著者
Tomonori Itoh Ken'ichi Fukami Tomomi Suzuki Takumi Kimura Yoshinori Kanaya Makoto Orii Iwao Goto Hiroki Matsui Shoma Sugawara Satoshi Nakajima Tetsuya Fusazaki Motoyuki Nakamura for the IMPORTANT investigators
出版者
The Japanese Circulation Society
雑誌
Circulation Journal (ISSN:13469843)
巻号頁・発行日
pp.1006100756, (Released:2010-06-19)
参考文献数
27
被引用文献数
11 13

Background: Acute efficacy and long-term prognostic differences between ST-elevation myocardial infarction (STEMI) patients treated with primary percutaneous coronary intervention (primary PCI) and those treated with pre-intervention thrombolysis combined with back-up of facilitated PCI has not been evaluated in Japanese patients. The purpose of the present study was therefore to evaluate the differences between treatment with primary PCI (primary-PCI group) and pre-treatment with tissue-type plasminogen activator (t-PA) combined with back-up of facilitated PCI (prior-t-PA group). Methods and Results: One hundred and one patients with STEMI were randomly assigned to 2 groups. Patients in the prior-t-PA group were then divided into 2 further groups, the facilitated-PCI and prior-t-PA alone groups. The patency rate at initial angiography, left ventricular ejection fraction (LVEF) at 6 months, and the major adverse cardiac event (MACE)-free rate at 5 years were then compared between the groups. The patency rate and LVEF in the prior-t-PA group was significantly higher than in the primary-PCI group (69% vs 17% respectively, P<0.001; 61.6±9.5% vs 55.0±11.6%, respectively; P=0.01). The MACE-free rate in the prior-t-PA group, however, was lower than in the primary-PCI group (58.7% vs 80.9%; P=0.03). The MACE-free rate in the facilitated-PCI group was equal to that in the primary-PCI group (73.7% vs 80.9%; P=0.39), whereas the MACE-free rate in the prior-t-PA-alone group was significantly lower than in the primary-PCI group (48.1% vs 80.9%; P=0.01). Conclusions: Primary PCI is superior to pre-intervention thrombolysis for long-term prognosis. Moreover, facilitated PCI may be as effective as primary PCI in patients with STEMI.
著者
田村 高志
出版者
医学書院
巻号頁・発行日
pp.650-651, 2002-07-01

性染色質とは 1949年,BarrとBertramは雄ネコの神経細胞休止核には見られないが,雌ネコの細胞核周辺部に塩基性色素に濃染する小体を発見した1).また,ヒト女性口腔粘膜細胞などにもこの小体がみられ,これを性染色質(sex chromatin)あるいは発見者の名にちなんでバー小体(Barr body)とも呼んでいる.性染色質は,後に蛍光色素による男性休止核にみられるYクロマチンが発見されたため,Xクロマチンと呼ぶように改められ,XクロマチンとYクロマチンとを総称したものになった.性染色質検査は性染色体異常のスクリーニング検査として行われている. 現在,性別の確認はSRY遺伝子やXとY染色体上に座位するアメロゲニン遺伝子をPCR(polymerase chain reaction)法によって検出することで正確な鑑別が可能である.これらは法医学領域,異性間骨髄移植後の生着の確認やオリンピックなどのスポーツ大会でのセックスチェックに応用されている.
著者
卜部 信行
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.78, no.8special2, pp.1731-1745, 1985-08-24 (Released:2011-11-04)
参考文献数
32

Cases of tinnitus totaling up to 163 examined at the Oto-Rhino-Laryngological Clinic of Tottori University Hospital have been reviewed. They consisted of 78 men and 85 women aged from 15 to 84 years. Tinnitus was attempted to be expressed verbally by onomatopoeia. The most frequent expression was “geen” [d i n]. Pitch matching and loudness matching tests were carried out in 146 patients. The most frequently observed pitch and loudness of tinnitus was 8000Hz and 0dB HL., respectively. The masking curve examined by bands of noise showed 7 types, including the convergence type (42% of 77 cases). Residual inhibition (RI) was studied by 1-min delivery of bands of noise in 82 cases, in 58 of which RI was positive. Effects of i. v. injected lidocaine (60mg for males, 40mg for females) were examined in 121 cases: tinnitus disappeared entirely in 39 cases; and was reduced partially in 53. The i. v. injected agent was effective in most of the RI-positive cases. To sum up these findings and ones obtained by auditory brain-stem response examination, suppression of tinnitus by RI and i. v. injected lidocaine may result from participation in the brain stem.
著者
HIROSHI TAZAKI NAOAKI IKEDA SHUZABURO OMORI
出版者
The Keio Journal of Medicine
雑誌
The Keio Journal of Medicine (ISSN:00229717)
巻号頁・発行日
vol.13, no.3, pp.143-154, 1964 (Released:2009-03-27)
参考文献数
31
被引用文献数
3 4

A case of true hermaphroditism was reported, in which bilateral ovotestes were found, drumstick was positive in 12 out of 500 polymorphous leukocytes of peripheral blood stream, and the chromosome karyotype was 46 XX.Fifty cases of true hermaphrodites reported in Japan were reviewed and briefly discussed.Grateful acknowledgement is made to Prof. H. Tamura, Assistant Prof. H. Tofukuji of Dept. of Urology, and Assistant Prof. H. Watanabe of Dept. of Pathology. Our thanks are also to Dr. K. Suzuki of Dept. of Urology.Our grateful acknowledgements are due to Dr. Akira Tonomura in the Dept. of Human Genetics, National Institute of Genetics, Mishima, Japan.

1 0 0 0 OA 〓の研究

著者
梶山,英二
出版者
東京動物學會
雑誌
動物学雑誌
巻号頁・発行日
vol.26, no.305, 1914-03-15
著者
王 勇
出版者
国際日本文化研究センター
巻号頁・発行日
pp.1-29, 1994-11-05

会議名: 日文研フォーラム, 開催地: 国際交流基金 京都支部, 会期: 1992年9月8日, 主催者: 国際日本文化研究センター
著者
薊 理津子
雑誌
江戸川大学紀要 = Bulletin of Edogawa University
巻号頁・発行日
vol.29, 2019-03-15

本研究では,屈辱感が社会適応的行動を促進する,云わば,自己を向上させる行動を導くための調整変数を検討することを目的とした。調整変数として,自己効力感,Locus of Control,達成動機,賞賛獲得欲求,拒否回避欲求,自尊感情,原因帰属を取り上げた。先行研究に基づき,自己が他者よりも劣位に置かれた場面に焦点をあて,大学生にとって想起しやすいゼミのレポートの評価というシナリオを設定して検討した。結果,賞賛獲得欲求の低い者は屈辱感が高まると,自己を向上させる行動が促された。また,内的帰属の低い者は屈辱感が高まると,自己を向上させる行動が促されることが示された。以上より,自己が他者よりも劣位に置かれるという場面において,屈辱感が自己向上を動機づけるよう導く調整変数として,賞賛獲得欲求と内的帰属が見出された。
著者
Mana Kogure Naho Tsuchiya Akira Narita Takumi Hirata Naoki Nakaya Tomohiro Nakamura Atsushi Hozawa Takehito Hayakawa Nagako Okuda Naoko Miyagawa Aya Kadota Takayoshi Ohkubo Yoshitaka Murakami Kiyomi Sakata Katsuyuki Miura Akira Okayama Tomonori Okamura Hirotsugu Ueshima
出版者
Japan Epidemiological Association
雑誌
Journal of Epidemiology (ISSN:09175040)
巻号頁・発行日
pp.JE20190234, (Released:2020-02-08)
参考文献数
20
被引用文献数
4

Background: Major reasons for long-term care insurance certification in Japan are stroke, dementia and fracture. These diseases are reported to be associated with calcium intake. This study examined the association between calcium intake and impaired activities of daily living (ADL) using the data from NIPPON DATA90, consisting of representative sample of the Japanese population.Methods: A population-based nested case control study was performed. A baseline survey was conducted in 1990, followed by ADL surveys of individuals ≥65 years old in 2000. Individuals with impaired ADL and selected age- and sex-matched controls were then identified. We obtained 132 pairs. Calcium intake was energy-adjusted using the residual method. The association between calcium intake and impaired ADL was examined using conditional logistic regression models. To assess the accuracy of the estimates, we conducted bootstrap analyses.Results: The adjusted odds ratios (ORs) for impaired ADL compared with the group with a calcium intake of <476 mg/day were 0.72 (95% confidence interval, 95% CI: 0.37-1.40) for the 476-606 mg/day group and 0.44 (0.21-0.94) for the ≥607 mg/day group in 2000 (P for linear trend = 0.03). After the bootstrap analyses, the inverse relationship unchanged (median OR per 100-mg rise in calcium intake: 0.87 [1,000 resamplings], 95% CI: 0.76-0.97).Conclusions: After bootstrap analyses, calcium intake was inversely associated with impaired ADL, 10 years after the baseline survey.
著者
橋野 領太
出版者
地域農林経済学会
雑誌
農林業問題研究 (ISSN:03888525)
巻号頁・発行日
vol.54, no.3, pp.141-148, 2018-09-25 (Released:2018-09-29)
参考文献数
24

Tariffs, export subsidies, and income supports are major examples of agriculture protection by developed countries. However, comparing the revealed trade advantage and nominal rate of assistance, there is no clear evidence that protection affects trade. Therefore, this study examines the impact of agricultural protection policies on agricultural competitiveness using a fixed effect model with panel data of 76 countries worldwide. The empirical results show that agricultural protection policies do influence agricultural competitiveness. In addition, as mentioned in several studies, the land-labor ratio and average wage partially regulate agricultural competitiveness. The empirical results suggest that agricultural protection policies do reduce trade volume and can cause economic inefficiency at the same time.
著者
Xing-Bing Pan Hui-Jun Wang Bing Zhang Ying-Li Liu Su-Fen Qi Qing-Bao Tian
出版者
Japan Epidemiological Association
雑誌
Journal of Epidemiology (ISSN:09175040)
巻号頁・発行日
vol.30, no.3, pp.128-135, 2020-03-05 (Released:2020-03-05)
参考文献数
32
被引用文献数
8

Background: The prevalence of overweight is increasing dramatically worldwide. The aim of our study was to investigate the association of plain water intake (PWI) with the risk of new-onset overweight risk among Chinese adults.Methods: A total of 3,200 adults aged 18–65 who were free of overweight at baseline were enrolled from China Health and Nutrition Survey (CHNS) cohort study in 2006–2011. The risk of new-onset overweight with different amounts of PWI per day was analyzed in this 5-year cohort. A multiple logistic regression model was used to assess the association of PWI and the risk of new-onset overweight and adjust for potential confounders. Moreover, dose-response models were developed to estimate the linear relationship.Results: During 5 years of follow-up, 1,018 incident cases were identified. Our analysis indicated an inverse association of more than 4 cups of PWI per day and the risk of new-onset overweight among normal weight individuals. Compared with participants who drank 2 to 3 cups PWI, the adjusted odds ratios (OR) of overweight were 0.741 (95% confidence interval [CI], 0.599–0.916) in participants who drank 4 to 5 cups PWI, and 0.547 (95% CI, 0.435–0.687) in participants who drank more than 6 cups PWI. The dose-response analysis showed that every cup of PWI was associated with a 6.5% and 8.4% decrease in the risk of new-onset overweight among men and women, respectively. The interactions of PWI and covariates on the risk of overweight were not found.Conclusion: Drinking more than 4 cups (≈1 liter) per day of plain water is associated with decrease in the risk of new-onset overweight among normal-weight individuals.

1 0 0 0 OA 亡国星

著者
松居松葉 著
出版者
春陽堂
巻号頁・発行日
1900