著者
Victor Alexandrovich Kondratovitch Pavel Yevgenyevich Korotkevich Yuriy Yevgenyevich Demidchik Vladimir Stepanovich Karanik Aliaksandr Gennadievich Zhukavets
出版者
日本内分泌外科学会・日本甲状腺外科学会
雑誌
日本内分泌・甲状腺外科学会雑誌 (ISSN:21869545)
巻号頁・発行日
vol.35, no.2, pp.90-103, 2018 (Released:2018-08-24)
参考文献数
25

The objective of the study was to explore the impact of the surgery volume on the course and outcome of the papillary thyroid cancer depending on the risk factors. This is a retrospective study with 3,266 successive cases of papillary thyroid cancer registered from 1990 till 2005 in subjects residing in Minsk or Minsk Region at the moment of diagnosing, with a medium observation of 10.2 years. In the group of postoperative patients, 5-, 10- and 20-year cause-specific survival was 99.0±0.2%, 98.0±0.2%, 97.3±0.6%, and cumulative relapse rate was 6.0±0.5%, 8.2±0.6%, 14.3±1.5%, respectively. Life expectancy of patients with papillary thyroid cancer is mainly established by the independent prognostic factors, and not by the volume of surgical intervention, which is related to the early diagnosing of a relapse and timely performed repeated surgery. The key factors defining the risk of death due to cancer are age over 55 years in women (PR=30.08, p<0.0001) , and 35 years (PR=22.15, p<0.0001) in men, presence of distant metastasis (p<0.0001) , and massive extrathyroidal extension of a tumour (p<0.0001) . Metastatic involvement of regional lymph nodes 7.26-fold increases the risk of relapse (p<0.0001) and is a key prognostic factor. Organ preservation surgeries 3.3-fold increase the risk of relapse (p<0.0001) , and absence of lymph node dissection - 2.85-fold (p<0.0001) .Conclusions:1. Age, distant metastasis, and massive extrathyroidal extension are the key independent prognostic factors, which define the risk of death due to papillary thyroid cancer. The age of 55 years for women and of 35 years for men can be more accurately used for division of patients between the prognostic groups.2. Thyroidectomy and bilateral lymph node dissection significantly reduce the risk of relapse, but statistically do not influence the cause-specific survival.3. Presence of metastasis in the regional lymph nodes is a decisive factor of relapse. It testifies to insufficiently removed level III and level IV lymph nodes in case of any signs of their metastatic affection, and requires an extension of the lymph node dissection volume in such patients.
出版者
国立国会図書館
雑誌
技術と文化による日本の再生 : インフラ、コンテンツ等の海外展開
巻号頁・発行日
vol.国際政策セミナー「世界経済の動向と日本の成長戦略」報告書, 2012-09
著者
武富 卓三 山海 嘉之
出版者
公益社団法人 日本生体医工学会
雑誌
生体医工学 (ISSN:1347443X)
巻号頁・発行日
vol.50, no.1, pp.105-110, 2012-02-10 (Released:2012-07-13)
参考文献数
7
被引用文献数
2

The purpose of this study is to propose a method of a walking assistance by using an exoskeletal system “Hybrid Assistive Limb (HAL)” for cerebral palsy (CP) patients who cannot stand up and walk due to the abnormal generation of the bioelectrical signals (BES) in their lower limbs associated with the brain disease, and to verify the effectiveness of the proposed method through a clinical trial. HAL was developed to support the voluntary movement of the wearer based on the BES. The proposed method consists of two algorithms, that is, an assistance of voluntary movement in the swing phase and an assistance of weight bearing in the stance phase. The assistance of the voluntary movement determines the rotational direction of the actuator from the ratio of the abnormal BES by using sigmoid function during the swing phase. On the other hand, the assistance of the weight bearing adjusts automatically the stiffness and viscosity of the joint during the stance phase. In the clinical walking trial with a 3-meter walk using parallel bars, we confirmed that HAL including the proposed method achieved the patient's walking assistance. Especially, the assistance of the voluntary movement in the swing phase produced his leg-swing based on the BES signals. As a result, the walking speed, cadence and stroke width of the patient with HAL during this trial are 1.6m/min, 11.4 steps/min and 0.14m, respectively. In conclusion, we have proposed the method of the walking assistance method and thus, confirmed the effectiveness of the proposed method.
著者
森 邦昭
出版者
福岡女子大学
雑誌
文芸と思想 (ISSN:05217873)
巻号頁・発行日
vol.76, pp.A103-A123, 2012-02-27
著者
小林 茂雄 津田 智史
出版者
日本建築学会
雑誌
日本建築学会環境系論文集 (ISSN:13480685)
巻号頁・発行日
vol.72, no.615, pp.65-71, 2007
被引用文献数
1

This research examined the interpersonal distances from others desired by couples sitting on a hill by the sea. An investigation to observe the behavior of actual couples, and an experiment to assess their feelings were carried out in the early evening and the nighttime. In the results, the following points were demonstrated. 1) The closest distance the couples could allow others to approach was 2 to 3 meters in all directions, and the distance at which couples were not annoyed by others was about 5 meters in all directions, 2) When the distances with others were within about 5 meters, the time a couple stayed in their spot was affected by others. The effects were stronger when the others were in front of a couple or behind them in the nighttime. 3) When the distances from others were within 5 to 6 meters, the couple's intimate contact was affected by others. The distances were a little larger in the early evening than in the nighttime, and women preferred larger distances than men.
著者
Tatsumi Suguro Yuki G. Baba Takeo Yamauchi
出版者
Arachnological Society of Japan
雑誌
Acta Arachnologica (ISSN:00015202)
巻号頁・発行日
vol.67, no.1, pp.19-21, 2018-08-31 (Released:2018-09-05)
参考文献数
11
被引用文献数
1

A phrurolithid spider species, Phrurolithus splendidus Song & Zheng 1992, is newly recorded from Japan. This species resembles P. pennatus, but can be distinguished from the latter by male tibial apophysis with thin finger-shaped apex, and spermathecae located behind openings.
著者
大森 直樹 大橋 保明
出版者
東京学芸大学
雑誌
基盤研究(C)
巻号頁・発行日
2017-04-01

首都圏の学校における東京電力福島第一原子力発電所事故の影響と課題を明らかにすることが本研究の目的である。平成29年度は、①環境省の汚染状況重点地域の指定が群馬・栃木・茨城・千葉・埼玉に及んでいる事実をふまえ、②国民文化総合研究所(2016)が提起した「原発被災校A」(福島725校)の概念を手がかりとして、③群馬・茨城・千葉における学校数および学校別児童生徒数の一覧の作成をおこない(2017年度群馬569校・茨城837校・千葉1346校)、④2017年度の「原発被災校A」が群馬160校・茨城428校・千葉342校に及ぶことを明らかにした。⑤首都圏の「原発被災校A」における課題については、保護者を中心として原発事故の子どもへの影響と学校の課題に関して取り組みを重ねてきた「放射能からこどもを守ろう関東ネット」(2012年12月発足)や「関東子ども健康調査支援基金」(2013年9月発足)へのヒアリング調査をおこない、学校における空間線量の測定、学校における土壌汚染の測定、野外活動の制限、学校給食の安全、被ばくによる子どもの健康への影響を知るための健康診断などの諸課題について、現状を明らかにするための手がかりを得た。今後は、上記した①②③④をふまえて、⑥栃木・埼玉における学校数および学校別児童生徒数の一覧の作成をおこない、⑦栃木・埼玉における「原発被災校A」の実数についても明らかにする。また、⑤をふまえて、「原発被災校A」が所在する首都圏の自治体の事例研究をおこない、課題の解明をすすめていく。
著者
斎藤 幸雄 柴 光年 山川 久美 馬場 雅行 木村 秀樹 藤沢 武彦 山口 豊 大和田 英美
出版者
The Japanese Respiratory Society
雑誌
日本胸部疾患学会雑誌 (ISSN:03011542)
巻号頁・発行日
vol.29, no.1, pp.95-100, 1991-01-25 (Released:2010-02-23)
参考文献数
12
被引用文献数
2

症例は60歳男性, 主訴は乾性咳嗽, 胸部X線写真にて右上肺野に腫瘤影が認められ, 気管支鏡検査で気管浸潤を伴う右S1原発の肺癌と診断された. 化学療法 (CDDP+VDS) 1クール, 続いて放射線療法 (50Gy) が施行されたがいずれの療法も奏効せず腫瘍の増大による気管圧迫のため呼吸困難が出現し, また上肢および体幹部に皮膚転移巣が多発した. 救命的にNd-YAGレーザーで気道の開大を行い呼吸困難および全身状態の改善が得られたため, 皮膚転移巣に対してはエタノールの局所注入あるいは摘出を行い退院となった. 外来での経過観察中 (退院時より約2ヵ月間) に残存する全ての皮膚転移巣が消失し, 続いて原発巣も退縮を示した. 現在, 発見から5年経過したが臨床的には腫瘍の再増殖は認められず健在である. 退縮の機転に関しては明らかではないが, 本症例は極めて稀な肺癌の自然退縮例であると考え報告した.
著者
MARRA Claudia
出版者
長崎外国語大学
雑誌
長崎外大論叢 = The Journal of Nagasaki University of Foreign Studies (ISSN:13464981)
巻号頁・発行日
no.20, pp.47-55, 2016-12-30

AbstractEven considering Japan’s high literacy rates during the early modern period, it is rather unlikely, that the majority of the Japanese population would have been able to read and understand an important Buddhist text like the Heart Sutra, 般若心経. This naturally posed a problem for the monastic schools, who competed with the rather easy to practice Pure Land and Amida schools, and needed to become more accessible to their lay-supporters. An answer to this problem presented itself in the form of Hanjimono (判じ物), rebus-like allusions, using pictures to represent words or parts of words. Usually used for playfull riddles, artists would also use Hanjimono to represent their names and sometimes even short subversive slogans. It were monks from the Tohoku area who adopted Hanjimono to represent the Heart Sutra and thus helped to make it accessible to the illiterate lay people. The considerations behind that practice are topic of this paper.概要江戸時代に日本の高い識字率にもかかわらず、一般の日本人は般若心経の様な代表的な仏教の経文を読める事が不可能であっただろう。この問題を解決するために普段言葉遊びに使われた判じ物が利用される事になった。東北の寺で制作が始まった判じ物の絵般若心経は全国に広まった。この絵般若心経の意図するところを明らかにするのが、本論文のテーマである。