著者
加藤 完 高橋 誠 吉川 清志
出版者
公益社団法人 日本地震学会
雑誌
地震 第2輯 (ISSN:00371114)
巻号頁・発行日
vol.39, no.1, pp.47-55, 1986-03-25 (Released:2010-11-17)
参考文献数
16
被引用文献数
2

Weekly monitoring of radon concentration in soil gas in some active fault areas has been carried out using cellulose nitrate film as a part of earthquake prediction research. As the results of observation, we found increase of track density (tracks/cm2day) along the Median Tectonic Line (distance 100km) and the Matsushiro fault (_??_100km) since summer of 1982 and along the Ateta fault (_??_25km) since summer of 1983. We considered it as a precursor of the Western Nagano Prefecture Earthquake, 1984, by the reason that this increase just fit with the empirical formulas which relate the distance and apperance time of the precursory anomaly against the magnitude of an earthquake.At the same time, we found an annual variation of track density higher in summer and lower in winter. Supposing this annual variation being due to the seasonal variation of soil temperature, using uranium ore as source of random. As the result of experiment, it was clarified that track density increased with increased exposure temperature.
著者
船津 康裕 神長 憲宏 浦上 尚之 千野 晶子 岩重 元栄 遠藤 豊 藤田 力也
出版者
昭和大学学士会
雑誌
昭和医学会雑誌 (ISSN:00374342)
巻号頁・発行日
vol.61, no.1, pp.84-93, 2001-02-28 (Released:2010-09-09)
参考文献数
24

クローン病の治療方針を決める指標として大腸内視鏡所見が応用可能かどうかについて臨床検討を行った.対象は成分栄養療法を行った, 大腸及び終末回腸に病変を有する23例のクローン病症例 (大腸型9例, 小腸大腸型10例, 小腸型4例) である.目的はクローン病の活動性の指標であるIOIBD, CDAI, 血沈 (ESR) , CRPと, 胃潰瘍病期分類に準じた内視鏡的潰瘍stage分類の比較を行い, 内視鏡検査の有用性を検討した.IOIBD, CDAIおよびCRP, ESRの緩解までの期間と, 内視鏡所見で潰瘍が治癒するまでの期間とを比較すると, 緩解が得られた時点での内視鏡像は治癒過程期16例 (H1stage1例, H1H2stage1例, H2stage2例, H2S1stage12例) , 瘢痕期7例 (S1stage4例, SIS2stage2例, S2stage1例) であり, 全ての潰瘍が瘢痕化 (S2stage) するには, さらに数ヶ月の期間を要した.次に緩解持続期間と緩解時の内視鏡stageの関連を検討した.S2stage (23.6±31.0月: 11例) まで改善した症例の方が, S1S2stage (7.6±6.3ヶ月: 7例) , S1stage (3.6±1.7ヶ月: 5例) までの症例に比べ有意に緩解持続期間が長かった (p<0.05) .また臨床的に緩解期と診断されていても, 内視鏡的にはすでに潰瘍が出現している症例が多かった.以上のことから, クローン病では長期間の緩解を持続させるためにはS2 stageまで治療を継続させることが重要であり, それにはより長い治療期間が必要である.また再燃に先行して内視鏡的増悪が確認できた症例が多く, 他の指標に比べ内視鏡検査は再燃の早期発見に有用であった.大腸内視鏡検査でクローン病の腸管病変を評価することは, 治療方針を決定するうえで非常に有用であった.
著者
Toshihiro TSUKUI Masahiro SAKAGUCHI Keigo KURATA Sadatoshi MAEDA Keitaro OHMORI Kenichi MASUDA Hajime TSUJIMOTO Shigehiro IWABUCHI
出版者
公益社団法人 日本獣医学会
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
vol.74, no.7, pp.851-856, 2012 (Released:2012-08-04)
参考文献数
30
被引用文献数
3 6

To detect allergen-specific IgE in dogs with allergic diseases, we developed a recombinant canine high affinity IgE receptor α chain (FcεRIα)-based IgE detection system. Using the recombinant protein of canine FcεRIα expressed by an Escherichia coli expression system, we could detect house dust mite (Dermatophagoides farinae) allergen-specific IgE in sera from dogs naturally and experimentally sensitized to this allergen with ELISA and western blotting. The IgE binding activity of recombinant canine FcεRIα on ELISA was impaired by heat treatment of these sera. The specificity of this recombinant canine FcεRIα-based IgE detection system was confirmed by inhibition assays with canine IgE. The recombinant canine FcεRIα-based IgE detection system established in this study offers an alternative tool to measure allergen-specific IgE in dogs.
著者
林 農 加藤 優 田川 公太朗 原 豊
出版者
一般社団法人 日本機械学会
雑誌
日本機械学会論文集 B編 (ISSN:03875016)
巻号頁・発行日
vol.74, no.740, pp.841-849, 2008-04-25 (Released:2011-08-16)
参考文献数
11
被引用文献数
1

In recent years, the wind turbines have been installed actively and the suitable sites of wind farm have been decreased on land. On the other hand, a lot of wind energy resources are latent and it is expected that wind power will be installed in the future on the sea. This study aims to establish a measurement method of wind characteristics using a small ship for decision of suitable site for offshore wind power. We constructed the wind measurement system, which is composed of an ultrasonic anemometer, a differential GPS (DGPS) and an inertial measurement unit. The system was installed to a small ship and wind characteristics at 10 m height above the sea surface were measured by an ultrasonic anemometer on the Sea of Japan close to Tottori prefecture. Raw data of the wind velocity obtained in the proposed method includes the error caused by the pitching, rolling and yawing of the ship. In this study, the raw data of wind velocity was corrected by the data of the DGPS and the inertial measurement unit. Conclusively, the raw wind velocity contaminated by the oscillation and cruising of the ship was corrected and the wind velocity maps were obtained.
著者
伍 培明 川村 宏 木村 富士男
出版者
社団法人 日本リモートセンシング学会
雑誌
日本リモートセンシング学会誌 (ISSN:02897911)
巻号頁・発行日
vol.17, no.5, pp.518-523, 1997-12-30 (Released:2009-05-29)
参考文献数
3

Winds are the critical factor in determining regional weather patterns and climate. In winter, the winds over the Sea of Japan have great effect on the weather of Japan islands. In this paper, wind distribution over the Sea of Japan is analyzed by using wind data observed by NASA Scatterometer (NSCAT) aboard Japan's Advanced Earth Observing Satellite (ADEOS, Midori).Synoptic views of the wind field over the Sea of Japan show remarkable evidence of a land topography effect causing a convergence of the surface wind field during cold-air outbreaks. The Changbai mountains in the North Korea locates at upstream of outbreak winds, and the wind field is deformed by them over the western part of the Sea of Japan. Strong north winds and northwesterly winds of about 15-20 m/s are observed off Vladivostok and off the Korea Peninsula, respectively, and they converge while blowing over the Sea of Japan. A wind shadow, where the wind speed is less than about 9 m/s, is seen in the downwind of the mountains, extending more than 200 km. Numerical experiments using a three-dimensional local circulation model were performed to investigate the formation mechanisms of the outbreak-wind deformation. The results show that the simulated winds agree well with the NSCAT observed winds.
著者
目野 幹雄
出版者
公益社団法人 土木学会
雑誌
海岸工学講演会講演集 (ISSN:04194918)
巻号頁・発行日
vol.12, pp.56-63, 1965-11-15 (Released:2010-06-04)
参考文献数
35

前回の報告ではMiles-Phillipsの風波発生理論とPhillipsの平衡領域のスペクトル理論をもとにして, 風波特性の解明を試みた。この論文では, さらに, 風と波との相互作用を支配する原理として “エネルギー仮説” を提出し, これから導かれる一連の理論的結果として, fetch graph, スペクトル最大の周波数, 海面粗度係数などを求め, また風と波との間のエネルギー授受の力学関係をも示すことができた (なお, 文中前の2報告をそれぞれ論文I, IIとして引用する)。
著者
近藤 純正
出版者
一般社団法人 日本風工学会
雑誌
日本風工学会誌 (ISSN:09121935)
巻号頁・発行日
vol.1985, no.23, pp.23-35, 1985-03-31 (Released:2010-09-28)
参考文献数
10

A large number of forest fires were caused by unusual strong dry winds over northeastern Japan on 27 April 1983. The total area of devastated forest by these fires amounted to about 9, 000 hectare. The present paper explains this particular weather phenomenon and shows a method to predict the local wind speed under strong wind conditions.
著者
Tomoko IWANAGA Naoki MIURA Noriaki MIYOSHI Yasuyuki ENDO Yasuyuki MOMOI
出版者
公益社団法人 日本獣医学会
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
vol.74, no.7, pp.909-912, 2012 (Released:2012-08-04)
参考文献数
13
被引用文献数
6

A cat was presented with severe progressive anemia despite marked erythroblastosis. The cat was negative for feline leukemia virus antigen and feline immunodeficiency virus antibody. Bone marrow cytology revealed an excess of erythroid cells with a predominance of prorubricytes and basophilic rubricytes. No response to immunosuppressive therapy was obtained, and a tentative diagnosis of myelodysplastic syndrome was made. The cat showed a partial response to low-dose cytarabine (20 mg/m2 subcutaneously q24) but died 51 days after the 1st admission. Histopathological examination revealed fibrosis in the bone marrow and marked infiltration of erythroid cells into other organs.
著者
Daiki MURATA Naoki MIURA Tomoko IWANAGA Satoshi TOKUNAGA Noriaki MIYOSHI Yoshiaki KITANO Yasuyuki MOMOI Makoto FUJIKI
出版者
公益社団法人 日本獣医学会
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
vol.74, no.7, pp.913-915, 2012 (Released:2012-08-04)
参考文献数
8
被引用文献数
1 4

A 12-year-old neutered male shih tzu developed progressive pelvic limb paraparesis. Computed tomography showed a radiolucent mass lesion in the spinal canal at the left side of the 11th thoracic vertebra. The mass was not enhanced by intravenous contrast medium injection. It was hyperintense on both T1- and T2-weighted magnetic resonance images. The signal intensity of the mass was decreased with a fat suppression technique, indicating a fatty origin. After removal of the mass via T11–T12 hemilaminectomy, chronic panniculitis was confirmed by histopathological examination. This case demonstrates the utility of computed tomography and magnetic resonance imaging for the diagnosis of spinal canal pyogranulomatous inflammation.
著者
Byung-Jae KANG Hak-Hyun RYU Sung-Su PARK Yongsun KIM Heung-Myong WOO Wan Hee KIM Oh-Kyeong KWEON
出版者
公益社団法人 日本獣医学会
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
vol.74, no.7, pp.827-836, 2012 (Released:2012-08-04)
参考文献数
35
被引用文献数
8 24

Adipose tissue-derived mesenchymal stem cells (Ad-MSCs) are a promising source of cells for bone tissue engineering. Matrigel is a basement membrane extract containing multiple extracellular components. This mixture may promote the osteogenic differentiation of MSCs and provide a more appropriate microenvironment for transplanted cells. Here, we investigated the effect of Matrigel on the osteogenic potential of Ad-MSCs. Canine Ad-MSCs were cultured in 2D and 3D matrices and implanted into subcutaneous pouches of dogs either with or without Matrigel. Culture mineralization, cell adhesion efficiency, cell proliferation, osteoid matrix production and alkaline phosphatase (ALP) and tartrate-resistant acid phosphatase activities were quantified and compared. Ad-MSCs grown in 2D cultures with Matrigel showed higher levels of calcium deposition and ALP activity than those grown in the absence of Matrigel under osteogenic conditions. In 3D cultures, the cells cultivated with Matrigel showed greater attachment, proliferation and osteogenic differentiation than those grown without Matrigel. In vivo, Ad-MSCs implanted with Matrigel showed higher osteogenic potential than those without Matrigel. In conclusion, these data suggest that the use of Matrigel can increase the osteogenic potential of canine Ad-MSCs.
著者
Ai WATABE Kiwamu HANAZONO Takahiro KOMATSU Dah-Renn FU Yoshifumi ENDO Tsuyoshi KADOSAWA
出版者
公益社団法人 日本獣医学会
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
vol.74, no.7, pp.937-943, 2012 (Released:2012-08-04)
参考文献数
22
被引用文献数
2 4

To evaluate the relationship among immune status and increased morbidity and mortality, peripheral blood lymphocytes (CD3+, CD4+, CD8+ and CD21+ cells) from 32 healthy dogs over 8 years of age were analyzed. Twenty-five of the 32 dogs were followed-up for 3 years after the analysis; and 14 dogs were found to be diseased, and nine dogs died. There was no notable difference between the ages of the dogs that died compared with the ones that survived. The relative percentage of CD4+ and the CD4+:CD8+ ratio decreased notably in dogs falling ill compared with healthy dogs. The relative percentage of CD3+ lymphocytes showed a notable decrease in dogs that died within 3 years in comparison with dogs that survived. In a discriminant analysis of morbidity and mortality, most patients were correctly classified as diseased or not and surviving or dead, respectively. These results indicate that the immunophenotypes of peripheral blood lymphocytes in older dogs offer promise as parameters for evaluating mortality and morbidity.
著者
Ryota NOMURA Mitsuyuki SHIRAI Yukio KATO Masaru MURAKAMI Kazuhiko NAKANO Norihiko HIRAI Tetsuya MIZUSAWA Shuhei NAKA Yoshie YAMASAKI Michiyo MATSUMOTO-NAKANO Takashi OOSHIMA Fumitoshi ASAI
出版者
JAPANESE SOCIETY OF VETERINARY SCIENCE
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
vol.74, no.7, pp.885-891, 2012 (Released:2012-08-04)
参考文献数
18
被引用文献数
8 16

Porphyromonas gulae, a gram-negative black-pigmented anaerobe, is a pathogen for periodontitis in dogs. An approximately 41-kDa fimbrial subunit protein (FimA) encoded by fimA is regarded as associated with periodontitis. In the present study, the fimA genes of 17 P. gulae strains were sequenced, and classified into two major types. The generation of phylogenetic trees based on the deduced amino acid sequence of FimA of P. gulae strains along with sequences from several strains of Porphyromonas gingivalis, a major cause of human periodontitis, revealed that the two types of FimA (types A and B) of P. gulae were similar to type I FimA and types II and III FimA of P. gingivalis, respectively. A PCR system for classification was established based on differences in the nucleotide sequences of the fimA genes. Analysis of 115 P. gulae-positive oral swab specimens from dogs revealed that 42.6%, 22.6%, and 26.1% of them contained type A, type B, and both type A and B fimA genes, respectively. Experiments with a mouse abscess model demonstrated that the strains with type B fimA caused significantly greater systemic inflammation than those with type A. These results suggest that the FimA proteins of P. gulae are diverse with two major types and that strains with type B fimA could be more virulent.
著者
桑野 玲子 佐藤 真理
出版者
東京大学生産技術研究所
雑誌
生産研究 (ISSN:0037105X)
巻号頁・発行日
vol.61, no.4, pp.673-677, 2009 (Released:2009-08-05)
参考文献数
8

近年都市部で頻発している道路陥没は, 多くの場合老朽埋設管の破損部等から土砂が流出することに起因し, 社会的損失が大きいにもかかわらず, 対症療法的な対策が中心となっているのが現状である.また, 道路や住宅造成地等で起こる比較的大規模な陥没にははっきりした原因が特定できない場合もあり, 埋設構造物周辺の埋戻し不良や地下の水みちに沿った土砂流出等が長年にわたって地盤内ゆるみを助長し陥没に至ったと推定される.舗装下の地表近傍で顕著な空洞が存在するような陥没寸前の状態においては, 現状のレーダー探査技術により比較的高い確度で探知可能であるが, 空洞が深層部にある場合, 空洞・ゆるみの境界が不明瞭な場合, 輻輳した地下埋設物と空洞・ゆるみ部が渾然としている場合などは, 探知技術の限界により問題箇所の検出が困難である.本研究では, 地盤陥没を未然に防止するための探知手法を提案するために, 地盤内空洞・ゆるみの形成過程を明らかにし空洞・ゆるみのパターンを類型化すること, さらに陥没に至る“危険な”ゆるみを抽出することを目指している.まだ本取組みは継続中であるがその概要を紹介する.[本要旨はPDFには含まれない]
著者
宇陀 則彦
出版者
一般社団法人 情報科学技術協会
雑誌
情報プロフェッショナルシンポジウム予稿集 第4回情報プロフェッショナルシンポジウム
巻号頁・発行日
pp.131-134, 2007 (Released:2007-10-10)
参考文献数
2

筑波大学附属図書館では、2006年3月に電子図書館システムの更新をおこなった。新システムのメインコンセプトの一つはポータルであったが、期待していたほどの効果はなかった。その原因を探るため、利用者への聞き取り調査を行ったところ、ポータルデザインが利用者の予想イメージと一致しないこと、利用者は必ずしもポータルを出発点としないこと、情報資源へアクセスする際の道筋も多様であることなどが原因であることが明らかになった。これらのことから、図書館ポータルをデザインする際には、利用者のシステムに対するメンタルモデルを予測し、複数のアクセスパスを適切に設定することが重要であることを導いた。さらに、ベンダーごとの仕様の違いがポータル構築の障害になることを指摘した。
著者
梶原 誠司 佐藤 康夫
出版者
一般社団法人 電子情報通信学会
雑誌
電子情報通信学会 基礎・境界ソサイエティ Fundamentals Review (ISSN:18820875)
巻号頁・発行日
vol.1, no.3, pp.3_71-3_77, 2008-01-01 (Released:2011-03-01)
参考文献数
21
被引用文献数
1

半導体製造プロセスの微細化やSoC(System-on-a-Chip)の高速化に伴い,遅延故障のテストの重要性が高まっている.論理回路の遅延故障のテストには,高精度な測定を可能にするDFT(Design for Testability)やテストパターン印加の仕組み,フォールスパスを考慮し故障の伝搬経路長を考慮したATPG(Automatic Test Pattern Generation:自動テストパターン生成),SoCのテストでは,高速クロック生成,複数クロックドメインへの対応等の総合的アプローチが必要である.本論文では,基本となる遅延故障のテスト手法を解説する.
著者
加藤 文男
出版者
日本魚類学会
雑誌
魚類学雑誌 (ISSN:00215090)
巻号頁・発行日
vol.22, no.3, pp.183-185, 1975-12-29 (Released:2011-02-23)
参考文献数
7

Four large specimens of freshwater salmons, 365 to 567 mm in total length, were collected in Kuzuryu Dam, and in the upper streams of Takinami River and Kuroko River, Fukui Prefecture.These specimens are two or three years old, and have higher depth of body than that of the salmonid fish“Biwamasu” (lacustrine form) in Lake Biwa, and the crimson spots on both sides of body.These spots are similar to those of the smaller“Amago”, but differ from those of the“Biwamasu”.The number of transverse scales of the present mateial is more than those of the“Biwamasu”.From the comparison described above and the fact that the“Amago”of Oncorhynchus rhodurus Jordan and McGregor was introduced artificially into the upper streams of Kuzuryu River, Takinami River and Kuroko River before, the author identified the present material as the“Amago”O.rhodurus which inhabits the rivers.