著者

及川 尚

出版者

The Oto-Rhino-Laryngological Society of Japan, Inc.

雑誌

日本耳鼻咽喉科学会会報 (ISSN:00306622)

巻号頁・発行日

vol.93, no.3, pp.361-372, 1990-03-20 (Released:2008-03-19)

参考文献数

16

被引用文献数

1

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I. ObjectiveThe present study was undertaken in order to determine the onset of monaural deafness, especially whether it is congenital or acquired, making an investigation into the sense of sound direction in monaural hearing impairment and monaural deafness and compairing them between hearing-impaired patients and normal hearers.II. SubjectsThis study was carried out on 26 patients with monaural hearing impairment, 22 patients with monaural deafness and 10 normal hearers.III. MethodsA circle with a radius of 1.3m was drawn around a fixed patient's position in a sound proof room, and the circle was divided into 16 directions at an equal angle of 22.5°. A blindfolded hearer was instructed to listen to a speaker for white noise of 60dB (A) for one second and verbally answer in which direction he heard the noise. The normal hearers were tested in 4-, 8-, and 16-directions, and the hearing-impaired patients were tested in only 8-directions.IV. Results1. Normal HearersThe rate of correct answers decreased with increasing directions of sound.The incorrect answers in 4-direction testing were only confusion between forward and backward directions, and similar incorrect answers were made in 8- and 16-direction testing. All other incorrect answers were errors of less than 45°.2. Monaurally Hearing-impaired PatientsThe rate of correct answers on the whole was low.There was such a relationship between the rate of correct answers and the mean hearing level of patients that the total rate of correct answers decreased with increasing hearing impairment. This correlation was statistically significant, and there was a still more significant correlation between the degree of hearing impairment and the rate of correct answers as to the right and left directions.Incorrect answers were errors of90° or less on the healthy side, while errors were made for all directions on the affected side.3. Monaurally Deaf PatientsThe rate of correct answers was by far lower on the affected side.Whereas many errors were within 45° on the healthy side, errors were made for all directions on the affected side.Judging from the onset of hearing loss, the monaurally deaf patients were divided into a group of 8 patients who obviously had sudden aquired deafness and a group of 9 patients who were presumed to have congenital monaural deafness. The mean rate of correct answers of the former group was superior to the latter group's, particularly on the effected side.

著者

寺尾 彬 佐藤 靖雄

出版者

The Oto-Rhino-Laryngological Society of Japan, Inc.

雑誌

日本耳鼻咽喉科学会会報 (ISSN:00306622)

巻号頁・発行日

vol.81, no.2, pp.101-105, 1978-02-20 (Released:2008-03-19)

参考文献数

12

被引用文献数

1

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Thirty-five patients with cedar pollinosis were studied for clarifying the specificities of HLA antigens. Identification of HLA types was based on the result of the lymphocyte microcytotoxity test. There was a significantly high incidence of HLA-A10 and HLA-BW15 in cedar pollinosis.The incidence of HLA-A10 was 11.7% in the control group and 68.6% (X2=49. 1, p<10-6, Pc <10-5) in the patients, while that of HLA-BW 15 was 37. 1 % (X2= 12.8, p=5×10-', Pc=8 × 10-3) in the patients compared to 11.7% in the control.

著者

樫尾 明憲 中尾 一成 持木 将人 二藤 隆春 菅澤 正

出版者

The Oto-Rhino-Laryngological Society of Japan, Inc.

雑誌

日本耳鼻咽喉科学会会報 (ISSN:00306622)

巻号頁・発行日

vol.107, no.12, pp.1053-1059, 2004-12-20 (Released:2008-12-15)

参考文献数

39

被引用文献数

6 8

著者

癖瀬 肇 桐谷 滋 吉岡 博英 沢島 政行 牛島 達次郎

出版者

The Oto-Rhino-Laryngological Society of Japan, Inc.

雑誌

日本耳鼻咽喉科学会会報 (ISSN:00306622)

巻号頁・発行日

vol.80, no.12, pp.1475-1482, 1977-12-20 (Released:2008-03-19)

参考文献数

22

被引用文献数

1

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By means of pellet tracking technique using an x-ray microbeam system, observations of articulatory movements were made on clinical cases of cerebellar degeneration. In some selected cases, electromyographic study was also performed. The data were specifically examined with reference to the range, velocity and consistency (reproducibility) of the movements of the articulators as well as to the pattern of coordination of the different articulators involved. It was found in the case of ataxic dysarthria of cerebellar origin, that the dynamic patterns were best repesented by difficulty in initiation of purposive movements and inconsistency of artieulatory movements, particularly in repetitive production of monosyllable. On electromyography, breakdown of the rhythmical patterns in the articulatory muscles was quite obvious in the repetition of monosyllables. It was suggested that analysis of dynamic aspects of the dysarthrias shoulc he a promising approach for elucidating the nature of central problems of speech productior and for differential diagnosis of various types of dysarthrias.

著者

打越 進 野村 公寿 木村 廣行 宇佐 神篤

出版者

The Oto-Rhino-Laryngological Society of Japan, Inc.

雑誌

日本耳鼻咽喉科学会会報 (ISSN:00306622)

巻号頁・発行日

vol.84, no.4, pp.374-378, 1981-04-20 (Released:2008-03-19)

参考文献数

12

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Six patients with nasal allergy due to Japanese Apricot pollen which are called "Ume" pollen were clinically examined. All cases had hyperrhinorrhea and nasal obstruction with ocular symptoms, and one of them also had itching in the pharynx. They have lived for 8 to 47 years near by a large grove of Japanese apricot and 4 of them were fruit-growers. Among these four cases, three have suffured from nasal and ocular symtoms while they were working in the grove. These cases had positive skin reaction to clude "Ume" pollen extract, and five patients also reacted to nasal and ocular provocative tests.Serum IgE value by RIST was distributed from 98 to 2300IU/ml (mean value 887IU/ml). Specific anti-"Ume" pollen IgE in the serum was measured by BrCN activated RAST method, and serum value of five patients was 1.6 timed to 3.5 times higher than that of non-allergic subjects.Air-borne "Ume" pollen collected in a grove were observed from the beginning of February to the middle of March, and maximum grain count was 43 per cm2 in 24 hours.

著者

吉田 雅文 相良 哲哉 長野 美貴 是永 克実 牧嶋 和見

出版者

The Oto-Rhino-Laryngological Society of Japan, Inc.

雑誌

日本耳鼻咽喉科学会会報 (ISSN:00306622)

巻号頁・発行日

vol.95, no.2, pp.195-200, 1992-02-20 (Released:2008-03-19)

参考文献数

7

被引用文献数

1

---

The discrimination of mono-syllable words (67S word-list) pronounced by a male and a female speaker was investigated in noise in 39 normal hearing subjects. The subjects listened to the test words at a constant level of 62 dB together with white or weighted noise in four S/N conditions. By processing the data with logit transformation, S/N-discrimination curves were presumed for each combination of a speech material and a noise. Regardless of the type of noise, the discrimination scores for the female voice started to decrease gradually at a S/N ratio of +10dB, and reached 10 to 20% at-10dB. For the male voice in white noise, the discrimination curve was similar to those for the female voice. On the contrary, the discrimination score for the male voice in weighted noise declined rapidly from a S/N ratio of +5dB, and went below 10% at -5dB. The discrimination curves seem to be shaped by the interrelations between the spectrum of the speech material and that of the noise.

著者

杉内 友理子

出版者

The Oto-Rhino-Laryngological Society of Japan, Inc.

雑誌

日本耳鼻咽喉科学会会報 (ISSN:00306622)

巻号頁・発行日

vol.91, no.11, pp.1910-1919, 1988-11-20 (Released:2008-03-19)

参考文献数

30

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The spinal location of individual motor nuclei of the thoracic dorsal paravertebral muscles was investigated in the cat, using retrograde labelling of motoneurons with horseradish peroxidase (HRP). HRP was injected into the peripheral nerves innervating Mm. rotatores, M. multifidus, M. spinalis dorsi, M. longissimus dorsi and M. iliocostalis. The retrogradely-labelled motoneurons of a particular muscle were arranged in a longitudinal column-like fashion for the length of one segment in a localized area of the spinal ventral horn (the ventromedial or the lateromedial nuclei in lamina IX of Rexed). To compare the relative locations of the motor nuclei of different muscles in the ventral horn, two different muscle nerves (one for each side) were injected with HRP bilaterally at the same segmental level. The motor nuclei of Mm. rotatores, M. multifidus, M. spinalis dorsi, M. longissimus dorsi and M. iliocostalis were arranged in this order from the medial to the lateral portion of the ventral horn. This mediolateral order of arrangement of the motor nuclei was discussed in relation to the classification of the dorsal paravertebral muscles based on the comparative anatomical study.

著者

戸田 行雄 中島 久美 漆畑 保 甲斐 園子 五島 久子 堤康 一朗 竹山 勇

出版者

The Oto-Rhino-Laryngological Society of Japan, Inc.

雑誌

日本耳鼻咽喉科学会会報 (ISSN:00306622)

巻号頁・発行日

vol.88, no.7, pp.896-905, 1985-07-20 (Released:2008-03-19)

参考文献数

16

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Twenty normal hearing young adults ingested 1.4ml alcohol per kg body weight over 60 minutes. Then the blood alcohol levels, breath alcohol levels were measured by Dupont ACA blood analyzer and DPA-2 breath analyzer. Also the thresholds and the amplitudes of the acoustic reflex were measured by impedance audiometer ZO-72, using 1.5sec., 500Hz., pure tone stimulation contralaterally in 13 persons, and ipsilaterally in 7 persons. First, the thresholds were decided and then the amplitudes were recorded after the stimulation by the sounds of 20dB more than those of before drinking alcohol. The results were as follows: 1) In 13 persons who the stimulation were given contralaterally, the amplitudes were decreased at the point of just finishing drinking. Four persons showed remarkable decrease, while five showed no significant change. 2) In 7 persons, who the stimulation were given ipsilaterally, the thresholds were increased at the points of just finishing drinking, 30 minutes later, 60 minutes later. No variability was found among them. 3) No significant relations were found not only between the blood alcohol levels and the changes of the thresholds, but also between the blood alcohol levels and the changes of the amplitudes. From the above mentioned, it was concluded that the acoustic reflex was depressed when people drink alcohol, and people will get morepossibilities of suffering from acute sensorineural healing loss if they are exposed to loud sounds while drinking, like in discos.

著者

福島 龍彦

出版者

The Oto-Rhino-Laryngological Society of Japan, Inc.

雑誌

日本耳鼻咽喉科学会会報 (ISSN:00306622)

巻号頁・発行日

vol.60, no.8, pp.1052-1084, 1957-08-20 (Released:2008-03-19)

参考文献数

50

被引用文献数

1

著者

調所 廣之 福島 淑子 小柳津 聖子 岡 嗣郎 黒石 敏弘 風間 玲子 藤居 荘二郎 浅賀 英世

出版者

The Oto-Rhino-Laryngological Society of Japan, Inc.

雑誌

日本耳鼻咽喉科学会会報 (ISSN:00306622)

巻号頁・発行日

vol.83, no.5, pp.519-523, 1980-05-20 (Released:2008-03-19)

参考文献数

7

被引用文献数

3 2

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A standard olfactory acuity test using T & T olfactometer has recently been developed and gradually becomes in wide use, while the conventional intravenous olfaction test is also widely used.In the present experiment we studied the relationship between results of these olfactory tests and prognosis in 180 patients with olfactory disturbances who had received the nose-drop treatment with glucocortico steroid hormone. As a result, cure or improvement was attained in 88 percent of the patients who gave a positive reaction to the standard olfactory acuity test and in 66 percent of those who were judged to be scaleout in this test.In the case of the intravenous olfaction test, cure or improvement was attained in 90 percent of cases which gave a positive reaction and in 40 percent of the negative cases. Particularly in reference to the patients who gave a negative reaction to the intravenous olfaction test, one out of 65 cases attained cure and 39 cases remained unchanged. The intravenous olfaction test proved most effective among the tests to tell the prognosis of olfactory disturbances.

著者

大迫 廣人 春田 厚 坪井 陽子 松浦 宏司 小宗 静男

出版者

The Oto-Rhino-Laryngological Society of Japan, Inc.

雑誌

日本耳鼻咽喉科学会会報 (ISSN:00306622)

巻号頁・発行日

vol.104, no.5, pp.514-517, 2001-05-20 (Released:2010-10-22)

参考文献数

14

被引用文献数

2 4

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耳かきによる機械的刺激が外耳道湿疹の原因となり, その繰り返す慢性炎症が癌誘発の一因と考えられた外耳道癌症例を経験した. 外耳道肉芽腫を伴う外耳道湿疹が軽快せず平成9年7月生検を行った結果, 左外耳道癌と診断された. 外科的治療および化学療法, 放射線治療を行うも効を奏せず腫瘍が拡大進展し, 約8ヵ月後には対側の右外耳道に癌が発症した. 最終的に不幸な転帰をとったが, 両耳の病巣についてDNA遺伝子解析を行いその結果P53遺伝子の異常により両外耳道癌は転移性癌ではなく全く独立した重複癌ということが判明した.

著者

羽柴 基之 安井 桂子 渡部 啓孝 松岡 徹 馬場 駿吉

出版者

The Oto-Rhino-Laryngological Society of Japan, Inc.

雑誌

日本耳鼻咽喉科学会会報 (ISSN:00306622)

巻号頁・発行日

vol.98, no.4, pp.681-696,759, 1995-04-20 (Released:2010-10-22)

参考文献数

80

被引用文献数

1

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我々は, パソコンを使用してEOGで記録した水平追従眼球運動を自動的に定量評価する方法を開発した. 方法の骨子は, 視標追跡運動が滑動性追従眼球運動 (SPEM) と衝動性眼球運動 (saccade) という全く異なった2種類の眼球運動から成り立ってる事実に基づく. 眼球運動波形からsaccadeの生理学的条件に基づいて作成したアルゴリズムにより, saccade成分を抽出し, 取り除き, SPEM成分のみで再構築した眼球運動波形を周波数分析法により処理した. この方法により, SPEM成分のみの利得と位相の評価が可能になった.

著者

大山 勝 三吉 康郎 荘司 邦夫 山本 真平 谷口 知恵子 渡辺 真吾 井 研治

出版者

The Oto-Rhino-Laryngological Society of Japan, Inc.

雑誌

日本耳鼻咽喉科学会会報 (ISSN:00306622)

巻号頁・発行日

vol.79, no.9, pp.963-972, 1976-09-20 (Released:2008-03-19)

参考文献数

9

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The bone-conducted vowels were picked up by the vibration transducer of the accelerationtype applying to three anatomical sites on the heads (forehead, upper jaw and mastoid region)of the healthy adults.A comparative studies on the speech signals from these three regions of the head were done acoustically. The results were summarized as follows; i) for the pickup of speech signals from the body surface, the vibration transducer of small acceleration type (Rion Co. PV-06)was the most satisfactory in point of a signal-to-noise ratio, intelligibility of the speech and practical use. 2) the relative intensities of the speech signals were decreased in regular order i, u, e, o and a. 3) the spectral characteristics of these vowels were highly similar to those which were recorded from the micropone at the position in the distance of 30 cm from the lips, although there was an inclination of the increased low-frequency components with the decrease of high-frequency in the spectrum. 4) from the results of the articulation score, intelligibility of the vowels was much better in recorded sounds from the upper jaw and forehead compared with that from the mastoid region.

著者

池田 卓生 関谷 透 木戸 利成 金谷 浩一郎 田原 哲也 原 浩貴

出版者

The Oto-Rhino-Laryngological Society of Japan, Inc.

雑誌

日本耳鼻咽喉科学会会報 (ISSN:00306622)

巻号頁・発行日

vol.97, no.4, pp.703-708, 1994 (Released:2008-03-19)

参考文献数

7

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今回我々は,北海道上砂川町にある地下無重力実験センター(Japan Microgravity Center: JAMIC)を利用する機会を得たので,これが身体平衡系の研究における新しい実験手段として有用であるかを検討する目的で,平衡系実験セット(姿勢•行動観察用及び筋電図記録用)を作製し,カエルを用いた予備実験を行った.1) 姿勢•行動観察では,無処置群において頭部が背屈し,四肢が伸展するという特徴的な姿勢が観察できた.また前庭神経切断群では,落下前の姿勢変化はそのまま持続し,障害側を下にする回転運動が見られた.2) 筋電図では,落下直後に前庭脊髄反射のためと考えられる筋活動の亢進を認めた.また前庭神経切断例では,術側の潜時が,やや遅延した.3) カエルは,落下実験施設を利用した平衡系実験の実験動物として適当である.4) 微小重力暴露時の身体平衡系の研究において,落下実験施設は非常に有用な実験手段である.

著者

牧山 清

出版者

The Oto-Rhino-Laryngological Society of Japan, Inc.

雑誌

日本耳鼻咽喉科学会会報 (ISSN:00306622)

巻号頁・発行日

vol.89, no.4, pp.425-432, 1986-04-20 (Released:2008-03-19)

参考文献数

35

被引用文献数

1 1

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It is well known that histamine is the most important chemical mediator of nasal allergy, and histamine hypersensitivity of the nasal mucosa has been also recognized in the patients with nasal allergy. Therefore, the degradation or inactivation of histamine released from basophilic cells following reaginic antigen-antibody reaction is very important in the patients from a view point of the defence mechanism of the body. The purpose of this study is to investigate the levels of plasma histaminase of allergic patients both in pollen season and in season without pollen of Japanese cedar. The patients have developed clear symptoms due to allergen challenge during the pollen season. Higher plasma histaminase activity was revealed in pollen season than that out of season. Furthermore, close relations were recognized among the plasma histaminase activity and nasal symptoms, local findings, eosinophils in nasal secretion, and histamine sensitivity of nasal mucosa during the pollen season.

著者

西池 季隆 坂田 義治 加藤 崇 長井 美樹 小西 雅樹

出版者

The Oto-Rhino-Laryngological Society of Japan, Inc.

雑誌

日本耳鼻咽喉科学会会報 (ISSN:00306622)

巻号頁・発行日

vol.105, no.10, pp.1065-1070, 2002-10-20 (Released:2008-03-19)

参考文献数

20

被引用文献数

2 4

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平成6年から平成14年の間に市立吹田市民病院において治療した下顎骨骨折35例を検討した.男女比は2:1であった.年齢別では20歳代が最も多く全体の31%を占めた.受傷原因では,交通事故52%,殴打31%,転倒•転落17%であった.骨折部位の頻度は,関節突起33%,おとがい部25%,角部22%,体部10%,枝部10%であった.30歳未満では受傷原因として交通事故および殴打が有意に多く,30歳以上で転倒•転落が多かった.交通事故や転倒•転落では関節突起骨折が有意に多く,殴打では他の部位の骨折が多かった.治療は,チタンあるいは吸収性プレートによる観血的治療および顎間固定30例,顎間固定のみ2例,保存治療1例,他院での治療2例であった.顎間固定の期間は平均42日であった.6ヵ月以上経過を追えた22例中後遺症は6例であった.痛み4例,咬合不全1例,顎関節雑音1例,顔面神経側頭枝の麻痺1例であった.関節突起骨折では他の部位の骨折に比較して有意に後遺症が多く発生していた.今後の当院における下顎骨骨折治療の検討課題は,顎間固定期間の短縮化,吸収性プレートの適用の拡大,関節突起骨折の治療方法の検討であると考えられた.

著者

冨山 道夫

出版者

The Oto-Rhino-Laryngological Society of Japan, Inc.

雑誌

日本耳鼻咽喉科学会会報 (ISSN:00306622)

巻号頁・発行日

vol.96, no.7, pp.1133-1140,1225, 1993-07-20 (Released:2010-10-22)

参考文献数

24

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鼓膜切開を要した小児急性中耳炎症例81名にcefaclor (CCL) とfosfomycin (FOM) 点耳液を併用し有用性を検討した. その後1年間の経過観察を行い, 検査所見と治療経過, 予後との関連を調査し以下に示す結果を得た. 1) CCLとFOM点耳液の有効率は99%であった. 2) レントゲン検査で乳突蜂巣陰影 (蜂巣陰影), 副鼻腔陰影のある群は有意に経過が遷延した. 3) 蜂巣陰影のある群は難治な滲出性中耳炎に移行しやすく, 蜂巣陰影のある群と急性中耳炎の既往がある群では有意に急性中耳炎の再発を認めた. 4) 両側蜂巣に陰影がある群と陰影が片側例のうち対側耳に比べ患側耳の蜂巣発育が抑制されている群は, 再発や難治な滲出性中耳炎への移行を示しやすい傾向がみられた.

著者

村井 紀彦 谷口 善知 高橋 由佳 安原 裕美子 窪島 史子 楯谷 一郎

出版者

The Oto-Rhino-Laryngological Society of Japan, Inc.

雑誌

日本耳鼻咽喉科學會會報 (ISSN:00306622)

巻号頁・発行日

vol.114, no.7, pp.615-619, 2011-07-20

参考文献数

16

被引用文献数

6

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目的: 2004年に日本臨床細胞学会において提唱された, 唾液腺細胞診に関する新報告様式の当科での運用状況, 有用性と問題点を検討すること. 対象と方法: 2006年から2010年までの4年間に, 術前穿刺吸引細胞診と外科的切除を行った44例を対象とし, カルテをレトロスペクティブに調査し, 細胞診の結果, 病理組織診断等を記録した. 結果: 耳下腺原発が33例, 顎下腺原発は11例, 悪性は8例, 良性は36例であった. 良性例のうちの2例は検体不適正であり, また, 良性例のうちの4例と悪性例のうちの1例は「鑑別困難」と判定された. 真陽性は3例, 真陰性は30例で, 偽陰性が4例あり, 偽陽性例はなかった. 感度, 特異度, 正診率はそれぞれ42.9% (4/7), 100% (30/30), 89.2% (34/37) であった. 精度管理指標については, 検体不適正率は4.5% (2/44), 良悪性鑑別困難率は11.4% (5/44), 悪性疑い例の悪性率は100% (2/2) であった. 結論: 新報告様式の使用により, パパニコロウ分類の報告結果に対する臨床医の解釈の曖昧さが減少し, 臨床的に有意義であると考えられた.

著者

中屋 宗雄 森田 一郎 奥野 秀次 武田 広誠 堀内 正敏

出版者

The Oto-Rhino-Laryngological Society of Japan, Inc.

雑誌

日本耳鼻咽喉科學會會報 (ISSN:00306622)

巻号頁・発行日

vol.105, no.1, pp.22-28, 2002-01-20

参考文献数

30

被引用文献数

1 2

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目的: ライフル射撃音による急性音響性難聴の聴力像と治療効果に対する臨床的検討を行った.<BR>対象と方法: ライフル射撃音による急性音響性難聴と診断され入院加療を行った53例, 74耳とした. 治療方法別 (ステロイド大量漸減療法群23耳とステロイド大量漸減療法+PGE<SUB>1</SUB>群51耳) と受傷から治療開始までの期間別 (受傷から治療開始まで7日以内の群42耳と8日以降の群32耳) に対する治療効果と聴力改善 (dB) についてretrospectiveに検討した. また, 各周波数別に治療前後の聴力改善 (dB) を比較検討した.<BR>結果: 全症例の治癒率19%, 回復率66%であった. ステロイド大量漸減療法群では治癒率17%, 回復率78%, ステロイド大量漸減療法+PGE<SUB>1</SUB>群では治癒率24%, 回復率63%であり, 両者の群で治療効果に有意差を認めなかった. 受傷から7日以内に治療を開始した群では治癒率21%, 回復率78%, 受傷から8日目以降に治療を開始した群では治癒率16%, 回復率50%であり, 受傷から7日以内に治療を開始した群の方が有意に治療効果は高かった. 入院時の聴力像はさまざまな型を示したが, 2kHz以上の周波数において聴力障害を認める高音障害群が50耳と多く, 中でも高音急墜型が20耳と最も多かった. また, 治療前後における各周波数別の聴力改善 (dB) において, 500Hz, 1kHzの聴力改善 (dB) は8kHzの聴力改善 (dB) よりも有意に大きかった.<BR>結論: 今回の検討で, 受傷後早期に治療を行った症例の治療効果が高かったことが示された. また, 高音部より中音部での聴力障害は回復しやすいと考えられた.

著者

立川 拓也 熊澤 博文 京本 良一 湯川 尚哉 山下 敏夫 西川 光重

出版者

The Oto-Rhino-Laryngological Society of Japan, Inc.

雑誌

日本耳鼻咽喉科学会会報 (ISSN:00306622)

巻号頁・発行日

vol.104, no.2, pp.157-164, 2001-02-20 (Released:2010-10-22)

参考文献数

21

被引用文献数

4 8

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1984年から1998年の15年間に関西医科大学耳鼻咽喉科において手術を施行した甲状腺分化癌を対象に統計学的観察と予後因子の検討を行った.対象症例は乳頭癌177症例, 瀘胞癌50症例, 男性45名, 女性182名, 年齢は13歳から89歳であった.年度別症例数から甲状腺腫瘍症例の増加, 特に乳頭癌の増加が確認された. 一方瀘胞癌の症例数の増加傾向は見られなかった.年齢分布として乳頭癌は40代から60代にpeakを認め, 瀘胞癌は50代にpeakが認められた.原発巣切除に関して, 乳頭癌はT因子が大きくなるにつれ, より広い原発巣切除が行われていたが, 瀘胞癌は術前, 術中に確定診断がつきにくいためか, 峡葉切除術が大部分 (70%) を占めていた.リンパ節郭清に関して, 乳頭癌症例はTが大きくなるに従い, より広い範囲の郭清術が施行されていた. 一方瀘胞癌症例は原発巣切除と同様確定診断がつきにくいためか, リンパ節郭清は70%がD1領域郭清であった.局所再発が22症例, 遠隔転移が6例に認められた. 局所再発22症例中手術で14例がsalvageできた.死亡症例は17症例に認められ, 乳頭癌12症例 (原病死は11症例), 瀘胞癌5症例 (原病死は2症例) であった. 原病死13症例の中でT4症例が10例, T3症例が3例, Nla症例が3例, Nlb症例が8例を占めていた. 死亡症例に関してはやはり進行症例が多かった.予後因子としてT, N, M, 年齢, 性別を対象として検討した. 乳頭癌の予後因子は被膜外浸潤, 遠隔転移, 年齢であり, 瀘胞癌の予後因子は遠隔転移であった.乳頭癌の5年生存率は93.0%, 10年生存率は88.8%であった. また瀘胞癌の5年, 10年生存率は93.5%であった.今回は分子生物学的検討, 癌遺伝子の検討は行わなかったが, T1N0乳頭癌症例で頸部再発を認めたことから今後はこれらの検討も必要と考えられる.