著者

by the editors of Time-Life Books with text by Benjamin Capps

出版者

Time-Life Books

巻号頁・発行日

1973

著者

written in High-Dutch by Engelbertus Kæmpfer and translated from his original manuscript never before printed by J.G. Scheuchzer with the life of the author and an introduction

出版者

Printed for the translator

巻号頁・発行日

1727

著者

Nozomi SHIWA Hiroko YAMASHITA Koki TOMIOKA Kazunori KIMITSUKI Daria Llenaresas MANALO Satoshi INOUE Chun-Ho PARK

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.18-0591, (Released:2018-12-07)

被引用文献数

3

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In the present study, follicle-sinus complexes (FSCs) were harvested from the muzzle skin of 123 dogs with suspected canine rabies, and the sensitivity and specificity of FSC analysis were compared with those of brain tissue immunohistochemistry analysis. In the FSCs, viral antigen was detected from Merkel cells. Sensitivity was 97.3%, specificity was 100%, and the coefficient κ was 0.88. These results reconfirm that FSCs are very useful for the postmortem diagnosis of canine rabies, and suggest that 5 FSCs can yield results that are almost equivalent to those derived from brain tissue analysis in rabid dogs.

著者

阿川 佐和子 ベジャ-ル モ-リス

出版者

文芸春秋

雑誌

週刊文春

巻号頁・発行日

vol.40, no.28, pp.52-56, 1998-07-23

著者

Pawel Szulc Ez Zoubir Amri Annie Varennes Patricia Panaia-Ferrari Eric Fontas Joëlle Goudable Roland Chapurlat Véronique Breuil

出版者

The Japanese Circulation Society

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

vol.82, no.12, pp.2954-2961, 2018-11-24 (Released:2018-11-24)

参考文献数

42

被引用文献数

7

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Background: Severe abdominal aortic calcification (AAC) points to high cardiovascular risk and leptin stimulates arterial calcification; however, clinical data on their association are scarce. We studied the link between serum leptin and AAC severity and progression, and the effect of smoking and lipid levels, on this association in men. Methods and Results: At baseline, 548 community-dwelling men aged 50–85 years underwent blood collection and lateral lumbar spine radiography. In 448 men, X-ray was repeated after 3 and 7.5 years. AAC was assessed using Kauppila’s semiquantitative score. In multivariable models, high leptin was associated with higher odds of severe AAC (odds ratio [OR]=1.71 per SD, 95% confidence interval [CI]: 1.22–2.40). The odds of severe AAC were the highest in men who had elevated leptin levels and either were ever-smokers (OR=9.22, 95% CI: 3.43–24.78) or had hypertriglyceridemia (vs. men without these characteristics). Higher leptin was associated with greater AAC progression (OR=1.34 per SD, 95% CI: 1.04–1.74). The risk of AAC progression was the highest in men who had elevated leptin levels and either were current smokers or had high low-density lipoprotein-cholesterol levels (OR=5.91, 95% CI: 2.46–14.16 vs. men without these characteristics). These links remained significant after adjustment for baseline AAC and in subgroups defined according to smoking and low-density lipoprotein-cholesterol levels. Conclusions: In older men, high leptin levels are associated with greater severity and rapid progression of AAC independent of smoking, low-density lipoprotein-cholesterol or triglycerides.

著者

Evelyn Villanueva Nozomi Fujibayashi-Yoshii Suguru Matsuzaki Kazuki Yamazaki Chairat Burana Kenji Yamane

出版者

The Japanese Society for Horticultural Science

雑誌

The Horticulture Journal (ISSN:21890102)

巻号頁・発行日

pp.UTD-031, (Released:2018-12-07)

被引用文献数

7

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The postharvest physiology of cut astilbe inflorescences (Astilbe × arendsii), which consist of many small florets with a short vase life, was studied in response to treatments to extend their vase life. Exogenous ethylene treatment at 0.3 μL·L−1 for 7 h did not affect the senescence of inflorescences or leaves of five cultivars and 0.2 mM silver thiosulfate for 2 h did not improve the quality of inflorescences of three cultivars, which indicated that ethylene is not a critical factor for senescence in astilbe florets. Continuous treatment with 2% sucrose or 2% trehalose solutions prolonged the cut inflorescence vase life of one or two of five astilbe cultivars, respectively. Pulse treatment with 2% trehalose in combination with 6% sucrose increased total soluble sugar contents from 11.4 to 57.6 mg·g−1 FW and raised the respiration rate of inflorescences from 15.3 to 28.4 μmol CO2·h−1·g−1 FW at 2 days after harvest (DAH) in the cultivar ‘Gloria Purpurea’. However, the effects of pulse treatment diminished at 4 DAH and extended the vase life from 4.0 days to a maximum of 5.6 days, which suggested that pulse treatments were inadequate to maintain sugar contents and respiration activity. Continuous treatment with 6% sucrose extended the vase life from 4.3 to 10.0 days and raised the chroma (C*) value of florets from 28.7 to 54.9 at 8 DAH. Continuous treatment with 2% trehalase + 4% sucrose markedly prolonged the vase life to 11.5 days and increased the C* value to 53.9 at 8 DAH. Under stereomicroscopic observation, continuous treatment with 2% trehalase + 4% sucrose maintained more vivid pink color of petals, styles, filaments and receptacles than those in control florets at 9 DAH. Combined treatment with 2% trehalose and 30 μM validamycin A, a potent inhibitor of trehalose metabolizing activity, induced severe wilting of florets and necrotic spots on leaves. Exogenous trehalose may be hydrolyzed by trehalose metabolizing activity in cut astilbe inflorescences. The results suggest that continuous treatment with trehalose and sucrose solutions is effective to maintain development and delay senescence of florets to extend the vase life of cut astilbe inflorescences.

著者

竹原 真美 本吉 洋一 堀江 憲路 外田 智千 馬場 壮太郎 亀井 淳志 北野 一平 Nantasin Prayath Setiawan Nugroho Dashbaatar Davaa-ochir

出版者

一般社団法人日本地球化学会

雑誌

日本地球化学会年会要旨集

巻号頁・発行日

vol.65, 2018

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<p>ジルコンは物理化学的に安定な鉱物であるとされる.一方,超高温変成作用(1000℃以上)によって,ジルコン結晶中のPbの二次的な移動が起こり,年代値等に影響を与えるという例も報告されている.そこで,ジルコン結晶中のPb及びその他微量元素の(超)高温環境下における挙動について検証するため,超高温変成作用の痕跡を残す東南極ナピア岩体に着目し,本岩体の露岩であるハーベイヌナタークに産する斜方輝石珪長質片麻岩中のジルコンを対象として,高感度高分解能イオンマイクロプローブ(SHRIMP-IIe)によるU-Pb年代測定及びZrと微量元素(Hf, Ti, P, REE, Ca, Mn, Fe, Al, Mg, K, Li, B, F, Cl)組成分析を行った.</p>

著者

大辺 理恵 新谷 俊裕 Paludan-Muller Martin

出版者

大阪大学言語文化研究科言語社会専攻デンマーク語・スウェーデン語研究室

雑誌

IDUN : journal of Nordic studies : 北欧研究 (ISSN:02879042)

巻号頁・発行日

no.21, pp.97-159, 2014

著者

edited by Tikva Frymer-Kensky ...

出版者

Westview Press

巻号頁・発行日

2000

著者

edited by Martin L. Davies and Claus-Christian W. Szejnmann

出版者

Palgrave Macmillian

巻号頁・発行日

2007

著者

Seo Eun-Seong Kandra Lili Gyémánt Gyöngyi Janecek Štefan Haser Richard Aghajari Nushin Hachem Maher Abou Svensson Birte Andersen Joakim M. Nielsen Morten M. Vester-Christensen Malene B. Christiansen Camilla Jensen Johanne M. Mótyán Janos A. Glaring Mikkel A. Blennow Andreas

出版者

日本応用糖質科学会

雑誌

Journal of Applied Glycoscience (ISSN:13447882)

巻号頁・発行日

vol.57, no.2, pp.157-162, 2010

被引用文献数

3

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Two carbohydrate binding surface sites (SBSs) on barley &alpha;-amylase 1 (AMY1) of glycoside hydrolase family 13 (GH13) displayed synergy in interactions with starch granules, thus being pivotal for hydrolysis of supramolecular substrates. Mutational analysis showed that SBS1 is more critical for the conversion of starch granules, while SBS2 has higher affinity than SBS1 for &beta;-cyclodextrin (&beta;-CD). Noticeably, the binding preference of &beta;-CD to SBS2 differed distinctly from that of maltooligosaccharides to the catalytic nucleophile mutant D180A AMY1. Binding energy maps at subsites -8 through +4 of the active site indicated remarkably elevated affinity due to the Y380A mutation at SBS2. The high-yield AMY2 expression variant A42P, made it possible to show that Tyr378&mdash;corresponding to Tyr380 in AMY1&mdash;has a role in interactions with starch granules, but not in &beta;-CD binding. Besides SBSs, dedicated starch binding domains (SBDs) mediate binding to starch granules. SBDs are currently categorised into 9 carbohydrate binding module (CBM) families. A novel CBM20 subfamily encountered in regulatory enzymes possesses characteristically low affinity for &beta;-CD. Although &alpha;-amylase is essential for starch mobilisation in germinating barley seeds, efficient degradation requires the concerted action of &alpha;-amylase, &beta;-amylase, limit dextrinase (LD) and possibly &alpha;-glucosidase. Limit dextrinase (LD) is encoded by a single gene and represents the sole debranching activity during germination. Recent expression of functional LD in <i>Pichia pastoris</i> makes biochemical and biophysical characterisation of this GH13 enzyme possible. An endogenous limit dextrinase inhibitor was cloned and produced recombinantly and demonstrated to have sub-nanomolar affinity for LD.

著者

Kim Yoon Shim Won Park Byung-Gook

出版者

Institute of Physics

雑誌

Jpn. J. Appl. Phys. (ISSN:00214922)

巻号頁・発行日

vol.54, no.6, 2015-05-26

被引用文献数

2

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In this paper, we report the fabrication and analysis of the gated twin-bit NAND flash memory with a nitride charge-trapping layer. This device is based on the recessed channel structure, and it has an additional cut-off gate that enables 2-bit operation. Therefore, the density of the array can be doubled without any difficulty in patterning. The fabrication method for gated twin-bit (GTB) silicon–oxide–nitride–oxide–silicon (SONOS) memories and their electrical characteristics are described in this paper. Program/erase characteristics are observed and the 2-bit operation is verified by the forward–reverse reading scheme.

著者

Toshinao Takahashi Toshio Nagai Masato Kanda Mei-Lan Liu Naomichi Kondo Atsuhiko T Naito Takehiko Ogura Haruaki Nakaya Jong-Kook Lee Issei Komuro Yoshio Kobayashi

出版者

The Japanese Circulation Society

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

vol.79, no.12, pp.2703-2712, 2015-11-25 (Released:2015-11-25)

参考文献数

42

被引用文献数

7 17

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Background:Adipose tissue is one of the sources of mesenchymal stem cells, which have the potential to differentiate into various types of cells, including myocytes. Whether brown adipose tissue (BAT)-derived cells might differentiate into the cardiac pacemaking-conducting cells, and have the potential to regenerate the cardiac conduction system (CCS), is investigated in this study.Methods and Results:BAT was isolated from the interscapular area of mice and enzymatically digested before culture. Round or fusiform cells showed spontaneous beating at 4–7 days after culturing of BAT-derived cells. Reverse transcriptase-polymerase chain reaction analysis and immunocytochemical analysis revealed that BAT-derived cells expressed several cardiomyocytes, the CCS and pacemaker (PM) cell marker genes and proteins. Patch-clamp techniques revealed that spontaneous electrical activity and the shape of the action potential showed properties of cardiac PM cells. Next, a complete atrioventricular (AV) block was created in mice and green fluorescent protein-positive (GFP (+)) BAT-derived cells were injected intramyocardially around the AV node. At 1 week after transplantation, 50% of BAT-derived cells injected mice showed a sinus rhythm or a 2:1 AV block. Immunohistochemical analysis revealed that injected GFP (+) cells were engrafted and some GFP (+) cells co-expressed several cardiac PM cell marker proteins.Conclusions:BAT-derived cells differentiate into the CCS and PM-like cells in vitro and in vivo, and may become a useful cell source for arrhythmia therapy. (Circ J 2015; 79: 2703–2712)

著者

北上 誠一 村上 由里子 安永 廣作 阿部 洋一 加藤 登 新井 健一 SEIICHI KITAKAMI YURIKO MURAKAMI KOSAKU YASUNAGA YOICHI ABE NOBORU KATO KEN-ICHI ARAI 社団法人全国すり身協会 社団法人全国すり身協会 独立行政法人水産総合研究センター中央水産研究所 カネテツデリカフーズ株式会社 東海大学海洋学部 社団法人全国すり身協会 National Surimi Manufacturers Association National Surimi Manufacturers Association National Research Institute of Fisheries Science Kanetetsu Delica Foods Inc. School of Marine Science and Technology Tokai University National Surimi Manufacturers Association

出版者

The Japanese Society of Fisheries Science

雑誌

日本水産学会誌 = Bulletin of the Japanese Society of Scientific Fisheries (ISSN:00215392)

巻号頁・発行日

vol.75, no.2, pp.250-257, 2009-03-15

参考文献数

17

被引用文献数

2 3

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等級の異なる10種のスケトウダラ冷凍すり身に加水して調製した加熱ゲルの破断強度(BS),破断凹み,及びゲル剛性(Gs)とタンパク質(P)濃度の関係を解析した。そして,(1)BSとGsはP濃度に伴って指数関数的に増大,(2)加水しない加熱ゲルのBSとGsの最大値はすり身の等級が上位の方が高く,(3)BS vs Gsを図示すると,10種のすり身から得た加熱ゲルの両値の間に強い正の相関があった。これらの結果は,そのBSとGsのレベルとP濃度依存性から見積る加熱ゲル形成能が,冷凍すり身の品質要因の一として有用であることを示す。From ten lots of walleye pollack frozen surimis of various grades, the heated gels of different protein concentrations were prepared by adding 0-150% water. Breaking strength (BS), breaking strain (bs), and gel stiffness (Gs=BS/bs) were measured, and the effect of the protein concentration of the heated gel on their physical values was analyzed. The results were as follows: (1) Of all the surimis tested, the BS and Gs of the heated gel increased exponentially with the increase in the protein concentration of the heated gel. (2) The maximum values of BS and Gs of the heated gels formed without addition of water were higher in the order of SA>FA>A>KA>2nd grades of frozen surimi. (3) When BS was plotted against Gs, there was a close, positive correlation among those of the heated gels from the ten lots of frozen surimis of various grades. These results indicated that the heated gel forming ability, as measured by BS and Gs levels of the heated gel and its dependence on the protein concentration, is a useful parameter for judging the quality of walleye pollack frozen surimi.

著者

河城 孝史 山下 幸和 Xue-Jun Zhao 小山 恵理子 谷 昌尚 千葉 寛 石崎 高志

出版者

一般社団法人 日本臨床薬理学会

雑誌

臨床薬理 (ISSN:03881601)

巻号頁・発行日

vol.28, no.1, pp.175-176, 1997-03-31 (Released:2010-06-28)

参考文献数

3

著者

クラ-ク ケネス

出版者

日経BP社

雑誌

日経ビジネス (ISSN:00290491)

巻号頁・発行日

no.875, pp.66-69, 1997-01-27

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1月上旬来日し大蔵省のほか運輸,郵政各省と意見交換した。日本の「民営化」はその名に値しないほど不徹底だ,と語る。自分が今日本の政治家だったら,ビッグバンを支持する,とも。欧州統一通貨ができたところでシティの地位は揺るがないと自信。

著者

Shin-ichi Watanabe Masanori Matsuo Hiroaki Kitazawa Machiko Fukuda Atsushi Yamasaki Atsuko Uragami

出版者

The Japanese Society for Horticultural Science

雑誌

The Horticulture Journal (ISSN:21890102)

巻号頁・発行日

pp.OKD-161, (Released:2018-11-15)

被引用文献数

1

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In this study, we investigated the effect of high temperature on spear sprouting and elongation in asparagus to explore new approaches to control the harvest period in asparagus production. Four-year-old rootstocks of ‘UC157’ were grown in chambers in the dark at 30°C (30°C treatment), 34°C (34°C treatment), 38°C (38°C treatment), and 42°C (42°C treatment) for 14 days, and then at 25°C for 18 days. In the 42°C treatment, no spear sprouting was detected, and all rootstocks died. During the high temperature period, the number of sprouted spears was significantly lower in the 38°C treatment than in the 30°C treatment, whereas after the high temperature periods, the number was significantly higher in the 38°C treatment than in the 30°C and 34°C treatments. The total number of sprouted spears during and after the high temperature periods was not significantly different between the 30°C, 34°C, and 38°C treatments. The elongation rate of the spears during the high temperature period was significantly lower in the 38°C treatment than in the 30°C and 34°C treatments, whereas there were no significant differences in the mean spear elongation rate after the three high temperature treatments. These results suggest that a temperature of 38°C can be used to control spear sprouting reversibly by its application and cancellation.

著者

KIM Dong-Won

出版者

日本科学史学会

雑誌

Historia scientiarum. Second series : international journal of the History of Science Society of Japan (ISSN:02854821)

巻号頁・発行日

vol.19, no.2, pp.105-118, 2009-12-31

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Two atomic bombs dropped on Hiroshima and Nagasaki in August 1945 brought the unexpected liberation of Korea from the 35-year Japanese occupation. Koreans therefore had a very favorable and positive image of the nuclear bomb and nuclear energy from the beginning. The image of the nuclear bomb as "savior" was strengthened during the Korean War when the United States openly mentioned the possible use of the nuclear bomb against North Korean and Chinese military. After the end of the Korean War in July 1953 South Koreans strongly supported the development of the nuclear bomb in order to deter another North Korean invasion. When the US government provided South Korea with a research nuclear reactor in the late 1950s, most South Koreans hailed it as the first step to developing their own nuclear bomb. This paper will analyze how and why the savior image of the nuclear bomb originated and spread in Korea during the 1950s.

著者

Keiko Kawashima traduit du japonais par Ayako Lécaille-Okamura avec un avant-propos d'Élisabeth Badinter

出版者

Champion

巻号頁・発行日

2013

著者

スミンキ- 陽子

出版者

沖縄大学

雑誌

沖縄大学人文学部紀要 (ISSN:13458523)

巻号頁・発行日

vol.13, pp.41-48, 2011-03-31

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アニ-ベイビ-はネット作家として彗星のごとく中国の文壇に現れた、まさにIT時代が生み出したニュ-ジェネレ-ションの新進気鋭の作家である。本稿でとりあげる『さよならビビアン』は、作者が初めて出版した同名小説集に収められたデビュ-作である。作者は「人間関係における授受及び被授受」そして「混沌とした社会に生きる人々がもつ孤独と困惑」を重要なテーマに掲げている。本稿ではアニ-ベイビ-のデビュ-作、及びその他の著作に共通して作者が描き続ける「日常生活の中にある非日常的なストーリ-」に着目し、『さよならビビアン』における人間関係、言語運用の角度から登場人物の心理に焦点を当てて論を進める。