著者

Shohei TAKAOKA Tsutomu KAIZUKA Bo YANG Kimihiko NAKANO

出版者

The Japan Society of Mechanical Engineers

雑誌

Mechanical Engineering Journal (ISSN:21879745)

巻号頁・発行日

vol.7, no.2, pp.19-00572, 2020 (Released:2020-04-15)

参考文献数

28

被引用文献数

1

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Methods for presenting information by utilizing a visual field (such as driver peripheral vision) are attracting increased attention in association with an increase in the amount of information required for driver assistance. However, studies on interfaces utilizing such a visual field are currently insufficient. In addition, to avoid information overload, it is important to evaluate different interfaces in terms of the amount of information presented. The authors researched those interfaces from the viewpoint of ergonomics with the purpose that the result is possible to be applied to various researches mainly in the field of automobiles. Through an in-house experiment, participants viewed video clips presenting dot patterns within their peripheral vision or effective visual field (which is nearer to the gazing point than peripheral vision), and then answered questions regarding the positions and moving directions of the dots and the mental workload they experienced. The authors prepared two types of dotted patterns (fixed and moving) based on the perceptive characteristics of peripheral vision. The number of dots varied from one to six. The rate of misperception and participant mental workload were calculated. The results showed a tendency for the effect of the visual fields to depend on the type of dot pattern. It appears that the interface for peripheral vision may have resulted in a lower accuracy when fixed objects were presented, whereas fewer differences occurred when moving dots were shown. This implies that information with motion can be more suitable for interfaces utilizing peripheral vision. A larger amount of information and number of tasks resulted in lower accuracy and higher workload. Moreover, the relation between the number of dots and the rate of misperception (estimated based on percentage) suggests that the rate of misperception may increase significantly when either four or more fixed objects, or three or more moving objects, are presented.

著者

Shinsuke TAMURA Tetsuhiro KOREEDA Takashi NAKANO Toshikazu HADA Kazuya HIGASHINO

出版者

The Japanese Society of Internal Medicine

雑誌

Japanese Journal of Medicine (ISSN:00215120)

巻号頁・発行日

vol.29, no.6, pp.611-615, 1990 (Released:2006-03-27)

参考文献数

6

被引用文献数

2 2

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A 53-year-old previously healthy woman suddenly developed adult respiratory distress syndrome (ARDS) of unknown etiology. High-dose corticosteroid pulse therapy and artificial ventilation were started immediately and she dramatically responded to the treatment. However, soon after recovery from ARDS, she developed typical rheumatoid arthritis (RA). Although no apparent relationship between RA and ARDS was clear, this case is quite suggestive in the consideration of the etiology of ARDS.

著者

Yuya Nakano

出版者

Japan Atherosclerosis Society

雑誌

Journal of Atherosclerosis and Thrombosis (ISSN:13403478)

巻号頁・発行日

pp.RV17039, (Released:2019-12-20)

参考文献数

84

被引用文献数

30

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Low birth weight (LBW) infants have higher risk of developing insulin resistance and its comorbidities later in life. The concept of “developmental origins of health and disease” suggests that intrauterine and postnatal environments have an important role in increasing these risks. The risk of such adult-onset diseases in LBW infants might be associated with adipose tissue maldevelopment including altered body composition and increased amount of visceral fat, which is the same mechanism as that in children and adults with metabolic syndrome. However, LBW infants often have different characteristics: they are not always overweight or obese over their life course. The inconsistency might be associated with the thrifty phenotype, which is produced in response to impaired growth potential and decreased lean body mass. LBW infants tend to be obese within the limits of impaired growth potential. Through our previous investigations evaluating longitudinal changes in adiponectin levels at an early stage of life, we speculated that probably, the intrauterine life of term infants or the period up to term-equivalent age in preterm infants might be the key age for the development of adipose tissues including fat cells. Because of that, we hypothesized that the smaller number of adipocytes in LBW infants might be associated with overloading of single adipocytes and impaired adipose tissue expandability. The possible mechanisms are discussed from the perspective of adipose tissue maldevelopment in LBW infants.

著者

Ippei Nakano Shintaro Kinugawa Hiroaki Hori Arata Fukushima Takashi Yokota Shingo Takada Naoya Kakutani Yoshikuni Obata Katsuma Yamanashi Toshihisa Anzai

出版者

International Heart Journal Association

雑誌

International Heart Journal (ISSN:13492365)

巻号頁・発行日

pp.19-400, (Released:2020-01-17)

参考文献数

41

被引用文献数

11

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Heart failure (HF) is associated with aberrant skeletal muscle impairments, which are closely linked to the severity of HF. A low level of brain-derived neurotrophic factor (BDNF), a myokine produced in the skeletal muscle, is known to be involved in reduced exercise capacity and poor prognosis in HF. However, little is known about the factors or conditions of skeletal muscle associated with BDNF levels. We investigated the association between serum BDNF levels and the skeletal muscle mass and function in HF patients (n = 60, 63 ± 13 years) and age-matched controls (n = 29, 61 ± 16 years). The serum BDNF level was significantly lower in the HF patients compared to the controls (24.9 ± 0.9 versus 28.6 ± 1.3, P = 0.021). In a univariate analysis, BDNF was significantly correlated with the peak oxygen uptake, estimated glomerular filtration rate, 10-m gait speed, and muscle strength, but not with the body mass index or lean mass in the HF group. A multiple linear regression analysis revealed that BDNF was independently associated with muscle strength (β-coefficient = 2.80, 95%CI: 1.89-11.8, P = 0.008). Serum BDNF levels were associated with exercise capacity and skeletal muscle function, but not with muscle mass. These novel findings may suggest that BDNF production is controlled by muscle function and activity and consequently regulates exercise capacity, highlighting the importance of adequate training regarding skeletal muscle in HF patients.

著者

Fumio WATANABE Yuri TANIOKA Emi MIYAMOTO Tomoyuki FUJITA Hiroyuki TAKENAKA Yoshihisa NAKANO

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.53, no.2, pp.183-186, 2007 (Released:2008-01-10)

参考文献数

19

被引用文献数

15 19

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Vitamin B12 content (98.8±5.6 μg/100 g dry weight) of an edible cyanobacterium, Nostoc commune (Ishikurage) was determined by the Lactobacillus delbrueckii ATCC 7830 microbiological method. Bioautography with vitamin B12-dependent Escherichia coli 215 indicated that N. commune contained two (main and minor) corrinoid-compounds. These corrinoid-compounds were purified to homogeneity from the dried algal cells and characterized. The main and minor purified corrinoid-compounds were identified as pseudovitamin B12 and vitamin B12, respectively, on the basis of silica gel 60 TLC, C18 reversed-phase HPLC, 1H NMR spectroscopy, and UV-visible spectroscopy. These results suggest that the bacterial cells are not suitable for use as a vitamin B12 source, especially in vegetarians.

著者

一棟 宏子 萩原 美智子 金 貞仁 崔 在順 中野 迪代 若井 希水子 イチムネ ヒロコ ハギワラ ミチコ KIM Jungin CHOI Jeasoon ナカノ ミチヨ ワカイ キミコ Hiroko ICHIMUNE Michiko HAGIWARA Jungin KIM Jeasoon CHOI Michiyo NAKANO WAKAI.Kimiko

雑誌

大阪樟蔭女子大学学芸学部論集

巻号頁・発行日

vol.44, pp.121-136, 2007-03-20

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本研究の目的と方法 韓国ソウル市内の分譲アパート5団地を訪問し、管理方式の実情把握と問題点を考察するために、2005年9月、2006年3月、2006年8月、アパート管理に携わる団地の住宅管理所長(住宅管理士)、住宅代表役員、住宅管理会社社長にインタビュー調査を実施した。結果と考察 韓国では70年代以降、共同住宅が短期間に大量建設された結果、伝統的な住宅様式である戸建住宅数を大幅に上回り、今では住宅ストックの6割以上を占めている。住戸の国民住宅規模は85m~2で日本と比べて広い。供給は分譲アパートが中心で、高層化した大規模団地が多く、多様な住戸規模と平面型が混在している。韓国の管理方式の特徴は、(1)管理に携わる職員の人数が多く、その役割分担は所長、管理事務職、設備系技術職、清掃員、警備員で、警備員の多さが目立つ。(2)建物のメンテナンスは従来20年程度で建替えてきた経緯があり、住民の管理に対する意識は低い。住宅法施工以来、住民の関心は建替えからリモデリングへと移っている。(3)管理を推進する住民の代表役員は立候補や推薦で決められる。全区分所有者による総会開催義務はなく、役員以外は管理に携わる義務もないため役員のなり手不足で、 代表役員の定員に欠員があるまま運営される団地がみられた。(4)韓国の管理方式は、設備中心で日常管理の質は一定程度確保でき、問題解決に機動性が発揮される反面、住民全体の合意形成の手続きが省かれたために、長期計画の展望を持ちにくく、住民自身の管理に対する役割意識が醸成されにくい状況がみられる。

著者

Naoki SUGIMOTO Shu-ichi Nakano

出版者

公益社団法人 日本化学会

雑誌

化学と教育 (ISSN:03862151)

巻号頁・発行日

vol.51, no.7, pp.398-401, 2003-07-20 (Released:2017-07-11)

参考文献数

4

被引用文献数

1

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人から人が産まれたり,子供が親に似るのは,形質が遺伝するためである。この遺伝という現象を化学の視点から捉えられるようになったのは,ここ50年のことである。この遺伝の本質を化学的に理解することは,病気の発症や予防などとの関連で注目を集めており,様々な生物に対して遺伝子の解明が進められている。ここでは,遺伝子の本体であるDNAの化学的な性質について説明し,DNAが遺伝物質である理由とその役割について解説する。

著者

Daisuke MORIOKA Ichiro KITAYAMA Kosuke NAKANO Masato KITANO Takashi YAMANAKA Hideyo KOYAMA Takashi MORIMOTO Hideki SONOBE Noriyuki MIYAZAKI

出版者

The Japanese Society for Experimental Mechanics

雑誌

Advanced Experimental Mechanics (ISSN:21894752)

巻号頁・発行日

vol.1, pp.269-276, 2016-08-31 (Released:2017-02-06)

参考文献数

10

被引用文献数

1

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The purpose of this study was to quantitatively analyze the stress and deformation that occur in plastic ankle-foot orthoses (PAFOs) during walking after it is trimmed. First, PAFOs with incorporated sensors were individually prepared for 2 patients with hemiplegia. Mechanical data were then obtained while individuals wore the PAFOs during walking. Here we report the results of mechanical data and finite element analysis of trimmed plastic ankle-foot orthoses worn by two patients with left-hemiplegia. The results could provide prosthetists with some suggestions for forming orthoses.

著者

Mari Hara Nakano Chihiro Udagawa Arata Shimo Yasuyuki Kojima Reiko Yoshie Hisamitsu Zaha Norie Abe Tokiwa Motonari Mikiko Unesoko Kenji Tamura Tatsunori Shimoi Masayuki Yoshida Teruhiko Yoshida Hiromi Sakamoto Ken Kato Taisei Mushiroda Koichiro Tsugawa Hitoshi Zembutsu

出版者

The Pharmaceutical Society of Japan

雑誌

Biological and Pharmaceutical Bulletin (ISSN:09186158)

巻号頁・発行日

pp.b19-00527, (Released:2019-10-09)

参考文献数

42

被引用文献数

14

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Trastuzumab has been administered to patients with HER2-positive cancer, however, the cardiotoxicity is identified as one of the life-threatening toxicities. Clinically useful biomarker for trastuzumab-induced cardiotoxicity has been expected to be developed. To identify a novel genetic marker(s) determining the risk of trastuzumab-induced cardiotoxicity, we performed a first genome-wide association study (GWAS) in Japanese population. We enrolled 481 patients who had been treated with trastuzumab and carried out a GWAS using 11 cases (with cardiotoxicity) and 257 controls (without cardiotoxicity). Top 100 single nucleotide polymorphisms (SNPs) which revealed the smallest P values in GWAS (P = 7.60 x 10-7 - 2.01 x 10-4) were further examined using replication samples consisted of 14 cases and 199 controls. The combined analysis of the GWAS and replication study indicated possible association of five loci with trastuzumab-induced cardiotoxicity (rs9316695 on chromosome 13q14.3, rs28415722 on chromosome 15q26.3, rs7406710 on chromosome 17q25.3, rs11932853 on chromosome 4q25, and rs8032978 on chromosome 15q26.3, Pcombined = 6.00 x 10-6, 8.88 x 10-5, 1.07 x 10-4, 1.42 x 10-4, 1.60 x 10-4, respectively). Furthermore, we developed a risk prediction model for trastuzumab-induced cardiotoxicity using the five marker SNPs. The incidence of trastuzumab-induced cardiotoxicity in patients with risk score ≥ 5 was significantly higher (42.5%) compared to that in patients with score ≤ 4 (1.8%) (P = 7.82 x 10-15, odds ratio = 40.0). These findings suggest the potential to improve the ability of physicians to avoid the trastuzumab-induced cardiotoxicity for patients with HER2-positive cancer.

著者

中野 毅 Tsuyoshi NAKANO

出版者

創価大学社会学会

雑誌

SOCIOLOGICA (ISSN:03859754)

巻号頁・発行日

vol.30, no.2, pp.19-43, 2006-03-01

著者

Yasuo Terasawa Hiroyuki Tashiro Yukari Nakano Takashi Tokuda Jun Ohta

出版者

Japanese Society for Medical and Biological Engineering

雑誌

Advanced Biomedical Engineering (ISSN:21875219)

巻号頁・発行日

vol.5, pp.137-141, 2016 (Released:2017-01-12)

参考文献数

19

被引用文献数

2 5

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Implantable neural stimulators have recently attracted attention because of their potential applicability to the treatment of sensory neural disorders such as hereditary hearing loss and retinitis pigmentosa. However, the requirements for stimulation electrodes tend to be contradictory in some applications that require transmission of complex information to the nervous system, such as cochlear implants and retinal prostheses. They have to be sufficiently small to realize fine interfacing with the nervous system while remaining sufficiently large to inject enough charge to stimulate neurons without causing an irreversible electrochemical reaction. One solution to these requirements is to employ three-dimensional (3D) instead of planar electrodes. However, in conventional photolithography, the available material and size for fabricating electrodes are greatly limited. To overcome these limitations, we propose a novel fabrication process for stimulation electrodes, using mechanical micromachining. Using 3D bullet-shaped electrode increased the surface area by 3.6 times compared to conventional planar electrode with the same diameter. The proposed electrode, which was developed for retinal prostheses, showed sufficient charge injection capacity (CIC) to evoke light perception (phosphene) for blind patients. Furthermore, the CIC and electrode surface morphology remained stable during a six-month period of current pulsing in phosphate-buffered saline, which suggests suitability for chronic neural stimulation. The cause of the variance in the measured CIC and future applications of the proposed 3D electrodes were also considered.

著者

中野 泰 Nakano Yasushi

出版者

神奈川大学 国際常民文化研究機構

雑誌

神奈川大学 国際常民文化研究機構 年報 (ISSN:21853339)

巻号頁・発行日

vol.1, pp.57-74, 2010-10-30

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本稿は、「漁業民俗」の研究動向(1980年代〜)を取り上げ、海洋民族学(海洋人類学)と対比しつつ、社会・歴史的文脈を重視する視角から整理・検討した。研究史の展開を4つのテーマ領域(「漁民社会研究」「知識・技能研究」「サブシステンス研究」「資源利用の研究」)別に整理し、以下の3 点が主たる課題として導かれた。 既存の「漁業民俗」の研究においては、第一に、「漁業民俗」の担い手の位置づけが、漁村、あるいは主体的個人という二通りの捉え方に乖離したままで不充分であること、第二に、「漁業」の範囲を、生産や技能中心の概念へ暗黙裡に限定しており、現況を捉える困難さがあること、第三に、変化の契機、条件や要因の分析が不充分な点である。 以上の課題に対し、本稿では、第一に、世帯・家族レベルに焦点化して「主体」概念を深化させ、社会構造との間の弁証法的関係を重層的に関連づける必要を説いた。そのためには、具体的な場の文脈に即して検討する必要がある。第二に、「漁業」概念を拡張し、家内労働を含め、地域社会における生活文化と連関させること、第三に、地域社会外と連鎖する関係性も捉え、科学技術や社会経済の動向などのより広い国内外の時代的文脈に位置付け、変動の契機、その諸条件や要因の分析が必要であると説いた。 漁業をめぐる価値観が多様化しつつある現在、「漁業民俗」の研究は、グローバルに展開する関係性を対象に入れ、異なる立場で関わる者へもミクロに迫り、現象を取り巻く力関係を歴史的社会的文化的文脈へ位置づける必要がある。その力関係を対象化する上で、巷間に流布する「海民」概念など、「主体」に関わる民俗学の表象が有する歴史的背景と政治性への省察を行う必要もあることを説いた。

著者

中野 敬一 Keiichi NAKANO

雑誌

神戸女学院大学論集 = KOBE COLLEGE STUDIES

巻号頁・発行日

vol.59, no.2, pp.103-120, 2012-12-20

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Chiristianity was first introduced into Japan in 1549 by the Catholic missionary, Francis Xavier. However, Christians were persecuted quite strongly by the ruling forces of the time. By the mid 17th centuty, missionary work conducted in public had completely ceased to exist. Christianity was re-introduced into Japan in 1859. In the Meiji era various sects of Protestant and Catholic missionary groups from various contries, particularly from the United States, arrived in Japan once again and started their missionaty work. Missionaty groups introduced Japanese to Christian ideas of the other world (afterworld, the world beyond) and Japanese who became Christian believed what the missonaries taught. What kinds of ideas have Japanese accepted and developed? To know the ideas of the other world of Japanese converts in the Meiji era, we study sermons and articles by famous Japanese preachers (such as Jo Niijima, Masahisa Uemura, Kanzo Uchimura and so on), tracts written by missionaries, and hymns that Christians in Japan used in the Meiji era. Studying these materials, we could see some common characteristics of the ideas of the other world. The preachers or missinaries insist that there is a "Heaven" with God. In heaven, the deceased have peace and happiness, and can meet Got and the other dead who already were there. In particular, "to meet again" with family members or friends are significant words for hope in Heaven. The Japanese Christians who believed these ideas must have been comforted and given hope for their future. The important thing that we have to comfirm is that we could not see any specific image of Heaven or Hell. For example, they ded not talk about the form or shape of Heaven, or the condeition of the deceased.

著者

中野 研一郎 Kenichiro Nakano

出版者

関西外国語大学

雑誌

人権を考える = Thinking about human rights : 関西外国語大学人権教育思想研究所紀要 (ISSN:2189177X)

巻号頁・発行日

no.22, pp.153-162, 2019-03

著者

中野 達哉 Nakano Tatsuya

出版者

駒沢史学会

雑誌

駒沢史学 (ISSN:04506928)

巻号頁・発行日

no.79, pp.27-57, 2012-11

著者

Nakano Takashi Fukuyama Hidetoshi

出版者

一般社団法人日本物理学会

雑誌

Journal of the Physical Society of Japan (ISSN:00319015)

巻号頁・発行日

vol.50, no.8, pp.2489-2499, 1981-08-15

被引用文献数

1 111

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Our previous calculations of the lattice distortion and the formation energy ofa soliton in the one-dimensional antiferromagnetic Heisenberg spin-Peierlssystems are refined and extended to the case of X Y-Z model. The spin degree offreedom are represented by the phase Hamiltonian with the help of boson repre-sentation of fermions introduced by the Jordan-Wigner transformation. Parame-ters in this phase Hamiltonian are adjusted so that spin wave velocity and exponentof correlation function agree with exact results. This adjustment is shown togive also exact spin susceptibility in the absence of lattice distortion. Based onthis phase Hamiltonian of the X Y-Z model localized excitations (solitons) inthe presence of lattice distortions are examined in details including the width,the formation energy and the magnetic field dependence.

著者

Koji Nakano Toru Ohara

出版者

Global Business Research Center

雑誌

Annals of Business Administrative Science (ISSN:13474464)

巻号頁・発行日

vol.18, no.2, pp.75-84, 2019-04-15 (Released:2019-04-15)

参考文献数

8

被引用文献数

2

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Japan has since ancient times had a custom called omiai (loosely translated as “matchmaking” when searching for a marriage partner). The examples of the matching of large firms and start-ups at the Innovation Leaders Summit in Japan discussed in this paper can truly be called “omiai.” Unlike Western-style matching, in this summit, participating firms and managers alike have little experience with alliances, and matchmakers have no strong commitment, as noted by Holzmann, Sailer, and Katzy (2014). Instead, just as with omiai, matchmakers exchange profiles of large firms and start-ups new to alliances and simply create a place for them to meet and make matches.

著者

タグチ ミナ イワサ レイコ サイトウ ヨシヤ ナカノ テルミ Mina Taguchi Reiko Iwasa Yoshiya Saito Terumi Nakano

雑誌

国際基督教大学学報. I-A, 教育研究 = Educational Studies

巻号頁・発行日

vol.33, pp.127-143, 1991-03

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This study was a trial for developing a multi-media learning package which combines a broadcasting program with other media. NHK School Broadcasting Special Series, "Hearing a Story -Totto-chan-", was chosen for the study, and a learning system incorporating it was constructed. A personal computer connected to simulated CD-ROM was selected as the medium for making maximum use of the strengths and for compensating for the weaknesses of the TV program, which is to improve students' listening ability. A CAI system for producing optimal learning was developed, and its effects were validated.

著者

CHIBUEZE James O. IMURA Kenji OMODAKA Toshihiro HANDA Toshihiro NAGAYAMA Takumi FUJISAWA Kenta SUNADA Kazuyoshi NAKANO Makoto KAMEZAKI Tatsuya YAMAGUCHI Yoshiyuki SEKIDO Mamoru

出版者

IOP Publishing

雑誌

The Astrophysical Journal (ISSN:0004637X)

巻号頁・発行日

vol.762, no.1,

被引用文献数

7

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We mapped the (1,1), (2,2), and (3,3) lines of NH3 toward the molecular cloud associated with the Monkey Head Nebula (MHN) with a 1.'6 angular resolution using a Kashima 34 m telescope operated by the National Institute of Information and Communications Technology (NICT). The kinetic temperature of the molecular gas is 15-30 K in the eastern part and 30-50 K in the western part. The warmer gas is confined to a small region close to the compact H II region S252A. The cooler gas is extended over the cloud even near the extended H II region, the MHN. We made radio continuum observations at 8.4 GHz using the Yamaguchi 32 m radio telescope. The resultant map shows no significant extension from the Hα image. This means that the molecular cloud is less affected by the MHN, suggesting that the molecular cloud did not form by the expanding shock of the MHN. Although the spatial distribution of the Wide-field Infrared Survey Explorer and Two Micron All Sky Survey point sources suggests that triggered low- and intermediate-mass star formation took place locally around S252A, but the exciting star associated with it should be formed spontaneously in the molecular cloud.

著者

YOSHINORI YAMASHITA YUTAKA SAITOH KATSUHIKO ANDO KEIICHI TAKAHASHI HIROE OHNO HIROFUMI NAKANO

出版者

JAPAN ANTIBIOTICS RESEARCH ASSOCIATION

雑誌

The Journal of Antibiotics (ISSN:00218820)

巻号頁・発行日

vol.43, no.10, pp.1344-1346, 1990-10-25 (Released:2006-04-19)

参考文献数

6

被引用文献数

14 33