1 0 0 0 カメラ

著者
アルス
出版者
アルス
巻号頁・発行日
vol.21(2), no.225, 1940-02

1 0 0 0 カメラ

著者
アルス
出版者
アルス
巻号頁・発行日
vol.21(4), no.227, 1940-04
著者
石丸信一
雑誌
生物教材
巻号頁・発行日
vol.19, pp.91-105, 1985
被引用文献数
1
著者
Ping Zhang Jianfang Luo Tianlong Wu Xuan Wang Fan Yang Yanhong Yu Lihe Lu Huimin Yu
出版者
International Heart Journal Association
雑誌
International Heart Journal (ISSN:13492365)
巻号頁・発行日
vol.63, no.5, pp.928-938, 2022-09-30 (Released:2022-09-30)
参考文献数
39
被引用文献数
4

The role of endothelial injury and inflammation in atherosclerosis has been well established. miRNAs have been found to be key regulators in the development of atherosclerosis. Here we investigated whether miR-32-5p and its predicted target gene axin interactor, dorsalization associated (AIDA) are involved in endothelial injury and inflammation. Human umbilical vein endothelial cells (HUVECs) were treated with oxidized low-density lipoprotein (oxLDL) to induce endothelial injury and inflammation. AIDA was predicted to be a target gene of miR-32-5p using TargetScan software. Cell viability, migration, and angiogenesis were evaluated using Cell Counting Kit-8, wound-healing, and tube formation assays, respectively. The expression of inflammatory factors was detected using quantitative PCR, enzyme-linked immunosorbent assay, and western blot. We found that miR-32-5p expression was significantly decreased, whereas AIDA expression was significantly increased in oxLDL-treated HUVECs and the increased AIDA expression was reversed by the up-regulation of miR-32-5p. Moreover, both miR-32-5p mimic and knockdown of AIDA enhanced cell viability, promoted cell migration and angiogenesis and suppressed the expression of inflammatory factors including IL-1β, IL-6, TNF-α, ICAM-1, and VCAM-1 in oxLDL-induced HUVECs. Furthermore, miR-32-5p was verified to directly target AIDA using dual-luciferase reporter assay. Overall, these findings suggest that miR-32-5p/AIDA signal plays an important role in oxLDL-induced endothelial injury and inflammation. This study provides new insights into novel molecular mechanisms of endothelial dysfunction and atherosclerosis.
著者
青柳 悦子
出版者
筑波大学
雑誌
基盤研究(C)
巻号頁・発行日
2020-04-01

現在、自由化と市民社会の構築がめざましい勢いで進展しているマグレブ地域(アルジェリア、チュニジア、モロッコ)で新たに展開されつつある、フランス語を中心とする表現活動に注目し、21世紀における社会変革と文化創出の関係を照らし出す。とりわけ、アルジェリアで近年活発化した、比較的若い世代による日本式マンガを用いた創作活動に注目し、グローバル性とローカル性を併せ持ちつつ社会的共生意識を涵養する新たな大衆的表現活動として、その特質と意義を分析する。さらに、文学など他の表現ジャンルとの関係も含めた総合的な研究と、現地の文化活動の発展への寄与をめざす。
著者
平木 潔 太田 善介 入野 昭三 三好 勇夫 瀬崎 達雄 原田 英雄 鈴木 信也 大里 尚司 永森 俤一郎 守屋 純一郎 六車 昌士 高杉 潔 駄場崎 浩 池田 一彦
出版者
Okayama Medical Association
雑誌
岡山医学会雑誌 (ISSN:00301558)
巻号頁・発行日
vol.77, no.5-6, pp.795-835, 1965-06-30 (Released:2009-03-30)
参考文献数
229

Morphologic characteristics of most of known oncogenic viruses, some of which were investigated by us, were described in relation to their oncogenicity and their localizations in tumor tissues.Oncogenic viruses were classified into six groups: type A, B, C, D, E and F. Viruses pertaining to type A were presumably not mature virus particles. Some of them could, however, be immature form or incomplete form of oncogenic virus particles. Viruses belonging to type B, C, D, E, and F were represented by mammary tumor virus of mice, leukemia viruses of mice and chickens, polyoma virus, Shope fibroma virus and Lucké renal adenocarcinoma virus, respectively. They were different in size and shape, and in the mode of development.It was presumed that type B and C viruses were members of the Myxovisus group and type D viruses belonged to Adenovirus and the Papova virus group. It was also believed that type E and F viruses had in general the feature of the Pox virus group and Herpes virus group, respectively.

1 0 0 0 OA 古事類苑

著者
神宮司庁 編
出版者
古事類苑刊行会
巻号頁・発行日
vol.第51冊, 1928
著者
塩谷 英之
出版者
神戸大学
雑誌
基盤研究(C)
巻号頁・発行日
2010

食後、心拍数、血圧などの血行動態は大きく変化するため、しばしば生体に悪影響を及ぼす。従って食後の血行動態の詳細を明らかにすることは健康教育のために重要である。そこで本研究では食事が心拍数、血圧、自律神経活動等に及ぼす影響について(1)食事摂取量による影響(2)食事摂取時間による影響(3)若年健常者、壮年健常者、糖尿病患者における影響の違いの3つの観点から研究を行った。食事量の影響に関しては食事量の増大により、食後の心拍数の増大がより顕著になり、中心血圧が低下することを明らかになった。食事時間に関して特に夕食摂取時間が遅くなることが、深夜の心拍、血圧、自律神経活動のリズムを大きく障害することが明らかになった。若年健常者、壮年健常者、糖尿病患者における比較においては比較的軽症の糖尿病患者においても食後の自律神経活動の低下の結果、上腕血圧のみならず、中心血圧の低下が生じることが明らかになった。
著者
渡邊 裕也 来田 宣幸 甲斐 義浩 森原 徹
出版者
公益財団法人 明治安田厚生事業団 体力医学研究所
雑誌
体力研究 (ISSN:03899071)
巻号頁・発行日
vol.120, pp.1-8, 2022 (Released:2022-10-01)
参考文献数
16

Previous studies reported significant positive correlations between physical variables such as lower-limb muscular power and annual hitting records in baseball players. Thus, physical variable factors may contribute to batting performance. This study examined the relationship between physical fitness or body composition and bat swing speed in female baseball players. Thirty-two Japanese female professional baseball players (21.9 ± 3.2 years) participated in this study. Height, body mass, lean body mass (upper-limb, trunk, lower-limb, and whole body), grip strength, back strength, knee extension strength, hamstring extensibility, vertical jump height, reaction time, and bat swing speed were measured at preseason. Body mass index was calculated by dividing weight by height squared. Vertical jump index was calculated by multiplying the vertical jump height by weight. Lean body mass showed significant positive correlations with bat swing speed [upper-limb (r = 0.415), trunk (r = 0.390), lower-limb (r = 0.376), and whole body (r = 0.408): P < 0.05]. Similarly, age (r = 0.537:P = 0.002), knee (extension strength (r = 0.415:P = 0.018), and vertical jump index (r = 0.442:P = 0.013) were significantly correlated with bat swing speed. When partial correlation analysis was performed with age as control variable, these correlations were found to become weaker and insignificant. Vertical jump index, however, showed the highest partial correlation of 0.359 (P = 0.052), which is close to critical value of significance but did not reach the significant level. This study showed that skeletal muscle mass, lower-limb strength, lower-limb muscle power, and age were related to bat swing speed in female baseball players. Age can be interpreted as a term of competitive and training experiences, which has both positive (e.g., improvement of performance skill) and negative (e. g., increase in injury risk) aspects for players. However, this study cannot clearly conclude a relationship between age and bat swing speed. Improvement of body composition and physical function may positively affect batting performance and thus hitting performance in women baseball players.
著者
柘植 秀樹 久世 伊知郎 藤井 一馬
出版者
日本海水学会
雑誌
日本海水学会誌 (ISSN:03694550)
巻号頁・発行日
vol.58, no.6, pp.579-584, 2004 (Released:2013-02-19)
参考文献数
6
被引用文献数
1

現在, リチウムイオン電池などの原料として炭酸リチウムに対する需要は大きい. 本研究では海水から得られるリチウム濃縮液と工場の排ガス中に含まれる二酸化炭素より炭酸リチウムを生成させる反応晶析についての基礎研究を行った. 反応晶析にはMSMPR型晶析装置を用い, 原料である水酸化リチウム初濃度, 反応温度, 撹拌回転数などの操作因子が炭酸リチウムの核発生速度, 結晶成長速度, 懸濁密度, 平均粒径などの晶析特性に及ぼす影響について検討した. 本実験範囲においては, 原料初濃度, 反応温度を増大させ, 撹拌回転数を減少させると核発生速度は増加した. また結晶成長速度は, 撹拌回転数を減少, 反応温度を増大させることで若干増加した. 懸濁密度は核発生速度と同様の操作因子で, また平均粒径は結晶成長速度と同様の操作因子で増加させることができた.