著者

高屋 定美

出版者

比較経済体制学会

雑誌

比較経済研究 (ISSN:18805647)

巻号頁・発行日

vol.47, no.2, pp.2_27-2_37, 2010 (Released:2011-02-18)

参考文献数

15

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本稿では,米国のサブプライム危機から派生した欧州の金融・経済危機の構造的要因を分析している.構造的要因として,経済構造の相違があるままに単一通貨を導入したことや,金融統合によって欧州の金融機関の競争環境が激化したこと,そして中東欧諸国への EU 拡大などが挙げられ,それらを実証的に解明している.さらに欧州中央銀行,欧州委員会ならびに,各国政府が行っている危機対応の経済対策について展望している.

著者

Masahiro MIYABE Azusa GIN Eri ONOZAWA Mana DAIMON Hana YAMADA Hitomi ODA Akihiro MORI Yutaka MOMOTA Daigo AZAKAMI Ichiro YAMAMOTO Mariko MOCHIZUKI Toshinori SAKO Katsutoshi TAMURA Katsumi ISHIOKA

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.15-0031, (Released:2015-05-10)

被引用文献数

2 11

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G protein-coupled receptor (GPR) 120 is an unsaturated fatty acid receptor, which is associated with various physiological functions. It is reported that the genetic variant of GPR120, p.Arg270His, is detected more in obese people, and this genetic variation functionally relates to obesity in humans. Obesity is a common nutritional disorder also in dogs, but the genetic factors have not ever been identified in dogs. In this study, we investigated the molecular structure of canine GPR120 and searched for candidate genetic variants which may relate to obesity in dogs. Canine GPR120 was highly homologous to those of other species, and seven transmembrane domains and two N-glycosylation sites were conserved. GPR120 mRNA was expressed in lung, jejunum, ileum, colon, hypothalamus, hippocampus, spinal cord, bone marrow, dermis and white adipose tissues in dogs, as those in mice and humans. Genetic variants of GPR120 were explored in client-owned 141 dogs, resulting in that 5 synonymous and 4 non-synonymous variants were found. The variant c.595C>A (p.Pro199Thr) was found in 40 dogs, and the gene frequency was significantly higher in dogs with higher body condition scores, i.e. 0.320 in BCS4-5 dogs, 0.175 in BCS3 dogs and 0.000 in BCS2 dogs. We conclude that c.595C>A (p.Pro199Thr) is a candidate variant relating to obesity, which may be helpful for nutritional management of dogs.

著者

大山 勝宏 清水 万紀子 山崎 浩史

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.40, no.5, pp.310-316, 2014-05-10 (Released:2015-05-10)

参考文献数

18

被引用文献数

1 1

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A retrospective survey of a database containing patient backgrounds and prescribed drugs was conducted to elucidate the detailed characteristics and risk factors of adverse effects caused by topical dermatological formulations of diclofenac. A total of 145,478 patients who had been dispensed topical dermatological formulations of diclofenac at 466 community pharmacies belonging to Nihon Chouzai were included in the study. Of these, 580 patients had adverse effects. The incidence of adverse effects was significantly higher in the elderly (more than 65 years old) and in female patients. A variety of systemic adverse effects were evident in 19 patients. Approximately half of these adverse effects were related to the respiratory system, eg, asthma, but the other adverse effects (eg, edema, decreases in urinary volume, tremor and others) were not described in the drug package inserts. Data from patients with systemic adverse effects, and an age- and gender-matched control group of patients underwent multivariate logistic regression analysis. Asthma (odds ratio: 13.3, 95% confidence interval: 2.40 - 95.5, P = 0.004) and the number of co-administered drugs (odds ratio: 1.25, 95% confidence interval: 1.02 - 1.55, P = 0.035) were identified as risk factors for systemic adverse effects of topical dermatological formulations of diclofenac. Moreover, many of the co-administered drugs affected P450 enzymes other than P450 2C9, the main metabolizer of diclofenac. Therefore, to manage the risk of adverse events, it was concluded that various characteristics of concomitant medications and patient's medical history should be evaluated properly before topical dermatological formulations of diclofenac are prescribed.

著者

海崎 彩

出版者

一般社団法人 日本温泉気候物理医学会

雑誌

日本温泉気候物理医学会雑誌 (ISSN:00290343)

巻号頁・発行日

vol.77, no.2, pp.127-142, 2014-02-28 (Released:2014-06-26)

参考文献数

33

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背景・目的 : 夏季暑熱環境下では食物摂取が減少し、体格や競技力に影響を及ぼす可能性がある。そこで、夏季の食物摂取の減少について調査し、体格に及ぼす影響を調べるとともにエネルギー代謝や甲状腺ホルモンとの関連について検討した。方法 : 高校硬式野球部に所属する男子生徒を対象として、春季~冬季にわたり栄養調査、身体計測、生活時間調査(AC : activity record)を3回行った。さらに、安静時エネルギー代謝量(REE : resting energy expenditure)、甲状腺ホルモンを測定し、エネルギー(E)摂取との関連を調べた。栄養調査からE摂取量を計算し、ACから総エネルギー消費量(TEE : total enregy expenditure)を算出し、エネルギー(E)バランスを決定した。またREEは呼気ガス分析により測定し、甲状腺ホルモンはT3、FT3、FT4を定量した。結果 : 夏季のE摂取の減少は、約70%の選手で起こったので、E摂取が減少した群をLA、減少しなかった群をHAとした。TEEは両群ともに夏季に増加したので、E摂取が減少したLAではEバランスは有意に低下し負に傾いた(約-690kcal/day)。彼らの体重および上腕周囲長はそれぞれ春季よりも有意に減少し(p<0.05)、その減少率は約2~4%であった。食事のエネルギー構成比率は、LAでは高炭水化物食、HAでは高脂肪食の傾向であった。また、E摂取が減少すると、マクロ栄養素もミクロ栄養素も減少した。REEは、夏季に有意に減少し、E摂取の減少と関連することが示唆された。一方、T3、FT3は、夏季には変化はなかったが、冬季に有意に上昇しREEとの関連が見られた。結論 : 夏季環境下におけるE摂取の減少は、体重および上腕周囲長の減少を引き起こし、体格に影響を与えた。E摂取の減少は、REEの低下と関連することが示唆された。

著者

大倉 典子 後藤 さやか 肥後 亜沙美 青砥 哲朗

出版者

自動制御連合講演会

雑誌

自動制御連合講演会講演論文集 第52回自動制御連合講演会

巻号頁・発行日

pp.126, 2009 (Released:2010-01-22)

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「かわいい」という感じ方に差のある人工物の画像をバーチャル環境で被験者に提示して、それをかわいいと感じた場合とそうでない場合の被験者の生体信号を比較した。 その結果、かわいいと感じた場合とそうでない場合とで、心拍やMidα波に差のあることがわかった。

著者

橋本 徹夫 菊地 正幸

出版者

公益社団法人 東京地学協会

雑誌

地学雑誌 (ISSN:0022135X)

巻号頁・発行日

vol.111, no.1, pp.118-125, 2002-02-25 (Released:2009-11-12)

参考文献数

17

被引用文献数

1 1

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Subevents of the 1946 Nankai earthquake (Mjma8.0) were distinguished from seismograms recorded on smoked papers with strong motion seismograms (T0=6s, amplification=2) and seismological data of Japan Meteorological Agency. Location and origin time of each subevent were roughly estimated from a hypocenter determination with phase readings of P and S waves for the subevent. Rupture of the Nankai earthquake started at a point southward about 50km off Cape Shionomisaki (first subevent). The rupture propagated in the NNW direction with a rupture velocity of 1.9 km/s and a second subevent that grew to class M8 started after about 16 sec from the initiation of the first subevent. Then the rupture propagated westward, and third subevent of M8 occurred around Tosa Bay, located about 200 km from the second event, about 53 sec after the initiation of the second event. Seismic waves were excited near Tosa Bay during the 1946 Nankai earthquake.

著者

新潟古砂丘グループ

出版者

日本第四紀学会

雑誌

第四紀研究 (ISSN:04182642)

巻号頁・発行日

vol.6, no.1, pp.19-28, 1967-06-30 (Released:2009-08-21)

参考文献数

10

被引用文献数

1 3

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Sand beds which mainly consist of massive, consolidated and well-sorted sand are observed along the coast of the Japan Sea and are thought to be Pleistocene dunes. The writers call these dunes the “Ancient Dunes” in contrast with “Recent Dunes” of the Holocene epoch. The Ancient Dunes can be classified into two groups: the older “Ancient Dunes I” and the other “Ancient Dunes II” according to the different ages of formation.The Ancient Dunes I consists of grey, massive and consolidated medium sand, the lower part of which is occasionally aqueous, and is overlying on the middle terrace deposits almost conformably, although partly unconformably. The dunes of this group are found all along the coast of the Japan Sea from North Kyûshû to Aomori Prefecture, the northernmost of Honshû.The Ancient Dunes II consists of pale yollow fine sand with crepe-like texture, which is a characteristic feature of loessy sand. The dunes of this group are distributed at Yasuoka in Yamaguchi Prefecture and south of it while, along the northern coasts they are not found. There is brown weathered clay or volcanic ash overlying the Ancient Dunes I, which may be the equivalent to them in age.The stratigraphic relation between the sand beds of the Ancient Dunes and the terrace deposits or volcanic ash deposits suggests that the Ancient Dunes I and II are correlated to the Riss-Würm interglacial and the Würm glacial stages respectively. They are thought to have been formed the marine regression in glacial ages.

著者

吉田 勲

出版者

社団法人 農業農村工学会

雑誌

農業土木学会誌 (ISSN:03695123)

巻号頁・発行日

vol.64, no.12, pp.1220-1220, 1996-12-01 (Released:2011-08-11)

著者

別本 勝美

出版者

一般社団法人 日本風力エネルギー学会

雑誌

風力エネルギー (ISSN:03876217)

巻号頁・発行日

vol.30, no.3, pp.35-37, 2006 (Released:2011-01-27)

著者

岩田 勝哉

出版者

日本陸水学会

雑誌

陸水学雑誌 (ISSN:00215104)

巻号頁・発行日

vol.38, no.1, pp.19-32, 1977-01-30 (Released:2009-10-21)

参考文献数

26

被引用文献数

4 7

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By using unialgal culture of the two species of green algae (Closterium moniliferum : 300μ in length and Selenastrum sp. 10μ) which were labeled with 14C, the assimilation efficiency in terms of carbon of three cyprinids, Kawachibuna (Carassius auratus cuvieri), Nigorobuna (C. auratus grandoculis) and Silver carp (Hypophthalmichthys molitrix) was studied at the various life stages. In addition, radioactivities of different fractions (oligo-and poly-saccharides, organic acids, lipides, protein and residue) of the both species of 14C-algae and of the fecal algae egested by Kawachibuna and Silver carp were measured.In Kawachibuna and Nigorobuna, the assimilation efficiency for Closterium increased with their growth until they attained to 20 mm in total length (B. L. 14-15 mm), and reached the maximum level of more than 20 mm length (57-63%) at the successive stage. In Silver carp of 20 mm total length, the assimilation efficiency for Closterium was lower than for Kawachibuna and Nigorobuna of the same length. In Silver carp of more than 33 mm total length (B. L. 26-27 mm), 54-64% of carbon was assimilated.Kawachibuna and Silver carp are already known to change their food items from zooplankton to phytoplankton when they grow up more than 15 and 24 mm in body length respectively. The body length at which the maximum values of assimilation efficiency were obtained coincides approximately with the body length at which the change in diet occurs. It is suggested that the increase in the assimilation efficiency for Closterium with the growth of the fishes is not directly correlated with the increase in the length of their intestines but with a functional differentiation of their digestive systems.The three cyprinids assimilated 12-16% of carbon of Selenastrum and the rate was fairly stable throughout their lives, in contrast with those for Closterium. No difference was found in photosynthetic activity between fecal algae of Selenastrum egested by young Kawachibuna and fresh ones, while the activity of fecal algae of Closterium was approximately one-fifth of the fresh ones. The difference in assimilation efficiency may be related partly to the physiology of digestion of the cyprinids and partly to differences in chemical nature and cell structure of the two species of algae.

著者

橋本 亘

出版者

公益社団法人 東京地学協会

雑誌

地学雑誌 (ISSN:0022135X)

巻号頁・発行日

vol.74, no.6, pp.295-316, 1965-12-25 (Released:2009-11-12)

参考文献数

159

著者

Toyoaki Murohara

出版者

日本循環器学会

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

pp.CJ-15-0396, (Released:2015-05-11)

参考文献数

19

被引用文献数

3 4

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The 64thAnnual Scientific Sessions and Exposition of the American College of Cardiology (ACC) were held at the San Diego Convention Center from March 14–16, 2015. The ACC Scientific Sessions are 1 of 2 major scientific cardiology meetings in the United States, with nearly 20,000 attendees, including 15,000 cardiovascular professionals. There were over 2,100 oral and poster abstracts, and more than 15 late-breaking clinical trials (LBCTs) abstructs. This report presents the highlights and several key presentations, especially the LBCTs, from the ACC Scientific Sessions 2015. I hope this review will help cardiologists update to the latest information.

著者

古場 一哲

出版者

公益社団法人 日本油化学会

雑誌

オレオサイエンス (ISSN:13458949)

巻号頁・発行日

vol.10, no.11, pp.415-422, 2010-11-01 (Released:2013-06-01)

参考文献数

73

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これまでに, 共役リノール酸 (CLA) は, 発がん抑制, 体脂肪低減をはじめとする多彩な生理機能を示すことが動物実験により明らかにされ, その作用機序についてもある程度明らかにされてきている。中でも, 体脂肪低減作用はヒトでも有効性が報告され, とくに注目されている。CLAはリノール酸 (実際にはサフラワー油など) をアルカリ異性化して調製される。この方法では9c, 11t-18 : 2と10t12c18 : 2の2種類のCLA異性体がほぼ1 : 1の割合で生成する。市販のCLAもこの方法で調製されている。 CLAの生理機能は異性体によって異なり, 9c, 11t-8 : 2が発がん抑制など限られた効果しか示さないのに対し, 10t12c18 : 2は体脂肪低減を含む多彩な生理機i能を発揮する。CLAは天然には9c, 11t8 : 2として牛肉や乳製品に微量 (5mg/g脂質程度) 存在するが, これらは量的にも重要な供給源とはならない。10t12c-異性体の体脂肪低減作用を期待してCLAサプリメントが国内外で市販されている。最近, CLAを配合した加工食品も市場に出始め, 機能性素材として, CLAは新たな局面を迎えている。

著者

櫻井 純理

出版者

Japan Society for Distributive Sciences

雑誌

流通 (ISSN:09149937)

巻号頁・発行日

vol.1998, no.11, pp.108-116, 1998 (Released:2010-08-05)

参考文献数

16

著者

田窪 重徳

出版者

公益社団法人 日本薬理学会

雑誌

日本薬理学雑誌 (ISSN:00155691)

巻号頁・発行日

vol.52, no.3, pp.238-244, 1956-05-20 (Released:2010-07-09)

参考文献数

21

著者

金井 雅仁 湯川 進太郎

出版者

公益財団法人 パブリックヘルスリサーチセンター

雑誌

ストレス科学研究 (ISSN:13419986)

巻号頁・発行日

vol.28, pp.55-65, 2013 (Released:2013-12-20)

参考文献数

24

被引用文献数

1

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In this study, we examined 1) whether the laughter affects the cognitive appraisal to stressful situations or not, 2) whether the effect is caused by mirth or physical expression, and 3) how the laughter, the cognitive appraisal, and the personalities are related. In the experiment, participants listened to a humorous or neutral auditory stimulus. After that they evaluated the imaginary stressful situations. In this study, there were three experimental conditions. In condition 1, participants listened to the neutral auditory stimulus and they didn't feel mirth. In condition 2, participants listened to the humorous stimulus and they felt mirth. In condition 3, participants listened to the stimulus used in condition 2. Furthermore, they were asked not to laugh. As a result, the laughter didn't affect the cognitive appraisal. However the data have shown that the cognitive appraisal correlated with the personalities differently in each condition. Thus, it is possible that the laughter affects the relationship between the cognitive appraisal and the personalities. We expect that the effect of the laughter will be examined by improved experiments in the future, while focusing on the personalities which seem to have relationship with the cognitive appraisal.

著者

Yasuo AKIZUKI

出版者

THE PHYSICAL SOCIETY OF JAPAN , The Mathematical Society of Japan

雑誌

Nippon Sugaku-Buturigakkwai Kizi Dai 3 Ki (ISSN:03701239)

巻号頁・発行日

vol.17, pp.337-345, 1935 (Released:2009-06-09)

出版者

一般社団法人 日本ペインクリニック学会

雑誌

日本ペインクリニック学会誌 (ISSN:13404903)

巻号頁・発行日

vol.18, no.3, pp.241-300_1, 2011-06-25 (Released:2011-10-14)

著者

会田 俊夫 藤尾 博重 高下 二郎

出版者

公益社団法人 精密工学会

雑誌

精密機械 (ISSN:03743543)

巻号頁・発行日

vol.31, no.360, pp.109-114, 1965-01-05 (Released:2010-02-16)

参考文献数

2

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Sintered metal is widely applied to mechanical parts and also to gears in special use. Bending strength and surface durability of sintered metal gears are, however, hardly discussed. Therefore, the authors carry out this test for the purpose of comparing bending strength and surface durability of sintered metal gears with those of hobbed carbon steel or cast iron gears.The test results make it clear that sintered metal gears have remarkably good characteristics on surface durability especially in the case of insufficient lubrication and its operating noise is smaller, although static and fatigue bending strength of sintered metal gears are lower than those of cast iron gears.

著者

村木 美貴 中井 検裕

出版者

公益社団法人 都市住宅学会

雑誌

都市住宅学 (ISSN:13418157)

巻号頁・発行日

vol.1998, no.23, pp.59-64, 1998-10-31 (Released:2012-08-01)

参考文献数

17

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This paper deals with affordable housing policies and their imprementation in inner London local planning authorities and attempts to clarify how development policies can contribute to this and also how planning department can corporate with housing department.The discussion begins with a general review of planning advantages, followed by an examination of affordable housing policies. Most of inner London authorities have three types of affordable housing policies: the size of site, the proportion of affordable housing and the use of planning agreement. From the analysis of practices, the planning departments negotiate with the applicants who have the large scale developments for securing affordable housing. These negotiations progress on the section 106 and their affordable housing requirements. Also it was found that the close liaison between planning and housing departments in local authorities for the implementation of affordable housing.