著者
Celik Ozlem Buyuktas Deram Sevinc Mustafa Tascilar Koray Demirkesen Cuyan Tasan Ertugrul
出版者
The Japanese Society of Internal Medicine
雑誌
Internal Medicine (ISSN:09182918)
巻号頁・発行日
vol.50, no.18, pp.1973-1976, 2011 (Released:2011-09-15)
参考文献数
15
被引用文献数
6 8

Propylthiouracil (PTU) is an antithyroid drug which is known to cause drug-induced vasculitis. PTU is implicated in 80-90% of cases of anti-neutrophil cytoplasm circulating antibody (ANCA)-associated vasculitis caused by anti-thyroid drugs which induce ANCA production. Sweet's syndrome is characterized by fever, leucocytosis, neutrophilia and the sudden onset of painful skin lesions. The pathology of the disease is still unclear. Cytokine dysregulation including interleukin-6 and endogenous granulocyte colony-stimulating factor (G-CSF) are thought to play a role in the pathogenesis of Sweet's syndrome. PTU and G-CSF are known to cause Sweet's syndrome and other neutrophilic dermatosis. The presence of ANCA can have a diagnostic value in Sweet's syndrome. Systemic corticosteroids are the first-line therapy for both diseases. Here we report a female patient with Graves' disease who developed ANCA and Sweet's syndrome after using PTU and G-CSF.
著者
佐々木 将人
出版者
日本経営学会
雑誌
日本経営学会誌 (ISSN:18820271)
巻号頁・発行日
vol.29, pp.41-53, 2012

This paper examines the effect of horizontal coordination mechanisms on coordination activity in organizations and the moderating effect of organizational differentiation. In classical research, such as the contingency theory of organizations and information processing view, horizontal coordination mechanisms are effective coordination devices for organizations. In particular, to integrate differentiated functions, horizontal coordination mechanisms are treated as crucially important. However, recent studies indicate the cost of these coordination mechanisms and emphasize the importance of organizational consensus. Based on these theoretical gaps, this paper investigates the relationships among horizontal coordination mechanisms, organizational differentiation, and organizational performance in the SBUs of Japanese companies. The result shows that (1) horizontal coordination mechanisms have a negative impact on organizational coordination activity, (2) increasing functional differentiation strengthens this relationship, and (3) increasing hierarchical differentiation weakens this relationship. These findings indicate that the functions of horizontal coordination mechanisms are different in SBUs and functional organizations.
著者
Kuzuhara Shigeki
出版者
日本神経学会
雑誌
臨床神経学 (ISSN:0009918X)
巻号頁・発行日
vol.49, no.11, pp.968-971, 2009 (Released:2009-12-28)
参考文献数
4
被引用文献数
1 2

The first medical society of Japanese neurologists and psychiatrists was founded in 1902, but psychiatrists gradually dominated in number. New "Japanese Society of Neurology" (JSN) was founded in 1960. The number of members was only 643 in 1960, while it rose up to 8,555 in 2009, including regular, junior, senior and associate members. JSN contributed much to solve the causes and treatment of the medicosocial and iatrogenic diseases such as Minamata disease and SMON (subacute myelopticoneuropathy) at its early period. In undergraduate education at medical school, neurology is one of the core subjects in the curriculum, and almost all the 80 medical schools have at least one faculty neurologist. The Board of neurology of JSN was started in 1975, as the third earliest of the Japanese Medical Associations. It takes at least 6 years' clinical training after graduating from the medical school to take the neurology Board examinations. By 2009, 4,000 members passed the Board examinations. In 2002 JSN published evidence-based "Treatment Guidelines 2002" of 6 diseases: Parkinson's disease, stroke, chronic headache, dementia and ALS. As to the international issues, JSN hosted the 12th World Congress of Neurology in 1981, and international activities markedly increased after that. The first informal meeting with JSN and Korean Neurological Association (KNA) was held at the 48th JSN Annual Meeting in Nagoya in May 2007. In May 2008 the KNA-JSN 1st Joint symposium was held at the 49th Annual Meeting of JSN in Yokohama on "International comparison of neurological disorders: focusing on spinocerebellar atrophies (SCA) and epilepsies". In May 2009, KNA-JNS 2nd Joint Symposium was held at the 50th JSN Annual Meeting in Sendai, inviting a speaker from Taiwan Neurological Society, on the subject "History and Education of Neurology in Japan, Korea and Taiwan". In this symposium, a strategy to make up the Northeast Asian Neurological Association was discussed.
著者
岩熊 幸男
出版者
京都大学人文科学研究所
雑誌
人文学報 (ISSN:04490274)
巻号頁・発行日
no.60, pp.p105-160, 1986-03

3 0 0 0 OA 官報

著者
大蔵省印刷局 [編]
出版者
日本マイクロ写真
巻号頁・発行日
vol.1926年12月18日, 1926-12-18

3 0 0 0 OA 作詩大成

著者
井土霊山 著
出版者
崇文館
巻号頁・発行日
1911

3 0 0 0 OA 官報

著者
大蔵省印刷局 [編]
出版者
日本マイクロ写真
巻号頁・発行日
vol.1914年06月01日, 1914-06-01
著者
Masashi KOMORI Hiroko KAMIDE Satoru KAWAMURA Chika NAGAOKA
出版者
The Institute of Electronics, Information and Communication Engineers
雑誌
IEICE TRANSACTIONS on Information and Systems (ISSN:09168532)
巻号頁・発行日
vol.E96-D, no.3, pp.507-513, 2013-03-01

This study investigated the relationship between social skills and facial asymmetry in facial expressions. Three-dimensional facial landmark data of facial expressions (neutral, happy, and angry) were obtained from Japanese participants (n = 62). Following a facial expression task, each participant completed KiSS-18 (Kikuchi's Scale of Social Skills; Kikuchi, 2007). Using a generalized Procrustes analysis, faces and their mirror-reversed versions were represented as points on a hyperplane. The asymmetry of each individual face was defined as Euclidian distance between the face and its mirror reversed face on this plane. Subtraction of the asymmetry level of a neutral face of each individual from the asymmetry level of a target emotion face was defined as the index of “expression asymmetry” given by a particular emotion. Correlation coefficients of KiSS-18 scores and expression asymmetry scores were computed for both happy and angry expressions. Significant negative correlations between KiSS-18 scores and expression asymmetries were found for both expressions. Results indicate that the symmetry in facial expressions increases with higher level of social skills.
著者
酒向慎司 宮島千代美;徳田恵一 北村正 北村 正
出版者
一般社団法人情報処理学会
雑誌
情報処理学会論文誌 (ISSN:18827764)
巻号頁・発行日
vol.45, no.3, pp.719-727, 2004-03-15
参考文献数
16
被引用文献数
19

隠れマルコフモデルに基づく音声合成方式を歌声合成に拡張することにより構築した歌声合成システムについて述べる.本システムでは,歌い手の声の質と基本周波数パターンに関する特徴をモデル化するため,スペクトルと基本周波数パターンをHMMにより同時にモデル化している.特に,自然な歌声を合成するうえで重要な要素となる音符の音階や音長の基本周波数パターンへの影響を精度良くモデル化するため,楽譜から得られる音階と音長を考慮したコンテキスト依存モデルを構築している.これらのモデルに対して決定木によるコンテキストクラスタリングを行うことで,未知の楽曲からの歌声合成が可能となっている.実験から,歌い手の特徴を再現し歌声の合成が可能であることを示す.We describe a singing voice synthesis system by applying HMM-basedspeech synthesis technique.In this system, a sequence of spectrum and F0 are modeledsimultaneously in a unified framework of HMM, and context dependentHMMs are constructed by taking account of contextual factors thataffects singing voice.In addition, the distributions for spectral and F0 parameter areclustered independently by using a decision-tree based contextclustering technique.Synthetic singing voice is generated from HMMs themselves by usingparameter generation algorithm. In the experiments, we confirmed that smooth and natural-soundingsinging voice is synthesised. It is also maintains the characteristicsand personality of the donor of the singing voice data for HMMtraining.
著者
京都大学図書館業務改善検討委員会 図書館サービス部会
出版者
京都大学図書館業務改善検討委員会 図書館サービス部会
巻号頁・発行日
2014-08-01

図書館資料保存環境整備マニュアル(書庫環境編)2015年度は以下URLを参照 http://hdl.handle.net/2433/198883
著者
須藤 陽子
出版者
立命館大学法学会
雑誌
立命館法學 (ISSN:04831330)
巻号頁・発行日
vol.2007, no.4, pp.983-1005, 2007
著者
須藤 陽子
出版者
立命館大学法学会
雑誌
立命館法學 (ISSN:04831330)
巻号頁・発行日
vol.2007, no.2, pp.251-279, 2007
著者
浜中 保三 前田 省吾 赤岩 道夫 岸川 央 沢江 義郎 冨永 喜久男
出版者
一般社団法人 日本血液学会
雑誌
臨床血液 (ISSN:04851439)
巻号頁・発行日
vol.15, no.8, pp.898-903, 1974 (Released:2008-10-31)
参考文献数
8

A 29 years old male patient of Lymphosarcoma with two kinds of M-Components has been described.The patient had been admitted to Shin Kokura Hospital because of lymphadenopathy of cervical, axillar and inguinal area. Biopsy of the cervical lymph node has revealed the histological finding of Lymphosarcoma.During the course of therapy with corticosteroid hormone and cyclophosphamide, two kinds of M-components had appeared in the patient's serum, and had been identified as IgG·κ and IgM·κ by immunoelectrophoresis.Serum concentration of the patient's immunoglobulin had increased three times for IgG and approximately ten times for IgM by antibody agar plate method.In ultracentrifugal analysis, however, there had been no increase of 19S component although 7S component had shown remarkable increase.The dyscrepancy between immunological measurement and ultracentrifugal analysis has been explained by the appearance of IgM with smaller molecular size than usual 19S-IgM. After clinical course of some thirty days the IgM concentration had come down to normal range accompanying the disappearance of monoclonal IgM in immunoelectrophoresis.The mechanism of the appearance of the two kinds of M-components, one of which was transient, has been discussed.
著者
山内 健治 仲座 栄三
出版者
明治大学
雑誌
基盤研究(C)
巻号頁・発行日
2009

沖縄県下における台風・暴風・雨・干ばつなど、主に気象環境を、民俗レベルで、人々が観察し、予兆してきたかの民俗知識のデータベース化を意図した研究の一環である。同県の市町村史・誌、字史・誌に記録された気象に関する民俗知識・予兆伝承をリストアップしデータベース化した。また、気象予兆知識が実際に機能しているか、村落社会の中で語られているのかを確認するためにインテンシブな民俗調査を実施した。