著者
林 博通
出版者
日本考古学会
雑誌
考古学雑誌 (ISSN:00038075)
巻号頁・発行日
vol.67, no.4, pp.p502-516, 1982-03
著者
林 昌洋
出版者
一般社団法人 日本臓器保存生物医学会
雑誌
Organ Biology (ISSN:13405152)
巻号頁・発行日
vol.18, no.3, pp.279-286, 2011-12-10 (Released:2014-11-26)
参考文献数
17

While careful consideration to avoid a second scourge like thalidomide is required, disadvantages for mothers and fetuses by restraint of necessary drug prescription because of too much concern about the effects on fetuses must be avoided. Information sources to evaluate teratogenicity of drugs themselves include epidemiological investigations, case reports, and animal reproduction studies and are considered more reliable in this order. And breast milk is the best source of nutrition and it also serves as a source of substances providing immunity for a newborn infant. However, there are times when nursing mothers may have to take some kind of medication, so it is necessary to evaluate the effect of drugs that are transferred to infants through breast milk, and to select medications with minimal adverse effects.
著者
武田 泰明 金崎 益巳 加納 尚之 井上 倫夫 小林 康浩
雑誌
全国大会講演論文集
巻号頁・発行日
vol.第45回, no.ハードウェア, pp.89-90, 1992-09-28

我々の研究室では,共有メモリ型マルチプロセッサシステムのプロトタイプとして,プロセッサユニット(PU)を64台実装した並列計算機"砂丘"を製作した.このタイプの計算機では,アクセス競合によるオーバーヘッドはシステムが大規模になるほど増え,PUの台数に比例した処理速度の向上が得られなくなる.アクセス競合を回避するために,共有メモリの階層化,インターリーブ方式,多重ポート化を行った.さらにメインメモリは,マルチリードワンライト方式を採用し,リードアクセスバスとライトアクセスバスを分離した.本報告では,並列計算機"砂丘"のシステム構成について述べる.
著者
増田 雄樹 横山 哲也 岡林 識起 石川 晃
雑誌
JpGU-AGU Joint Meeting 2020
巻号頁・発行日
2020-03-13

Micro-scale isotopic analysis of geologic materials is getting more important in recent geochemistry. Although in-situ isotopic measurements with LA-ICP-MS or SIMS have played a central role in geochemical applications, these techniques are not necessarily suitable for isotopic analysis that requires chemical separation prior to mass spectrometry. In such cases, sampling with micro milling [1] or Laser Ablation in Liquid (LAL) [2] has been applied. However, these sampling techniques could cause cross contamination from the micro-drill material, relatively low recovery yield, and longer sampling time.To overcome these problems, we developed the Laser Ablation with Filter (LAF) method in which sample particles ablated by a fs-laser (IFRIT, Cyber Laser) are carried via the flow of He gas in a Teflon tube and then caught by a membrane filter (pore size: 0.1 µm). The performance of the LAF method was evaluated by using a glass standard (NIST SRM 610), which was ablated by a spiral analysis mode with a fluence of 28 J cm-2, repetition rate of 500 Hz, pulse lengths of 240 fs, wavelength of 260 nm, and raster speed of 100 µm/s. The typical pit size was 20 µm in width and 20 µm deep, which required 1.4 h for sampling an area of 1×1×0.1 mm3. The sample particles retrieved by the filter were dissolved by a mixture of HF and HNO3, then treated with HClO4 to decompose insoluble fluoride precipitates. The sample solution was split into two aliquots; one dedicated for the analysis of trace element abundances with ICP-MS (Xseries 2, Thermo) and the other for isotopic analysis with TIMS (TRITON plus, Thermo) after chemical separation. We found that the recovery yields of trace elements ranged from 80-90%, in which the effect of elemental fluctuation was suppressed owing to the use of the fs-laser [2, 3]. The 87Sr/86Sr of NIST 610 collected by the LAF method was 0.7096787 ± 0.0000016 (2SE), which is consistent with that for NIST 610 (87Sr/86Sr = 0.7096779 ± 0.0000028) separately measured by dissolving a piece of the glass standard. The procedural blank of the LAF method was negligible to perform the trace element and isotopic analyses. The new method can be applied to small minerals and inclusions in terrestrial rocks and meteorites for understanding the carrier phases that cause isotope heterogeneities in mantle rocks and refractory inclusions in carbonaceous chondrites.[1]Myojo, K. et al. (2018) Astrophys. J. 853, 48. [2]Okabayashi, S. et al. (2011) J. Anal. At. Spectrom, 26, 1393-1400. [3]Fernández B. et al. (2007) TrAC. 26, 951–966.
著者
小林 和男
出版者
創造
雑誌
プロメテウス (ISSN:03862828)
巻号頁・発行日
vol.10, no.4, pp.p25-28, 1986-07
著者
佐藤 宏昭 中村 一 本庄 巖 藤田 明彦 高橋 晴雄 林 正彦
出版者
耳鼻咽喉科臨床学会
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.81, no.9, pp.1383-1387, 1988-09-01 (Released:2011-11-04)
参考文献数
10
被引用文献数
2 7

The clinical usefulness of Tsumura-Saireito, which was judged by tympanoaudiometric tests, was compared with that of cepharanthin in 64 ears of 42 children with otitis media with effusion. The trial was a randomized controlled study.The efficacy rate for the 32 ears treated with Tsumura-Saireito was 43.8% and that for the 32 ears treated with Cepharanthin was 18.8%; the difference was significant (p<0.05). No side effects were observed in either group.These results indicate that Tsumura-Saireito is more effective in children with otitis media with effusion than Cepharanthin.
著者
林 伊吹 林 与志子 宇野 功 藤原 裕樹 高橋 宏明
出版者
耳鼻と臨床会
雑誌
耳鼻と臨床 (ISSN:04477227)
巻号頁・発行日
vol.43, no.5, pp.666-672, 1997-09-20 (Released:2013-05-10)
参考文献数
10
被引用文献数
3

嚥下を観察する際, 嚥下開始の指標を決定するために, 舌骨上筋群表面筋電図を用いることが多い. これは, 被験者に非侵襲的であるため, 有用な方法とされている. しかし, 舌骨上筋群表面筋電図と実際の筋の活動とが, どのように関わつているかを確認する必要がある. 著者らは甲状舌骨筋とオトガイ舌骨筋に電極を刺入して得た筋電図と, 舌骨上筋群表面筋電図を同時記録し比較検討した.嚥下の際に, 舌骨上筋群表面筋電図波形上, 2つの波形変化を認めた. 最初におこる小さい振れと, それに続く大きい振れである. 前者をEMG1, 後者をEMG2とした. 筋電図の比較により, EMG1はオトガイ舌骨筋の活動開始点と, EMG2は甲状舌骨筋の活動開始点と強い相関を認めた.この結果より, 舌骨上筋群表面筋電図は嚥下開始の指標を決定でき, EMG1は嚥下第一期の開始を, EMG2は嚥下第二期の開始の指標を表すものと考えられた.
著者
吉原 良祐 八幡 知之 栗林 繁樹 花川 公麿 大西 正孝 大林 良和 清水 伸一 謝 詔銘 松田 洋三
出版者
一般社団法人 日本感染症学会
雑誌
感染症学雑誌 (ISSN:03875911)
巻号頁・発行日
vol.65, no.1, pp.119-123, 1991-01-20 (Released:2011-09-07)
参考文献数
15

A 58-year-old female was introduced to our hospital for admission on April 22, 1988, because of high grade fever and agranulocytosis. She had eschers on her left zygomatic region and medial region of the right thigh. The latter lesion was accompanied by cellulitis. Laboratory tests showed her WBC was 600/mm3 and T-Bil was 6.51 mg/dl. By using minocyclin, piperacillin and other drugs, her general condition and laboratory data became better in a few days.Although her skin lesions resembled “Tsutsugamushi disease”, serological tests showed no evidence for Rickettia infection. So we could not rule out that another kind of insect bite may also develop such a severe clinical course. Furthermore, Staphylococcus aureus or Clostridium spp., which were detected in her pus, might have the toxic effects of inducing agranulocytosis, which might mainly be the result from the local WBC emigration, and jaundice, just like the effects of the endotoxin of Gram negative bacteria.
著者
前田 恵利 河野 美穂 小川 千尋 大場 亜紀 高林 康江 藤井 美香 原本 久美子 日野 徳子 今野 理恵 堀尾 強
出版者
関西国際大学
雑誌
研究紀要 (ISSN:13455311)
巻号頁・発行日
no.19, pp.101-110, 2018-03-10

In this study, assistance for improving urinary incontinence based on bladder function evaluation was practically applied to four patients with voiding dysfunction. Analysis was then performed on actual verbal communication incorporating prompted voiding (PV) that was found to effectively motivate patients during assistance.Effective verbal communication fell into three categories: verbal communication of joy in expressing a desire to void and appreciation; verbal confirmation of recovery in urinary function and verbal praise; and verbal communication that respects behavior and pace during voiding. Voiding assistance based on bladder function evaluation and communication incorporating PV led to patients voluntarily asserting their desire to void and thereby to improvements in urinary incontinence. The findings suggest that in the course of improving voiding function, emphasizing respect for patients’ self-esteem in verbal communication is as important as adopting an individualized approach to voiding assistance during bladder training.