および開花に要する積算温度が高く,発芽日から開花日までの日数が短かった.また,花芽形成期から開花期の間のCGRおよびLAIが低く,乾物収量,子実収量はそれぞれ705,177 kg 10a_-1と秋播き栽培に比べて低くなった.これは夏季の高温・高日射により栄養成長が不十分なまま開花し,子実肥大が遅れたことが原因と考えられた.一方,秋播き栽培では,花芽形成期から開花期までのCGRおよびLAIが高く,乾物収量,子実収量はそれぞれ1274,246 kg 10a-1と高かった.太陽エネルギー利用効率が植物体全体および子実に関してそれぞれ2.11,0.64%といずれも春播き栽培に比べて2倍以上高くなった.これは開花期までの成長期間と低温・低日射でも高い葉面積を確保できたことが原因と考えられた.以上より,沖縄においては,秋冬に降雪・降霜がなく,夏季の高温・高日射・台風を避けられるため,秋播き栽培も有用であると考えられた.

著者

IWAMOTO YUKIHIDE TANAKA KAZUHIRO ISU KAZUO KAWAI AKIRA TATEZAKI SHIN-ICHIRO ISHII TAKESHI KUSHIDA KAZUYOSHI BEPPU YASUO USUI MASAMICHI TATEISHI AKIO FURUSE KIYOO MINAMIZAKI TAKESHI KAWAGUCHI NORIYOSHI YAMAWAKI SHINYA

雑誌

Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association (ISSN:09492658)

巻号頁・発行日

vol.14, no.4, pp.397-404, 2009-07-01

参考文献数

22

被引用文献数

5

著者

Hiroyuki Tsutsui Shin-ichi Momomura Yoshihiko Saito Hiroshi Ito Kazuhiro Yamamoto Tomomi Ohishi Naoko Okino Toshihito Kitamura Weinong Guo

出版者

The Japanese Circulation Society

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

pp.CJ-17-1424, (Released:2018-07-26)

参考文献数

17

被引用文献数

15

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Background:The objective of the present analyses was to describe the baseline characteristics and treatment of the Japanese patients with HFrEF in THE PARALLEL-HF study.Methods and Results:Key demographic, clinical and laboratory findings, along with treatment, were reported and compared with patients enrolled in the PARADIGM-HF trial and other contemporary randomized clinical trials and registries of Japanese patients with HFrEF. In addition, the MAGGIC and EMPHASIS-HF risk scores were calculated. A total of 225 Japanese patients were randomized in PARALLEL-HF with a mean age of 67.9 years and the majority of the patients being male (85.8%) and in NYHA Class II (93.8%). Key baseline characteristics in PARALLEL-HF were generally comparable with PARADIGM-HF, and other contemporary clinical trials and registries of Japanese HFrEF patients. Patients enrolled in PARALLEL-HF were well treated with conventional evidence-based therapy at baseline (angiotensin-converting enzyme inhibitor inhibitor/angiotensin receptor blocker, 62.7%/37.3%; β-blockers, 94.7%; mineralocorticoid receptor antagonist, 59.1%). Despite the evidence-based treatment and most patients being in NYHA Class II, these patients had a low LVEF (mean 28.1%) and were at high risk of cardiovascular mortality and morbidity as assessed by the MAGGIC and EMPHASIS-HF risk scores.Conclusions:Overall, the patients in PARALLEL-HF were largely representative of contemporary ambulatory patients with HFrEF who are well treated with evidence-based therapies. PARALLEL-HF will determine whether sacubitril/valsartan provides similar improvements in clinical outcomes in Japanese HFrEF patients as observed in the PARADIGM-HF study.

著者

洞澤 伸 岡 江里子 ホラサワ シン オカ エリコ HORASAWA Shin OKA Eriko

雑誌

岐阜大学地域科学部研究報告 (ISSN:13428268)

巻号頁・発行日

no.19, pp.1-31, 2006-08-31

著者

Takashima Shin-ichiro Usui Soichiro Kurokawa Keisuke Kitano Teppei Kato Takeshi Murai Hisayoshi Furusho Hiroshi Oda Hiroyuki Maruyama Michiro Nagata Yoshiki Usuda Kazuo Kubota Koji Takeshita Yumie Sakai Yoshio Honda Masao Kaneko Shuichi Takamura Masayuki

出版者

BMJ Publishing Group

雑誌

Open Heart (ISSN:20533624)

巻号頁・発行日

vol.3, no.1, 2016-06-01

被引用文献数

4

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Objective: Comprehensive profiling of gene expression in peripheral blood leucocytes (PBLs) in patients with acute coronary syndrome (ACS) as a prognosticator is needed. We explored the specific profile of gene expression in PBLs in ACS for long-term risk stratification. Methods: 30 patients with ACS who underwent primary percutaneous coronary intervention (PCI) and 15 age-matched adults who participated in medical check-ups were enrolled from three centres. Peripheral blood samples were collected to extract RNA for microarray analyses. Results: During the 5-year follow-up, 36% of this cohort developed the expected non-fatal coronary events (NFEs) of target lesion revascularisation (TLR) and PCI for a de novo lesion. Class comparison analysis (p<0.005) demonstrated that 83 genes among 7785 prefiltered genes (41 upregulated vs 42 downregulated genes) were extracted to classify the patients according to the occurrence of NFE. Pathway analysis based on gene ontology revealed that the NFEs were associated with altered gene expression regarding the T-cell receptor signalling pathway in ACS. Univariate t test showed that the expression level of death-associated protein kinase1 (DAPK1), known to regulate inflammation, was the most significantly negatively regulated gene in the event group (0.61-fold, p<0.0005). Kaplan-Meier curve analysis and multivariate analysis adjusted for baseline characteristics or clinical biomarkers demonstrated that lower DAPK1 expression in PBL emerged as an independent risk factor for the NFEs (HR: 8.73; CI 1.05 to 72.8, p=0.045). Conclusions: Altered gene expression in T-cell receptor signalling in PBL in ACS could be a prognosticator for secondary coronary events. © Published by the BMJ Publishing Group Limited.

著者

Masahiro Nezu Masataka Kudo Ryo Morimoto Yoshikiyo Ono Kei Omata Yuta Tezuka Yasuhiro Igarashi Shin Hitachi Kei Takase Sadayoshi Ito Fumitoshi Satoh

出版者

The Japan Endocrine Society

雑誌

Endocrine Journal (ISSN:09188959)

巻号頁・発行日

pp.EJ18-0108, (Released:2018-07-13)

被引用文献数

1

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Acromegalic arthropathy is a common complication of acromegaly and harms the quality of life of the patients even after acromegaly is in long-term remission. A recent study demonstrated by knee MRI the characteristic structural features of acromegalic arthropathy. However, the effects of treatment for acromegaly on such structural features are almost unknown. This study was undertaken to analyze the effects of transsphenoidal surgery (TSS) on acromegalic arthropathy and elucidate whether knee MRI findings are reversible or irreversible. We analyzed 22 patients with acromegaly (63.7% females, median age 58 years) by knee MRI at diagnosis. Out of these 22 patients, 16 who underwent TSS (68.9% female, median age 58 years) were also subjected to knee MRI 2 months after TSS. As for X-ray undetectable findings, MRI detected synovial thickening, bone marrow lesion, ligament injury and meniscus injury in 22.7%, 22.7%, 4.7% and 59.1% of the patients, respectively. With respect to the 16 patients who underwent TSS, clinical and structural improvements were observed respectively in 100%, 66.7% and 66.7% of the patients who showed knee joint pain, synovial thickening and bone marrow lesion before TSS. However, no patient showed structural improvement of meniscus injury after TSS. In acromegalic arthropathy, synovial thickening and bone marrow lesions are reversible while meniscus injury is irreversible. Because all those findings are associated with the exacerbation of arthropathy, they may be therapeutic targets for preventing the progression of arthropathy by endocrinological and orthopedic intervention.

著者

伊丹 伸 福田 耕治 杉野 隆三郎 三宅 修平 Itami Shin Fukuda Koji Sugino Ryuzaburo Miyake Shuhei 阿南工業高等専門学校創造技術工学科 東京情報大学総合情報学部 Department of Creative Technology Engineering National Institute of Technology Anan College/ Faculty of InformaticsTokyo University of Information Sciences

巻号頁・発行日

vol.21(1), 2017-09-30

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生物の複雑な行動を定量化する手法の確立は,数理情報学の産業応用上重要な課題である.本研究では,カオス・フラクタル解析を用いて,光刺激に対する魚群の遊泳行動の定量化を試みる.試験魚は水産学上有益性の高いマアジとし,LEDによる光刺激は赤色・緑色・青色・白色と4種類の波長を与え,異なる光刺激に対する魚群行動パターンの相異をみるために実験を行った.水槽実験から取得した動画像データより,個々のマアジの遊泳軌跡を抽出して時系列データに変換,その群行動パターンの特徴量として最大リアプノフ指数とHiguchi法によるフラクタル次元を算出した.その結果,魚群行動の定量化に成功し,特に赤色時の遊泳行動にカオス・フラクタルによる特徴量の大きさの違いが確認できたことを報告する.

著者

岸田 広平 武部 匡也 石川 信一 キシダ コウヘイ タケベ マサヤ イシカワ シンイチ Kishida Kohei Takebe Masaya Ishikawa Shin-ichi

出版者

心理臨床科学編集委員会

雑誌

心理臨床科学 = Doshisha Clinical Psychology : therapy and research (ISSN:21864934)

巻号頁・発行日

vol.6, no.1, pp.3-16, 2016-12-15

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研究動向本論文の目的は,児童青年期の怒りに対する認知行動療法に関する展望を行うことであった。まず,児童青年期の怒りに関連する代表的な診断基準として,秩序破壊的・衝動制御・素行症群や抑うつ障害群について概観したうえで,怒りに関連した診断基準に最も近いものとして,重篤気分調節症が紹介された。次に,怒りに関連する代表的な理論として,学習理論,社会的情報処理モデル,ストレス相互作用説,認知モデルに関する説明を行った。さらに,それらの理論に基づく介入技法として,社会的スキル訓練,問題解決スキル訓練,自己教示訓練,リラクセーション,認知再構成法が紹介された。続いて,児童青年期の怒りに対するメタ分析の結果と代表的な治療プロトコルの概要が紹介された。その後,児童青年期の怒りに関する自己記入式のアセスメントの展望が行われた。最後に,児童青年期の怒りの問題点として,診断基準の洗練化,アセスメントにおける構成概念の混同,怒りに関連する認知的側面に関する基礎研究とそれに基づく介入の必要性が議論された。