著者

上野谷 敏之 水谷 義弘

出版者

公益社団法人 日本材料学会

雑誌

材料 (ISSN:05145163)

巻号頁・発行日

vol.55, no.3, pp.341-347, 2006 (Released:2006-04-26)

参考文献数

50

被引用文献数

1

著者

高島 成二

出版者

公益社団法人 日本薬理学会

雑誌

日本薬理学雑誌 (ISSN:00155691)

巻号頁・発行日

vol.124, no.2, pp.69-75, 2004 (Released:2004-07-26)

参考文献数

5

被引用文献数

2

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循環器領域においてアンジオテンシンIIは重要な役割を担うことが知られている.特に強い生理作用とあわせてシグナル阻害薬が高血圧や心不全の治療に使用されていることからその作用メカニズムを知ることは循環器疾患を考える上で重要である.心筋細胞におけるアンジオテンシンIIの役割はそのGタンパク共役型受容体を介すると考えられており,その結果として心筋細胞の肥大をきたす.しかし,タンパク合成を必要とする肥大反応にG共役型受容体を介する比較的一時的で敏速な細胞シグナルが関与することは特異的なシグナル経路の存在を示唆する.私はアンジオテンシンIIによる心筋肥大シグナルにEGFファミリーに属するHB-EGFという増殖因子が関与することを明らかにした.HB-EGF(heparine binding EGF-like Growth Factor)はG共役型受容体の刺激により細胞膜からメタロプロテアーゼにより分解して遊離され,心筋細胞の肥大を引き起こすことが明らかになった.さらにこのHB-EGFの細胞膜からの遊離が起こらない遺伝子改変マウスを作成すると,このマウスは生後4週ぐらいから徐々に心筋細胞の変性·脱落をきたし,心不全により早期に死亡した.これらの事実はHB-EGFが心筋細胞の肥大をきたすのみならず心筋細胞の代謝·維持に重要な働きを担うことを示唆する.AngiotensinIIなどの刺激によるシグナルはHB-EGFを介していかなる心筋細胞代謝を司るかを概説し,新しい心不全治療の可能性を検討する.

著者

田村 泰盛 服部 誠 今野 浩太郎 本田 洋 河野 義明

出版者

日本応用動物昆虫学会

雑誌

日本応用動物昆虫学会誌 (ISSN:00214914)

巻号頁・発行日

vol.48, no.3, pp.191-199, 2004 (Released:2004-11-30)

参考文献数

32

被引用文献数

8 8

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The leaf beetle Ophraella communa is an oligophagous insect that infests several asteraceous plants, especially ragweed Ambrosia artemisiifolia, in fields of Japan. The feeding responses of O. communa to methanolic extracts of 11 genera and 17 species of asteraceous plants were examined to determine whether feeding preference depended on chemicals in the plants. The methanolic extracts of 8 asteraceous species stimulated feeding in O. communa, but the other 9 species showed no activity. Two triterpenoids (α-amyrin acetate and β-amyrin acetate) and two caffeic acid derivatives (chlorogenic acid and 3,5-dicaffeoylquinic acid) are known as feeding stimulants for O. communa. The distribution of these compounds was analyzed in 17 asteraceous species. These compounds were found in many species, including nonhost plants of this beetle, however amounts and compositions differed. Even when the methanolic extracts of A. artemisiifolia were added to extracts of some species which did not elicit feeding of O. communa, the feeding of O. communa was not induced by the inactive plants. Feeding deterrents as well as feeding stimulants in the leaves of asteraceous plants appear to determine the feeding preference of O. communa.

著者

Masahiko Watanabe Yoshio Hirai

出版者

JAPANESE SOCIETY OF APPLIED ENTOMOLOGY AND ZOOLOGY

雑誌

Applied Entomology and Zoology (ISSN:00036862)

巻号頁・発行日

vol.39, no.2, pp.249-254, 2004 (Released:2004-08-25)

参考文献数

14

被引用文献数

12 22

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Host-use pattern for overwintering and reproduction of the ragweed beetle, Ophraella communa LeSage, was examined in Tsukuba, Japan. Many adults of both sexes were found overwintering inside the rolled parts of dead leaves of Xanthium canadense in November. These adults had already accumulated triacylglycerol as energy reserves, and were able to survive the winter and to reproduce in the spring. No eggs and larvae were found on X. canadense throughout the observation period, although overwintered adults were temporarily found in May. In contrast, reproduction occurs on Ambrosia artemisiifolia and A. trifida in late April. These results suggest that O. communa adults mainly use dead leaves of X. canadense as an overwintering shelter in Tsukuba, while they reproduce only on A. artemisiifolia and A. trifida in the spring. Such a seasonal migration between host plants may be important for the survival strategy.

著者

古賀 崇

出版者

国立研究開発法人 科学技術振興機構

雑誌

情報管理 (ISSN:00217298)

巻号頁・発行日

vol.47, no.11, pp.761-762, 2005 (Released:2005-02-01)

著者

近藤 隆二郎 守谷 光平

出版者

公益社団法人 日本造園学会

雑誌

ランドスケープ研究 (ISSN:13408984)

巻号頁・発行日

vol.66, no.5, pp.711-714, 2003 (Released:2003-09-24)

参考文献数

12

被引用文献数

1 1

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In this research, walking trail is analyzed from “sense of walking” paying attention to “the change nature of walking trail.” Analysis is precedence research in a soundscape. It carried out to reference from the viewpoint of a “sound”, a “phrase”, “harmony”, and a “melody.” This is because it is necessary to take in time progress about the correlation and analysis result of the composition element of “walking trail” seen from “sense of walking” to regard as a sequence. As a result of analysis, the acquired knowledge is summarized to below. (1) as the “harmony” of walking trail, eight types; “Circuit type”, “Relax type”, “Straight-flat type”, “Approach type”, “Well-textured straight-flat type”, “Acrobatic type”, “Up and down type”, and “Particular type” were extracted (2) consequently, high “harmony” of the rate for which it accounts on a “course”—“Circuit type” and “Relax type” (3) The type of six “melodies” was extracted as changes of “harmony.” (4) It became clear to correspond with the impression acquired by the feature of the type of the “harmony” obtained from “a sense of walking” actually walking that. When improving walk space, it can be said that the space which can obtain many feelings not only from vision but from body nature including “walk feeling” is very rich space.

著者

孫 成權:著 内田 尚子:訳

出版者

国立研究開発法人 科学技術振興機構

雑誌

情報管理 (ISSN:00217298)

巻号頁・発行日

vol.44, no.10, pp.701-701, 2002 (Released:2002-01-01)

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中国国家革新システムは科学,教育および持続的な開発を通して中国を活性化し,かつ中国における経済社会的発展の速度を高めるために中国政府が下した重要な国家の戦略である。同システムは知識革新と技術革新に関与する機関で構成されるネットワーキングシステムである。この中にあって1998年,中国政府は中国科学院による知識革新計画パイロットプロジェクトの開始を承認した。本稿では,中国科学院が国家革新システムにおいて与えられている歴史的任務,同プロジェクトに関する全体計画を述べる。次にプロジェクトの初期段階,実行段階について述べる。初期の段階ではかってない規模での中国科学院傘下の研究所の配置の再調整,統合がなされ,これまで37あった研究所が17の研究所に再編成された。また39の研究所が独立法人として同プロジェクトの機構に入ることが承認された。実行段階では次の項目についてそれぞれの目標を設定した。科学技術革新,人材育成,国の内外での人材交流,技術移転の促進,革新的文化の発展および科学技術基盤構造の構築。

著者

Kazuaki Miura

出版者

Japan Oil Chemists' Society

雑誌

Journal of Oleo Science (ISSN:13458957)

巻号頁・発行日

vol.56, no.3, pp.123-128, 2007 (Released:2007-02-10)

参考文献数

11

被引用文献数

3 8

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The aquatic risk of 2-sulfonato fatty acid methyl ester sodium salt (MES) used in household detergents was assessed. The environmental exposure assessment expressed as predicted environmental concentration (PEC) was determined on the basis of monitoring results from the seven sites of four rivers in the urban area in Tokyo and Osaka. The 95 percentile as well as geometric mean of the MES concentration was found to exhibit a good correlation with the geometric mean of the Biochemical Oxygen Demand (BOD; the latter’s regression was grater than 0.99). The predicted no effect concentration (PNEC) for the aquatic environment was estimated by performing chronic assays of algae and daphnia. The risk characterization ratio (RCR: PEC/PNEC) was less than 1. Therefore, it is concluded that MES will not adversely affect the aquatic environment in Japan.

著者

長谷川 秀記

出版者

国立研究開発法人 科学技術振興機構

雑誌

情報管理 (ISSN:00217298)

巻号頁・発行日

vol.47, no.1, pp.53-55, 2004 (Released:2004-04-01)

著者

川端 猛 西川 建

出版者

一般社団法人 日本生物物理学会

雑誌

生物物理 (ISSN:05824052)

巻号頁・発行日

vol.40, no.1, pp.52-56, 2000-01-25 (Released:2000-04-12)

参考文献数

7

被引用文献数

1 1 1

著者

Tetsuji Kuboyama Kouichi Hirata Hisashi Kashima Kiyoko F.Aoki-Kinoshita Hiroshi Yasuda

出版者

The Japanese Society for Artificial Intelligence

雑誌

Transactions of the Japanese Society for Artificial Intelligence (ISSN:13460714)

巻号頁・発行日

vol.22, no.2, pp.140-147, 2007 (Released:2007-01-25)

参考文献数

17

被引用文献数

5 11 27

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Learning from tree-structured data has received increasing interest with the rapid growth of tree-encodable data in the World Wide Web, in biology, and in other areas. Our kernel function measures the similarity between two trees by counting the number of shared sub-patterns called tree q-grams, and runs, in effect, in linear time with respect to the number of tree nodes. We apply our kernel function with a support vector machine (SVM) to classify biological data, the glycans of several blood components. The experimental results show that our kernel function performs as well as one exclusively tailored to glycan properties.

著者

Shin-ichi Minato Kimihito Ito

出版者

The Japanese Society for Artificial Intelligence

雑誌

Transactions of the Japanese Society for Artificial Intelligence (ISSN:13460714)

巻号頁・発行日

vol.22, no.2, pp.156-164, 2007 (Released:2007-01-25)

参考文献数

17

被引用文献数

2 4

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In this paper, we present a method of finding symmetric items in a combinatorial item set database. The techniques for finding symmetric variables in Boolean functions have been studied for long time in the area of VLSI logic design, and the BDD (Binary Decision Diagram) -based methods are presented to solve such a problem. Recently, we have developed an efficient method for handling databases using ZBDDs (Zero-suppressed BDDs), a particular type of BDDs. In our ZBDD-based data structure, the symmetric item sets can be found efficiently as well as for Boolean functions. We implemented the program of symmetric item set mining, and applied it to actual biological data on the amino acid sequences of influenza viruses. We found a number of symmetric items from the database, some of which indicate interesting relationships in the amino acid mutation patterns. The result shows that our method is helpful for extracting hidden interesting information in real-life databases.

著者

Shin-ichi Minato Hiroki Arimura

出版者

The Japanese Society for Artificial Intelligence

雑誌

Transactions of the Japanese Society for Artificial Intelligence (ISSN:13460714)

巻号頁・発行日

vol.22, no.2, pp.165-172, 2007 (Released:2007-01-25)

参考文献数

11

被引用文献数

1 5 9

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Frequent item set mining is one of the fundamental techniques for knowledge discovery and data mining. In the last decade, a number of efficient algorithms for frequent item set mining have been presented, but most of them focused on just enumerating the item set patterns which satisfy the given conditions, and it was a different matter how to store and index the result of patterns for efficient data analysis. Recently, we proposed a fast algorithm of extracting all frequent item set patterns from transaction databases and simultaneously indexing the result of huge patterns using Zero-suppressed BDDs (ZBDDs). That method, ZBDD-growth, is not only enumerating/listing the patterns efficiently, but also indexing the output data compactly on the memory to be analyzed with various algebraic operations. In this paper, we present a variation of ZBDD-growth algorithm to generate frequent closed item sets. This is a quite simple modification of ZBDD-growth, and additional computation cost is relatively small compared with the original algorithm for generating all patterns. Our method can conveniently be utilized in the environment of ZBDD-based pattern indexing.

著者

尾崎 知伸 渡沼 智己 大川 剛直

出版者

一般社団法人 人工知能学会

雑誌

人工知能学会論文誌 (ISSN:13460714)

巻号頁・発行日

vol.22, no.2, pp.173-182, 2007 (Released:2007-01-25)

参考文献数

43

被引用文献数

1

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Recently, the research area of mining in structured data has been actively studied. However, since most techniques for structured data mining so far specialize in mining from single structured data, it is difficult for these techniques to handle more realistic data which is related to various types of attribute and which consists of plural kinds of structured data. Since such kind of data is expected to be going to rapidly increase, we need to establish a flexible and highly accurate technique that can inclusively treat such kind of data. In this paper, as one of the techniques to deal with such kind of data, we propose data mining algorithms of mining classification rules in multidimensional structured data. First, an algorithm with two pruning capabilities of mining correlated patterns is introduced. Then, top-k multidimensional correlated patterns are discovered by using this algorithm repeatedly in the fashion like a beam search. We also show the algorithms for constructing classifiers based on the discovered patterns. Experiments with real world data were conducted to assess the effectiveness of the proposed algorithms. The results show that the proposed algorithms can construct comprehensible and accurate classifiers within a reasonable running time.

著者

Nozomi Kobayashi Kentaro Inui Yuji Matsumoto

出版者

The Japanese Society for Artificial Intelligence

雑誌

Transactions of the Japanese Society for Artificial Intelligence (ISSN:13460714)

巻号頁・発行日

vol.22, no.2, pp.227-238, 2007 (Released:2007-01-25)

参考文献数

19

被引用文献数

3 17 38

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The task of opinion extraction and structurization is the key component of opinion mining, which allow Web users to retrieve and summarize people's opinions scattered over the Internet. Our aim is to develop a method for extracting opinions that represent evaluation of concumer products in a structured form. To achieve the goal, we need to consider some issues that are relevant to the extraction task: How the task of opinion extraction and structurization should be designed, and how to extract the opinions which we defined. We define an opinion unit consisting of a quadruple, that is, the opinion holder, the subject being evaluated, the part or the attribute in which it is evaluated, and the evaluation that expresses positive or negative assessment. In this task, we focus on two subtasks (a) extracting subject/aspect-evaluation relations, and (b) extracting subject/aspect-aspect relations, we approach each extraction task using a machine learning-based method. In this paper, we discuss how customer reviews in web documents can be best structured. We also report on the results of our experiments and discuss future directions.

著者

北川 えみ 北川 忠生 能宗 斉正 吉谷 圭介 細谷 和海

出版者

公益社団法人 日本水産学会

雑誌

日本水産学会誌 (ISSN:00215392)

巻号頁・発行日

vol.71, no.2, pp.146-150, 2005 (Released:2005-07-15)

参考文献数

15

被引用文献数

5 2

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1988 年にオオクチバスフロリダ半島産亜種が放流された池原貯水池では,1996, 1997 年の遺伝学的調査においてフロリダ半島産亜種由来のミトコンドリア DNA(mtDNA)をもつ個体の割合は 56.8% であった。今回(2003 年)再調査を行った結果,本亜種由来の mtDNA をもつ個体は全体の 86.7% となり,前回調査より有意な増加がみとめられた。また,近畿地方の池原貯水池とは別水系の湖沼(津風呂湖,宝ヶ池,深泥池)からも本亜種由来の mtDNA をもつ個体が検出された。

著者

河野 俊夫 疋田 慶夫

出版者

日本生物環境工学会

雑誌

植物環境工学 (ISSN:18802028)

巻号頁・発行日

vol.17, no.1, pp.19-25, 2005 (Released:2006-03-01)

参考文献数

11

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Storage tests were conducted under a temperature range of 4 to 16℃ (to 12℃ for ‘Unshiu’) for three kinds of citrus fruits: ‘Kiyomi’, ‘Unshiu’ and ‘Amanatsu’ Fruits for the tests were stored in air-tight container for 6 hrs,and change in the temperature and humidity in the head air space in the container was measured to evaluate the quantity of moisture transpiration from fruits under dynamically fluctuating moisture conditions caused by transpiration.Based on the equation for defining moisture transpiration resistance for plants, moisture transpiration resistances for tested citrus fruits were calculated and the values were plotted against vapor pressure difference between the head space air and fruit surface. The resulted figure showed moisture transpiration resistance for citrus fruit exponentially increases as the vapor pressure difference decreases. Then an empirical non-linear approximation equation was proposed and its parameters for each citrus fruit were obtained by the Marquardt method. Parameters in the equation were dependent on storage temperature and the slopes of parameters against storage temperature were similar for all types of fruit tested. The relationships were also arranged in the form of a linear equation with two parameters.

著者

後藤 晃範 大島 光子 高柳 俊夫 本水 昌二

出版者

公益社団法人 日本分析化学会

雑誌

分析化学 (ISSN:05251931)

巻号頁・発行日

vol.53, no.9, pp.919-923, 2004 (Released:2004-12-24)

参考文献数

14

被引用文献数

1 1

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水溶液一相系でイオン会合反応を利用する陰イオン界面活性剤直接定量のための陽イオン性染料を新規に合成した.基本骨格はシアニンとし,二つのNに炭素数の異なるn -アルキル鎖を導入した四級塩染料を合成した.アルキル鎖の炭素数4と6のものは新規合成化合物であり,pKaを求めた.炭素数2と3の市販品と合成した陽イオン試薬を用い,吸光光度法により陰イオン界面活性剤(DBS)との最適反応条件を検討した.3,3'-ジヘキシル-2,2'-チアシアニン(DHT,C6の試薬)を用いて,10-6 MオーダーのDBSを定量することができ,検出下限は4×10-7 Mであった.また,疎水性相互作用により,非イオン性界面活性剤,陽イオン界面活性剤とも反応することが分かり,DHTとのイオン会合定数を求めた.

著者

菱川 明栄

出版者

社団法人 プラズマ・核融合学会

雑誌

プラズマ・核融合学会誌 (ISSN:09187928)

巻号頁・発行日

vol.80, no.9, pp.742-748, 2004 (Released:2005-07-14)

参考文献数

18

被引用文献数

2 1

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The structures of rotational and vibrational energy levels and the term symbols to classify different electronic states are described for diatomic molecules. Different classes of parity, (+/−), (e/f) and (s/a), associated with each rovibronic level are discussed. The transition probability, the Franck-Condon factors, the Hönl-London factors and the transition moments of electronic transitions and their selection rules are described.