著者
Takanori Koitaya Susumu Yamamoto Iwao Matsuda Jun Yoshinobu
出版者
The Japan Society of Vacuum and Surface Science
雑誌
e-Journal of Surface Science and Nanotechnology (ISSN:13480391)
巻号頁・発行日
vol.17, pp.169-178, 2019-11-02 (Released:2019-11-02)
参考文献数
86
被引用文献数
4 13

In-situ analysis of heterogeneous catalysts under reaction condition is indispensable to understand reaction mechanisms and nature of active sites. Ambient-pressure X-ray photoelectron spectroscopy (AP-XPS) is one of the powerful methods to investigate chemical states of catalysts and reaction intermediates adsorbed on the surface. In this review, reaction of carbon dioxide on Cu(997) and Zn-deposited Cu(997) surfaces are discussed as an example of surface chemistry of weakly adsorbed molecules, together with a brief overview of recent progress in AP-XPS methods.
著者
Nomura Kyoko Minamizono Sachiko Maeda Eri Kim Roseline Iwata Toyoto Hirayama Junko Ono Kyoichi Fushimi Masahito Goto Takeshi Mishima Kazuo Yamamoto Fumio
出版者
BioMed Central
雑誌
Environmental Health and Preventive Medicine (ISSN:1342078X)
巻号頁・発行日
vol.26, no.30, 2021-03-05

Background We aimed to estimate the prevalence of depressive symptoms as well as suicide-related ideation among Japanese university students during the stay-home order necessitated by the coronavirus disease 2019 pandemic in Japan, and offer evidence in support of future intervention to depression and suicide prevention strategies among college and university students. Methods The data for this cross-sectional study were derived from the Student Mental Health Survey conducted from May 20 to June 16, 2020 at a national university in Akita prefecture. Among the 5111 students recruited, 2712 participated in this study (response rate, 53%; mean age ± standard deviation, 20.5 ±3.5 years; men, 53.8%). Depressive symptoms were identified by using the Patient Health Questionnaire-9 (PHQ-9). Results The prevalence of moderate depressive symptoms based on a PHQ-9 score ≥10 and suicide-related ideation based on question 9 of PHQ-9 ≥1, which encompasses thoughts of both suicide and self-harm, was 11.7% and 6.7%, respectively. Multivariable logistic regression analyses showed that risk factors for depression included being a woman, smoking, alcohol consumption, and social network communication using either video or voice. For suicide-related ideation, alcohol consumption was the only risk factor. Exercise and having someone to consult about worries were associated with decreased risk of both depressive symptoms and suicide-related ideation. Conclusions Negative lifestyles of smoking and drinking, and being a woman, may be important risk factors for depressive symptoms, whereas exercise and having someone to consult about worries may be protective factors.
著者
Kenta Hayashino Yusuke Meguri Aya Komura Chisato Matsubara Yutarou Shiraishi Chikamasa Yoshida Kazuhiko Yamamoto Kenji Imajo
出版者
The Japanese Society of Internal Medicine
雑誌
Internal Medicine (ISSN:09182918)
巻号頁・発行日
pp.8122-21, (Released:2021-11-13)
参考文献数
14

Scurvy is a rare disease caused by a vitamin C deficiency. Vitamin C is a water-soluble vitamin found in vegetables and fruits, but it is lost after boiling. A 59-year-old man presented with gingival pain after having a tooth extracted five years previously. Following the procedure, his diet comprised boiled vegetables to prevent pain. He then experienced bilateral lower leg pain, and computed tomography revealed intramuscular bleeding. His serum vitamin C level was below the detectable limit. His symptoms immediately improved with vitamin C administration. This case emphasized that consuming only boiled vegetables can lead to the onset of scurvy.
著者
山本 俊行 YAMAMOTO Toshiyuki 北村 隆一 KITAMURA Ryuichi 熊田 善亮 KUMADA Yoshiaki
出版者
土木学会
雑誌
土木学会論文集 (ISSN:02897806)
巻号頁・発行日
vol.667, no.50, pp.33-40, 2001-01

業務トリップは、通勤トリップと異なり広い時間帯で発生することや、複数の目的地を持つトリップチェインを形成する傾向が強い等の特徴を持つ。本研究では、トリップチェイン前後の業務活動も含めたトリップチェイン全体の費用最小化行動を仮定した、業務トリイプの経路・出発時刻選択モデルを構築した。出発時刻選択については最適な出発時刻で総費用が極小値をとるとの条件を用い、連続時間軸上での時刻選択行動をモデル化した。路側配布によるアンケート調査で得られた実際のトリップチェインデータ、および時間帯別所要時間データに基づき未知パラメータを推定した。さらに、出発時刻や経路、立ち回り順序の変更や所要時間の変化に伴なう費用の変化を産出し、モデルの挙動を確認した。Unlike commute trips, business trips are generated throughout business hours, and several destinations tend to be visited in a trip chain. In this study, a route and departure time choice model for a business trip chain is developed based on the hypothesis that the trip chain is made so as to minimize the total cost, including costs associated with other business activities before and after the trip chain, as well as costs associated with travel time, toll fees, and the probability of being late. The empirical analysis is carried out using a data set obtained from a survey of business trip drivers. The properties of the estimated model are examined on a sample case
著者
Musubu Takahashi Ayaka Kubota Tomoya Fujie Yasuhiro Shinkai Yoshito Kumagai Tsuyoshi Nakano Takato Hara Chika Yamamoto Toshiyuki Kaji
出版者
The Pharmaceutical Society of Japan
雑誌
BPB Reports (ISSN:2434432X)
巻号頁・発行日
vol.4, no.6, pp.175-181, 2021 (Released:2021-11-12)
参考文献数
27
被引用文献数
2

Fibroblast growth factor-2 (FGF-2) regulates several vascular endothelial cell functions, including proliferation. It has been suggested that the regulation may be modulated by reactive sulfur species (RSS), which are hydrogen sulfide and biomolecules containing persulfide/polysulfide groups. Since RSS promote vascular endothelial cell proliferation, we hypothesized that FGF-2 regulates the levels of RSS-producing enzymes in the cells. Bovine aortic endothelial cells were cultured and treated with FGF-2, and intracellular RSS levels were determined. The expression of RSS-producing enzymes, cystathionine γ-lyase (CSE), cystathionine β-synthase, 3-mercaptopyruvate sulfurtransferase, and cysteinyl-tRNA synthetase 2, was evaluated, and the intracellular signaling pathway that mediates FGF-2 regulation of RSS accumulation was investigated. We revealed that FGF-2 upregulates the expression of RSS by selectively inducing CSE via the ERK1/2 signaling pathway in vascular endothelial cells. The effect of FGF-2 on the function of vascular endothelial cells may be modulated by intracellular RSS, especially higher-molecular-mass RSS such as protein persulfide, the levels of which are increased by the growth factor.
著者
So TANABE Satohiro ITAGAKI Shuyi SUN Kyohei MATSUI Takamasa KINOSHITA Shigeki NISHII Yojiro YAMAMOTO Yasuhiro SADANAGA Hiroshi SHIIGI
出版者
The Japan Society for Analytical Chemistry
雑誌
Analytical Sciences (ISSN:09106340)
巻号頁・発行日
vol.37, no.11, pp.1597-1601, 2021-11-10 (Released:2021-11-10)
参考文献数
27
被引用文献数
2

Enterohemorrhagic Escherichia coli are a dangerous bacterium known to be harmful to the human body, with some infections even resulting in death. Given this danger, food factories are required to perform a quick bacterial test to confirm the absence of this pathogen prior to shipping. We have developed a novel molecular imprinting polymer (MIP) particle that has encapsulated gold nanoparticles (AuNPs) and which can function as both a receptor and an optical signal transmitter in biological systems. This MIP particle is artificially synthesized and can be engineered to specifically recognize and capture antigens on the bacterial cell membrane. In addition, MIP particles containing AuNPs generate strong scattered light signals, and binding of the MIP particles improves the optical intensity of the target bacterial cells. This enables clear visualization under a dark-field microscope and quantification of the target bacteria using the scattering light intensity. Here we describe the successful quantification of Escherichia coli O157 cells in real meat samples using this technology in conjunction with a simple labelling step.
著者
小野 朋典 Midorikawa Yoshiyuki Yamamoto Satoshi Ujiie Hiroshi 小野 朋典 緑川 義行 山本 聰 氏家 宏
出版者
琉球大学理学部
雑誌
琉球大学理学部紀要 (ISSN:02869640)
巻号頁・発行日
no.47, pp.p115-151, 1989-03
被引用文献数
1

本報告は1984年から1987年にかけて実施された琉球大学海洋学科の乗船実習RN-84,-86,及び-87航海で得られた,沖縄本島南方沖,慶良問ギャップ,石垣・西表島周辺海域からの底質サンプルの記載を主目的とする。採取されたサンプルはピストン・コアが8点,グラブ・サンプルが6点, ドレッジ・サンプルが25点に及んだ。記載に先立って行なった予察的研究の結果,次のような点が示唆された。1) 慶良問ギャップ(海裂)では,in situ の島尻層群最上部の泥岩を抜くピストン・コアや,同層群の鮮新銃から最下部更新統部分にわたる泥岩礁を含むドレッジ・サンプルのほかに,浮遊性有孔虫殻を多く含む lime-grainstone (更新統石灰岩?)が採取された.今後の調査で音波探査や深海カメラ等による海底観察と並行した底質サンプリングが行なわれるならば,本海裂の形成運動解明に貢献するであろう。2) 石垣・西表島南方の海溝斜面が先島海段に達する区域の水深2675mの地点より,石灰質砂層と半深海性シルト層の繰り返しから成る turbidite のピストン・コアを採取した。島弧の傾動運動との関連性を,今後追及すべきであろう。そのほかにも,径約5cmに達する大型底性有孔虫・Cycloclybeus carpenteriの生態に関する情報や,西表海底火山が想定されていた位置からの lime-grainstone の採取など,注目すべき材料が得られた。
著者
竹本 由美子 柿崎 優 北岡 美与 園田 のぞみ 山本 梨沙 Yumiko Takemoto Yu Kakizaki Miyo Kitaoka Nozomi Sonoda Risa Yamamoto
出版者
武庫川女子大学大学院生活環境学専攻 ; 2013-
雑誌
生活環境学研究 = Mukogawa journal of human environmental sciences : 教育・研究誌 (ISSN:21883335)
巻号頁・発行日
no.5, pp.78-81, 2017

日本繊維機械学会・繊維リサイクル技術研究会が主催となり開催された"2017第4回繊維リサイクルアイデアコンペティション"において,本学科の学生4名が「学生服からできた材料の使い方の提案」として『3WAY防災KABANchan』を発表し,優秀賞とベストプレゼンテーション賞を受賞した。コンペティションへの参加は,本研究室に配属が決まった3年生が「卒業基礎演習」の課題として取り組んだことが始まりである。本稿では,繊維リサイクルアイデアコンペティションの趣旨と衣服のリサイクルの現状について触れながら,今回の提案内容について報告する。
著者
Yoshizawa Kazunori Yamamoto Shuhei
出版者
The Research Faculty of Agriculture, Hokkaido University
雑誌
Insecta matsumurana. New series : Journal of the Research Faculty of Agriculture Hokkaido University, series entomology. (ISSN:00201804)
巻号頁・発行日
vol.77, pp.1-15, 2021-10

We describe a new psocid genus and species, Burmesopsocus lienhardi Yoshizawa, based on a fossil specimen embedded in mid-Cretaceous Burmese (Kachin) amber. Phylogenetic analysis based on the morphological data strongly suggest that the species is a member of the suborder Psocomorpha and may belong to the infraorder Homilopsocidea. However, its familial placement could not be determined. Therefore, this species is treated here as incertae sedis within Homilopsocidea without assigning it to any known family. This is the oldest fossil record of Psocomorpha and represents the first occurrence of the suborder from Kachin amber. The present discovery of a mid-Cretaceous homilopsocid species will contribute greatly to calibrating the time tree of Psocodea.
著者
Yuichi Sawayama Takashi Yamamoto Yukinori Tomita Kohei Asada Noriaki Yagi Megumi Fukuyama Akashi Miyamoto Hiroshi Sakai Tomoya Ozawa Tetsuichiro Isono Daiki Hira Tomohiro Terada Minoru Horie Yoshihisa Nakagawa
出版者
The Japanese Circulation Society
雑誌
Circulation Journal (ISSN:13469843)
巻号頁・発行日
vol.84, no.9, pp.1575-1581, 2020-08-25 (Released:2020-08-25)
参考文献数
18
被引用文献数
5 13

Background:The association between cytochrome P450 (CYP) 2C19 genotypes and adverse events in patients treated with clopidogrel or prasugrel after percutaneous coronary intervention (PCI) in the Japanese population is unclear.Methods and Results:This study consisted of 1,580 patients whoseCYP2C19genotypes were assessed at Shiga University of Medical Science Hospital, and 193 clopidogrel-treated and 217 prasugrel-treated patients who were followed more than 1 year after receiving PCI were analyzed. Among 1,580 patients, the prevalence of normal, intermediate, and poor metabolizers was 32%, 49%, and 17%, respectively. Overall incidence of the primary outcome, defined as a composite of cardiovascular death, myocardial infarction, definite stent thrombosis, ischemic stroke, or major bleeding was not significantly different between the clopidogrel and prasugrel groups (adjusted hazard ratio [HR] 1.98, 95% confidence interval [CI] 0.85–4.61, P=0.12). Among patients with theCYP2C19loss-of-function (LOF) allele, however, the incidence of the primary outcome was significantly higher in the clopidogrel group (adjusted HR 3.19, 95% CI 1.10–9.24, P=0.03), whereas no difference was observed among patients without theCYP2C19LOF allele (adjusted HR 0.67, 95% CI 0.14–3.26, P=0.62).Conclusions:Among patients with theCYP2C19LOF allele, the use of clopidogrel was significantly associated with increased adverse events. Thus, further investigation is needed to establish the practical use ofCYP2C19genotyping.
著者
Koichiro Fujisue Eiichiro Yamamoto Daisuke Sueta Yuichiro Arima Kyoko Hirakawa Noriaki Tabata Masanobu Ishii Miwa Ito Kenshi Yamanaga Shinsuke Hanatani Tadashi Hoshiyama Hisanori Kanazawa Seiji Takashio Satoshi Araki Hiroki Usuku Taishi Nakamura Hirofumi Soejima Koichi Kaikita Hiroaki Kawano Kenichi Matsushita Kenichi Tsujita
出版者
Japan Atherosclerosis Society
雑誌
Journal of Atherosclerosis and Thrombosis (ISSN:13403478)
巻号頁・発行日
pp.63044, (Released:2021-09-28)
参考文献数
37
被引用文献数
7

Aims: Royal jelly, a creamy substance secreted by honeybees, has been reported to have beneficial effects against dyslipidemia and metabolic syndrome. However, the effects of royal jelly on atherogenesis remain unknown. Hence, we prospectively evaluated whether royal jelly augments vascular endothelial function, which can reflect early atherogenesis, in healthy volunteers. Methods: This was a single-center, double-blind, 1:1 randomized placebo-controlled study conducted from October 2018 to December 2019. A total of 100 healthy volunteers were randomly assigned to receive either royal jelly 690 mg or placebo daily for 4 weeks. The primary endpoint was augmentation in vascular endothelial function as assessed using the change in the reactive hyperemia peripheral arterial tonometry index (RH-PAT) index, and the secondary endpoints were the changes in liver function and lipid profiles between baseline and 4 weeks after enrollment. Results: The mean age of the participants was 35.0±9.3 years in the placebo group and 36.1±9.1 years in the royal jelly groups; 45% and 50% of the placebo and the royal jelly groups, respectively, were male. The percentage relative change in the RH-PAT index was significantly higher in the royal jelly group than in the placebo group (21.4%±53.1% vs. 0.05%±40.9%, P=0.037). The percentage relative changes in alanine aminotransferase and γ-glutamyl transpeptidase were significantly lower in the royal jelly group than in the placebo group (alanine aminotransferase: −6.06%±22.2% vs. 11.6%±46.5%, P=0.02; γ-glutamyl transpeptidase: −3.45%±17.8% vs. 4.62%±19.4%, P=0.045). Lipid profiles were not significantly different between the two groups. Conclusions: Royal jelly might have antiatherogenic property by improving vascular endothelial function. It also augmented liver functions in healthy volunteers.
著者
Yamamoto Goro
出版者
映画英語教育学会
雑誌
映画英語教育研究 : 紀要 (ISSN:13429914)
巻号頁・発行日
vol.17, pp.13-20, 2012

This paper discusses the usage and meaning of the present progressive futurate from the perspective of English grammar teaching and proposes an alternative method of teaching this grammatical concept, which involves the use of films. This paper first analyzes the data and observations presented in related previous studies and verifies the validity of the following three specific constraints on the usage of the present progressive futurate that they proposed: the constraint on action, constraint on verb types, and proximity of time reference. The analyses of each constraint with data-in the form of dialogues-from English films highlight the grammatical features and meaning of the present progressive futurate. Real-life problems that are associated with English grammar teaching and are caused by these constraints are discussed. Subsequently, this paper proposes a method for teaching this futurate. This method involves comparing the usage of two of the more familiar English future expressions-will + infinitive and be going to-in the dialogues of the films such as Ocean's Twelve (2004) and Catch Me If You Can (2002). This comparison enables EFL learners to grasp the pragmatic differences among future expressions and better understand the meaning of the present progressive futurate.
著者
Masahiro Natsuaki Takeshi Morimoto Hiroki Shiomi Ko Yamamoto Kyohei Yamaji Hirotoshi Watanabe Takashi Uegaito Mitsuo Matsuda Toshihiro Tamura Ryoji Taniguchi Moriaki Inoko Hiroshi Mabuchi Teruki Takeda Takenori Domei Manabu Shirotani Natsuhiko Ehara Hiroshi Eizawa Katsuhisa Ishii Masaru Tanaka Tsukasa Inada Tomoya Onodera Ryuzo Nawada Eiji Shinoda Miho Yamada Takashi Yamamoto Hiroshi Sakai Mamoru Toyofuku Takashi Tamura Mamoru Takahashi Tomohisa Tada Hiroki Sakamoto Takeshi Tada Kazuhisa Kaneda Shinji Miki Takeshi Aoyama Satoru Suwa Yukihito Sato Kenji Ando Yutaka Furukawa Yoshihisa Nakagawa Kazushige Kadota Takeshi Kimura on behalf of the CREDO-Kyoto PCI/CABG Registry Cohort-Investigators
出版者
The Japanese Circulation Society
雑誌
Circulation Journal (ISSN:13469843)
巻号頁・発行日
pp.CJ-21-0526, (Released:2021-09-16)
参考文献数
27
被引用文献数
1

Background:Optimal intensity is unclear for P2Y12receptor blocker therapy after percutaneous coronary intervention (PCI) in real-world clinical practice.Methods and Results:From the CREDO-Kyoto Registry, the current study population consisted of 25,419 patients (Cohort-2: n=12,161 and Cohort-3: n=13,258) who underwent their first PCI. P2Y12receptor blocker therapies were reduced dose of ticlopidine (200 mg/day), and global dose of clopidogrel (75 mg/day) in 87.7% and 94.8% of patients in Cohort-2 and Cohort-3, respectively. Cumulative 3-year incidence of GUSTO moderate/severe bleeding was significantly higher in Cohort-3 than in Cohort-2 (12.1% and 9.0%, P<0.0001). After adjusting 17 demographic factors and 9 management factors potentially related to the bleeding events other than the type of P2Y12receptor blocker, the higher bleeding risk in Cohort-3 relative to Cohort-2 remained significant (hazard ratio (HR): 1.52 95% confidence interval (CI) 1.37–1.68, P<0.0001). Cohort-3 compared with Cohort-2 was not associated with lower adjusted risk for myocardial infarction/ischemic stroke (HR: 0.96, 95% CI: 0.87–1.06, P=0.44).Conclusions:In this historical comparative study, Cohort-3 compared with Cohort-2 was associated with excess bleeding risk, which might be at least partly explained by the difference in P2Y12receptor blockers.