著者

江口 和洋

出版者

日本鳥学会

雑誌

日本鳥学会誌 (ISSN:0913400X)

巻号頁・発行日

vol.65, no.2, pp.193-194, 2016 (Released:2016-11-22)

著者

音在 清輝 福島 昭三

出版者

公益社団法人 日本分析化学会

雑誌

分析化学 (ISSN:05251931)

巻号頁・発行日

vol.4, no.3, pp.188-193, 1955-05-05 (Released:2009-06-30)

参考文献数

16

著者

小川 真理子 Mariko OGAWA 東京工芸大学芸術学部基礎教育課程 Division of Liberal Arts and Science Faculty of Arts Tokyo Polytechnic University

雑誌

東京工芸大学芸術学部紀要 = Bulletin, Faculty of Arts, Tokyo Institute of Polytechnics (ISSN:13418696)

巻号頁・発行日

vol.14, pp.101-106, 2008

出版者

日本医史学会

巻号頁・発行日

vol.43(1), no.1485, 1997-03

著者

Nakazawa Daigo Masuda Sakiko Tomaru Utano Ishizu Akihiro

出版者

Springer Nature

雑誌

Nature reviews. Rheumatology (ISSN:17594790)

巻号頁・発行日

vol.15, no.2, pp.91-101, 2019-02

被引用文献数

259

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Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) affects systemic small vessels and is accompanied by the presence of ANCAs in the serum. This disease entity includes microscopic polyangiitis, granulomatosis with polyangiitis, eosinophilic granulomatosis with polyangiitis and drug-induced AAV. Similar to other autoimmune diseases, AAV develops in patients with a predisposing genetic background who have been exposed to causative environmental factors. The mechanism by which ANCAs cause vasculitis involves ANCA-mediated excessive activation of neutrophils that subsequently release inflammatory cytokines, reactive oxygen species and lytic enzymes. In addition, this excessive activation of neutrophils by ANCAs induces formation of neutrophil extracellular traps (NETs). Although NETs are essential elements in innate immunity, excessive NET formation is harmful to small vessels. Moreover, NETs are involved not only in ANCA-mediated vascular injury but also in the production of ANCAs themselves. Therefore, a vicious cycle of NET formation and ANCA production is considered to be involved in the pathogenesis of AAV. In addition to this role of NETs in AAV, some other important discoveries have been made in the past few years. Incorporating these new insights into our understanding of the pathogenesis of AAV is needed to fully understand and ultimately overcome this disease.

著者

Shoji Hemmi Katsumi Kurokawa Nana Izawa Yumiko Kutoku Tatsufumi Murakami Yoshihide Sunada

出版者

The Japanese Society of Internal Medicine

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

vol.50, no.7, pp.757-761, 2011 (Released:2011-04-01)

参考文献数

28

被引用文献数

6 5

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Neck dystonia is the most common cause of dropped head sign in parkinsonism. Isolated neck extensor myopathy, which is a rare condition, can also cause dropped head sign in parkinsonism, but no improvement has been achieved with immunosuppressive therapy. We report three cases of treatable neck extensor myopathy causing dropped head sign in patients with Parkinson's disease. Needle electromyography and magnetic resonance imaging suggested a restrictive active myopathy affecting neck extensor muscles. All cases responded dramatically to steroid therapy. Routine needle electromyography should be performed to explore treatable myopathy in Parkinson's disease.

著者

福田 泰久

出版者

愛知教育大学外国語外国文学研究会

雑誌

外国語研究 (ISSN:02881861)

巻号頁・発行日

vol.51, pp.61-76, 2018-03-31

著者

岡村 民夫 オカムラ タミオ Tamio Okamura

雑誌

立教大学フランス文学

巻号頁・発行日

vol.26, pp.1-24, 1997-03-25

著者

中川 浩一

出版者

日本社会科教育学会

雑誌

社会科教育研究 (ISSN:09158154)

巻号頁・発行日

vol.1968, no.27, pp.35-42, 1968 (Released:2016-12-01)

被引用文献数

1

著者

高野 博行 馬場 順昭

出版者

一般社団法人 日本航空宇宙学会

雑誌

日本航空宇宙学会誌 (ISSN:00214663)

巻号頁・発行日

vol.47, no.547, pp.117-121, 1999-08-05 (Released:2019-04-09)

参考文献数

6

出版者

公共建築協会

巻号頁・発行日

vol.28(3), no.112, 1986-12

出版者

シビル社

巻号頁・発行日

vol.6, no.9, 1927-09

出版者

公共建築協会

巻号頁・発行日

vol.20(1), no.79, 1978-06

著者

Hikaru Matsumoto Yoshinori Ikoma

出版者

The Japanese Society for Horticultural Science

雑誌

The Horticulture Journal (ISSN:21890102)

巻号頁・発行日

pp.UTD-364, (Released:2022-05-19)

被引用文献数

3

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Combined treatment with gibberellin (GA) and prohydrojasmon (PDJ) is effective at reducing peel puffing in satsuma mandarin (Citrus unshiu Marc.). However, the effect of this treatment on volatiles remains unknown. In satsuma mandarin, dimethyl sulfide (DMS) is a key flavor compound. In this study, the effects of combined treatment with GA and PDJ on the content of volatiles, DMS, and S-methylmethionine (SMM), a precursor of DMS, in the juice sacs of satsuma mandarin were investigated. Mixtures of GA (1, 3.3, or 5 mg·L−1) and PDJ (25 or 50 mg·L−1) were applied to ‘Okitsu-wase’ and ‘Aoshima’ in mid-September. Gas chromatography-mass spectrometry analysis showed that among the volatiles, DMS content was reduced by the treatment, and was below the DMS odor threshold in several treatments. In ‘Okitsu-wase’, the DMS content in treated fruit was 1/3 to 1/17 of the control. In the treatment with GA and 50 mg·L−1 PDJ, a reduction in DMS content was observed until mid-November, irrespective of GA concentration, whereas in the treatment with 1 mg·L−1 GA and 25 mg·L−1 PDJ, the reduction was observed only until early November. In ‘Aoshima’, the DMS content was also reduced by the treatments, but in the treatment with 1 mg·L−1 GA and 50 mg·L−1 PDJ, the reduction was observed only until mid-November. Although the applied treatments delayed color development by approximately 1–2 weeks, this delay was not related to a reduction in DMS content. The effects on SMM and methionine content were small or negligible. As DMS has a strong odor, with trace amounts affecting fruit flavor, controlling DMS content is important. This study revealed that combined treatment with GA and PDJ reduced the accumulation of DMS in the juice sacs of satsuma mandarin fruits.

著者

Kohei Mochida Akira Nakatsuka Tetsuya Kako Nobuo Kobayashi

出版者

The Japanese Society for Horticultural Science

雑誌

The Horticulture Journal (ISSN:21890102)

巻号頁・発行日

pp.UTD-366, (Released:2022-04-15)

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Tree peony (Paeonia spp.) is a highly ornamental shrub originally from China. Its cultivars are classified into four groups: Chinese, Japanese, French, and American, based on morphological characteristics and geographic location. The French and American cultivars were developed by crossing the wild species P. lutea Delavay ex Franch. and P. delavayi Franch. with Japanese and Chinese cultivars. In this study, we evaluated phenetic relationships among major cultivar groups in the genus Paeonia L., using a dendrogram reconstructed from band pattern data for random amplified polymorphic DNA (RAPD) markers developed in a previous study. We also developed two sequence tagged site (STS) markers using RAPD markers specific to the French and American tree peony cultivar groups and an intersubgeneric hybrid. The former is an LuDeB marker able to detect the genetic relationship with P. lutea and P. delavayi, and the latter is an HPB marker able to identify the cpDNA of herbaceous peony in intersubgeneric hybrid cultivars between herbaceous and tree peony. The possession of bands obtained in this study also supported the breeding history of cultivar development in the genus Paeonia.

出版者

公共建築協会

巻号頁・発行日

vol.2(2), no.5, 1959-05

著者

及川 正明

出版者

日本家畜臨床学会 ・ 大動物臨床研究会

雑誌

日本家畜臨床学会誌 (ISSN:13468464)

巻号頁・発行日

vol.30, no.1, pp.21-22, 2007-04-30 (Released:2009-04-22)

著者

栗原 可南子 藤岡 伸助 三嶋 崇靖 今野 卓哉 関 守信 坪井 義夫

出版者

日本神経学会

雑誌

臨床神経学 (ISSN:0009918X)

巻号頁・発行日

pp.cn-001686, (Released:2021-12-18)

参考文献数

14

被引用文献数

4

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パーキンソン病(Parkinson’s disease,以下PDと略記)に伴う非運動症状は患者の生活の質に与える影響が強く,疼痛はその中でも頻度が高い.今後治療エビデンスを確立するうえで疼痛を的確に評価することは,重要な課題である.2015年にPDの疼痛に特異的な評価スケールとしてKing’s Parkinson’s Disease Pain Scale(KPPS)が報告され,評価者ベースのKPPSに対応して2018年に患者ベースの質問票であるKing’‍s Parkinson’‍s Disease Pain Questionnaire(KPPQ)が報告された.今回我々は,KPPSとKPPQの言語的妥当性を担保した日本語版を作成した.

著者

戸田 勝哉

巻号頁・発行日

2010-11-29

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首都大学東京, 2010-03-25, 博士(工学)

著者

滝口修造 著

出版者

春鳥会

巻号頁・発行日

1937