著者
Mike Dobson 河村 善也
出版者
日本第四紀学会
雑誌
第四紀研究 (ISSN:04182642)
巻号頁・発行日
vol.37, no.5, pp.385-395, 1998-12-31 (Released:2009-08-21)
参考文献数
37
被引用文献数
44 81

日本列島の哺乳動物相の歴史的発展過程を明らかにするために,Dobson(1994)はそれぞれの種の歴史と現在の地理的な分布の考察に基づいて,日本産陸棲哺乳類の種を7つのカテゴリーに分類することを提案している.これらのカテゴリーは明確に定義されているが,それぞれの種をどのカテゴリーに含めるかは,種の明確な系統分類学的位置と良好な化石記録を必要とする.本論文ではDobson(1994)の提唱したカテゴリーをOld Hondo Endemics, Expanding Hondo Endemics, Early Colonists, New Hondo Endemics, Late Colonists, Expanding Northern Endemicsの6つに整理し,多くの化石のデータを考慮に入れて,翼手目以外の日本産陸棲哺乳類の現生種をこれらのカテゴリーに区分することを試みた.いくつかの種の扱いはまだ試案の段階であるが,多くの主要な種についてはこれらの6つのカテゴリーに区分することができた.カテゴリーへの区分が不確実な種や,まだ区分ができない種については,その理由を示した.このように歴史的な内容によって性格づけられたカテゴリーへの区分によって,日本列島主要部の陸棲哺乳動物相の起源はより明確となり,生物地理に関する研究はよりダイナミックで歴史性の認識を明確にしたものになる.
著者
Kaori Nakanishi Makoto Nishida Tohru Ohama Toshiki Moriyama Keiko Yamauchi-Takihara
出版者
日本循環器学会
雑誌
Circulation Journal (ISSN:13469843)
巻号頁・発行日
pp.CJ-13-1134, (Released:2014-03-11)
参考文献数
33
被引用文献数
5 21

Background: Smoking and metabolic syndrome (MetS) are major public health problems in modern society and are important risk factors of cardiovascular disease (CVD). The association of smoking, MetS, and CVD is widely reported, but reports targeted to women are few. In the present study, we evaluated risk factors, including visceral fat area (VFA), for CVD and development of subclinical atherosclerosis in female smokers especially. Methods and Results: Subjects consisted of 162 apparent healthy female and male smokers, and 315 age-matched never-smokers who underwent a health examination in the Osaka University Health Care Center. For female smokers, lifestyle and carotid intima-media thickness (IMT) were evaluated. Triglycerides were significantly higher and high-density lipoprotein-cholesterol significantly lower in smokers than in never-smokers for both men and women. However, VFA was significantly high only in smoking women when compared with never-smokers. Multivariate analysis revealed that age, body mass index, and smoking were the independent predictors of high VFA in women. In addition, annual IMT increase was significantly higher in smokers than never-smokers in women. Conclusions: VFA was notably high in female smokers, but the difference was not observed in men. Smoking habit is an important risk factor of visceral fat accumulation and progression of subclinical atherosclerosis in women.
著者
保高 徹生 辻 英樹 今藤 好彦 鈴木 安和
出版者
公益社団法人 日本分析化学会
雑誌
分析化学 (ISSN:05251931)
巻号頁・発行日
vol.62, no.6, pp.499-506, 2013-06-05 (Released:2013-06-27)
参考文献数
15
被引用文献数
8 10

プルシアンブルー粒子担持不織布を充填したカートリッジに溶存態放射性セシウム(Cs)含有水を通水し,カートリッジに吸着させ,濃縮することにより,環境水中の溶存態放射性Cs濃度を迅速にモニタリングする技術を開発した.溶存態137Csの濃度を0.005~5 Bq L−1の範囲に調整した水を用いた試験の結果,通水速度が2.5 L min−1の場合,第1・第2カートリッジの137Csの回収率は20 L通水で90% 以上,100 L通水で83% 以上となった.また,通水速度を0.4 L min−1とした場合には,第1カートリッジの回収率が88% 以上に達した.本方法により,20 L濃縮を約10分,100 L濃縮を約50分で行うことが可能となる.また,ゲルマニウム半導体検出器の定量下限は20 L濃縮の4000秒測定で0.03 Bq L−1,100 L濃縮の43200秒測定で0.001~0.002 Bq L−1となり,従来法の前処理方法(20 Lで6時間以上)と比較して濃縮作業の迅速化が可能となる.
著者
永松 啓爾
出版者
耳鼻と臨床会
雑誌
耳鼻と臨床 (ISSN:04477227)
巻号頁・発行日
vol.34, no.6, pp.1568-1574, 1988-11-20 (Released:2013-05-10)
参考文献数
7

1 0 0 0 OA 巻頭言

著者
石橋 康正
出版者
日本ハンセン病学会
雑誌
日本ハンセン病学会雑誌 (ISSN:13423681)
巻号頁・発行日
vol.77, no.1, pp.1-2, 2008-02-01 (Released:2010-03-12)
著者
Kazuhiro Shiba
出版者
日本放射線安全管理学会
雑誌
Radiation Safety Management (ISSN:13471511)
巻号頁・発行日
vol.12, no.1, pp.31-36, 2013 (Released:2013-04-12)
参考文献数
2
被引用文献数
1 1

Huge amounts of radioactivity derived from the Fukushima nuclear accident were scattered in the atmosphere. Various kinds of vegetables in three prefectures in the Tohoku area were contaminated with 131I and 137Cs over the legal limit for shipment. A simple and effective removal method for contaminated farm products was developed to ensure the relief of farmers and the security of consumers. Distribution imaging of radioactivity in the contaminated vegetables, the physical removal of radioactivity from contaminated vegetables and the chemical removal of radioactivity from contaminated vegetables were examined. As a result, there were two types of vegetable contamination, spot type or spread type. The concentration of radioactivity was higher on the outer side than the inner side of a vegetable leaf. More than 80% of radioactivity attaches to the surface of leaves. Radioactivity removal by water washing showed no significant difference between boiling water and cold water. There was no significant difference between hand-washing and running water washing. The radioactivity of vegetables decreased by 70-80% for 131I and more than 80% for 137Cs by reducing agent treatments. In particular, ascorbic acid is promising as a safe and versatile option.
著者
Toshiyuki Masuzawa Yoshiyuki Uchishima Takashi Fukui Yoshihiro Okamoto Ming-Jeng Pan Teruki Kadosaka Nobuhiro Takada
出版者
国立感染症研究所 Japanese Journal of Infectious Diseases 編集委員会
雑誌
Japanese Journal of Infectious Diseases (ISSN:13446304)
巻号頁・発行日
vol.67, no.2, pp.111-114, 2014 (Released:2014-03-20)
参考文献数
23
被引用文献数
3 18

A total of 138 animals from 7 species (Apodemus agrarius, Bandicota indica, Crocidura suaveolens, Mus caroli, Mus formosanus, Rattus losea, and Suncus murinus) captured in Taichung, located in central Taiwan, and Kinmen Island, an island off the shore of China, were examined for the presence of Anaplasma phagocytophilum. The presence of the bacteria, which causes human granulocytic anaplasmosis, was examined by nested PCR targeting the16S rDNA. Twelve animals (8.7%) from M. caroli and R. losea, and 25 (18.1%) from A. agrarius, B. indica, M. caroli, and R. losea were infected with A. phagocytophilum and Anaplasma bovis, respectively. Phylogenetic analysis revealed that partial 16S rDNA sequences in the 12 aforementioned animals showed higher similarity to the sequences related to A. phagocytophilum detected in wild rodents (Rattus and Niviventer) from southeast China. The sequences of the other 25 animals belonged to the A. bovis clade. We demonstrated that small wild mammals were infected with A. phagocytophilum and A. bovis in Taichung and Kinmen Island, Taiwan.
著者
Ken Ohnishi Akihisa Takahashi Hiroaki Tanaka Takeo Ohnishi
出版者
日本宇宙生物科学会
雑誌
Biological Sciences in Space (ISSN:09149201)
巻号頁・発行日
vol.10, no.4, pp.247-251, 1996 (Released:2006-02-01)
参考文献数
4
被引用文献数
5 5

The catfish Synodontis nigriventris shows a unique habit taking a stable upsidedown posture in free water regardless of an above, one-sided illumination. This upsidedown posture can be observed when the catfish is apart from objects because the catfish usually orients its ventral side towards the water bottom or objects due to a so-called ventral substrate response. Thus, it is not easy to study the mechanism of the upside-down posture. To resolve this problem, the frequency of the upside-down posture was measured by using various sizes of vessel in which the catfish was kept. Video analysis showed that the frequency of the upside-down posture depended on the space size around the catfish. The smaller the size became, the higher the frequency of the upside-down posture became. Furthermore, the frequency of the upside-down posture depended on the shape of the vessel bottom. Curved-bottom vessels induced the upside-down posture more frequently than flat bottom. These findings suggest that a small, curved-bottom vessel is ideal for researching the upside-down postural control mechanism.
著者
高橋 元男
出版者
一般社団法人 日本数学会
雑誌
数学 (ISSN:0039470X)
巻号頁・発行日
vol.20, no.3, pp.129-141, 1968-08-20 (Released:2008-12-25)
参考文献数
23
著者
澤田 博光 志村 近史
出版者
一般社団法人 経営情報学会
雑誌
経営情報学会 全国研究発表大会要旨集 2011年春季全国研究発表大会
巻号頁・発行日
pp.50, 2011 (Released:2011-07-12)

日本企業のIT投資の効果は、業務改善によるコスト削減や経営管理の高度化の面ではある程度得られているが、経営環境への変化対応や新ビジネスの創出など価値創造の面では十分に得られていない。IT戦略が経営戦略を成功に導く大きな要素となっている企業では、今後の経営環境変化に対応してIT投資を行い、その効果を最大限に引き出すことが大きな課題である。企業は、経営戦略を実現するために大胆な企業改革と同時にIT導入を行うことで、大きなIT効果の効果を得ることができる。IT投資の効果を最大限に発揮している企業とは、ダイナミックな経営技術を展開する「価値認知」と柔軟かつ迅速な改革を可能なビジネス基盤といえる「業務組織化」に関する組織行動原理を有し、環境変化に柔軟に対応しつつ大胆な企業改革を行って、積極的に事業展開を進めている企業である。
著者
石井 正則
出版者
一般社団法人 日本めまい平衡医学会
雑誌
Equilibrium Research (ISSN:03855716)
巻号頁・発行日
vol.63, no.2, pp.67-80, 2004 (Released:2009-06-05)
参考文献数
36

Various factors are involved in the onset of motion sickness. As an investigation of one of those factors, the spatial orientation of experimental subjects was changed, and the relationship to the development of motion sickness was examined. For an objective study, it is necessary to establish an experimental model of motion sickness. Accordingly, artificial visual field information was created, and a computer capable of highspeed calculation was used to stimulate the experimental subjects with images undergoing temporal or spatial changes. Individual experimental subjects showed considerable variation in the development of motion sickness. Thus, it was important to perform the experiments on highly susceptible subjects. The results showed that, when for both time and space, the phase was asynchronized, motion sickness manifested at a high incidence. At the time motion sickness is manifested, there is always abnormal secretion of hypothalamus-pituitary-adrenal axis hormones and the development of symptoms of autonomic nervous system instability. For this reason, it can be surmised that there is involvement of emotions and the autonomic nervous system as a result of changes in spatial orientation. It can be thought that this is due to a state of asynchronization of the intrinsic information that leads to motor commands. In particular, information from an intrinsic model with unanticipated asynchronization of eye movement and head movement is important. The relationships among spatial orientation, head-eye movement, the memory process and emotion in the manifestation of motion sickness is discussed.
著者
池本 竜則 牛田 享宏 谷口 慎一郎 谷 俊一 森尾 一夫 佐々木 俊一 田中 茂樹
出版者
日本疼痛学会
雑誌
PAIN RESEARCH (ISSN:09158588)
巻号頁・発行日
vol.20, no.3, pp.111-115, 2005-08-26 (Released:2014-01-16)
参考文献数
9
被引用文献数
1 3

We employed the functional MRI (fMRI) to investigate the changes of brain activation after reducing of capsaicin-induced heat hyperalgesia. Eight healthy volunteers who have no history of brain vascular disease were enrolled in this study. Capsaicin-induced heat hyperalgesia was developed by topical application of 2% capsaicin cream to anterior surface of left forearm. First fMRI time series were taken an hour after the application of capsaicin and second fMRI time series were taken an hour after medication (Loxoprofen Na: 120 mg). As for the pain task, 45°C wet cotton was put on the region where the heat hyperalgesia was evoked by capsaicin cream. Results of first fMRI time series showed distinct activation in the thalamus, anterior cingulate cortex, supplementary motor area, and prefrontal cortex. An hour after medication, though heat hyperalgesia still remained, all participants reported improvement of pain discomfort (VAS 4.7 to 2.5). Second series fMRI showed activation only in the thalamus. These results suggest that deactivated areas (anterior cingulate, etc.) observed after medication might be involved mainly in the pain related discomfort.
著者
池本 竜則 牛田 享宏 谷口 慎一郎 谷 俊一 森尾 一夫 佐々木 俊一 田中 茂樹
出版者
日本疼痛学会
雑誌
PAIN RESEARCH (ISSN:09158588)
巻号頁・発行日
vol.21, no.3, pp.117-125, 2006-08-20 (Released:2013-10-24)
参考文献数
36
被引用文献数
2 1

Using functional magnetic resonance imaging (FMRI) technology, we investigated the difference of pain related brain cortical activation derived from noxious stimulation to the skin and muscular tissue. Ten healthy volunteers who have no history of brain vascular disease were enrolled in this study. A cutaneouos pain was provoked by isotonic (0.9%) saline injection into intradermal space on right lower leg through 24G plastic catheter, and a muscle pain was provoked by hypertonic (3%) saline injection into right tibialis anterior muscle. We used event-related FMRI to measure brain activity during each injection. Visual analogue scale (VAS) was used to quantify pain intensity and unpleasantness, and pain quality was assessed with several verbal descriptions. Results: Pain unpleasantness rating was higher in the muscle pain compared to the cutaneous pain,despite the same pain intensity rating. The cutaneous pain had more acute pain onset than the muscle pain. Pain duration after stimulation was short in the cutaneous pain, but long in the muscle pain. The extent of the painful region tended to be larger with the muscle pain, but there was no statistical significance. Evoked FMRI response from the cutaneous pain showed distinct brain activation in the inferior and superior parietal cortex (BA: Brodmann area 5/7/40), primary and secondary somatosensory cortex (S1 & S2), insula, supplementary motor area (SMA, BA6), posterior cingulate cortex and cerebellum. On the other hand, FMRI response from muscle pain showed distinct brain activation mainly in the contralateral insula. These results suggest that the parietal lobe including the S1 is the essential area for cognition of sharp and well-localized pain conditions such as cutaneous pain, and may not be essential for cognition of diffuse pain derived from muscular tissue.
著者
池本 竜則 牛田 享宏 谷口 慎一郎 谷 俊一 森尾 一夫 佐々木 俊一 Zinchuk Vadim 田中 茂樹
出版者
日本疼痛学会
雑誌
PAIN RESEARCH (ISSN:09158588)
巻号頁・発行日
vol.19, no.3, pp.107-112, 2004-07-31 (Released:2014-02-20)
参考文献数
9

It is widely known that sensation of the pain is derived from sensory-discriminative factor and emotional factor. Especially in chronic pain, emotional factors and psychosocial backgrounds are more likely to contribute for the patients' discomfort. The aim of this study is to investigate how emotional factor of pain participates in intractable pain. We employed fMRI to compare the brain activations occurring in the orthopaedic neuropathic pain patients with allodynia and normal individuals in response to the visual virtual painful experience. During fMRI scanning, a video demonstrating an actual tactile stimulation of the palm and its imitation were shown to participants. In contrast to normal individuals,allodynia patients also displayed activation of the areas reflecting emotions: frontal lobe and anterior cingulate. These findings suggest that brain have important role in the development and maintaining of peripheral originated chronic painful condition.
著者
木村 百合香 加藤 智史 高橋 正時 岸本 誠司
出版者
特定非営利活動法人 日本気管食道科学会
雑誌
日本気管食道科学会会報 (ISSN:00290645)
巻号頁・発行日
vol.59, no.6, pp.551-555, 2008-12-10 (Released:2008-12-25)
参考文献数
12
被引用文献数
1

今回われわれはアンギオテンシンII受容体拮抗薬(ARB)投与と血管再生治療後に生じた喉頭浮腫治療後,nasogastric tube症候群による両側声帯麻痺を発症した1例を報告した。症例は76歳男性,主訴は吸気時呼吸困難であり,喉頭内視鏡検査にて著明な喉頭浮腫を認めたため同日緊急気管切開術を施行した。3カ月前より高血圧に対しARBであるカンデサルタンシレキセチル(ブロプレス®)を使用し,また閉塞性動脈硬化症に対し末梢血幹細胞移植による血管再生治療後7日目であった。喉頭浮腫の改善後,両側声帯正中固定が明らかとなった。多系統萎縮症等は否定的であり,経鼻胃管を挿入中であったことからnasogastric tube症候群による両側声帯麻痺と診断した。発症後10カ月現在も両声帯は正中位固定のままカニューレ抜去困難状態が続いている。アンギオテンシン変換酵素阻害剤とARBの重要な副作用に血管性浮腫があり,時に重篤な気道狭窄をきたすことがある一方,再生医療のさきがけとして血管再生治療が臨床導入されているが,移植された幹細胞から放出されるサイトカインにより血管性浮腫をきたす可能性も指摘されており,両者が本症例の喉頭浮腫に関与したものと考えた。また,経鼻胃管の留置による重篤な合併症であるnasogastric tube症候群にも留意が必要である。
著者
薗田 直志 長田 哲次 内山 佳之 田中 秀生 増本 一真 橋本 賢二
出版者
社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.56, no.1, pp.36-39, 2010-01-20 (Released:2013-10-19)
参考文献数
31
被引用文献数
4

Angioedema is sudden local swelling of the lips, eyelids, buccal region and tongue. It is usually induced by drugs. Angioedema is a well-recognized side effect of angiotensin-converting enzyme inhibitors (ACEs), but angioedema associated angiotensin II receptors blockers (ARBs) is very rare. We report a case of angioedema of the tongue and floor of the mouth that was probably induced by an ARB.A 76-year-old man came to our emergency unit because of acute swelling of the tongue and difficulty breathing.He had a medical history of hypertension and cerebral infarction, but no allergic disease. He had severe diffuse edematous swelling of the submandibular and cervical regions, an elevated tongue making it difficult to close his mouth, and sialorrhea.Although urgent computed tomography showed marked swelling of the tongue, there was no evidence of edema in the respiratory tract. Angioedema of the tongue was diagnosed, and hydrocortisone sodium succinate was given intravenously. Within 12 hours the swelling of the tongue and floor of the mouth resolved completely.Candesartan was strongly suspected to have caused the angioedema, and we discontinued it. There has been no evidence of recurrence of the angioedema during the 18 months since candesartan was discontinued.