著者
篠田 浩一 井上 中順 岩野 公司 宇都 有昭
出版者
東京工業大学
雑誌
基盤研究(B)
巻号頁・発行日
2019-04-01

音声に関する音声認識、音声合成、話者認識などの様々なタスクを担当するエージェントが互いに競争・協調・調整しながら個々のタスクを学習する、マルチエージェントによる深層学習基盤を構築する。個々のタスクに関わる音声因子の間の含有・排他・共有などの関係を用いて音声データを因子分解することにより、個々のタスクの性能を高める。マルチタスク学習に比べ、少量・非均一のデータでより高い性能を得ることを目標とする。
著者
島村 忠勝 胡 志青 大久保 幸枝 趙 維華 柳川 容子 山口 晃史
出版者
昭和大学
雑誌
基盤研究(B)
巻号頁・発行日
1999

カテキンの抗微生物活性のメカニズムおよびカテキンの抗微生物薬との併用効果について研究を行った。1.エピガロカテキンガレート(EGCg)は細菌細胞膜や細胞壁傷害作用および細胞壁合成阻害作用を有し、β-ラクタム剤と併用すると、MRSAに対するβ-ラクタム剤の抗菌活性を復活させ、強い相乗効果が発現した。タンパク合成阻害剤、核酸合成阻害剤との併用では相乗効果は見られず、ペプチド系抗生物質では拮抗作用が見られた。この拮抗作用はEGCgとペプチドの結合によると考えられた。また、EGCgはβ-ラクタマーゼ活性を直接阻害することができ、β-ラクタマーゼ産生黄色ブドウ球菌およびMRSAに対して、EGCgとβ-ラクタム剤の併用は相乗効果を発揮した。β-ラクタマーゼが分泌されないグラム陰性桿菌に対して、効果は弱かった。2.ヘリコバクター・ピロリに対しては、EGCg単独で殺菌作用を示した。クラリスロマイシン高度耐性株に対してEGCgとクラリスロマイシンまたはプロトンポンプ阻害剤を併用すると相加効果が見られた。3.細胞内寄生菌サルモネラに関しては、EGCgはサルモネラ食食マウスマクロファージの細胞内殺菌能を亢進した。EGCg投与マウスのマクロファージはサルモネラ貧食能と細胞内殺菌能がともに増強した。4.HIVに関しては、HIVの細胞への吸着後から宿主細胞遺伝子への挿入までの過程においてEGCgの阻害作用が見られ、逆転写酵素やプロテアーゼの阻害が示唆された。また、EGCgは持続感染細胞からのHIV粒子の産生を抑制した。この抑制効果はリボソームに包埋したEGCgやLPSを併用すると増強した。しかし、このEGCgの効果は単球細胞系で特異的におこり、リンパ球では見られなかった。また、EGCgとAZTを併用すると弱いながら相乗効果が見られた。
著者
馬上 謙一 山本 征生 長尾 敬介 本田 雅健
出版者
日本地球化学会
雑誌
日本地球化学会年会要旨集
巻号頁・発行日
vol.53, pp.154-154, 2006

鉄隕石Gibeon(IVA)のいろいろなフラグメントの希ガス(He、Ne、Ar)同位体組成を測定した。これらの希ガスは宇宙線照射起源であり、地球落下前の鉄隕石の表面付近と中心部分の3Heのガス量の分布が6桁ほども差があることがわかった。このような鉄隕石のデータはこれまで報告されたことがない。鉄隕石の希ガス分析は、石質隕石の分析に較べて様々な実験的困難が伴う。本講演では、特に宇宙線照射起源希ガス濃度が低い中心部の試料の測定方法について詳細に述べる。
著者
Romar Correa
出版者
The Keynes Society Japan
雑誌
The Review of Keynesian Studies (ISSN:24356581)
巻号頁・発行日
vol.2, pp.175-190, 2020 (Released:2021-04-24)
参考文献数
17

We explore the connections between the Treatise on Money by JM Keynes and the monetary macroeconomics of Bernard Schmitt. The link is shown to be the role of the bank. Secondly, we define a Keynes-Schmitt equilibrium without market clearing. We derive a comparative static result: an increase in the money wage raises the level of output. Finally, we provide a rendition of Keynes’ General Theory plan to determine the level of output as a whole.
著者
Atsushi Naito
出版者
The Keynes Society Japan
雑誌
The Review of Keynesian Studies (ISSN:24356581)
巻号頁・発行日
vol.2, pp.122-147, 2020 (Released:2021-04-24)
参考文献数
40

This paper focuses on the unit of account function of money that is emphasized by Keynes in his book A Treatise on Money (1930) and recently in post-Keynesian endogenous money theory and modern Chartalism, or in other words Modern Monetary Theory. These theories consider the nominality of money as an important characteristic because the unit of account and the corresponding money as a substance could be anything, and this aspect highlights the nominal nature of money; however, although these theories are closely associated, they are different. The three objectives of this paper are to investigate the nominality of money common to both the theories, examine the relationship and differences between the two theories with a focus on Chartalism, and elucidate the significance and policy implications of Chartalism.
著者
Willi Semmler Alexander Haider Andreas Lichtenberger
出版者
The Keynes Society Japan
雑誌
The Review of Keynesian Studies (ISSN:24356581)
巻号頁・発行日
vol.2, pp.78-121, 2020 (Released:2021-04-24)
参考文献数
70

The multiplier effect of fiscal spending has long been an object of study. The great recession of 2007-9 and the US fiscal stimulus program revived empirical studies on the multiplier, showing the wide range its value can take. This paper explores the effects of the fiscal multiplier in the context of a Keynesian business cycle theory, emphasizing the regime dependence of the multiplier. It is, as Keynes, Minsky and Kindleberger suggest, the state of the business cycle, the flow of credits, financial fragility and financial stress that are of importance for the size of the fiscal multiplier. But the multiplier effect is also essentially dependent on the monetary policy stance, which affects the financial stress, the interest rate and risk premia. Thus, one can observe that the size of multiplier is not only dependent on the state of the business cycle, financial fragility and financial stress, but also subject to the extent of fiscal action as well as the accompanying type of monetary policy. Lastly, human behavior driven by uncertainties about the future, as holds for the recent Pandemic Recession, can also significantly affect the fiscal multiplier.
著者
Maria Cristina Marcuzzo
出版者
The Keynes Society Japan
雑誌
The Review of Keynesian Studies (ISSN:24356581)
巻号頁・発行日
vol.2, pp.1-21, 2020 (Released:2021-04-24)
参考文献数
30

Over twenty-five years have been wasted praising the efficiency of free markets and running econometric tests to prove that economic policies are either ineffectual or even irrelevant, reflecting an academic scene still dominated by the macroeconomics of anti- or pre-Keynesian inspiration that took hold between the 1970s and 1980s. Increasingly sophisticated models were developed to support the argument that government intervention to stabilize the economy was not only unnecessary but actually harmful. The idea of the centrality of changes in aggregate current income (both with positive and negative signs) and its distribution in fuelling or dampening economic growth were forgotten. It is time that we brought Keynes’s ideas back.
著者
Robert W. Dimand
出版者
The Keynes Society Japan
雑誌
The Review of Keynesian Studies (ISSN:24356581)
巻号頁・発行日
vol.2, pp.22-45, 2020 (Released:2021-04-24)
参考文献数
72

The Cowles Foundation for Research in Economics was, in the first decades after its establishment at Yale in 1955, closely associated with the Keynesian economics of James Tobin and his “Yale school” approach to monetary economics. Its predecessor, the Cowles Commission, was not at first Keynesian: a few papers on Keynes were presented at the Cowles summer conferences in Colorado in the late 1930s but Harold Davis’s Analysis of Economic Time Series (Cowles Monograph No. 7, 1941) dismissed Keynes’s General Theory in a footnote, focusing instead on theories of fluctuations as truly periodic cycles, including Jevons on sunspots. But in the 1940s Oskar Lange and Jacob Marschak took the lead at the Cowles Commission in promoting a distinctive formulation of Keynesianism: Keynesian economics as a small general equilibrium system of simultaneous equations suitable for guiding aggregate demand management. Key works were Lange’s 1938 articles and 1944 Cowles monograph on Price Flexibility and Employment, a joint paper that Lange and Marschak submitted to the Economic Journal responding to Keynes’s critique of Tinbergen, and Marschak’s Chicago lectures, published as Income, Employment and the Price Level (1951), as well as articles by Marschak’s doctoral students Franco Modigliani (1944) and Don Patinkin (1947 to 1949). This approach contrasted with the emphasis on fundamental uncertainty in Keynes’s 1937 QJE reply to reviews of his General Theory, but not with the system of four simultaneous equations in the concluding lecture of Keynes’s Michaelmas 1933 lectures (an approach that Keynes did not carry over into the General Theory). Lawrence Klein, author of The Keynesian Revolution (1946) and a 1950 Cowles monograph on Economic Fluctuations in the United States, was at Cowles 1944-47. This view of the Cowles Commission, after Marschak became research director in January 1943, as Keynesian but in a distinctive way differs from the interpretation by Philip Mirowski, “The Cowles Commission as an Anti-Keynesian Stronghold 1943-54” (2012).
著者
Rod O’Donnell
出版者
The Keynes Society Japan
雑誌
The Review of Keynesian Studies (ISSN:24356581)
巻号頁・発行日
vol.2, pp.46-77, 2020 (Released:2021-04-24)
参考文献数
26

Keynes and Paley are two names rarely conjoined in the literature of either figure. Keynes, however, made significant references to Paley in four of his essays. Most commentators treat these as historical ephemera, but closer investigations reveal that they illuminate key aspects of his thought. These include whether Paley or Malthus was the first Cambridge economist, methodological issues concerning the nature of economic theorising and how best to disseminate economic thought, and relationships between scientific and religious explanations. They also serve the useful task of clarifying and correcting certain errors in Keynes’s essays due to exaggeration or inaccuracy. In these contexts, Keynes’s remarks on Paley repay investigation.
著者
Xi Ding Yang Zhao Chun-Ying Zhu Li-Ping Wu Yue Wang Zhao-Yi Peng Cuomu Deji Feng-Yi Zhao Bing-Yin Shi
出版者
The Japan Endocrine Society
雑誌
Endocrine Journal (ISSN:09188959)
巻号頁・発行日
pp.EJ20-0796, (Released:2021-04-21)
被引用文献数
19

The association between subclinical hypothyroidism (SCH) and metabolic syndrome (MetS) has been widely discussed. This study aimed to conduct an update and comprehensive meta-analysis to reveal the risk of MetS and its components in SCH. PubMed, Embase and ISI Web of Knowledge were searched to identify relevant studies through February 20th, 2020. Review Manager 5.3 and Stata 14.0 were used to conduct the meta-analysis. Both fixed-effects and random-effects models were used. In total, 18 articles (19 studies) incorporating 79,727 participants were included. The pooled OR for MetS comparing subjects with SCH with euthyroid subjects was 1.28 (95% CI: 1.19 to 1.39, p = 0.04, I2 = 40%). Subgroup analysis results showed significant associations of SCH and MetS in the adult subgroup (OR = 1.28, 95% CI: 1.18–1.40), Asian population subgroup (OR = 1.30, 95% CI: 1.19–1.42) and cross-sectional study design subgroup (OR = 1.31, 95% CI: 1.16–1.47). Significant associations of SCH and MetS also existed in all MetS definition criteria subgroups except the Chinese Diabetes Society (CDS) subgroup. SCH was correlated with MetS and was not affected by the subgroup analysis stratified by the proportion of females in the total population, the TSH cutoff value in SCH diagnostic criteria, or the adjustment for confounding factors. SCH was identified to be associated with an increased risk of obesity, hypertension, high triglyceride (TG) levels and low high-density lipoprotein cholesterol (HDL-C) levels. In conclusion, SCH is significantly associated with an increased risk of MetS and four out of five components of MetS.

1 0 0 0 OA 暗射地球図解

著者
吉田伝次 著
出版者
日新堂
巻号頁・発行日
1876

1 0 0 0 OA 暗射図符号解

著者
久保譲次 編
出版者
文部省
巻号頁・発行日
1876