著者
石黒 要 今井 哲也 品川 誠
出版者
Japan Surgical Association
雑誌
日本臨床外科学会雑誌 (ISSN:13452843)
巻号頁・発行日
vol.66, no.7, pp.1639-1642, 2005-07-25 (Released:2009-01-22)
参考文献数
20
被引用文献数
1

症例は68歳,女性.慢性関節リウマチのため10年以上プレドニゾロン10mg/日を服用していた. 2003年9月18日,腹痛を認め救急車にて搬送された.腹部CT検査にて小腸穿孔・汎発性腹膜炎と診断,手術を施行した.回盲部より30cm口側の回腸に穿孔を認め,小腸切除術を施行した.病理組織学的検査では,潰瘍底にカンジダの増殖を伴う潰瘍を2カ所に認め,うち一方が穿孔していた.医学中央雑誌で過去10年間を検索したが,カンジダによる成人の小腸穿孔の報告はなかった.カンジダは易感染性の患者に日和見感染症を起こし重篤になる場合がある.小腸カンジダ症は稀ではあるが,潰瘍や穿孔の一因になりうるということを,再度認識する必要があると思われた.
著者
Takahito Kajiki Shiro Komba
出版者
The Japanese Society of Applied Glycoscience
雑誌
Journal of Applied Glycoscience (ISSN:13447882)
巻号頁・発行日
vol.66, no.3, pp.103-112, 2019-08-20 (Released:2019-08-28)
参考文献数
20
被引用文献数
6

We have developed a novel low-molecular-mass oil-gelling agent that is electrically neutral, has no nitrogen atoms and consists only of cyclic sugar alcohols and saturated linear fatty acids. The cyclic sugar alcohols were 1,5-anhydro-D-glucitol (1,5-AG) and 1,5-anhydro-D-mannitol (1,5-AM) derived from starch via 1,5-anhydro-D-fructose. Various saturated linear fatty acids with 10 to 18 and 22 carbon atoms were introduced into all the hydroxy groups of 1,5-AG. Various saturated linear fatty acids with 13 to 18 and 22 carbon atoms were introduced into all the hydroxy groups of 1,5-AM. Initially, the gelling ability increased as the carbon number increased, but the gelling ability decreased as the carbon number increased beyond 17 carbons. This trend was similar for both 1,5-AG and 1,5-AM. A comparison of 1,5-AG and 1,5-AM derivatives revealed that 1,5-AG derivatives had greater gelling abilities for different kinds of oils at the same fatty acid length. Further, it was confirmed by SEM observations that a three-dimensional fibrous structure was formed, and this network structure formed the gel and held the oil. Here, we report the synthesis and characteristics of a novel low-molecular-weight gelling agent and its gelation mechanism.
著者
Junko Matsuki Masahisa Wada Tomoko Sasaki Koichi Yoza Ken Tokuyasu
出版者
The Japanese Society of Applied Glycoscience
雑誌
Journal of Applied Glycoscience (ISSN:13447882)
巻号頁・発行日
vol.66, no.3, pp.97-102, 2019-08-20 (Released:2019-08-28)
参考文献数
28
被引用文献数
3

Ethanol precipitation process for purification of branched dextrin (BD) in Nägeli amylodextrin from waxy rice starch was developed. Temperature and ethanol concentration for precipitation were main parameters affecting the recovery and purity of BD, and the purification condition at 4 °C and 10 % (v/v) ethanol in water was adopted. After four-time precipitation, the BD recovery was 34.6 %, whereas the purity improved from 78.5 % at the initial to 94.5 % at the four-time purified BD (BD4). BD4 mainly showed a chain length distribution between 18 to 35 with a mode length of 25, which shifted after enzymatic debranching with isoamylase to that between 9 and 20 with a mode length of 14. Each purified BD was solubilized in water, and each solution was mixed with methanol-water at 25 °C to a final methanol concentration of 16 M. The flakes of BD precipitated with 16 M methanol exhibited an A-type crystal structure by an X-ray diffraction analysis, and the speed generation of white flakes in 16 M methanol dramatically increased as the purification time increased. The effect of addition of highly branched cyclic dextrin (HBCD) or sodium tetraborate on BD aggregation in 16 M methanol was also investigated, where the former retarded aggregation but the latter had no effect on the velocity. Thus, the purified BD enables rapid characterization of aggregation of double helix structures of A-type crystal structure, and screening of compounds which could affect the phenomena for prediction of potentials in starch modification as well.
著者
Kiyoshi Kawai Iyo Uneyama Savitree Ratanasumawong Yoshio Hagura Ken Fukami
出版者
The Japanese Society of Applied Glycoscience
雑誌
Journal of Applied Glycoscience (ISSN:13447882)
巻号頁・発行日
vol.66, no.3, pp.89-96, 2019-08-20 (Released:2019-08-28)
参考文献数
33
被引用文献数
6

Glass transition temperature (Tg) is an important parameter for the physical quality control of hard candies. In order to understand the applicability of calcium maltobionate to hard candy, effect of calcium maltobionate addition on the Tg of model and hand-made hard candies was investigated. Freeze-dried calcium maltobionate-sugar (sucrose containing a small amount of glucose-fructose mixture) and calcium maltobionate-reduced isomaltulose mixtures were prepared as model candies, and their anhydrous Tg was evaluated using a differential scanning calorimetry. The anhydrous Tg increased linearly with the molar fraction of calcium maltobionate. From these results, it was expected that calcium maltobionate can improve the physical stability of normal and sugarless candies. For comparison, various commercial candies were employed, and their Tg was evaluated using a thermal rheological analysis. The Tg values were in the range of 28–49 °C. The Tg values were higher than 25 °C, which is significant with respect to the physical stability of the candies. Calcium maltobionate-sugar and calcium maltobionate-reduced isomaltulose candies were prepared as hand-made candies. The calcium maltobionate-reduced isomaltulose candies had higher Tg than the calcium maltobionate-sugar candies at each calcium maltobionate content, although reduced isomaltulose has a lower Tg than sugar. At a high calcium maltobionate content, calcium maltobionate-reduced isomaltulose candy had an equivalent Tg to the commercial sugarless candies, and thus practically acceptable stability was expected. In the case of calcium maltobionate-sugar candies, there was a possibility that the hydrolysis of sugar reduced their Tg. Vacuum-concentration will be useful to improve the Tg of the candies.
著者
Naoki Shirasaka Koichi Harazono Ryota Nakahigashi Keigo Mitsui Jun Tanaka Sayaka Tanazawa Masaru Mitsutomi Takayuki Ohnuma
出版者
The Japanese Society of Applied Glycoscience
雑誌
Journal of Applied Glycoscience (ISSN:13447882)
巻号頁・発行日
vol.66, no.3, pp.83-88, 2019-08-20 (Released:2019-08-28)
参考文献数
29
被引用文献数
2

We characterized SaHEX, which is a glycoside hydrolase (GH) family 20 exo-β-N-acetylhexosaminidase found in Streptomyces avermitilis. SaHEX exolytically hydrolyzed chitin oligosaccharides from their non-reducing ends, and yielded N-acetylglucosamine (GlcNAc) as the end product. According to the initial rate of substrate hydrolysis, the rates of (GlcNAc)3 and (GlcNAc)5 hydrolysis were greater than the rates for the other oligosaccharides. The enzyme exhibited antifungal activity against Aspergillus niger, which was probably due to hydrolytic activity with regard to chitin in the hyphal tips. Therefore, SaHEX has potential for use in GlcNAc production and food preservation.
著者
三沢 岳志 小池 秀雄 小林 和人
出版者
一般社団法人 情報科学技術協会
雑誌
情報プロフェッショナルシンポジウム予稿集 第16回情報プロフェッショナルシンポジウム
巻号頁・発行日
pp.73-77, 2019 (Released:2019-06-14)

特許出願の件数の推移は、その特許出願が技術的に関連する製品の出荷台数推移や製品のライフサイクルステージと大きな相関を持つことが考えられる。本稿では、明細書にその応用製品が記載された特許出願の件数推移とその将来予測、製品コア技術の特許出願件数推移とその将来予測から、製品の将来の出荷台数を予測することで、製品ライフサイクルステージの特定が可能であることを示す。なお予測の基本方式としては、それぞれの特許出願件数推移にBassモデルによる近似式を適用した。現状では市場の状況の事後的な把握でしか確認することのできない製品ライフサイクルステージを、知的財産の情報に基づいて予測できれば、知的財産戦略の立案にも有効であるとともに、事業戦略の転換時期の決定においても参考にもなるものと考える。
著者
木元 裕介 進藤 伸一 KIMOTO Yusuke SHINDO Shinichi
出版者
秋田大学大学院医学系研究科保健学専攻
雑誌
秋田大学大学院医学系研究科保健学専攻紀要 (ISSN:18840167)
巻号頁・発行日
vol.19, no.2, pp.127-133, 2011-10-01

【目的】ハムストリングスに対するスタティックストレッチング(以後, ストレッチング) 施行後の筋力と関節可動域の時間的変化を検討した.【方法】同意を得た16名を対象にストレッチングは30秒間を3回施行した. 測定は膝関節屈曲筋力と膝関節伸展関節可動域をストレッチング前, ストレッチング直後, ストレッチング後5分, 10分, 15分に測定した. また,ストレッチングをしない場合の測定も行った.【結果】筋力はストレッチング直後に有意に減少し, ストレッチング後5分に元に戻っていた. 関節可動域はストレッチング直後に有意に増加し, 10分後に元に戻っていた.【考察】近年の研究によりストレッチングは筋力を低下させると報告されており, 本研究でも筋力の低下がみられた.しかし, その低下は一時的で短時間なものだった. また, ストレッチングによって変化した筋力と関節可動域が元に戻る時間にずれがあることがわかった.
著者
橋本 すみれ 地野 充時 来村 昌紀 王子 剛 小川 恵子 大野 賢二 平崎 能郎 林 克美 笠原 裕司 関矢 信康 並木 隆雄 寺澤 捷年
出版者
一般社団法人 日本東洋医学会
雑誌
日本東洋醫學雜誌 = Japanese journal of oriental medicine (ISSN:02874857)
巻号頁・発行日
vol.60, no.2, pp.171-175, 2009-03-20
参考文献数
13
被引用文献数
2

線維筋痛症による全身の疼痛に対し,白虎湯加味方が有効であった症例を経験した。症例は65歳女性。自覚症状として,夏場に,あるいは入浴などで身体が温まると増悪する全身の疼痛および口渇,多飲があり,身熱の甚だしい状態と考えて,白虎湯加味方を使用したところ全身の疼痛が消失した。線維筋痛症に対する漢方治療は,附子剤や柴胡剤が処方される症例が多いが,温熱刺激により全身の疼痛が悪化する症例には白虎湯類が有効である可能性が示唆された。
著者
川端 由美子
出版者
日本労務学会
雑誌
日本労務学会誌 (ISSN:18813828)
巻号頁・発行日
vol.19, no.1, pp.26-42, 2018-05-01 (Released:2018-12-27)
参考文献数
44

This study examines the human resources management systems for spousal transfers, including workplace transfer programs, administrative leave for trailing spouses programs, and reemployment programs. It was revealed that, even when companies had human resources management systems in place to deal with spousal transfers, they were not necessarily thorough in their responses.Workplace transfer programs are offered by companies across the country, implementing course based personnel management systems. Such programs have often been used, but transfers for trailing spouses pose difficulties for the following four reasons. First problem is location. A job location must be found within a territory where the trailing spouse’s company operates, where there must be a job opening, and the more rural area is, the fewer jobs it has. Second problem is job content; as the work may vary according to the workplace locations, one may have to make a choice to opting for the location or for a job in which one has experiences. Third, such programs are part of regular personnel rotations, hence, there is a time lag before starting the new job. The program applicants have to deal with issues involved in the job transfer while waiting for the company’s decision on whether the relocation is accepted. Fourth, such programs do not envision reuse within a short period of time. Though reuse is formally possible, it is not culturally accepted.Administrative leave for trailing spouses programs is mainly set to prevent women in career track positions from resigning. In many companies, such programs are limited to those whose spouses have been transferred overseas. This non-statutory leave involves the following three issues. First, such programs contain several restrictions: approval authority lies with the company and the total of each leave period must be within the fixed limit. These restrictions make it impossible for such programs to meet individual needs. Second, administrative leave causes a gap in one’s career. Because such programs are not statutory, the companies do not offer assistance in reentering the work force, and it is not even considered. Third, cases of domestic transfers are basically ineligible. In addition, there are no plans to expand such eligibility.Reemployment programs are implemented as a form of mid-career hiring, so they are easy to introduce, and many companies have done so. Reemployment after being out of the work force is not the continuation of employment but a way to restart employment, which involves the following three issues. First, taking advantage of these programs is difficult unless the employee’s spouse’s transfer has been stopped, because there is a limit to the number of years that one may be out of the work force. Second, similar to administrative leave for trailing spouses programs, there would be a gap in one’s employment history, so getting back into one’s career is difficult. Third, reemployment possibilities are determined by companies’ needs since such programs can be customized for responding the business climate.Job transfers affect not only the transferred ones but also their spouses’ companies. Companies that transfer employees are on both the giving and receiving ends of this impact. However, the fact is that companies have little awareness of it. Even if they introduce human resources management systems for spousal transfers, they are unable to carry them out well. When a company transfers an employee, it is crucial to consider how to support the employee, which includes provision of an adequate explanation beforehand, coordination between the company and the employee, and achievement of a mutual agreement.
著者
藤井 修平
出版者
日本宗教学会
雑誌
宗教研究 (ISSN:03873293)
巻号頁・発行日
vol.90, no.1, pp.75-97, 2016

<p>本論文は、宗教進化論を特定の時間的枠組みの下に宗教事象の配列および秩序づけを行うものと定義し、その十九世紀から二十世紀に至る系譜を記述することを目的とする。従来の学説史では人類の文化が呪術から宗教へと発展し、科学へと至るという言説のみが進化論として理解されていたが、宗教進化論は時代を通してさまざまな形態をとっており、またそれは生物学的進化論との緊張により発展してきたという側面も見られる。</p><p> 本論文ではまず「進化」の概念を整理した上で、宗教進化論の再定義を行う。宗教進化論は、単一の進歩の尺度を設定し、時代を経るごとにその尺度とされる要素が増大するとみなすことによって、歴史上の宗教を特徴づけ、配列する言説として定義される。そしてそのような進化論的枠組みを有する理論として、コント、スペンサーによる枠組みの成立から、新進化論学派とパーソンズ、ベラーによる進化論の復興、そして現代の宗教進化論に至るまでの歴史を描写する。</p>
著者
石井 敬子
出版者
日本感情心理学会
雑誌
感情心理学研究 (ISSN:18828817)
巻号頁・発行日
vol.20, no.1, pp.19-23, 2012

The mutual constitution of culture and the mind has been found in various fundamental psychological processes. One important research question is to expand the previous findings and examine neural processes that may vary across cultural groups. Moreover, a growing body of research shows that a person's psychological tendency may emerge as a result of an interaction between genetic and environmental factors and that certain genes may be associated with greater plasticity or susceptibility to the environment. If these environmental factors include cultural ideas and practices, an interaction between genetic and cultural factors may shape the individual's psychological and neural processes. Here, this review will highlight some emerging studies that explore whether and to what extent genes are linked to culture and the mind and discuss the implications.
著者
中村 本然
出版者
智山勧学会
雑誌
智山学報 (ISSN:02865661)
巻号頁・発行日
vol.67, pp.96-137, 2018 (Released:2019-03-30)
参考文献数
110

『釈摩訶衍論』は修行論として、止観の法門を重視する論を展開する。修行者にとって魔事は克服すべき課題であり、『釈摩訶衍論』の論主にとっても念頭から離れることはなかった。「広釈魔事対治門」では、魔・外道・鬼・神の四種の仮人について詳細な考証が施されている。中でも修行者を迷わせる外道に多方面からの検討がみられる。『大乗起信論』の注釈書である元暁の『起信論疏』には、諸魔を天魔、鬼を堆愓鬼、神を精媚神とする。法蔵の『大乗起信論義記』は元暁の解釈を引き継ぐ姿勢を窺わせる。報告では、止観の修行に注目した『釈摩訶衍論』の論主の趣旨に迫ることにした。