著者

東辻 英郎 北村 溥之 齋藤 春雄 岸本 誠司 宮本 和雄

出版者

The Society of Practical Otolaryngology

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.74, no.4, pp.698-705, 1981

被引用文献数

2

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Sixteen patients with progressive bilateral perceptive deafness due to unknown causes were examined using various hearing tests and equilibrium tests with the following results.<br>1. Among the 11 patients examined 11 showed inner ear deafness and 3 showed inner ear deafness combined with retrocochlear one.<br>2. With reference to the appearance and progress of deafness, the deafness of this type was divided into the following two:<br>One was frequently observed in younger patients under twenty and was characterized by the tendency that bilateral deafness which appeared simultaneously and deteriorated equally, showed gradual, high-tone hearing loss. Thus, the hearing loss in these patients tended to be similar in pattern. i) between the first and the last examinations and ii) between the right and the left ears. Furthermore, the deafness of this type was rarely accompanied by vertiginous attacks.<br>The other was frequently found in older patients, of above twenty and was characterized by the tendency that deafness of both ears did not appear simultaneously and did not deteriorate equally. Furthermore, the deafness of this type was sometimes accompanied by vertiginous attacks in anamnesis.<br>3. Among the 16 patients examined, 4 showed fluctuating hearingloss. Furthermore, one of the 3 patients who underwent the glycerol test showed a positive sign. From the above mentioned findings the following conclusions were drawn:<br>(1) There may be differences between the 2 groups of patients, younger and older with regard to the etiological factors of the progressive bilateral perceptive deafness due to unknown causes, although both groups showed inner ear deafness. The deafness in the former group may be induced by congenital factors and may be regarded as a kind of premature presbyacusis. In contrast, the deafness in the later may be induced, at least partly, by acquired factors.<br>(2) Some patients showed findings suggestive of the existence of labyrinthine hydrops. These are valuable in considering the mechanism and treatment of the deafness of this type.

著者

三輪 高喜

出版者

The Society of Practical Otolaryngology

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.103, no.12, pp.1073-1081, 2010-12-01

被引用文献数

1

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Remarkable progress has been made in basic research on the sense of smell during the last few decades. This progress has been accelerated by the discovery made by Axel and Buck of the genes that encode olfactory receptors. These rescarchers won the Nobel Prize in Physiology or Medicine in 2004. The detection and discrimination of odor molecules in humans is mediated by 388 olfactory receptors that are expressed on olfactory sensory neurons. A basic understanding of the mechanism of odor reception is crucial to an understanding of olfactory dysfunction. Olfactory disorders can be classified as quantitative or qualitative disorders. The former category includes the deterioration or total loss of olfactory sensation, while the latter category includes distortions of the sense of smell. Quantitative olfactory disorders can be classified by the area affected by the disease into four major groups: (1) sino-nasal, (2) olfactory mucosa, (3) olfactory fila, and (4) central pathway. Chronic rhinosinusitis, which is the most frequent cause of olfactory disorders, is caused by the conductive loss of odor molecules. The second most common cause is postviral olfactory disorders occurring after an upper respiratory tract infection. The prognosis for olfactory function in individuals affected by these causes is relatively good. However, olfactory loss caused by neural disorders, such as posttraumatic olfactory loss, has a poor prognosis. Dysosmia, or a distorted sense of smell, is mainly caused secondary to postviral or posttraumatic olfactory disorders. Dysosmia is classified as either parosmia or phantosmia. Parosomia occurs in patients who are unable to correctly identify odors, while phantosmia involves the smelling of odors that are not derived from any physical stimulus. The mechanism of dysosmia has been clarified by basic research on olfactory reception and conduction.<br>

著者

原田 紀 川端 五十鈴 梅沢 久男 豊田 修

出版者

The Society of Practical Otolaryngology

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.59, no.12, pp.1027-1031, 1966

著者

川端 五十鈴 佐藤 恒正

出版者

The Society of Practical Otolaryngology

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.83, no.7, pp.1099-1110, 1990

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The lateralization of tinnitus on the cranium was measured by a directional hearing device, which can generate binaural time or intensity differences for various sound sources. Tracings of sound locomotion are recorded as sawteeth-like waves by repetition of the dial operation in the right and left directions.<br>First, the central and lateral sound images on the cranium were measured by method of adjustment for subjects with normal hearing. The range of the values was determined after three measurements per day for three days. The regions of these locations of sound impression were in close agreement, and 67% of 20 normal control subjects showed stable results.<br>Next, 30 subjects with normal hearing ability and monaural tinnitus were tested. The location of tinnitus on the cranium was determined after localization of the sound impression in the central and lateral positions by the method described above. The results were as follows: in 53% of the subjects the results were stable; 46% showed agreement between the positions of tinnitus and the lateral side, and 27% showed a more medial impression of tinnitus than the lateral position.<br>This method has no restrictions as a clinical test. The fact that the position of tinnitus may disagree with the lateral impression on the cranium was clarified by these experiments.

著者

菊地 茂 洲崎 春海 青木 彰彦 伊藤 修 野村 恭也

出版者

The Society of Practical Otolaryngology

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.84, no.1, pp.41-47, 1991

被引用文献数

41 27

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Twenty six adult patients with chronic sinusitis who had undergone Caldwell-Luc operation and received conservative therapy for a long time, but still complained of nasal symptoms, were treated with 400-600mg of erythromycin (EM) per day for 7.9 months on the average.<br>1) Rhinorrhea was reduced in 60.0%, postnasal drip in 50.0%, nasal obstruction in 60.0%, hyposmia in 11.8% and sense of dullness in the head in 100%.<br>2) Rhinoscopy showed reduced mucosal swelling in 10.5%, lower volume of rhinorrhea in 80.0%, better quality of rhinorrhea in 70.0% and reduced postnasal drip in 85.7%.<br>3) This therapy was effective even when EM-resistant bacteria such as Hemophilus influenzae were present.<br>4) No significant side effects were noted in any of the patients during this therapy. Long-term low-dose EM therapy is useful in the treatment of chronic sinusitis. We consider that its effect is not due to its antibacterial activity but to some as yet unknown mechanism.

著者

中江 進 水田 康雄 八木 美知 平杉 嘉昭 水越 治

出版者

The Society of Practical Otolaryngology

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.72, no.11, pp.1469-1477, 1979

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Five patients with a congenital deafness caused by maternal rubella infection during pregnancy visited our clinic in 1977. The ages ranged from 3 to 11 months. The diagnosis of deafness was made mainly by Brain Stem Response, partly startle response and C. O. R.<br>Case 1 was diagnosed as a typical congenital rubella syndrome, because of the high HI titer, congenital deafness, PDA+ASD, retinochoroidal degeneration, thrombocytopenia, and hepatosplenomegaly. Case 4 whose HI titer was high was accompanied by microphthalamia and anophthalamia with a positive response at 40dBSL in BSR the left ear and 50dBSL in the right ear.<br>We conclude that congenital deafness should be determined by Brain Stem Response as early as possible so that an early diagnosis of hearing impairment can be made.

著者

堀 龍介 安里 亮 田中 信子 嘉田 真平 平塚 康之 金子 賢一 児嶋 久剛 赤水 尚史 伊藤 壽一

出版者

The Society of Practical Otolaryngology

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.95, no.8, pp.825-829, 2002-08-01

被引用文献数

8 9

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Congenital piriform sinus fistula, which is usually unilateral, is recognized as a cause of acute suppurative thyroiditis. We have encountered a rare case of bilateral piriform sinus fistulae. The patient, a 53-year-old female, was referred to our hospital because of right neck swelling, which improved after conservative treat. Three months later, an abscess of the left thyroid lobe was presented and was improved after incision and drainage. The diagnosis of bilateral piriform sinus fistulae was made by hypopharyngeal enhancement radiography. Total fistulectomies were performed. There was no recurrence observed six months after surgery.

著者

野添 恒幹 和田 安弘 木下 卓也 熊沢 忠躬 浜田 栄幹

出版者

The Society of Practical Otolaryngology

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.78, no.6, pp.1041-1049, 1985

被引用文献数

1 1 3

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30才男性の両側性他覚的耳鳴を経験し, 耳鳴の発生に関与する筋および機序について検討した. その結果, 口蓋帆張筋間代性痙攣で耳管軟骨部内壁の急激な離開あるいは耳管周囲軟骨の変形が生じ, これが他覚的に click 音として聴取されたものと推定した. また本症例では口蓋帆張筋のみならず鼓膜張筋の間代性痙攣も確認された. 耳鳴時の鼓膜コンプライアンスの増大は鼓膜内陥運動と外耳道容積の増大とによるものと考えられた.

著者

国部 勇 野村 研一郎 野澤 はやぶさ 片田 彰博 今田 正信 小林 吉史 野中 聡 原渕 保明

出版者

The Society of Practical Otolaryngology

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.95, no.10, pp.1005-1009, 2002-10-01

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著者最終原稿版44歳男.以前に長管骨だけでなく頭蓋骨にも病変が及ぶことを報告したが,対象は同一家系内に発症した難聴をはじめとする多発性脳神経麻痺を呈したEngelmann症であった.主訴は難聴で右耳は伝音難聴,左耳は感音難聴を示していた.右耳においては所見上外耳道狭窄や中耳滲出液は認められず,耳小骨病変が難聴の主な原因であると考えられた.左耳ではCT所見で内耳道の直径が約2.5mmと右耳の4mmと比較して著明に狭窄していた.本症例の左感音難聴は内耳道狭窄が主な原因と考えて矛盾ないと考えられたが,SISIテストではリクルートメント陽性を示しており,内耳病変も少なからず関与している可能性も示唆された

著者

野澤 はやぶさ 國部 勇 柳内 充 片田 彰博 林 達哉 野中 聡 原渕 保明

出版者

The Society of Practical Otolaryngology

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.96, no.1, pp.9-13, 2003-01-01

被引用文献数

1

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Anti-phospholipid syndrome (APS) was first reported by Harris in 1985 as one of a variety of clinical features associated with episodes of arterial or venous thrombosis. We report a rare case of acute sensorineural hearing loss due to APS. A 40-year-old woman complained of acute sensorineural hearing loss. She had been diagnosed with APS because of positivity for serum anti-phospholipid antibody and 3 episodes of natural abortion. The hearing loss was improved by treatment with predonisolone, but after 4 months, hearing loss recurred. Since she refused steroid therapy and anticoagulation therapy, continuous administration of aspirin was performed. Six months later, her hearing had recovered. If a patient presents with sudden sensorineural hearing loss, it is important to suspect APS and inquire into histories such as thrombosis and recurrent abortion.

著者

駒林 優樹 野澤 はやぶさ 和田 哲治 金井 直樹 原渕 保明

出版者

The Society of Practical Otolaryngology

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.100, no.7, pp.559-563, 2007-07-01

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Lingual dermoid cysts are uncommon. To date, there have been twenty reported cases. We report an additional case of lingual dermoid cyst. The patient was a sixteen-year-old girl. She was referred to our clinic for painful tongue swelling. A firm, tender lingual mass with purulent drainage from the midline of the dorsum of the tongue was noted. After treatment with antibiotics and drainage, the size of the mass reduced gradually. Eight months later, regrowth of the mass was observed. The mass was totally excised via an oral and external approach. According to histopathological examination, the mass was diagnosed as dermoid cyst.

著者

原渕 保明 坂東 伸幸 高原 幹 岸部 幹 後藤 孝 野澤 はやぶさ 吉崎 智貴

出版者

The Society of Practical Otolaryngology

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.99, no.10, pp.805-812, 2006-10-01

被引用文献数

2 1

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Pustulosis palmaris et plantaris (PPP), Sterno-costo-claviclar hyperostosis (SCCH), IgA nephropathy, and some other autoimmune diseases have been regarded as tonsillar focal infections since tonsillectomy is quite effective in the treatment of these diseases. In this paper, we reviewed recent clinicopathological evidence on tonsillar focal infections obtained through our experience as well as in the literature. In addition, we summarized experimental results regarding mechanisms of the development and progression of tonsillar focal infections. It has been speculated that abnormal immune responses in the tonsils may cause or worsen the disease. Therefore, tonsillectomy should be recommended for the treatment of tonsillar focal infections.

著者

岸部 幹 吉野 和美 和田 哲治 金井 直樹 原渕 保明

出版者

The Society of Practical Otolaryngology

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.99, no.9, pp.795-800, 2006-09-01

被引用文献数

2

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著者版17歳男、前胸部痛、呼吸困難感を主訴とした。40〜60本/日の喫煙習慣があった。身長166cm、BMI 17.4であり、右側頸部に握雪感を伴う皮下気腫を認めた。胸部単純X線にて右鎖骨上窩の皮下気腫像を、頸・胸部CTにて右咽頭外側面〜胸鎖乳突筋裏面〜気管分岐部に気腫像を認めた。予防的にセフォペラゾンナトリウム:スルパクタムナトリウム合剤を開始したところ、前頸部から胸部の痛みは発症後2日で消失し、皮下気腫像は発症後6日目に消失した。食道造影、気管支ファイバーで異常はなく、特発性縦隔気腫と診断した。退院後43日目、誘引なく左頸部疼痛と呼吸困難感を認め、咳が多かった。CTにて左頸動脈間隙から胸鎖乳突筋裏面、鎖骨上窩、胸骨裏面、気管分岐部周囲、腹部大動脈周囲に気腫を認めた。後頸部から硬膜外ブピバカイン持続注入を開始したところ、翌日には疼痛、咳が消失した。また、セフォペラゾンナトリウム:スルパクタムナトリウムを7日間点滴した。気腫は消失し、禁煙を勧めて退院となった。以後、再発は認めなかった。

著者

森田 武志 藤木 暢也 倉田 響介 岡野 高之

出版者

The Society of Practical Otolaryngology

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.92, no.12, pp.1355-1357, 1999-12-01

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A 49-year-old male was treated for chronic tonsillitis with brachytherapy 40 years ago. The inflammation of the tonsils was improved by the treatment. On August 18th, 1998, he consulted our hospital complaining of sudden throat pain. The pain deviated to the left, intensified with eating and continued for several hours every day for one month. An X-ray revealed a metallic foreign body in his left tonsil. A left tonsillectomy was done on January 14th, 1999, and the foreign body was removed completely. It was a small gold tablet, 3×1×1mm in size. A scintillation counter proved that the metallic foreign body was a radon (²²⁰Rn) seed. This is a rare case of a radon seed buried in the left tonsil of a patient for 40 years.

著者

木村 貴昭 山中 昇 九鬼 清典 林 泰弘 斉藤 匡人 木下 和也 田村 真司 赤城 ゆかり 山本 良一 玉置 かおり 高野 郁晴 保富 宗城 戸川 彰久 山室 日出子 島田 純 藤原 啓次 寒川 高男 神人 崇

出版者

The Society of Practical Otolaryngology

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.90, no.1, pp.121-130, 1997-01-01

被引用文献数

2

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A comparative study was performed for the purposes of studying the prophylactic effectiveness of an antecedent treatment for Japanese cedar pollinosis with DAREN^® (emedastine difumarate), an anti-allergic drug. Thirty-five cases (A group) received the drug at 4mg/day at least 2-4 weeks before the day when the pollen began to scatter. Another thirty-nine patients received the treatment after the scattering (B group). A significant inter group difference was observed in the global improvement rate for pollinosis. These findings suggest that DAREN^® produces a slow, long-acting effect such as the inhibition of the release of chemical mediators. Prophylactic medication seems to be suitable for the treatment of Japanese cedar pollinosis, because sufficient anti-allergic action is obtained a few weeks later. Side effects occurred in 6.9% of all of the cases, but the incidence was lower than with any other anti-allergic drug previously reported.<br>In summary, a prophylactic treatment with DAREN^® is effective in treating Japanese cedar pollinosis.

著者

深本 克彦 市川 銀一郎

出版者

The Society of Practical Otolaryngology

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.88, no.6, pp.773-779, 1995-06-01

被引用文献数

30 11

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Advanced deep neck infection (ADNI) can spread into spaces and cause death rapidly. In 1990 we reported a case of ADNI secondary to tonsillitis, with general deterioration due to duodenal perforation and liver cirrhosis. Since then there have been also many case reports on ADNI, and which some patients have died.<br>To determine the rational treatment of ADNI, 55 cases were collected from the literature in Japan and were analyzed statistically.<br>It was conclusions that the most important point is the prevention of the spread of infection, especially downward into the mediastinum. Drainage by a vertical incision is useful, and effective antibiotics must be administered such as clindamycin, lincomycin, cefmetazole, sulbenicillin or imipenem/cilastacin. Special care is needed in the treatment of elderly patients and those with diabetes other diseases in which immunity is reduced.