著者
Vincenzo Catanese Matteo Alberto Pegorer Daniele Bissacco Sara Di Gregorio Raffaello Dallatana Piergiorgio Settembrini
出版者
Annals of Vascular Diseases 編集委員会
雑誌
Annals of Vascular Diseases (ISSN:1881641X)
巻号頁・発行日
vol.7, no.3, pp.347-349, 2014 (Released:2014-09-25)
参考文献数
14
被引用文献数
2 5

Subclavian Artery Dissection (SAD) is a rare condition, generally due to arterial catheterization, blunt trauma or connective tissue disease. Spontaneous or minimally traumatic cases have also been reported. Clinical manifestations are usually chest and/or back pain, pulse loss and paresthesia, whereas nausea, dizziness and vomiting are present in case of involvement of the vertebral artery. We report an unusual case of a young woman presenting isolated left SAD after traffic accident, minimally symptomatic, and treated with medical therapy alone. A conservative management and a closed follow-up appear to be a safe approach in patients affected by uncomplicated SAD without other comorbidities.
著者
國弘 幸伸 中山 明峰
出版者
一般社団法人 日本めまい平衡医学会
雑誌
Equilibrium Research (ISSN:03855716)
巻号頁・発行日
vol.70, no.6, pp.465-472, 2011 (Released:2012-02-01)
参考文献数
14

Along with Epley's canalith repositioning maneuver, the Semont maneuver is also recognized as an effective physical therapy for benign paroxysmal positional vertigo. However, the details of this maneuver are not well known, presumably because of the obscurity of the original description by Semont et al. In Japan, the “Semont liberatory maneuver,” as described by Brandt, is accepted as the “original” Semont maneuver. However, the two maneuvers are not identical. The aim of this paper was to reproduce the original procedure of Semont's as presented by A. Semont himself at the 10th Nagoya Otorhinolaryngological Forum held in Nagoya, Japan, in 2006. This lecture clarified some obscure points in the original paper; however, the procedure described at the forum was not a detailed reproduction of the original Semont maneuver, but was somewhat more complicated. Also of note, Semont decisively denied the cupulolithiasis theory and explained the usefulness of his maneuver according to the canalolithiasis theory.
著者
Masahiro Haramoto Homare Yamanaka Hiroyasu Hosokawa Hiroshi Sano Shinsuke Sano Hiroshi Otani
出版者
日本農薬学会
雑誌
Journal of Pesticide Science (ISSN:1348589X)
巻号頁・発行日
vol.31, no.2, pp.116-122, 2006 (Released:2006-05-25)
参考文献数
10
被引用文献数
1 11

The control efficacy of a novel fungicide, cyflufenamid, (Z)-N-[α-(cyclopropylmethoxyimino)-2,3-difluoro-6-(trifluoromethyl) benzyl]-2-phenylacetamide was studied. In field trials, a low dosage (25 ppm) of cyflufenamid (10%WG) showed excellent efficacy in almost all plants against powdery mildew caused by various pathogens in agricultural production. Cyflufenamid also had high efficacy against brown rot in stone fruits caused by Monilinia fructicola. The fungicidal properties of cyflufenamid were investigated to elucidate the high performance of the compound in the field. Pot tests against cucumber powdery mildew indicated that cyflufenamid has excellent preventive, curative, long residual, translaminar and vapor phase activities at low concentrations. © Pesticide Science Society of Japan
著者
加藤 貴彦 松尾 佳奈 黒田 庄一郎 盧 渓 小田 政子 大場 隆
出版者
日本衛生学会
雑誌
日本衛生学雑誌 (ISSN:00215082)
巻号頁・発行日
vol.69, no.3, pp.211-214, 2014 (Released:2014-09-24)
参考文献数
3

In a long-term large cohort study, we introduced an electronic money system for remuneration of research participants. In comparison with the delivery of cash vouchers, the operation and mailing cost, and the processing time were significantly reduced. The workers were also able to save the time and effort they spent on the inventory management of cash vouchers. In addition, risk management was improved, as demonstrated by the reduction of complaints and associated problems such as nonarrival or content differences of cash vouchers. This is because only card points as additional money need to be added once the electronic money card has been distributed to the recipients. Furthermore, the psychological stress of workers associated with inventory management and ensuring cash voucher enclosure was also reduced.
著者
Shuso Takeda Kentaro Yaji Kenji Matsumoto Toshiaki Amamoto Mitsuru Shindo Hironori Aramaki
出版者
公益社団法人日本薬学会
雑誌
Biological and Pharmaceutical Bulletin (ISSN:09186158)
巻号頁・発行日
vol.37, no.2, pp.331-334, 2014-02-01 (Released:2014-02-01)
参考文献数
13
被引用文献数
1 4

Few studies have examined xanthocidin, a biotic isolated from Streptomyces xanthocidicus in 1966, because its supply is limited. Based on its chemical structure, xanthocidin has the potential to become a lead compound in the production of agrochemicals and anti-cancer drugs; however, it is unstable under both basic and acidic conditions. We recently established the total synthesis of xanthocidin using the FeCl3-mediated Nazarov reaction, and obtained two stable derivatives (#1 and #2). The results of the present study demonstrated that these derivatives exhibited the inhibitory activity of topoisomerase IIα, known as a molecular target for cancer chemotherapy, and this was attributed to the respective exo-methylene ketone group without DNA intercalation. The results obtained also suggest that these derivatives may have value as lead compounds in the synthesis of topoisomerase IIα inhibitors.
著者
稲葉 洋平 大久保 忠利 内山 茂久 欅田 尚樹
出版者
日本衛生学会
雑誌
日本衛生学雑誌 (ISSN:00215082)
巻号頁・発行日
vol.69, no.3, pp.205-210, 2014 (Released:2014-09-24)
参考文献数
19
被引用文献数
2 2

Objective: The tobacco tax in Japan was increased in October, 2010. Subsequently, the quantity of sales of domestic cigarette products decreased temporarily. However, smokers could import cigarettes directly through the internet. Because of the high value of the yen and the low price of foreign cigarettes, an individual could import cigarettes easily; however, the contents and emissions from privately imported cigarettes have not been investigated yet. In this study, we carried out a comparative analysis of domestic and privately imported cigarettes. Methods: Privately imported cigarettes from five brands and domestic cigarettes from the brand “Mild Seven” were selected for the study. For the fillers of the cigarettes, the levels of nicotine and tobacco-specific nitrosamines (TSNAs) were determined by methods that are usually used for cigarette products. For the mainstream smoke, the levels of tar, nicotine, carbon monoxide, and TSNAs were also determined by the methods used for cigarettes. Results: The average nicotine and TSNA levels in the fillers of the domestic cigarettes were 15.1±0.19 mg/g and 1,920±85.1 ng/g, respectively. The amounts of nicotine and tar in the mainstream smoke from the privately imported cigarettes were lower than those from the domestic cigarettes. However, the levels of TSNAs in the mainstream smoke from the privately imported cigarettes were higher than those from the domestic cigarettes. Conclusions: The amounts of TSNAs in the fillers of and mainstream smoke from the privately imported cigarettes were higher than those from the domestic cigarettes. Japanese smokers should be careful about consuming privately imported cigarettes because there is a variation in the amount of hazardous constituents in these cigarettes, even when they are from the same brand.
著者
鈴木 彌生子 國分 敦子 絵面 智宏 中山 和美
出版者
社団法人 日本食品科学工学会
雑誌
日本食品科学工学会誌 (ISSN:1341027X)
巻号頁・発行日
vol.60, no.1, pp.1-10, 2013-01-15 (Released:2013-02-28)
参考文献数
30
被引用文献数
2 2 3

本研究では,三陸産(45検体)·鳴門産(64検体)·中国(54検体)·韓国(46検体)において産地の明確な湯通し塩蔵ワカメを浜単位で入手し,炭素·窒素·酸素安定同位体比を用いて,産地判別の可能性を検証した.鳴門産については,炭素·窒素同位体比ともに,個体内変動·季節変動·地域変動が小さく,全般的に値が安定した傾向が見られた.また,鳴門産の窒素同位体比は10.7±1.1‰(平均値±標準偏差)となり,三陸産(1.4±1.9‰)·韓国産(0.5±1.6‰)·中国産(3.0±2.5‰)よりも有意に高い傾向が得られた.一部中国産については,炭素同位体比が低く,窒素同位体比が高くなる傾向が得られた.酸素同位体比は,韓国産が比較的高い値を示したが,日本·中国·韓国の平均値の差は2.1‰となり,地域差は小さかった.炭素·窒素同位体比の結果を用いて,鳴門産とその他(三陸·中国·韓国)の2群について判別分析を行った結果,判別関数を構築した試料について,正答率を計算すると,鳴門産は98.4% (64点中),その他産は99.4% (145点中)となった.交差検証法を用いて判別関数の精度を検証した結果,96.8%の鳴門産が正しく分類された.年変動といった検証が必要であるが,炭素·窒素同位体比によって,鳴門産を判別できる可能性が高いと考えられる.
著者
喜田 聡 内田 周作
出版者
公益社団法人 日本薬理学会
雑誌
日本薬理学雑誌 (ISSN:00155691)
巻号頁・発行日
vol.125, no.1, pp.17-24, 2005 (Released:2005-03-01)
参考文献数
12

情動行動は生命を維持するために生じる動物の本能的行動であり,外的・内的な様々な環境要因を反映して制御されると考えられる.我々は,核内受容体のリガンド結合ドメインをツールとして用いた遺伝子操作マウスの解析過程でヒントを得て,ステロイドホルモンや,ビタミンAの活性本体であるレチノイン酸などをリガンドとする一連の核内受容体群が情動行動制御に関わるのではないかと考え,この作業仮説を検討した.その結果,エストロゲン受容体,あるいは,レチノイン酸受容体のアゴニストを投与すると,マウスの不安行動が亢進すること,また,社会行動に変化が生じ,特に社会優勢度が上昇することが明らかとなった.さらに,野生型のエストロゲン受容体を前脳領域特異的に過剰発現するマウスを作製,解析したところ,過剰発現によってアゴニストを投与した場合とほぼ同様の効果が観察された.以上の点から,エストロゲンやレチノイン酸をリガンドとする核内受容体群が情動行動制御に関わっていること,さらに,生体内で恒常性維持に寄与するホルモンや必須栄養素が情動行動制御に関わる可能性が示唆された.
著者
土田 英俊 篠原 功 神原 周
出版者
公益社団法人 日本化学会
雑誌
工業化学雑誌 (ISSN:00232734)
巻号頁・発行日
vol.66, no.6, pp.824-827, 1963-06-05 (Released:2011-09-02)
参考文献数
6
被引用文献数
3

スチレン- 四塩化炭素系のテロメリ化反応により, 重合度範囲3~400のオリゴスチレンを合成した。反応はAIBNを開始剤とし, 重合温度80および60℃で実施した。[CCl4]/[Styrene] が0.2~50の範囲, 温度80℃ では生成物の分子量は300>Pn>3となり,生成オリゴスチレンは一定の重合度分布を持つ帯電現象の著しい白色の粉末である。両末端の塩素定量値と氷点降下法で測定した平均重合度を比較して,生成物がα,α,α,ω-四塩化物であることを確かめた。氷点降下法による数平均分子量と25℃におけるベンゼン溶液の極限粘度を測定して, 次の関係式を得た。[η]=3.64×10-4M0.64これらの結果から必要とする平均重合度のオリゴスチレンを合成する条件が得られた。
著者
鬼塚 健一郎 星野 敏 橋本 禅 九鬼 康彰
出版者
一般社団法人 環境情報科学センター
雑誌
環境情報科学論文集 Vol.26(第26回環境情報科学学術研究論文発表会)
巻号頁・発行日
pp.137-142, 2012-11-26 (Released:2014-09-20)
参考文献数
8

近年,高速なインターネット環境の整備に伴い,地理的条件が不利な中山間地域においても,ブロードバンドや高速モバイル回線が利用可能になりつつある。同時に,地域コミュニティ形成を目的にSNS を活用する例も増えてきており,農村地域でも地域内外における交流促進や情報発信に大きな役割が期待されるが,ICT の学習機会の提供や効果的な普及手法など,ソフト面での対策が必要とされる。本研究では,農村地域におけるコミュニケーション基盤としてSNS の活用を推進するプロセスにおいて,京都府下 3 地域のキーパーソンに着目し,その役割と効果を明らかにするとともに,他地域に対する提言を行った。
著者
Kohji OHTA Yoshiyuki TANAKA Isao KAWATE Toshio TSUJI
出版者
一般社団法人 日本機械学会
雑誌
Journal of Biomechanical Science and Engineering (ISSN:18809863)
巻号頁・発行日
pp.14-00207, (Released:2014-09-16)
参考文献数
16
被引用文献数
6

Human can realize flexible and skillful movements by controlling his/her musculoskeletal system and the interactive force with environments appropriately. However it still exist many uncertain biological motor characteristics in human movements even for a simple task. This paper aims to analyze and evaluate acceleration characteristics of the human hand during quick arm motion. First, the dynamic manipulability of end-point via muscle forces, called Human Muscular Mobility Ellipsoid (HMME), is newly defined. Next, the direction-dependent acceleration characteristic of the human hand motion is examined and analyzed its geometrical properties with an approximation ellipses of measured data. It is also discussed the problem that the conventional measures relative to the performance of end-point acceleration cannot represent the geometrical properties of human generated hand acceleration in good agreement with the measured data. Finally, the merits of HMME compared with the conventional measures is then demonstrated with a set of experimental results and computed results: HMME can be utilized in representing the geometric properties of human hand acceleration.