著者
Chika YAMAMOTO
出版者
The Japan Association of Applied Psychology
雑誌
応用心理学研究 (ISSN:03874605)
巻号頁・発行日
vol.46, no.SpecialEdition, pp.1-10, 2020-07-31 (Released:2020-10-31)
参考文献数
28

The present study investigated the features of the motivation at return to work in EY (Early Years) through the comparison of the UK & Japan, which had opposite direction in a recent policy reform of EY settings. I set the Five groups of 43 returners (13 Nursery Returners & 5 Other occupations Returners in Japan, 5 Nursery Returners, 6 Other occupations Returners, & 14 Returner applicants in England) and collected interview data. The text mining analysis of each group and compared with them chiefly focused on the words that co-occurred with 'Work', and got to 3 findings about the features of Japanese EY returners; 1. Their priority was their own children, the same as Japanese returners in other occupations. 2. They had an ambivalent attitude for their EY qualification. 3. The ratio of the negative relations between "work/working" and "I/myself" was higher. These tendencies regarded as the relation with the lower-leveled professionalism, and a poorer employment practice in part-time working in Japan EY facilities.
著者
Yohei Yamamoto Hidetoshi Uchiyama Masahiro Oonuki
出版者
International Heart Journal Association
雑誌
International Heart Journal (ISSN:13492365)
巻号頁・発行日
pp.22-153, (Released:2022-09-14)
参考文献数
6

Some patients with aortic arch aneurysm are ineligible for open repair because of excessive perioperative risk, and others may not be suited for total endovascular repair due to anatomic constraints. We herein report a case of aortic arch aneurysm in a 94-year-old woman. The patient underwent hybrid aortic arch repair consisting of total arch debranching using bilateral femoral artery inflow and thoracic endovascular aortic repair. The patient was discharged without complications and is in good condition with dependent ambulation at 14 months of follow-up. Although a careful selection of cases is highly recommended, the use of the femoral artery inflow for arch debranching is considered to be a viable rescue option for high-risk patients.
著者
Kazuya ZAITSU Koji YAMAMOTO Yasuto KURODA Kazunari INOUE Shingo ATA Ikuo OKA
出版者
The Institute of Electronics, Information and Communication Engineers
雑誌
IEICE Transactions on Communications (ISSN:09168516)
巻号頁・発行日
vol.E95.B, no.7, pp.2306-2314, 2012-07-01 (Released:2012-07-01)
参考文献数
26
被引用文献数
1 2

Ternary content addressable memory (TCAM) is becoming very popular for designing high-throughput forwarding engines on routers. However, TCAM has potential problems in terms of hardware and power costs, which limits its ability to deploy large amounts of capacity in IP routers. In this paper, we propose new hardware architecture for fast forwarding engines, called fast prefix search RAM-based hardware (FPS-RAM). We designed FPS-RAM hardware with the intent of maintaining the same search performance and physical user interface as TCAM because our objective is to replace the TCAM in the market. Our RAM-based hardware architecture is completely different from that of TCAM and has dramatically reduced the costs and power consumption to 62% and 52%, respectively. We implemented FPS-RAM on an FPGA to examine its lookup operation.
著者
Naoki Yamamoto Eri Chatani
出版者
The Biophysical Society of Japan
雑誌
Biophysics and Physicobiology (ISSN:21894779)
巻号頁・発行日
vol.19, pp.e190017, 2022 (Released:2022-06-01)
参考文献数
34
被引用文献数
1

It is crucial to understand the mechanism of amyloid fibril formation for the development of the therapeutic ways against amyloidoses and neurodegenerative diseases. Prefibrillar intermediates, which emerge prior to the fibril formation, seem to play a key role to the occurrence of nuclei of amyloid fibrils. We have focused on an insulin-derived peptide, B chain, to precisely clarify the mechanism of the fibril formation via prefibrillar intermediates. Various kinds of methods such as circular dichroism spectroscopy, dynamic light scattering, small-angle X-ray scattering, and atomic force microscopy were employed to track the structural changes in prefibrillar intermediates. The prefibrillar intermediates possessing rod-shaped structures elongated as a function of time, which led to fibril formation. We have also found that a blood clotting protein, fibrinogen, inhibits the amyloid fibril formation of B chain. This was caused by the stabilization of prefibrillar intermediates and thus the suppression of their elongation by fibrinogen. These findings have not only shed light on detailed mechanisms about how prefibrillar intermediates convert to the amyloid fibril, but also demonstrated that inhibiting the structural development of prefibrillar intermediates is an effective strategy to develop therapeutic ways against amyloid-related diseases. This review article is an extended version of the Japanese article, Observing Development of Amyloid Prefibrillar Intermediates and their Interaction with Chaperones for Inhibiting the Fibril Formation, published in SEIBUTSU BUTSURI Vol. 61, p. 236–239 (2021).
著者
Shusuke YAMAMOTO Daina KASHIWAZAKI Haruto UCHINO Hisayasu SAITO Naoki AKIOKA Naoya KUWAYAMA Satoshi KURODA
出版者
The Japan Neurosurgical Society
雑誌
Neurologia medico-chirurgica (ISSN:04708105)
巻号頁・発行日
vol.60, no.7, pp.360-367, 2020 (Released:2020-07-15)
参考文献数
21
被引用文献数
5 11

Some of the pediatric moyamoya patients spend their childhood without diagnosed as moyamoya disease (MMD) because of their mild ischemic attacks and emerge again with ischemic or hemorrhagic stroke in their adulthood. This study was aimed to clarify the clinical characteristics of adult moyamoya patients with childhood onset and elucidate the impact of long disease period on their clinical features. Present study included 116 untreated hemispheres of 69 adult patients with MMD. They were divided into two groups: childhood onset group (26 hemispheres of 14 patients) and adult onset group (90 hemispheres of 55 patients). Clinical features were compared between the two groups. The incidence of hemorrhagic stroke was significantly higher in childhood onset group (P = 0.0091). Lenticulostriate and choroidal channels were more developed in childhood onset group (P = 0.044 and P <0.001, respectively). Vault moyamoya was more frequently observed in childhood onset group (P <0.001). The development of surgical collaterals through indirect bypass was more marked in childhood onset group (P = 0.0019). Multivariate analysis revealed that childhood onset and developed choroidal channels were significantly associated with the occurrence of hemorrhagic stroke (OR 4.31 [95% CI 1.21–15.4], P = 0.025 and OR 6.78 [95% CI 1.78–25.8], P = 0.0050, respectively). This study clearly shows that adult moyamoya patients with childhood onset have more developed spontaneous collaterals, which may, in turn, highly causes hemorrhagic stroke. Adult moyamoya patients with “childhood onset” should be recognized as a novel and important concept when elucidating the underlying mechanisms of hemorrhagic stroke in MMD.
著者
Kazumasa Oshima Masataka Sakamoto Kazumasa Morita Kenichi Kon Ken-ichi Shimizu Tsuyoshi Yamamoto Masahiro Kishida Shigeo Satokawa
出版者
The Society of Chemical Engineers, Japan
雑誌
JOURNAL OF CHEMICAL ENGINEERING OF JAPAN (ISSN:00219592)
巻号頁・発行日
vol.55, no.7, pp.243-247, 2022-07-20 (Released:2022-07-20)
参考文献数
17
被引用文献数
2

The effective utilization of carbon fibers recovered during the thermal decomposition recycling of carbon-fiber-reinforced plastic (CFRP) was investigated. Carbon fibers have a uniform diameter and a suitable size for the use as a combustion catalyst for particulate matter (PM). Thus, in this study, carbon fibers were used as a template to synthesize hollow-form LaNiO3 perovskite-type oxide via the precursor accumulation method. The calcination temperature was lowered by the internal heat supply from the combustion of the carbon template. Hollow-form LaNiO3 exhibited the same chemical properties as LaNiO3 prepared via the common sol–gel method. The morphology of the hollow form decreased the bulk density of the catalyst, resulting in enhanced contact with PM and, consequently, high PM combustion efficiency.
著者
Manami MONOBE Kaori EMA Yoshiko TOKUDA Mari MAEDA-YAMAMOTO
出版者
Japan Society for Bioscience, Biotechnology, and Agrochemistry
雑誌
Bioscience, Biotechnology, and Biochemistry (ISSN:09168451)
巻号頁・発行日
vol.74, no.12, pp.2501-2503, 2010-12-23 (Released:2010-12-23)
参考文献数
12
被引用文献数
19

We found that the epigallocatechin gallate (EGCG)/epigallocatechin (EGC) ratio in a green tea (Camellia sinensis L.) extract was affected by the extraction temperature. The EGCG/EGC ratio in the 4 °C extract was around 1:3-4, whereas in the 100 °C extract, it was around 1:0.7. Oral administration of the mixture with a high EGC ratio (1:2-3 = EGCG/EGC) resulted in greater IgA production by murine Peyer’s patch cells.
著者
Yuya Hagiwara Yoshiyuki Yamamoto Yuki Inagaki Reina Tomisaki Miki Tsuji Soma Fukuda Satoshi Fukuda Tsubasa Onoda Hirosumi Suzuki Yusuke Niisato Yoshitaka Tange Naoya Ikeda Keiichi Yamada Mariko Kobayashi Daisuke Akutsu Takeshi Yamada Toshikazu Moriwaki Toshiaki Narasaka Hideo Suzuki Kiichiro Tsuchiya
出版者
The Japanese Society of Internal Medicine
雑誌
Internal Medicine (ISSN:09182918)
巻号頁・発行日
vol.61, no.16, pp.2449-2455, 2022-08-15 (Released:2022-08-15)
参考文献数
43
被引用文献数
1

Dihydropyrimidine dehydrogenase (DPD) deficiency induces severe adverse events in patients receiving fluoropyrimidines. We encountered a 64-year-old DPD-deficient man with a severe capecitabine-related gastrointestinal disorder. He received capecitabine-containing chemotherapy after rectal cancer resection. During the first course of chemotherapy, he developed severe diarrhea, a fever, and hematochezia. Endoscopy revealed mucosal shedding with bleeding throughout the gastrointestinal tract. DPD deficiency was suspected because he developed many severe adverse events of capecitabine early and was finally confirmed based on the finding of a low DPD activity level in peripheral blood mononuclear cells. After one month of intensive care, hemostasis and mucosal healing were noted, although his gastrointestinal function did not improve, and he had persistent nutritional management issues.
著者
Sunao Kojima Takeshi Yamamoto Migaku Kikuchi Hiroyuki Hanada Toshiaki Mano Takahiro Nakashima Katsutaka Hashiba Akihito Tanaka Junichi Yamaguchi Kunihiro Matsuo Naoki Nakayama Osamu Nomura Tetsuya Matoba Yoshio Tahara Hiroshi Nonogi for the Japan Resuscitation Council (JRC) Acute Coronary Syndrome (ACS) Task Force and the Guideline Editorial Committee on behalf of the Japanese Circulation Society (JCS) Emergency and Critical Care Committee
出版者
The Japanese Circulation Society
雑誌
Circulation Reports (ISSN:24340790)
巻号頁・発行日
vol.4, no.8, pp.335-344, 2022-08-10 (Released:2022-08-10)
参考文献数
24
被引用文献数
3

Background: In Japan, oxygen is commonly administered during the acute phase of myocardial infarction (MI) to patients without oxygen saturation monitoring. In this study we assessed the effects of supplemental oxygen therapy, compared with ambient air, on mortality and cardiac events by synthesizing evidence from randomized controlled trials (RCTs) of patients with suspected or confirmed acute MI.Methods and Results: PubMed was systematically searched for full-text RCTs published in English before June 21, 2020. Two reviewers independently screened the search results and appraised the risk of bias. The estimates for each outcome were pooled using a random-effects model. In all, 2,086 studies retrieved from PubMed were screened. Finally, 7,322 patients from 9 studies derived from 4 RCTs were analyzed. In-hospital mortality in the oxygen and ambient air groups was 1.8% and 1.6%, respectively (risk ratio [RR] 0.90; 95% confidence interval [CI] 0.38–2.10]); 0.8% and 0.5% of patients, respectively, experienced recurrent MI (RR 0.44; 95% CI 0.12–1.54), 1.5% and 1.6% of patients, respectively, experienced cardiac shock (RR 1.10; 95% CI 0.77–1.59]), and 2.4% and 2.0% of patients, respectively, experienced cardiac arrest (RR 0.91; 95% CI 0.43–1.94).Conclusions: Routine supplemental oxygen administration may not be beneficial or harmful, and high-flow oxygen may be unnecessary in normoxic patients in the acute phase of MI.
著者
Kazumasa Kurogi Masanobu Ishii Kenji Sakamoto Soichi Komaki Hiroaki Kusaka Nobuyasu Yamamoto Seiji Takashio Yuichiro Arima Eiichiro Yamamoto Koichi Kaikita Kenichi Tsujita
出版者
The Japanese Circulation Society
雑誌
Circulation Journal (ISSN:13469843)
巻号頁・発行日
vol.84, no.6, pp.917-925, 2020-05-25 (Released:2020-05-25)
参考文献数
31
被引用文献数
11 14

Background:The excessive volume of contrast needed is a significant limitation of optical coherence tomography (OCT)-guided percutaneous coronary intervention (PCI). Low-molecular-weight dextran (LMWD) has been used for OCT image acquisition instead of contrast media. This study compared the effects of OCT-guided PCI using LMWD on renal function and clinical outcomes to those of intravascular ultrasound (IVUS)-guided PCI.Methods and Results:In all, 1,183 consecutive patients who underwent intracoronary imaging-guided PCI were enrolled in this single-center, retrospective, observational study. After propensity score matching, 133 pairs of patients were assigned to undergo either OCT-guided PCI using LMWD or IVUS-guided PCI. There was no significant change from baseline in the primary endpoint, serum creatinine concentrations, after the procedure in either group. There were no significant differences between the OCT and IVUS groups in the volume of contrast medium, the incidence of contrast-induced nephropathy (1.5% vs. 2.3%; P=0.65), and major adverse cardiovascular events (MACE) at 30 days (2.3% vs. 6.0%; P=0.12) and 12 months (2.3% vs. 3.0%; P=0.70) after the procedure. Kaplan-Meier analysis at the 12-month follow-up revealed no significant difference in the incidence of MACE between the 2 groups (P=0.75).Conclusions:OCT-guided PCI using LMWD did not negatively affect renal function and achieved similar short- and long-term clinical outcomes to IVUS-guided PCI.
著者
山本 勉 荻野 愛海 花澤 明優美 Tsutomu YAMAMOTO Manami OGINO Ayumi HANAZAWA
雑誌
清泉女子大学人文科学研究所紀要 = BULLETIN OF SEISEN UNIVERSITY RESEARCH INSTITUTE FOR CULTURAL SCIENCE (ISSN:09109234)
巻号頁・発行日
no.39, pp.49-84,

東京都品川区荏原一丁目一―三・専修寺本尊阿弥陀如来および両脇侍像三軀は「木造阿弥陀三尊像」の名称で品川区指定有形文化財に指定されている。二〇一七年度の品川区文化財公開に関連して、二〇一七年八月に大学院思想文化専攻開講科目「美術史学演習Ⅲ」における演習の一環でこの三軀の調査を実施した。本稿では、調査の詳しい成果を報告し、あわせてこの一具の彫刻史上への正確な位置づけをおこなう。三軀は定印を結ぶ阿弥陀如来坐像に蓮華を捧げる左脇侍観音菩薩立像と合掌する勢至菩薩立像が随侍する来迎形の阿弥陀三尊像で、各像がヒノキ材の割矧ぎ造りの技法になる。阿弥陀如来像と左脇侍像のおだやかな姿は平安時代末期、十二世紀後半頃の製作とみられる。右脇侍像は少し作風が異なり、やや遅れる時期、鎌倉時代にはいってからの製作を思わせる。三尊は昭和二十二年(一九四七)に千葉県市原市の光明寺から移されたものであるが、阿弥陀如来像内の銘記によって、室町時代、永正五年(一五〇八)に上総国佐是郡池和田の正福寺の像として修理されたことが知られる。正福寺は昭和十五年に光明寺に合併された寺である。三尊の彫刻史上の問題としては、まず阿弥陀如来坐像の両脇に来迎形の両脇侍立像が随侍する形が平安時代最末期に特有のもので安元元年(一一七五)頃の製作とみられる神奈川・証菩提寺像と共通することがあげられる。また正福寺の寺名や修理関係者の名は、光明寺に現存し、やはりかつて池和田にあった東光寺本尊であったという薬師三尊像中尊の永正元年の銘記にもみえ、当時の池和田における修理や造像の活発な状況を想像することもできる。以上を総合して、この三尊が平安時代末期の時期の関東地方の造像の水準を示すものであると評価する。
著者
Shuhei Ota Shigeshi Fuchida Haruyo Yamaguchi Takahiro Yamagishi Hiroshi Yamamoto Hiroshi Koshikawa Masanobu Kawachi
出版者
Japan Mendel Society, International Society of Cytology
雑誌
CYTOLOGIA (ISSN:00114545)
巻号頁・発行日
vol.87, no.2, pp.177-187, 2022-06-25 (Released:2022-06-25)
参考文献数
41
被引用文献数
2

Seafloor resource development in the future is expected to be accompanied by the mining of metal ores, as these sulfide ores contain valuable metals. However, the mining process is detrimental to marine oceanic environments. As a precautionary approach, innovations in the collection of environmental baseline data and new onboard assessment methods for marine environmental impacts are required. Due to the low cell density in open ocean water, techniques for rapid impact assessment of seawater without sample concentration are required. The purpose of this study was to establish a heavy metal impact assessment system for seawater samples of marine microbes using a portable flow cytometer, On-chip Sort. We established a protocol for detecting heavy metal-induced damage to cells via propidium iodide (PI) staining using algal culture strains (Bathycoccus prasinos NIES-2670, Synechococcus sp. NIES-969, Prochlorococcus sp. NIES-2885, and Cyanobium sp. NIES-981) obtained from the marine environment maintained at the Microbial Culture Collection of the National Institute for Environmental Studies, Tsukuba, Japan. Results showed that PI staining could detect the effects of heavy metals on cells. The proportion of PI-positive cells increased with an increase in the concentration of heavy metal mixture or copper exposure. Compared to cyanobacteria, damaged cells of eukaryotic algae were detected. Therefore, the effects of heavy metals on both eukaryotic and prokaryotic algae can be rapidly assessed via PI-based flow cytometry using samples containing low cell densities.
著者
山本 忠行 YAMAMOTO Tadayuki
出版者
創価大学通信教育部学会
雑誌
通信教育部論集 (ISSN:13442511)
巻号頁・発行日
no.25, pp.71-91, 2022-08-07

「教科書で教える」ことは日本語教育の基本姿勢とされるにもかかわらず、定義が曖昧で、人によってその捉え方が異なる。一般教科、英語、国語などと比較しながら、「教科書で教える」ことの意義を再確認した上で、問題のある日本語教師が「教科書を教える」ことしかできないことを明らかにした。さらに初級と中上級で具体的にどのように「教科書で教える」のかを例示し、「教科書で教える」ことこそ、教育実習で身につけさせるべき技能であることを論じた。
著者
Yu Mikame Yui Sakai Ryo Tahara Kinuka Doi Tsuyoshi Yamamoto Chikara Dohno Takayuki Shibata Asako Yamayoshi
出版者
The Pharmaceutical Society of Japan
雑誌
Chemical and Pharmaceutical Bulletin (ISSN:00092363)
巻号頁・発行日
pp.c22-00333, (Released:2022-07-28)
参考文献数
23

Several psoralen-conjugated oligonucleotides (Ps-Oligos) have been developed as photo-crosslinkable oligonucleotides targeting DNA or RNA. To avoid potential off-target effects, it is important to investigate the selective photo-crosslinking reactivity of Ps-Oligos to DNA or RNA. However, the selectivity of these Ps-Oligos has not been reported in detail thus far. In this study, we evaluated the photo-crosslinking properties of two Ps-Oligos, 5’-Ps-Oligo and a novel Ps-Oligo containing 2’-O-{[(4,5’,8-trimethylpsoralen)-4’-ylmethoxy]ethylaminocarbonyl}adenosine (APs2-Oligo). Notably, 5’-Ps-Oligo preferentially crosslinked with DNA, whereas APs2-Oligo preferentially crosslinked with RNA. These results demonstrate the interesting crosslinking properties of Ps-Oligos, which will provide useful information for the molecular design of novel Ps-Oligos in future studies.