著者

奥山 喜久夫 I. Wuled LENGGORO

出版者

The Society of Powder Technology, Japan

雑誌

粉体工学会誌 (ISSN:03866157)

巻号頁・発行日

vol.37, no.10, pp.753-760, 2000-10-10 (Released:2010-04-30)

参考文献数

28

被引用文献数

6 5

著者

打越 進 野村 公寿 木村 廣行 宇佐 神篤

出版者

The Oto-Rhino-Laryngological Society of Japan, Inc.

雑誌

日本耳鼻咽喉科学会会報 (ISSN:00306622)

巻号頁・発行日

vol.84, no.4, pp.374-378, 1981-04-20 (Released:2008-03-19)

参考文献数

12

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Six patients with nasal allergy due to Japanese Apricot pollen which are called "Ume" pollen were clinically examined. All cases had hyperrhinorrhea and nasal obstruction with ocular symptoms, and one of them also had itching in the pharynx. They have lived for 8 to 47 years near by a large grove of Japanese apricot and 4 of them were fruit-growers. Among these four cases, three have suffured from nasal and ocular symtoms while they were working in the grove. These cases had positive skin reaction to clude "Ume" pollen extract, and five patients also reacted to nasal and ocular provocative tests.Serum IgE value by RIST was distributed from 98 to 2300IU/ml (mean value 887IU/ml). Specific anti-"Ume" pollen IgE in the serum was measured by BrCN activated RAST method, and serum value of five patients was 1.6 timed to 3.5 times higher than that of non-allergic subjects.Air-borne "Ume" pollen collected in a grove were observed from the beginning of February to the middle of March, and maximum grain count was 43 per cm2 in 24 hours.

著者

梅基 直行 水谷 正治 村中 俊哉

出版者

公益社団法人 日本農芸化学会

雑誌

化学と生物 (ISSN:0453073X)

巻号頁・発行日

vol.56, no.8, pp.566-572, 2018-07-20 (Released:2019-07-20)

参考文献数

32

著者

田中 敏郎

出版者

日本臨床免疫学会

雑誌

日本臨床免疫学会会誌 (ISSN:09114300)

巻号頁・発行日

vol.38, no.4, pp.291b, 2015

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現在,関節リウマチ,若年性特発性関節炎,キャスルマン病に対する治療薬として承認されているヒト化抗IL-6受容体抗体トシリズマブは,他の様々な慢性に経過する免疫難病にも新たな治療薬となる可能性があり,臨床試験が進められている.また,最近,キメラ抗原受容体を用いたT細胞療法に合併するサイトカイン放出症候群にもトシリズマブが著効することが示され,IL-6阻害療法は,サイトカインストームを呈する急性全身性炎症反応に対しても新たな治療手段となる可能性がある.サイトカインストームには,サイトカイン放出症候群,敗血症ショック,全身性炎症反応症候群,血球貪食症候群やマクロファージ活性化症候群など含むが,特に敗血症ショックでは,病初期のサイトカインストームとその後の二次性の免疫不全状態により,予後が極めて悪く,しかし有効な免疫療法がないのが現状である.敗血症患者ではIL-6は著増し,IL-6の血管内皮細胞の活性化,心筋抑制や凝固カスケードの活性化等の多彩な作用,また,同様な病態を呈するサイトカイン放出症候群に対するトシリズマブの劇的な効果を見ると,IL-6阻害は敗血症に伴う多臓器不全に対して有効な治療法となる可能性がある.しかし,現在,トシリズマブは重篤な感染症を合併している患者には禁忌であり,どのように挑戦するのか,症例(報告)の解析,患者検体,動物モデルを用いた我々のアプローチを紹介したい.

著者

山川惣治 著

出版者

集英社

巻号頁・発行日

vol.赤ゴリラ篇, 1948

著者

加藤 公太

出版者

順天堂大学

巻号頁・発行日

2018

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終了ページ : 42

著者

色川 豪一 Hidekazu IROKAWA

巻号頁・発行日

no.1, pp.105-119, 2020-03-07

著者

浜本浩 著

出版者

第百書房

巻号頁・発行日

1935

著者

浜本浩 著

出版者

文松堂

巻号頁・発行日

1942

著者

浜本浩 著

出版者

輝文館

巻号頁・発行日

1941

著者

保坂 武志

出版者

The Human Geographical Society of Japan

雑誌

人文地理 (ISSN:00187216)

巻号頁・発行日

vol.42, no.5, pp.427-441, 1990-10-28 (Released:2009-04-28)

参考文献数

54

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Central place theory(CPT) is built with assumptions that traffic condions and demand distribution are uniform. These assumptions are usually not met in the real world. The purpose of this paper is to detect the hexagonal arrangement of hinterlands implied in CPT by transforming the real world into an uniform surface, mainly focusing on demand distrition.The transformation of the real world into an iso-demand surface is called “map transformation” (Getis, 1963; Rushton, 1972). However, these previous studies have paid no attention to traffic conditions. The idea adopted in this paper is as follows: if boundaries of hinterlands, which are influenced by traffic conditions, were transformed on an iso-demand surface, the resulting areas of hinterlands will meet the above two assumptions. In order to perform this “map transformation”, an area cartogram is used, whose algorithm is developed according to Dugenik et al. (1985).Public baths are taken as an example of emprical work; their patrons are behaved as if the nearest center hypothesis is confirmed (see Fig. 4), so that boundaries of their hinterlands are easily demarcated using the Thiessen polygons defined around their locations. The study area is the northwestern part of Tokyo City in 1970 where demand and supply of public baths seem to have been well balanced then; CPT assumes that the balance of demand and supply is kept.Comparing the iso-demand surface (Fig. 7) with the real world (Fig. 3) reveals that variance of areas of hinterlands in the former is much smaller than that in the latter (see Fig. 8). The result of map transformation analysis also suggests that the study area is divided into two districts in terms of goodness-of-fit, which can be differentiated according to the urbanization level in 1970.The first is the district already developed by 1970-most part of Toshima, Shinjuku, and Nakano Words. The developed district consists of two types of residential areas: residential quarters with detached houses, such as Ochia'i district, and built-up areas with wooden apartments. While in the real world the areas of hinterlands in the former residential areas are much larger than those in the latter, the both areas are nearly equal in the iso-demand surface; there is relatively less demand for public baths in the former residential areas where a lot of high-class houses had been built with a bathroom, and so people were less densely inhabited compared with the latter residential areas. It seems that demand and supply of public baths were belanced in each different type of residential areas.The second is the developing district, the nortwestern part of the study area. Its hinterland areas are larger than the areas in the developed district, even on the iso-demand surface, which is due to an imbalance of demand and supply.In sum, this paper has illustrated that hinterlands can be arranged in the manner prescribed by CPT if its all the assumptions are met.

著者

原田 幸明 菅 広雄

出版者

Japan Society of Powder and Powder Metallurgy

雑誌

粉体および粉末冶金 (ISSN:05328799)

巻号頁・発行日

vol.33, no.2, pp.63-68, 1986-02-25 (Released:2009-05-22)

参考文献数

16

被引用文献数

1 1

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Some of the processing parameters for centrifugal atomization of molten metal were studied by means of a model-experiment using water.The shape and revolution velocity of the high speed rotating stages affected the size and the scattering distribution of disintigrated droplets. In the atomization using a flat stage, liquid disintegrated into smaller particles but sticked considerably to the wall of the apparatus. Conical type stages lessened the sticking and increased the portion of the larger drops slightly. Higher velocity revolution made finer particles and narrowed the scattering range of drops at the bottom of the chamber closely to the center. The wettability of the liquid on the stage surface was found to be an important factor for the disintegration of the liquid. Enhanced wettability brought direct drop formation, while poor wettability brought ligament disintegration.

著者

横田,祥

出版者

日本流体力学会

雑誌

日本流体力学会年会講演論文集

巻号頁・発行日

vol.2010, 2010-09-09

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In the terrestrial and planetary atmospheres, vortices that exhibit a polygonal shape are occasionally observed even when the external conditions are nearly axisymmetric. Similar phenomena are also found in laboratory experiments in which water layer in a right cylindrical tank is driven by a rapidly-rotating bottom disk. In this study, we have studied these phenomena by means of laboratory experiments and a linear stability theory. It is found that the characteristics of the vortices in the laboratory experiments are well explained by those of the fastest growing waves caused by a horizontal shear instability of the basic flow. Thus, the polygons observed in the laboratory experiments are likely to be caused by a shear instability.

著者

仲矢 信介

出版者

早稲田大学大学院文学研究科

雑誌

早稲田大学大学院文学研究科紀要. 第3分冊 (ISSN:13417533)

巻号頁・発行日

vol.47, pp.91-102, 2001

著者

仲矢 信介

出版者

三元社

雑誌

ことばと社会

巻号頁・発行日

no.6, pp.60-76, 2002

著者

秦 正樹 宮前 真 塩入 重彰 村上 和裕 中林 晋也 大山 哲生 原口 美穂子 服部 麻里子 中島 純子 皆木 祥伴 藤原 茂弘 小野 高裕

出版者

一般社団法人 日本顎顔面補綴学会

雑誌

顎顔面補綴 (ISSN:03894045)

巻号頁・発行日

vol.42, no.1, pp.33-38, 2019 (Released:2020-03-12)

参考文献数

31

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Background: The aim of this review was to elucidate the effectiveness of prostheses with implant therapy for patients with mandibular defects.Methods: A systematic literature survey was conducted by the Japan Medical Library Association based on keywords for PubMed and Ichushi-web presented by the Clinical Practice Guideline Committee of Japanese Academy of Maxillofacial Prosthetics. After the secondary screening, related articles were extracted and their structured abstracts were described for discussion.Results: Although randomized controlled trials and meta-analyses were not found, 28 papers were extracted after screening. Overall, objective and subjective measures (e.g. occlusal force, masticatory efficiency and food acceptability questionnaires) were significantly increased with implant-supported mandibular prostheses. However, speech and swallowing function were not improved in cases with tongue or oral floor resection. Success and survival rates of implant therapy were ninety percent or more on mandibular reconstruction with autogenous bone grafts.Conclusions: These results suggest that implant-supported mandibular prostheses that can secure the stability of the upper fixed/removable structure are more effective for recovering masticatory function compared with conventional mandibular prostheses.

著者

佐々木 紘一 本藤 裕 岸井 利昭

出版者

公益社団法人 日本人間ドック学会

雑誌

健康医学 (ISSN:09140328)

巻号頁・発行日

vol.19, no.4, pp.551-555, 2004-12-20 (Released:2012-08-27)

参考文献数

7

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目的:人間ドックの尿定性検査について特に尿潜血反応はどこからを有意ととるべきかについて検討する方法:神奈川県労働衛生福祉協会で,平成14年10月1日~15年9月30日の間に人間ドックを受けた男性3,685人,女性1,811人,計5,496人の尿定性所見について検討した.結果:尿潜血+以上の陽性率は,男性13.1%,女性32.2%であった.また,尿潜血2+以上としたときの陽性率は,男性4.4%,女性14.4%であった.尿蛋白+以上の陽性率は,男性5.5%,女性2.3%であった.尿糖+以上の陽性率は,男性1.3%,女性0.3%であった.結論:腎機能障害は,尿潜血陽性率よりも,尿蛋白陽性率との間により関連性があると思われた.現在用いられている試験紙による方法では,尿潜血反応2+以上を有意と判定するのが妥当と思われた.尿潜血反応+の場合,まず尿沈渣を調べ,赤血球が少数のときは軽度異常とすべきである.尿中赤血球5-6/HPFが尿潜血反応+に相当するような尿試験紙があれば,最も理想的であろう.

著者

林 安紀子

出版者

日本音声学会

雑誌

音声研究 (ISSN:13428675)

巻号頁・発行日

vol.7, no.2, pp.29-34, 2003-08-30 (Released:2017-08-31)

被引用文献数

1

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In this paper, several studies about infants' ability to discriminate languages between birth and 4-5 months were reviewed. In the rhythmic class acquisition hypothesis, infants' initial sensitivity to rhythmic classes would allow them to specify the common rhythmic properties of their native rhythmic class, and from this they would develop an associated metrical segmentation procedure. In addition,several studies about American infants' ability to extract word-like units from fluent speech were reviewed. Finally, several studies about Japanese infants' sensitivity to the typical rhythm pattern based on morae of Japanese baby words were reviewed.

著者

クンチョック シィター

雑誌

日本西蔵学会々報

巻号頁・発行日

no.39, pp.25-33, 1993

著者

壼井 基夫

出版者

公益社団法人 日本農芸化学会

雑誌

化学と生物 (ISSN:0453073X)

巻号頁・発行日

vol.16, no.1, pp.10-15, 1978-01-25 (Released:2009-05-25)

参考文献数

25