著者
秋山 岑生
出版者
日経BP社
雑誌
日経ビジネス (ISSN:00290491)
巻号頁・発行日
no.851, pp.62-64, 1996-07-29

かつてはサンリオの子会社で商業用ロボットの開発を続け,人間型,恐竜型ロボットの製作では,世界のトップクラス。その後,社長を解任され,57歳で退社して新会社を設立。裸一貫から,販売用の人間型ロボットを作り始めた。「死ぬまで作り続けたい」とロボット作りに執念を燃やす。東京・池袋のボウリング場。来場客に,「乗りが悪いよ。
著者
Kiichiro Teruya Yuki Myojin-Maekawa Fumio Shimamoto Hiromitsu Watanabe Noboru Nakamichi Koichiro Tokumaru Sennosuke Tokumaru Sanetaka Shirahata
出版者
公益社団法人日本薬学会
雑誌
Biological and Pharmaceutical Bulletin (ISSN:09186158)
巻号頁・発行日
vol.36, no.3, pp.352-359, 2013-03-01 (Released:2013-03-01)
参考文献数
49
被引用文献数
3 10

Gastrointestinal damage associated with radiation therapy is currently an inevitable outcome. The protective effect of Kefir was assessed for its usefulness against radiation-induced gastrointestinal damage. A Kefir supernatant was diluted by 2- or 10-fold and administered for 1 week prior to 8 Gray (Gy) X-ray irradiation at a dose rate of 2 Gy/min, with an additional 15 d of administration post-irradiation. The survival rate of control mice with normal drinking water dropped to 70% on days 4 through 9 post-irradiation. On the other hand, 100% of mice in the 10- and 2-fold-diluted Kefir groups survived up to day 9 post-irradiation (p<0.05 and p<0.01, respectively). Examinations for crypt regeneration against 8, 10 and 12 Gy irradiation at a dose rate of 4 Gy/min revealed that the crypt number was significantly increased in the mice administered both diluted Kefir solutions (p<0.01 for each). Histological and immunohistochemical examinations revealed that the diluted Kefir solutions protected the crypts from radiation, and promoted crypt regeneration. In addition, lyophilized Kefir powder was found to significantly recover the testis weights (p<0.05), but had no effects on the body and spleen weights, after 8 Gy irradiation. These findings suggest that Kefir could be a promising candidate as a radiation-protective agent.
著者
井上 清 小林 唯男 谷口 薫
出版者
日本質量分析学会
雑誌
Journal of the Mass Spectrometry Society of Japan (ISSN:13408097)
巻号頁・発行日
vol.14, no.5, pp.265-274, 1966-12-25 (Released:2010-06-28)
参考文献数
4

A fundamental study was performed on the mass spectrometric determination of the ratios of uranium and fission products in the uranium dioxide specimen irradiated in the nuclear reactor. Mass spectrometer used in this experiment was a 90° sector type with a 350 mm radius of curvature, made by Hitachi, Ltd. In the period of the experiment, this spectrometer was equipped with a thermal-ionization source. The specimen dissolved in nitric acid was pipetted and evaporated to dryness on a filament, and then was analysed in the single filament arrangement. From the results it has been found that: (1)By isotopic analysis of uranium, the contribution to burnup of the specimen by fission of U235was determined as 4, 370 MWD/T. The loss of U235in neutron capture reaction during inadiation was corrected by the ratio of U236to U235. (2)The burnup of the specimen can be determined from the amount of a fission product formed during irradiation. Because of known contribution of the burnup by fission of U235mentioned above, the contribution of burnup of the specimen by fission of Pu239 might be determined by excessive formation of fission product. As the number of fissions of Pu239 was estimated, the burnup of the specimen was calculated as approximately 7, 980 MWD/T. (3)Experience with the mass spectrometric analysis was obtained for the radioactive specimen. The noticeable phenomenon was the increase in the emissivity of ion current at relatively law heating current through filament under the existence of beta-rays emitter.
著者
浅岡 顕 野田 利弘 山田 英司 金田 一広 中野 正樹
出版者
公益社団法人地盤工学会
雑誌
地盤工学会論文報告集 (ISSN:13417452)
巻号頁・発行日
vol.42, no.5, pp.47-57, 2002-10-15
参考文献数
16
被引用文献数
16

In critical state soil mechanics, the volume change behavior of soils has typically been analyzed based upon conventional "e-logp' relationships". However, compaction/densification of loose sand, for example, can sometimes occur even without any significant increase of mean effective stresses. This study presents a model which considers the fact that volume change can occur due to decay/collapse of the structure of soils. Taking into consideration the differences between clay and sand, this study models super-subloading surfaces together with rotational hardening using the modified Cam-clay model. The effects of decay of the soil structure, loss of overconsolidation and evolution of anisotropy are mutually discussed concerning their relationship with ongoing plastic deformation. Fundamental constitutive model responses are illustrated in the present study particularly for "compaction" of sand. Repeated application of low-level shear stress upon loose sand yields a huge amount of volume compression, which is due to the rapid collapse of the initial soil structure. Repetition of the loading also results in a rapid increase of the overconsolidation ratio. Drained and undrained shear behavior of the sand naturally changes remarkably along this densification/compaction procedure, which is also consistently predicted using a single set of soil parameters. Elasto-plastic behavior of the same sand at various densities is thus totally described in the present study in a single the-oretical framework based on soil parameters independent of density.
著者
金田 一弘
出版者
大阪歯科大学
雑誌
若手研究(B)
巻号頁・発行日
2011

虚血プレコンディショニングではNOSの刺激作用を有するブラディキニンB2受容体の関与が明らかとなっている.エタノールプレコンディショニングにおいてブラディキニンB2受容体の関与は報告されていない.エタノールの心筋保護効果にブラディキニンの関与をブラディキニンB2受容体の阻害薬であるHOE-140を用いて,エタノールプレコンディショニング効果が消失するか否か,またNOの産生量を測定した.
著者
森 大吉郎 橋元 保雄 中田 篤 上杉 国憲 西田 稔夫 福沢 清
出版者
宇宙航空研究開発機構
雑誌
宇宙科学研究所報告 (ISSN:02852853)
巻号頁・発行日
vol.17, pp.1-69, 1984-02
被引用文献数
1

Mu rocket assembly and launch system was renewed on the same place where the former one had stood on. After breaking down of the former one, the foundation work started on April 1981,and all of the construction finished on August 1982. This system consists of a rocket assembly tower and a launcher. The assembly tower is a steel-framed truss structure building which has 11 floors and contains cranes, big doors, and movable floors necessary to bring in, assemble, and check out the Mu rocket. This tower is 43m high, 18m wide, 13m deep, and 700 ton in weight. The launcher is 300 ton in weight and made up of a boom structure and guide rails on which a rocket slides away. This launcher can revolve by bogies on a circular rail from the assembly tower toward the launching point. A flame deflector cooled by water is automatically installed to the launcher during its revolution. On February 20 1983,M-3S-3 rocket was successfully launced as the first satellite launch using this system.
著者
Imari Mimura Tetsuhiro Tanaka Youichiro Wada Tatsuhiko Kodama Masaomi Nangaku
出版者
(公社)日本薬理学会
雑誌
Journal of Pharmacological Sciences (ISSN:13478613)
巻号頁・発行日
vol.115, no.4, pp.453-458, 2011 (Released:2011-04-15)
参考文献数
41
被引用文献数
18 29

The hypoxia response regulated primarily by hypoxia-inducible factor (HIF) influences metabolism, cell survival, and angiogenesis to maintain biological homeostasis. In addition to the traditional transcriptional regulation by HIF, recent studies have shown that epigenetic modulation such as histone methylation, acetylation, and DNA methylation could change the regulation of the response to hypoxia. Eukaryotic chromatin is known to be modified by multiple post-translational histone methylation and demethylation, which result in the chromatin conformation change to adapt to hypoxic stimuli. Interestingly, some of the histone demethylase enzymes, which have the Jumonji domain–containing family, require oxygen to function and are induced by hypoxia in an HIF-1–dependent manner. Recent studies have demonstrated that histone modifiers play important roles in the hypoxic environment such as that in cancer cells and that they may become new therapeutic targets for cancer patients. It may lead to finding a new therapy for cancer to clarify a new epigenetic mechanism by HIF and histone demethylase such as JMJD1A (KDM3A) under hypoxia.
著者
定本 裕明 飯村 康二 本名 俊正 山本 定博
出版者
一般社団法人日本土壌肥料学会
雑誌
日本土壌肥料學雜誌 (ISSN:00290610)
巻号頁・発行日
vol.65, no.6, pp.645-653, 1994-12-05
被引用文献数
26

McLAREN らの方法とこれを一部改良した方法とを比較検討し,汚染,非汚染各種土壌中の銅,亜鉛,カドミウムの形態分布の特性を調べた.結果の概要は次のとおりである.1)有機結合態の抽出方法を検討した結果,原法の0.1M ピロリン産カリウム抽出法では,有機物がほとんど含まれていない黒ボク土下層土と表層土と大差ない抽出量が得られたが,6%過酸化水素で有機物を分解した後,2.5%酢酸で抽出する方法では,下層土における抽出量が著しく低下した.遊離酸化物吸蔵態の抽出については,原法の UV-酸性シュウ酸アンモニウム抽出では赤黄色土で遊離酸化物の還元,抽出が不十分であったが,アスコルビン酸-酸性シュウ酸アンモニウム抽出によれば他の土壌はもちろん,とくに赤黄色土において遊離酸化物吸蔵態の重金属抽出量が著しく増加した. 2)無機結合態や有機結合態の抽出に用いた2.5%酢酸は,ゲータイトおよびギブサイトに吸着された重金属をほぼ全量抽出した. 3)非汚染土壌中において銅は,全体の約半分が残渣が全体の約6割から7割を占めており,続いて遊離酸化物吸蔵態の割合が高い.カドミウムは,同夜亜鉛で少ない交換態,,無機結合態が比較的多く,土壌中のカドミウムの量が植物に吸収されやすい形で存在していることを示した. 4)汚染土壌では各重金属とも非汚染土壌より交換態,無機結合態等の植物に吸収されやすい形態が多く,特に汚染水田のカドミウムは交換態の割合が非常に高く,わずかな汚染でも植物中のカドミウム濃度を増加させる危険性があることが示された.
著者
長堀 金造
出版者
岡山大学農学部
雑誌
岡山大学農学部学術報告 (ISSN:04740254)
巻号頁・発行日
no.31, pp.45-51, 1968-03

水田からの浸透水は反復利用されるもので局地的な減水深とかんがい面積から算定した水量をもって広域の用水量とすることは,過剰に用水量をみこむことになるので,水資源の有効利用の観点からいっても好ましくない. ゆえに広地域を対象にしたかんがい計画を樹立する際には水収支によって用水量を決定することが合理的な方法といえる. 以上の観点から,低平地水田地帯の水収支による用水量の実態調査を行なった結果,次の諸点が明らかとなった. 1)まず,水収支式は (Q2-Q1)+(G2-G1)+en,+⊿S=0 上式中,(G2-G1)+en,tn+⊿Sが広域水田の消費水量となる. 一般に低平地では(G2-G1)≒0 水量の安定した期間であれば⊿S≒0とみなせるから,本地域のような所では消費水量はen,tnと考えられる. 2)一方,モデル地区内の流量実測データより水収支計算によって求めた消費水量は,Iの期間(7月18日~22日)では水深になおして,11.8mmday,Iの期間(8月10日~14日)では11.0mm/day,Ⅲの期間(9月7日~11日)では7.1mm/dayの値となった. 3)他方,蒸発計蒸発量を基にして求めた蒸発散量 en,tn の結果はI期間が12.04mm/day,Ⅱ期間が11.62mm/day,Ⅲ期間が8.42mm/day,の結果となり,計器蒸発量を基にして算定した方が,3期問とも若干,en,tnが実測水収支の結果より値が大きい. しかし,それらの差は極めて小さい. 4)従って,本地域のように低平地水田地帯の消費水量はen,tnによるものであり,従ってG2-G1≒0⊿S≒0とみなせるものと考えられる. 5)以上から,本地域における消費水量は,en,tn程度のものでありながら,かんがい水量と排水量の両者が極めて多いことは注目すべきで,かんがい排水量を一適正化することが望まれる. 6)次に本地域の用水の反復利用量を検討してみたところ,平均的にみて,およそ5~6mm/dayの水量が反復利用されていることが明らかとなった. おわりに,本論文は昭和37年,著者が京大在職中に行なった巨椋池干拓地,かんがい排水の実態調査研究の一部であることを付記し,御援助いただいた巨椋池土地改良区の関係各位に謝意を表する次第である。
著者
梶川 正弘 卜蔵 建治
出版者
日本自然災害学会
雑誌
自然災害科学 (ISSN:02866021)
巻号頁・発行日
vol.8, no.2, pp.46-56, 1989-09-30

A severe disaster was caused by gusts and hailfalls in Aomori and Miyagi Prefectures on September 7,1986. This report outlines meteorological conditions and damages in relation to the hailstorms. The followings are the main results. 1) The gusts accompanied by hailfalls were brought about by a group of cumulonimbi related mainly to the unstable stratification by advection of upper cold air. 2) The damage due to gust in Aomori Prefecture was the drop of apple fruits and the lodging of apple trees by a tornado. 3) Most of the damages in Miyagi Prefecture were the injury of heads of rice plants by hailfalls.

1 0 0 0 OA 官報

著者
大蔵省印刷局 [編]
出版者
日本マイクロ写真
巻号頁・発行日
vol.1938年12月22日, 1938-12-22

1 0 0 0 OA 官報

著者
大蔵省印刷局 [編]
出版者
日本マイクロ写真
巻号頁・発行日
vol.1924年03月18日, 1924-03-18