著者
山田 健一 石井 祐次 武田 知起 黒木 廣明 三苫 千景 内 博史 古江 増隆 山田 英之
出版者
福岡医学会
雑誌
福岡医学雑誌 = Fukuoka acta medica (ISSN:0016254X)
巻号頁・発行日
vol.106, no.5, pp.169-175, 2015-05-25

The effect of cynaropicrin that is the major component of an edible plant, artichoke (Cynarascolymus) on 2,3,4,7,8-pentachlorodibenzofuran (PenCDF)-induced toxicity in mice was studied. We evaluated the effect of cynaropicrin on the wasting syndrome and oxidative stress elicited by PenCDF. However, the PenCDF dose-response relationship on the wasting syndrome has been superficial. Therefore, we determined the dose which causes wasting syndrome in C57BL/6J m ice, a responsive strain to dioxins. Since 2,3,7,8-tetrachlorodibenzo-p-dioxin (0.1 mg/kg, p.o.) induces hepatic ethoxyresorfin O-deethylase (EROD) activity in mice, we set the doses of PenCDF at 0.3, 1.0, 3.0, 5.0 and 10 mg/kg (once, p.o.) on the basis of its toxic-eqivalency factor (0.3). The wasting syndrome was evaluated by measuring the daily changes of body weight. Thiobarbituric acid-reactive substances were used as an index of oxidative stress. Of PenCDF doses examined, wasting syndrome and oxidative stress took place most markedly in 5 mg/kg. In disagreement with this, EROD activity which is the marker of the aryl hydrocarbon receptor-dependent induction of cytochrome P450 1a1 was elevated most abundantly at 0.3 mg/kg. Then, we examined the effect of cynaropicrin on the wasting syndrome and oxidative stress provoked by PenCDF at 5 mg/kg. However, this compound up to 20 mg/kg (p.o.) did not attenuate PenCDF-induced wasting syndrome. On the contray, PenCDF-induced oxidateive stress was suppressed by cynaropicrin at the highest dose (20 mg/kg), although EROD activity was increased rather than reduced by cynaropicrin at lower doses. Thus, it is suggested that cynaropicrin has an ability to reduce oxidative stress caused by PenCDF.
著者
吉原 賢二
出版者
一般社団法人 日本原子力学会
雑誌
日本原子力学会誌 (ISSN:00047120)
巻号頁・発行日
vol.25, no.4, pp.239-243, 1983-04-30 (Released:2009-04-21)
参考文献数
11
著者
柴崎 一雄 大谷 史郎 平井 輝夫 鈴木 元吉
出版者
Japanese Society for Food Science and Technology
雑誌
日本食品工業学会誌 (ISSN:00290394)
巻号頁・発行日
vol.11, no.12, pp.521-530, 1964

食品を凍結あるいは凍結乾燥した場合の挙動を明らかにする目的で,本報ではまずモデル食品をつくり,凍結温度の検討を行なった。モデル食品は合成スポンジ(ソフラン)を担体として,ブドウ糖,食塩およびゼラチンの単独または,これらの2成分,3成分混合水溶液を含ませたものを用いて,溶液のままで外部から冷却(静的凍結)したものを対照としながら,自己凍結した場合の凍結温度に及ぼす以上の各成分の影響を検討した。
著者
仁木 勝治
出版者
立正大学文学部
雑誌
立正大学文学部研究紀要 (ISSN:09114378)
巻号頁・発行日
no.2, pp.33_a-13_a, 1986-03-20

I deal with the parallelism of the titles and the symbols between The Scarlet Letter by Nathaniel Hawthorne and The Sound and the Fury, William Faulkner in this paper. These works are constructed by the mental pictures of them. In this paper, first, I will examine their titles' meaning as the mental pictures, and then, will examine the fact of both writers having used "shadow, " "light, " "flower" and "weed" as symbols of "death, " "life, " "innocence" and "evil" in two works. As the problem of the symbols, first, I will point out the shadow as a symbol of death. It is associated with Dimmesdale, and can be find even in Hester who is struggling against her fate. This kind of shadow is closely associated with Quentin and even Benjy, too. In the beginning of Chapter two, Quentin is possessed of time as soon as he wakes in the morning, and absorbed in relation with the time and shadows that appear on the curtains, and then, he begins to make preparations for suicide. The shadow and his death present us important association. Second, I will consider about the light that makes a contrast with the shadow is found in the behaviors of Pearl and Benjy. In the forest, when Hester comes nigh on the sunlight, it withdraws itself from her, but it is caught by Pearl. Even in the forest where Hester and Dimmesdale commit a moral sin, Pearl seems to be shining "like a bright-apparelled vision, in a sunbeam." The light is very significant for Benjy as well as Pearl. Benjy stops crying when "Dilsey opens the fire-door and draw a chair up in front of it, " and touching Caddy's "Cold bright face, " "she smelled like trees" for him. Third, we can find one more similarity between Pearl and Benjy. It is an innocence. Each innocence is used as a contrast with sin being caused by sexual corruption. They take the rebellious manners for sinners or people who are about to commit sin with their puritan innocence. Benjy is closely associated with flowers like innocent Pearl is connected with rose as well as anemone and columbine. Fourth, I will examine the association with the evil and the weeds through the manners of Chillingworth and Jason. Chillingworth, an avatar of evil, finds "a dark, flabby leaf" that is "growing on a grave, " and tries to use it for the mental disease of Dimmesdale, and egoistic Jason gets "beggar lice and twigs and stuff all over" him, and has his hand on a bunch of poison oak, while he follows Miss Quentin who has run away with the men wearing a red tie. I have tried to examine the parallelism of symbols between The Scarlet Letter and The Sound and the Fury. This is not to be a study of Hawthorne's influence on Faulkner, but of symbols that are reflected in the works of these nineteenth-century New Englander and twentieth-century Southerner. I am sure that the parallelism of these symbols suggests that careful thought of each writing might throw light on that of the other.
著者
榎本 正雄 榎本 真 中島 彬
出版者
JAPAN SOCIETY OF PHOTOGRAMMETRY AND REMOTE SENSING
雑誌
写真測量 (ISSN:05494451)
巻号頁・発行日
vol.11, no.1, pp.21-26, 1972-04-25 (Released:2010-03-19)

In the designated district to the Matsumoto Sabo Construction Work Office, Ministry of Construction, there are many mountain streams having been troubled by the rucky mudflow damages.To investigate the cause of the rocky mudflow, many experiments together with the actual prevention works for the rocky mudflow have been done by the members belonged to this office.This report introduces briefly the general view of the organization and methods on the rucky mudflow investigation in our office.
著者
宮越 英紀
出版者
公益社団法人 砂防学会
雑誌
砂防学会誌 (ISSN:02868385)
巻号頁・発行日
vol.38, no.2, pp.28-30_2, 1985-07-20 (Released:2010-04-30)
参考文献数
3