著者
小林 悟
出版者
筑波大学
雑誌
基盤研究(A)
巻号頁・発行日
2012-04-01

本研究は、生殖細胞系列の性決定機構を解明することを目的としている。これまでに、始原生殖細胞中において細胞自律的にメス化を誘導できるSxlに制御される候補遺伝子を同定するとともに、始原生殖細胞の性差に依存して発現する遺伝子の網羅的な同定、中胚葉を持たない原始的な動物であるヒドラにおいて、生殖幹細胞の性差に依存して発現する遺伝子の網羅的な同定を行うことに成功した。以上の成果は、生殖細胞系列における普遍的な性決定機構を明らかにする上での基盤となる。
著者
廣垣 俊樹 青山 栄一 杉浦 義久 小林 飛翔
出版者
一般社団法人 日本機械学会
雑誌
日本機械学会論文集 (ISSN:21879761)
巻号頁・発行日
vol.83, no.855, pp.17-00132-17-00132, 2017 (Released:2017-11-25)
参考文献数
14
被引用文献数
3

The purpose of this study is to construct the automation technology based on the hammering task and its sound feedback with an industrial humanoid robot equipped with an integrated system of vision, sound and dual arm motion. First, we discuss a suitable flexible rubber stick to achieve the hammering task and developed the acoustic recognition system based on its hit sounds. Second, we confirm that the developed system is sufficient to investigate the task playing the glockenspiel, and also discuss the characteristics of motion based on dual arm motion. Third, we attempt to cooperate with hammering the bottle and pouring liquid into it based on estimating its hit sound. As a result, it can be seen that the proposed system using an industrial humanoid robot achieves sufficient motion accuracy. Therefore it is demonstrated that the proposed approach is found to be effective to construct the automation technology based on the hammering task and its sound feedback with an industrial humanoid robot.
著者
寺町 ひとみ 杉田 郁人 伊野 陽子 林 勇汰 吉田 阿希 大坪 愛実 上野 杏莉 勝野 隼人 野口 義紘 井口 和弘 舘 知也
出版者
公益社団法人 日本薬学会
雑誌
YAKUGAKU ZASSHI (ISSN:00316903)
巻号頁・発行日
vol.137, no.9, pp.1177-1184, 2017 (Released:2017-09-01)
参考文献数
21
被引用文献数
4

We analyzed impression data and the scale of communication skills of students using text mining method to clarify which area a student was conscious of in communication in practical training. The results revealed that students tended to be conscious of the difference between practical hospital training and practical pharmacy training. In practical hospital training, specific expressions denoting relationships were “patient-visit”, “counseling-conduct”, “patient-counseling”, and “patient-talk”. In practical pharmacy training, specific expressions denoting relationships were “patient counseling-conduct”, “story-listen”, “patient-many”, and “patient-visit”. In practical hospital training, the word “patient” was connected to many words suggesting that students were conscious of a patient-centered communication. In practical pharmacy training, words such as “patient counseling”, “patient”, and “explanation” were placed in center and connected with many other words and there was an independent relationship between “communication” and “accept”. In conclusion, it was suggested that students attempted active patient-centered communication in practical hospital training, while they were conscious of listening closely in patient counseling in practical pharmacy training.
著者
林田 志峯 獨協医科大学産科婦人科学
雑誌
Dokkyo journal of medical sciences (ISSN:03855023)
巻号頁・発行日
vol.37, no.1, pp.T49-T56, 2010-03-25
被引用文献数
1

わが国におけるB 型肝炎ウイルス(HBV)母子感染予防法として厚生省方式(HB ワクチン生後二ヶ月開始,HBIG2回投与)が広く実施されてきた.同時期に開発された千葉大方式(HB ワクチン生後24時間内開始,HBIG1回投与)の多施設共同臨床治験により,同方式と厚生省方式間で児の能動免疫獲得率・キャリア化率,有害事象発生率に関して有意差が無く,省力化・安全性・経済性の観点から千葉大方式の優位性が報告されている.今回,HBV 母子感染予防対策を児のHBV キャリア化阻止と対策漏れにエンドポイントを絞り,千葉大方式を更に簡略化し,全ての処置を生後1 ヶ月健診時に完了する獨協医大方式(HB ワクチン生後24時間以内開始,HBIG1回投与)の臨床治験を日本および中国大連市において実施した.両方式群間で,児の能動免疫獲得率,生後6 ヶ月時獲得HBs 抗体価,キャリア化率,有害事象発生率の全てにおいて有意差を認めず,一方,省力化・経済性と対策漏れに関しては獨協医大方式の優位性が判明した.獨協医大方式はその経済性,簡便性より,わが国はもとよりHBV 侵淫地域であるアフリカ,東南アジア諸国等においても積極的採用が期待され得る選択肢である.
著者
寺林 敏 藤原 一哉 山下 智史 並木 隆和 SATOSHI TERABAYASHI KAZUYA FUJIWARA TOMOFUMI YAMASHITA TAKAKAZU NAMIKI 京都府立大学農学部蔬菜園芸学研究室 京都府立大学農学部蔬菜園芸学研究室 京都府立大学農学部蔬菜園芸学研究室 京都府立大学農学部蔬菜園芸学研究室 Laboratory of Olericulture Faculty of Agriculture Kyoto Prefectural University Laboratory of Olericulture Faculty of Agriculture Kyoto Prefectural University Laboratory of Olericulture Faculty of Agriculture Kyoto Prefectural University Laboratory of Olericulture Faculty of Agriculture Kyoto Prefectural University
雑誌
京都府立大學學術報告. 農學 = The scientific reports of Kyoto Prefectural University. Agriculture (ISSN:00757373)
巻号頁・発行日
vol.37, pp.183-188, 1985-11-15

トマト(Lycopersicon csculentum MILL cv. Ohgata-fukujyu)を水耕および土耕栽培し, 果実の果皮強度, 果皮の厚さ, 果肉強度を測定した。水耕区, 土耕区とも施肥濃度が高いほど, 果皮強度が高く, 果皮の厚さが増した。一方, 果肉強度は低下した。果実の成熟段階が進んだものほど, 果皮強度は低かった。収穫後30℃暗黒条件下で6日間ないし8日間貯蔵した場合, 果皮強度の低下は小さく, 果肉強度の低下が大きかった。とくに土耕区のトマトで顕著であった。果実の硬さを支配する果皮強度や果肉強度の要因は, 施肥濃度, 果房段位, 果実の成熟段階, 収穫後の日数によって変化した。しかし, これらの要因は水耕および土耕といった栽培法の違いによって特徴づけられるものでなかった。
著者
西村 沙矢香 宮林 沙季 瀧井 幸男
出版者
日本食生活学会
雑誌
日本食生活学会誌 (ISSN:13469770)
巻号頁・発行日
vol.21, no.3, pp.217-221, 2010-12-30 (Released:2011-01-24)
参考文献数
17
被引用文献数
1 1

This research studied the eating behavior and genetic factors that cause masked obesity, in which body fat percentage is high even though the body weight is low or normal, a phenomenon that is increasing among young Japanese women. This study performed physical measurement, an eating-behavior survey based on EAT-26, and a genetic polymorphism test that used the non-invasive collection of fingernail clippings on 94 young women. The result showed that 13. 8% of the women have masked obesity, while 39. 4% have masked obesity tendency, and the total of both groups equaled more than half the total number (53. 2%). When the masked obesity group is compared to the standard group, no difference can be seen in the frequency of appearance of β3-adrenergic receptor (β3AR) genetic polymorphism (Trp64Arg) and insulin-induced gene 2 (INSIG2) genetic polymorphism (rs7566605), but there is a significantly higher rating in EAT-26. These results suggest the possibility that unique eating behavior habits of young women are largely involved in causing masked obesity in this population.
著者
松下見林
巻号頁・発行日
vol.[1], 1665
著者
矢野 隆 小林 朝人
出版者
一般社団法人 日本建築学会
雑誌
日本建築学会計画系論文報告集 (ISSN:09108017)
巻号頁・発行日
vol.354, pp.1-10, 1985-08-30 (Released:2017-12-25)

A laboratory study was carried out to investigate disturbance and noisiness of periodically non-steady noises in four task conditions. Totally 326 subjects participated in experiments. There were two main variables : the range of level fluctuation was from 0 to 40 dB and the repetition rate varied from 0. 25 to 4 Hz. The noises were exposed at two levels, 60 and 70dB L_<eq>. Task conditions were articulation test, intelligibility test, calculation, and reading, and their exposure durations were respectively about 6, 8, 3, 2.5 minutes. The task performance was investigated and the relation between disturbance or noisiness and performance was also discussed. The conclusions are summarized as follows. 1) In task conditions in which task performance is significantly affected by noises, disturbance and noisiness are influenced considerably by performance and have high correlation with it. 2) In task conditions in which task performance is not significantly affected by noises, disturbance and noisiness increase with range of level fluctuation. 3) In the same conditions as 2), the effect of repetition rate was not reasonably found, but consistently disturbance or noisiness tends to rise at 1 Hz in the case of triangular noises and drop at 1 Hz in rectangular noises. 4) It is considered that the complex effect of repetition rate as mentioned above is contributed by the interference of concentration on task and the rhythm of task exept for the effect of fluctuation factors.
著者
林 眞琴
出版者
公益社団法人 日本材料学会
雑誌
材料 (ISSN:05145163)
巻号頁・発行日
vol.46, no.4, pp.432-437, 1997-04-15 (Released:2009-06-03)
参考文献数
7
被引用文献数
4 4

The effect of fluctuating stress on the fatigue strength of type 304 stainless steel in air at 288°C was examined. In any of the 2 step increasing stress, 2 step decreasing stress, repeated 2 step stress (high to low), repeated 2 step stress (low to high) and gradual increasing stress, the cumulative usage factor calculated based on the linear damage law exceeds 1. In the 2 step increasing or decreasing stress, the usage factor for the decreasing stress type is larger than the increasing stress type. On the other hand, the cummulative usage factor for the repeated 2 step stress (low to high) is larger than the repeated 2 step stress (high to law), and the usage factor increases with increasing number of cycles at the first stress. The smaller the difference between the first stress and the second stress, the larger the usage factor. In the gradual increasing stress, the usage factor increases with increasing number of cycles at each stress.
著者
山口 賀大 佐久間 重光 遠渡 将輝 坂口 晃平 田口 慧 小林 里奈 足立 充 伊藤 裕 田口 望 日比 英晴
出版者
一般社団法人 日本顎関節学会
雑誌
日本顎関節学会雑誌 (ISSN:09153004)
巻号頁・発行日
vol.28, no.2, pp.126-134, 2016-08-20 (Released:2016-10-14)
参考文献数
34

運動療法は,施術直後より関節可動域を増大し,疼痛を早期に軽減させ病悩期間を短縮するものの,その効果について定量的な評価を行った研究は少ない。本研究では,術者が行う顎関節可動化療法と患者が行う自己牽引療法を1つの運動療法プログラムとして捉え,非復位性関節円板前方転位症例に実施した際の短期的治療効果を検討した。顎関節機能に中等度以上の障害が認められた45例を対象として運動療法を施行し,初診時とその約2週間後の初回再来時における臨床症状(最大開口域,安静時痛,開閉口時痛,咀嚼時痛および日常生活支障度)について評価した。その結果,最大開口域,開閉口時痛,咀嚼時痛および日常生活支障度において有意な改善を認めた(p<0.001)。これら症状の改善は,運動療法により関節可動域が改善され,関節腔が拡大されることで下顎頭の動きが改善したものと考える。したがって,本運動療法プログラムは,非復位性関節円板前方転位に伴う諸症状を短期間に軽減させる有効な保存療法になる可能性が示唆された。
著者
松本 哲一 小林 武彦
出版者
特定非営利活動法人 日本火山学会
雑誌
火山 (ISSN:04534360)
巻号頁・発行日
vol.44, no.1, pp.1-12, 1999-03-05 (Released:2017-03-20)
参考文献数
12
被引用文献数
4

A systematic K-Ar age determination has been made on thirty-seven samples from the Older Ontake volcanic products, Ontake Volcano, central Japan, with analytical uncertainties mostly within ±5% (1σ level). The “Kuragoehara Lava”, which the previous researchers used as a key bed for stratigraphic correlation, gives significantly different eruption ages in each disthbution area, and some lavas classified into the same stratigraphic units among each area also show quite diffrent K-Ar ages. Hence, a revised volcano-stratigraphy is proposed based on the radiometric data obtained in the present study. The Older Ontake Volcano may be a compound volcano consisting of more than four stratovolcanoes with different vents. The first one, “;Tobu Volcano Group”, erupted at around 750-650 ka on the wide eastern side. The second one, “Tsuchiurazawa Volcano”, erupted at around 680-570 ka mainly in the western area. The third one, “Uetawarayama Volcano”, produced lavas at around 540-520 ka, and the products filled along valleys in the western area. The last one, “Mikasayama Volcano” erupted at around 440-420 ka in the southeastern area. The inactive period between the Older and Younger Ontake volcanic products continued for more than three hundred thousand years. The present study has revealed that the K-Ar age determination is effective for estimating a time gap between the Quatermary volcanic products whose stratigraphic relation can not be well defined in field.