著者
北原 糺 村田 潤子 小畠 小畠 奥村 新一 江崎 光彦
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.91, no.8, pp.845-849, 1998-08-01 (Released:2011-11-04)
参考文献数
11

In this paper, a very rare case of vasculo (angio)-Behcet's disease initiated with hoarseness due to inflammatory aortic aneurysm, is presented. A 35 year-old male with persistent hoarseness for half a month was revealed to have left recurrent laryngeal nerve palsy. Chest X-ray films showed slight enlargement of the aortic arch. CT demonstrated direct evidence of a saccular type aortic aneurysm at the branched area of the left subclavian artery. Aortic angiography demonstrated two additional aortic aneurysms at the right subclavian artery and in the lower abdominal area. The patient subsequently underwent emergency surgery for treatment of these aneurysms. The histopathological characteristics of the representative aortic aneurysmal lesions suggested a diagnosis of “vasculo-Behcet's disease”. Behcet's disease is usually characterized by oral and genital ulceration, folliculitis and uveitis. This patient, however, displayed no previous evidence of these symptoms. We would like to emphasize that some cases of left recurrent laryngeal nerve palsy require urgent management.
著者
近藤 律男 榎本 浩幸 田口 享秀 長原 太郎 佃 守
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.98, no.4, pp.309-313, 2005-04-01 (Released:2011-10-07)
参考文献数
21
被引用文献数
1

Behçet's Disease is a systemic disease characterized by mucosa, dermis and eye lesions. Otolaryngologists sometimes examine patients of this disease who complain of inveterate aphthae. Patients with Behçet's Disease often have histories of tonsillitis and many caries of the tooth. Based on these facts, streptococcus in the oral cavity is suspected to be closely related to this disease.We report a case of Behçet's Disease whose first symptom was acute tonsillitis.A 33-year-old male complaining of sore throat and elevated fever was referred to our hospital. Oral aphthae was seen and the bilateral palatine tonsils were swollen, reddish and coated with fur. We diagnosed acute tonsillitis and treated him with antibiotics. However, elevated fever, inflammation and oral aphthae were not remitted and a pudendal ulcer appeared. We suspected Behçet's Disease and consulted with doctors of internal medicine, dermatology and ophthalmology. Fourteen days after admission, folliculitis and arthritis appeared and finally he was diagnosed with incomplete type Behçet's Disease.This case suggests that tonsillitis is closely related with the appearance of Behçet's Disease. Furthermore, oral aphthae and tonsillitis are very important symptoms regarding Behçet's Disease, in patients with oral aphthae.
著者
野上 晃司 應田 義雄 松本 譽之
出版者
一般社団法人 日本消化器内視鏡学会
雑誌
日本消化器内視鏡学会雑誌 (ISSN:03871207)
巻号頁・発行日
vol.54, no.9, pp.3115-3123, 2012 (Released:2012-10-22)
参考文献数
12
被引用文献数
2

ベーチェット病は再発性口腔内アフタ,皮膚症状,眼症状,外陰部潰瘍を4主症状とする難治性の全身炎症性疾患である.さらに5つの副症状として関節炎,副睾丸炎,血管炎,消化管症状,中枢神経症状があげられる.消化管ベーチェット病は,この副症状のひとつである消化管症状が主に出現しているものをいう.ベーチェット病の消化管病変は全消化管に生じうるが,好発部位は回盲部近傍で,典型例では難治性の深い下掘れ傾向をもつ打ち抜き潰瘍を呈する.診断では,これらと同様の粘膜所見を来す疾患を鑑別することが重要である.臨床経過や,それぞれの粘膜所見の類似点・相違点に着目し疾患を除外していく.治療に関しては,依然確立されていないが,抗TNF-α抗体製剤の有用性が認められつつある.
著者
進 武幹 福山 つや子
出版者
日本口腔・咽頭科学会
雑誌
口腔・咽頭科 (ISSN:09175105)
巻号頁・発行日
vol.5, no.2, pp.37-41, 1993-03-31 (Released:2010-06-28)
参考文献数
9

The cause of Behcet's disease is still unknown. In this paper, we describe the features of Behcet's disease as reported by the Japan Ministry of Health and Welfare in 1987. Behcet's disease is characterized by oral and genital ulcers and ocular inflammation. At least two of these main symptoms are required to establish the diagnosis. Behcet's disease is further classified as having mucocutaneous, arthritic, digestive, vascular and neurologic abnormalities.Behcet's disease must be differentiated from benign mucous membrane pemphigus, pemphigoid and erythema multiforme. The ulcers in recurrent aphthous stomatitis are quite similar in appearance. These diseases can be ruled out with pathological and immunological techniques.
著者
阪本 ゆり 浅井 睦代 杉原 和子 織田 知明 荒金 兆典 川田 暁 手塚 正
出版者
Meeting of Osaka Dermatological Association
雑誌
皮膚 (ISSN:00181390)
巻号頁・発行日
vol.42, no.3, pp.305-309, 2000 (Released:2010-08-25)
参考文献数
9

47歳男性で神経ベーチェット病と考えられた1例を報告した。既往に10年間口腔内アフタと陰部潰瘍を繰り返していた。発熱, 右眼の複視, 口腔内アフタ, 陰部潰瘍を主訴に当科に入院し, 精査を行なった。神経学的には右外転神経麻痺による複視, 髄液検査で細胞数の増加がみられた。脳MRl所見で橋部においてT1強調画像の低信号域, T2強調画像の高信号域, 造影剤の増強効果が認められ, 橋部の炎症所見が示唆された。プレドニン内服によって皮膚症状と神経症状は著明に改善し, またMRI所見も改善が認められた。重篤な後遺症も認めなかった。自験例では脳MRI所見が神経症状の早期診断と治療効果の判定に有用であった。
著者
Takashi Maruyama Eriko Tomokiyo Junji Maeda
出版者
水文・水資源学会/日本地下水学会/日本水文科学会/陸水物理研究会
雑誌
Hydrological Research Letters (ISSN:18823416)
巻号頁・発行日
vol.4, pp.40-44, 2010 (Released:2010-04-09)
参考文献数
4
被引用文献数
1 4

The strong wind field caused by Typhoon Songda, which passed through Kyushu in Japan in 2004, was simulated numerically. A non-hydrostatic mesoscale model was used for the numerical simulation. The simulated wind field was compared with the observed wind field in terms of wind speeds and directions, which were measured by the wind observation network, NeWMeK. It was found that the temporal variation of the calculated wind speeds at 1 km hori-zontal mesh grids correspond to the average of the observed wind speeds over a ten to fifteen minute time period. The temporal variation of the calculated wind directions showed good agreement with the observations. The maximum values of the calculated wind speeds were highly correlated to the maximum values of the observed wind speeds. The applicability of the mesoscale model for the wind hazard assessment of buildings was examined, and it was found that the maximum values of the calculated wind speeds at higher altitudes showed higher correlations with the rates of damaged houses caused by Typhoon Songda.
著者
Johann Plank Bernhard Sachsenhauser
出版者
公益社団法人 日本コンクリート工学会
雑誌
Journal of Advanced Concrete Technology (ISSN:13473913)
巻号頁・発行日
vol.4, no.2, pp.233-239, 2006 (Released:2006-06-30)
参考文献数
15
被引用文献数
32 106

α-Allyl-ω-methoxypolyethylene glycol - maleic anhydride copolymers were synthesized with side chain lengths nEO from 0-130 and characterized by aqueous GPC. A representation of their molecular conformation (e.g. worm-, brush- or star-like polymers) was developed. The amount of polymer adsorbed on cement rapidly decreases with increasing side chain length nEO. Zeta potential measurements using the electroacoustic method in cement paste with w/c = 0.5 indicate that worm-like copolymers with nEO ≤ 7 adsorb flat (“train” type) and form a densely packed, thin polymer film. In this case, the adsorbed amount of copolymer is high. For star polymers with nEO ≥ 34, preferred orientation of the polymer main chain is perpendicular to the cement surface (“tail” type). The result is a thick polymer layer, with a second electrochemical double layer on top. For star polymers, the adsorbed amount is low because of the higher surface occupancy of horizontally layered side groups.
著者
Nobuo TAKAHASHI
出版者
グローバルビジネスリサーチセンター・東京大学MERC
雑誌
Annals of Business Administrative Science (ISSN:13474464)
巻号頁・発行日
vol.12, no.5, pp.237-250, 2013-10-15 (Released:2013-10-15)
参考文献数
18
被引用文献数
11 14

Japanese companies often criticize themselves on their own “nurumayu [lukewarm] nature.” Takahashi (1989) states that, in reality, however, the lukewarm feeling felt by organization members can be explained through the effective temperature hypothesis. The organization's propensity to change as a system is measured as system temperature, while the member's propensity to change as an organization person is measured as body temperature. The lukewarm feeling that the member feels can be explained using effective temperature, which is defined as the system temperature minus the body temperature. The effective temperature hypothesis was tested using the JPC Survey conducted every year from 1990 to 2000, where N = 10,356. The results show the coefficient of determination of 0.9886 with a surprisingly neat straight line, demonstrating a direct relationship wherein the lukewarm feeling ratio drops as the effective temperature rises. This paper also shows the possibility that the lukewarm feeling and effective temperature are leading indicators of the economic recession.
著者
Fumihiko IKUINE Hideki FUJITA
出版者
グローバルビジネスリサーチセンター・東京大学MERC
雑誌
Annals of Business Administrative Science (ISSN:13474464)
巻号頁・発行日
vol.12, no.5, pp.251-263, 2013-10-15 (Released:2013-10-15)
参考文献数
24
被引用文献数
2 2

It is difficult to identify easily adaptable software in its completed form. In its nature, the definition of “complete” is unclear. As a result, if one expects perfection in software, software products will never be released; the only alternative is to release software if it runs, and then gradually refine it over time. This results in the implicit conventional wisdom that the “continuous development” of the software is the best quality assurance. This paper looks at the highly capable Windows e-mail software called “Hidemaru Mail.” With current progress in IT, it is possible that the concept of software quality assurance can be applied to a broader array of products and services.
著者
Kenichi KUWASHIMA
出版者
グローバルビジネスリサーチセンター・東京大学MERC
雑誌
Annals of Business Administrative Science (ISSN:13474464)
巻号頁・発行日
vol.12, no.5, pp.265-276, 2013-10-15 (Released:2013-10-15)
参考文献数
21
被引用文献数
1

This paper suggests three footnotes regarding heavyweight product manager (HWPM). HWPM, a term coined by Fujimoto (1989), refers to powerful managers that act as both internal and external integrators. Footnote 1: Fujimoto (1989) used the term “product manager” for project managers responsible for product development to emphasize their long-term and wide range of responsibilities and authority, which continue even after the completion of a product development project. Footnote 2: The list of internal integration index and external integration index used to measure HWPM and the organizational variables that comprise the two are given in the Appendix of Clark and Fujimoto (1991). However, the organizational variables noted as composition factors for these indices are misprints. In fact, it is necessary to reverse the organizational variables that refer to the indices. Footnote 3: Based on their empirical study, Clark and Fujimoto (1991) classify the following two cases as “lightweight product manager structures.” First is one in which “the degree of internal integration is high while that of external integration is low,” and second is when “the degree of internal integration is low while that of external integration is high.” However, the two product development organizations significantly differ. By classifying them, it is possible to glean deep insights into the relationship between the product development organization and product development performance.
著者
Hiroshi Matsuo Takashi Ogihara Hitoshi Aikiyo Shigenobu Yamanaka
出版者
Asian Electric Vehicle Society
雑誌
Journal of Asian Electric Vehicles (ISSN:13483927)
巻号頁・発行日
vol.7, no.2, pp.1333-1336, 2009 (Released:2010-01-29)
参考文献数
4
被引用文献数
1 1

The running test of railcar was examined using large lithium ion battery in the local line in Japan. 90 kWh of Mn type lithium ion battery was used. The relation between running time and voltage, current and integrating watt was investigated in detail. The railcar was run when the lithium ion battery module was discharged between 660 V and 480 V. The use of lithium ion battery had little voltage changes and enabled the smooth running compared with contact-wire type railcar. On one charge, it was also found from the running test that the railcar could run for about 40 km and the mileage improved 9 %. The running performance of lithium ion battery type railcar was equivalent to the contact-wire type railcar. It was found that the railcar powered by lithium ion battery was effective for the replace of diesel type railcar in the local line.
著者
Yan ZHANG Xiaoyan HUANG Wenfang LIU Zeneng CHENG Chuanpin CHEN Lihui YIN
出版者
(社)日本分析化学会
雑誌
Analytical Sciences (ISSN:09106340)
巻号頁・発行日
vol.29, no.10, pp.985-990, 2013-10-10 (Released:2013-10-10)
参考文献数
34
被引用文献数
3 24

Illegal chemicals, which could cause unpredictable side effects, may be added into traditional Chinese medicine (TCM) for a rapid healing effect. In this report, a surface-enhanced Raman scattering (SERS) analysis method for five kinds of illegally added drugs (rosiglitazone maleate, phenformin hydrochloride, metformin hydrochloride, pioglitazone hydrochloride and sibutramine hydrochloride) in Chinese traditional patent medicine (CTPM) has been demonstrated, including simultaneous detections of drug mixtures with CTPM. Silver colloidal, prepared by a sodium citrate reaction, was used as a SERS substrate. The optimum pH condition for each drug has also been explored because of its combined effect on protonation, surface charge, repulsion of an analyte and nanoparticles. Furthermore, the simultaneous detection of two or three kinds of these chemicals has been carried out. Characteristic peaks are employed for qualitative analysis. This is the first research using SERS for the analysis of drug mixtures in CTPM without any separation process.
著者
Takashi Watanabe
出版者
CODATA
雑誌
Data Science Journal (ISSN:16831470)
巻号頁・発行日
vol.8, pp.S102-S107, 2009-09-24 (Released:2009-09-24)
被引用文献数
4

This paper briefly reviews the activities of the International Council for Science (ICSU) World Data Centers (WDCs) in Japan at a time of great change in the data and information structures of the ICSU ? the creation of the World Data System (WDS) in 2009. Seven WDCs are currently operating in Japan: the WDC for Airglow, the WDC for Cosmic Rays, the WDC for Geomagnetism, Kyoto, the WDC for Ionosphere, the WDC for Solar Radio Emission, and the WDC for Space Science Satellites. Although these WDCs are highly active, along-term support system must be established to ensure the stewardship and provision of quality-assessed data and data services to the international science community.
著者
Yoji Urabe Hideya Yamamoto Toshiro Kitagawa Hiroto Utsunomiya Hiroshi Tsushima Fuminari Tatsugami Kazuo Awai Yasuki Kihara
出版者
日本循環器学会
雑誌
Circulation Journal (ISSN:13469843)
巻号頁・発行日
vol.77, no.10, pp.2578-2585, 2013 (Released:2013-09-25)
参考文献数
38
被引用文献数
11 16

Background: Intensive lipid-lowering therapy with statins reduces cardiovascular events, but residual cardiovascular risks remain. Intake of n-3 polyunsaturated fatty acids (PUFAs) has been associated with cardiovascular events. We examined the relationships between serum n-3 PUFAs and coronary atherosclerotic findings on computed tomography angiography (CTA) in patients undergoing statin treatment. Methods and Results: We enrolled 172 subjects (mean age: 68.2 years; 64% men) prior to statin treatment for 6 months. Serum PUFAs, including eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and arachidonic acid, were measured. When the patients were divided into 2 groups according to the median EPA level (61.3μg/ml), the low-EPA group showed higher incidences of 3-vessel plaque involvement (62% vs. 43%, P=0.015), noncalcified plaques (NCPs) (74% vs. 52%, P=0.0016), extensive NCPs (≥2 segments) (56% vs. 34%, P=0.0036), and high-risk plaques (minimum CT density <39HU and remodeling index >1.05) (43% vs. 22%, P=0.0034). Multivariate analyses revealed that low EPA levels were an independent factor for these coronary plaque findings. The DHA levels were not independently associated with these findings. Conclusions: Low serum EPA level, but not serum DHA, is associated with the presence and extent of NCPs and high-risk plaques detected by coronary CTA in patients undergoing lipid-lowering therapy with statins.  (Circ J 2013; 77: 2578–2585)
著者
荻 芳郎 川口 健一 大矢 俊治 片山 慎一朗 熊谷 祥吾 櫻井 重喜
出版者
日本建築学会
雑誌
日本建築学会技術報告集 (ISSN:13419463)
巻号頁・発行日
vol.16, no.33, pp.821-826, 2010-06-20 (Released:2010-06-18)
参考文献数
8
被引用文献数
2

Damage to non-structural components in large roof buildings, failed during the Iwate-Miyagi Nairiku Earthquake in 2008 or an earthquake in the north shore of Iwate prefecture in July 24th of 2008, is reported.The northeastern region of Japan had been hit by major earthquakes frequently in recent years. Nevertheless, the similar damage had been repeated, since the failed parts had been fixed and recovered always with no essential improvements.
著者
川口 健一 荻 芳郎 大矢 俊治 片山 慎一朗 熊谷 祥吾 櫻井 重喜
出版者
東京大学生産技術研究所
雑誌
生産研究 (ISSN:0037105X)
巻号頁・発行日
vol.60, no.6, pp.541-554, 2008 (Released:2009-02-13)
参考文献数
2
被引用文献数
1

2008年に東北地方で発生した2回の大きな地震, 「岩手・宮城内陸地震」及び「岩手県沿岸北部地震」, がもたらした, 大規模集客施設における非構造材の被害に関して, 我々の研究室で行った現地調査の結果について報告する.特に天井を中心とする非構造材の落下被害の観察された9施設について被害概要を報告する.東北地方は繰り返し地震被害にあっているが, 施設の復旧は原状復帰が主であり, 同じ被害を繰り返している.過去の地震被害の教訓が生かされていない実状がはっきりと分かった.[本要旨はPDFには含まれない]
著者
原田 一雄 児玉 秀臣
出版者
Japan Association of Mineralogical Sciences
雑誌
岩石鉱物鉱床学会誌 (ISSN:00214825)
巻号頁・発行日
vol.49, no.3, pp.115-118, 1963-03-05 (Released:2008-08-07)
参考文献数
6

A new occurrence of freibergite from the Chichibu Mine is described. The freibergite, which was found from the upper part of the Daikoku ore deposits, associated with pyrite, euhedral crystal of chalcopyrite, bornonite, ankerite and quartz. Mineralogical properties of the mineral are as follows; 1. euhedral, tetrahedral crystal about 1cm in diameter. 2. streak color, reddish brown. 3. ao=10.435A. 4. the spectrochemical analysis shows the presence of the major amounts of Cu, Ag and Sb, minor amounts of Fe, As and Si, and trace of Zn, Pb and Cd.