著者
伊勢 孝之 高木 恵理 岩瀬 俊 楠瀬 賢也 山口 浩司 八木 秀介 山田 博胤 添木 武 若槻 哲三 佐田 政隆
出版者
一般社団法人 日本内科学会
雑誌
日本内科学会雑誌 (ISSN:00215384)
巻号頁・発行日
vol.104, no.6, pp.1175-1179, 2015-06-10 (Released:2016-06-10)
参考文献数
8
被引用文献数
1

心臓サルコイドーシスの標準的治療はステロイドであるが,ステロイドを投与中であっても再燃を認めることも多く,またステロイドの多岐にわたる副作用も問題となることが多い.症例は70歳代,女性.心臓サルコイドーシスの診断でプレドニンを維持量5 mg/日で加療されていた.定期検査で施行した心電図で陰性T波,前壁心尖部に新規の左室壁運動異常を認めた.FDG-PET,Gaシンチグラフィーで壁運動異常部位に一致して集積を認め,心臓サルコイドーシスの再燃と判断した.本症例では,ステロイドの副作用として糖尿病,肥満,白内障などを認めており,ステロイド増量が躊躇され,メトトレキサートの併用を開始した.メトトレキサート開始後,特に副作用を認めず,心電図ならびに左室壁運動異常の改善が認められた.ステロイド投与で再燃を認める心臓サルコイドーシス症例にはメトトレキサート併用も考慮すべきであると考えられた.
著者
MinJoon Ji
出版者
理学療法科学学会
雑誌
Journal of Physical Therapy Science (ISSN:09155287)
巻号頁・発行日
vol.28, no.5, pp.1544-1546, 2016 (Released:2016-05-31)
参考文献数
14
被引用文献数
1 19

[Purpose] The purpose of the present study was to examine the types of injuries associated with mixed martial arts and their location in order to provide substantial information to help reduce the risk of these injuries during mixed martial arts. [Subjects and Methods] Data were collected from 455 mixed martial arts athletes who practiced mixed martial arts or who participated in mixed martial arts competitions in the Seoul Metropolitan City and Gyeongnam Province of Korea between June 3, 2015, and November 6, 2015. Questionnaires were used to collect the data. The convenience sampling method was used, based on the non-probability sampling extraction method. [Results] The arm, neck, and head were the most frequent locations of the injuries; and lacerations, concussions, and contusions were the most frequently diagnosed types of injuries in the mixed martial arts athletes in this study. [Conclusion] Reducing the risk of injury by establishing an alert system and preventing critical injuries by incorporating safety measures are important.
著者
森 和也 陳 玳〓 西谷 弘信
出版者
一般社団法人 日本機械学会
雑誌
日本機械学会論文集 A編 (ISSN:03875008)
巻号頁・発行日
vol.57, no.544, pp.2987-2991, 1991-12-25 (Released:2008-02-21)
参考文献数
8

The authers have developed a method for satisfying resultant boundary conditions on each divided boundary by discrete point forces. This method stands high accuracy and short calculating time at the same time. However, to obtain highly accurate solutions, it is necessary to put the point forces at the optimum locations. In this paper, the optimum location of point forces were obtained through several problems in 2D or 3D. The optimum location, that is, the optimum ratio of devided boundary length to distance between point force and boundary is 0.5∼0.7 in the case of notch problems and is 1.5 in the case of crack problems.
著者
岩崎 成夫
出版者
The Society of Synthetic Organic Chemistry, Japan
雑誌
有機合成化学協会誌 (ISSN:00379980)
巻号頁・発行日
vol.49, no.10, pp.892-901, 1991 (Released:2009-11-16)
参考文献数
36
被引用文献数
1 3

CLC部位に作用する化合物の構造要因は立体化学も含めて比較的単純で, STG (3) やPDT (4) のような複雑さを要しないように見える。事実, 多数の合成剤も作られている。しかし, これら薬剤の対象であるカビ, 寄生虫などに耐性が出やすく, A.nidulansのBZ剤耐性株で解析されたβ-TNの変異点が6箇所にも及ぶという事実とよく一致している。一方, 現在までに知られているVLB-MAY部位に作用する化合物は, 皆多数のキラル中心を持つ複雑な構造で, 今までは構造の部分修飾による活性の変化が調べられていた。今後は, 単純化した必須の構造要因を明らかにし, 分子認識機構を解明していくことも期待したい。この部位を標的とする薬剤の医薬・農薬としての応用では, VLB-MAY部位でのβ-TNの変異が起こりにくいことから, 耐性は出にくいという利点が予想される。以上述べてきたように, TNとこれに結合してその機能を阻害する化合物との間の相互作用について, 多くの事実は明らかになってきたが, 依然として, これら阻害剤がTNの3次元構造の何処にどのように結合しているのかは全く分っていない。そのために, 阻害剤を非可逆的に結合する (アフィニティラベル) 試みも続けられている。また, 何時か, TN-リガンド複合体の結晶解析も可能となることを願っている。
著者
Haiyan Wan Zhao Hu Jinhong Wang Shimei Zhang Xiangdong Yang Tao Peng
出版者
一般社団法人 日本内科学会
雑誌
Internal Medicine (ISSN:09182918)
巻号頁・発行日
vol.55, no.11, pp.1433-1437, 2016-06-01 (Released:2016-06-01)
参考文献数
13
被引用文献数
8

Objective There are many adverse reactions due to clindamycin, but kidney diseases (acute kidney injury, AKI) are uncommon. However, in recent years, the rate of clindamycin-induced kidney diseases has increased. We analyzed 50 patients with clindamycin-induced kidney diseases retrospectively, and investigated the characteristics of these kidney diseases in order to provide a reference for rational clinical drug use and to reduce drug-induced organ damage. Methods We investigated 50 patients diagnosed with clindamycin-induced kidney diseases retrospectively at the Department of Nephrology, Shandong University Qilu Hospital, from January 2009 to December 2013. The parameters included in our study were age, sex, clinical manifestations, efficacy and prognosis. Results All patients were diagnosed with clindamycin-induced kidney diseases within 48 hours of the application of clindamycin at 1.0-2.0 g/day. The patients included 29 women and 21 men. Most of the enrolled patients were 20-59 years old. Fifty-one patients were diagnosed with AKI stage 3 upon admission. Thirty-three had episodes of gross hematuria, but fever, skin rash and eosinophilia were rare. Urine analysis revealed mild proteinuria and severe tubular dysfunction. In the majority of patients, AKI was severe and required renal replacement therapy, but renal function in all patients had recovered significantly two months after discharge. Conclusion Clindamycin-induced AKI is largely reversible and is associated with episodes of gross hematuria. Clinicians should use clindamycin rationally and reduce the incidence of adverse reactions.
著者
Saran KEERATIHATTAYAKORN Satoshi YAMADA Shigeru TADANO
出版者
一般社団法人 日本機械学会
雑誌
Journal of Biomechanical Science and Engineering (ISSN:18809863)
巻号頁・発行日
pp.15-00423, (Released:2015-09-07)
参考文献数
27
被引用文献数
1 1

The authors proposed an electromyography computed tomography (EMG-CT) method to measure the distribution of muscle activity in the forearm using surface EMG signals from multiple surface electrodes. The present study is to develop a method to estimate muscle stress, i.e., force generated during contraction per unit area in the whole cross-section of the forearm based on EMG-CT. While three subjects performed hand gripping trials using three hand grip devices, EMG signals around the forearm were measured using EMG-CT. An EMG conduction model of the forearm was constructed using an outline geometry of the subjects' forearm which was measured with a handy 3D scanner. The stress of muscle was calculated from the relationship between gripping force and total muscle activity. As a result, the distribution of muscle stress in the forearm during hand gripping was visualized in a tomographic image. It was clear that the stress was concentrated in the flexor digitorum superficialis, flexor digitorum profundus, flexor carpi radialis, and extensor digitorum communis region. The maximum stress in the forearm muscles increased from 0.08 ± 0.01 to 0.18 ± 0.02 MPa when gripping force increased from 77 to 242 N. This study provides a novel method of measuring muscle stress in forearm.
著者
岡部 和代 黒川 隆夫
出版者
一般社団法人 日本繊維製品消費科学会
雑誌
繊維製品消費科学 (ISSN:00372072)
巻号頁・発行日
vol.45, no.6, pp.416-424, 2004-06-25 (Released:2010-09-30)
参考文献数
13

ブラジャー内の乳房の3次元偏位特性はほとんど知られていないが, 機能的なブラジャーをデザインするためには不可欠である.本研究では, 3次元計測器で測定したブラジャー着用前後の左胸25点の座標値から位置変化を求めた.被験者は22~24歳の成人女性7名である.実験試料は3種類の市販のブラジャーで, Type1は下カップにワイヤーのあるフルカップブラジャー, Type2はボーン部に柔らかいワイヤーがあるフルカップブラジャー, そしてType3はスポーツブラジャーである.実験試料は, ブラジャーのカップ部の装飾を衣服圧に影響を及ぼさないと確認後に削除して用いた.まず, 測定した座標点の偏位量を算出しTypeの違いを明らかにした.Typeの違いは垂直方向ではなく, 左右方向の偏位量の大小や, 前後方向の偏位に見られた.次に測定点の違いが, 乳房の柔らかい前腋点方向や体側側の領域の偏位量が正中線側より顕著であること, 正中線側では内輪の偏位量が最大を示すが, 体側側では外輪であることを明らかにした.偏位量は乳房形状や硬さの特性に依存する面が大きく個人差が認められた.今後は被験者のパラメータを類型化して検討を行いたい.
著者
Hideo Okamura Christopher J. McLeod Christopher V. DeSimone Tracy L. Webster Crystal R. Bonnichsen Martha Grogan Sabrina D. Phillips Heidi M. Connolly Naser M. Ammash Carole A. Warnes Paul A. Friedman
出版者
日本循環器学会
雑誌
Circulation Journal (ISSN:13469843)
巻号頁・発行日
vol.80, no.6, pp.1328-1335, 2016-05-25 (Released:2016-05-25)
参考文献数
37
被引用文献数
1 30

Background:The subcutaneous implantable cardioverter defibrillator (S-ICD) provides an attractive option for patients with congenital heart disease (CHD) in whom a transvenous defibrillator is contraindicated. Given the unusual cardiac anatomy and repolarization strain, the surface electrocardiogram (ECG) is frequently abnormal, potentially increasing the screen failure rate.Methods and Results:We prospectively screened 100 adult CHD patients regardless of the presence of clinical indication for ICD utilizing a standard left sternal lead placement, as well as a right parasternal position. Baseline patient and 12-lead ECG characteristics were examined to assess for predictors of screen failure. Average patient age was 48±14 years, average QRS duration was 134±37 ms, and 13 patients were pacemaker dependent. Using the standard left parasternal electrode position, 21 patients failed screening. Of these 21 patients with screen failure, 9 passed screening with the use of right parasternal electrode positioning, reducing screening failure rate from 21% to 12%. QT interval and inverted T wave anywhere in V2–V6 leads were found to be independent predictors of left parasternal screening failure (P=0.01 and P=0.04, respectively).Conclusions:Utilization of both left and right parasternal screening should be used in evaluation of CHD patients for S-ICD eligibility. ECG repolarization characteristics were also identified as novel predictors of screening failure in this group. (Circ J 2016; 80: 1328–1335)
著者
村松 一生
出版者
炭素材料学会
雑誌
炭素 (ISSN:03715345)
巻号頁・発行日
vol.2013, no.256, pp.60-66, 2013-01-15 (Released:2013-02-15)
参考文献数
16
被引用文献数
3 9
著者
Yuichiro Karasawa Shogo Oshima Tomonori Nomoto Taro Toyota Masanori Fujinami
出版者
(社)日本化学会
雑誌
Chemistry Letters (ISSN:03667022)
巻号頁・発行日
vol.43, no.7, pp.1002-1004, 2014-07-05 (Released:2014-07-05)
参考文献数
20
被引用文献数
31

The distribution of surface tension on the front and rear sides of a camphor boat continuously moving on an aqueous-phase camphor solution was observed by the time-resolved quasi-elastic laser scattering method. The uniform motion of the boat was induced by a difference in the surface tension between the front and rear sides. A surface-tension gradient developed along the rear side, resulting in Marangoni convection that decelerated the boat.
著者
部家 彰 松尾 直人
出版者
一般社団法人 表面技術協会
雑誌
表面技術 (ISSN:09151869)
巻号頁・発行日
vol.58, no.12, pp.836-836, 2007 (Released:2008-08-01)
参考文献数
14

The surface properties of a plastic substrate were changed using a novel surface treatment called atomic hydrogen annealing (AHA). In this method, a plastic substrate was exposed to atomic hydrogen generated by cracking hydrogen molecules on heated tungsten wire. Surface roughness was increased, and O atoms and halogen elements (F and Cl) were selectively etched by AHA. The surface modification of the PEN substrate affects the surface property of the SiNx film. Adhesion between the SiNx film and the PEN substrate in the SiNx film/PEN substrate prepared by Cat-CVD shows excellent properties.
著者
Yasutaka Omori Hiroaki Wakamatsu Atsuyuki Sorimachi Tetsuo Ishikawa
出版者
福島医学会
雑誌
FUKUSHIMA JOURNAL OF MEDICAL SCIENCE (ISSN:00162590)
巻号頁・発行日
vol.62, no.1, pp.1-17, 2016 (Released:2016-06-08)
参考文献数
49
被引用文献数
1 14

This study was conducted on the Fukushima Medical University (FMU) premises (in Fukushima City, Fukushima Prefecture) about four years after the Fukushima Daiichi Nuclear Power Plant accident. Its objectives were (1) to create a map of the ambient gamma dose rate (air-kerma rate) distribution, (2) to evaluate the air-kerma rate originating from natural radionuclides, and (3) to investigate the effects of snow cover on changes in the air-kerma rate. This man-borne survey revealed that the air-kerma rate varies widely, ranging from 0.038 μGy h-1 to 0.520 μGy h-1, and is higher on grass than on the other investigated surface types, such as soil, asphalt, and bricks. In this area, the mean air-kerma rate from natural radiation was evaluated to be 0.03 ± 0.01 μGy h-1, which is close to 0.04 μGy h-1, which was measured in central Fukushima City by a local authority.Furthermore, snowfall was found to reduce the air-kerma rate by 5%-30%. This reduction was attributed to attenuation of the primary radiation while passing through the snow cover, and the measured contribution of scattered radiation to the air-kerma rate reduction was small. The reduction rate was found to depend on the initial snow depth but to maintain a similar value for a couple of days, after the snow had partially melted and its depth had decreased. Finally, analysis of the daily dose due to external exposure received on the FMU premises revealed that no further health effects due to chronic radiation exposure at this site are to be expected.
著者
三宅 洋一 中口 俊哉
出版者
一般社団法人 電子情報通信学会
雑誌
電子情報通信学会 基礎・境界ソサイエティ Fundamentals Review (ISSN:18820875)
巻号頁・発行日
vol.2, no.3, pp.3_29-3_37, 2009-01-01 (Released:2011-05-01)
参考文献数
18
被引用文献数
1

画像評価は銀塩写真,印刷,CRTテレビを中心に長い歴史を通して地道な研究が行われ,今日の高い画質を持つ多様なディジタル画像システムへと発展してきた.画質評価の研究は,主観評価と対応の良い物理評価パラメータを見いだす研究として行われてきたが,いまだに完全なる解明はなされていない.本稿では,銀塩写真,印刷,CRTに代表されるアナログ画像から最近のフラットパネルディスプレイやインクジェットプリンタに至る画質の問題を概観する.まず主観評価と客観評価の基礎から解説し,視覚特性と画質,更に高次な表現パラメータである質感について述べる.また画質と深く関連している疲労についての研究成果など,筆者の研究室で行っている研究を中心に概説する.
著者
河原 淳人 岩堀 太紀 山川 宏 佐藤 亨 山本 衛 橋口 浩之
出版者
一般社団法人 日本航空宇宙学会
雑誌
日本航空宇宙学会論文集 (ISSN:13446460)
巻号頁・発行日
vol.64, no.3, pp.189-199, 2016 (Released:2016-06-05)
参考文献数
18

Shape estimation of space debris is an important task in evaluating its trajectory evolution and collision probability with resident objects in space. This paper shows the magnitude and rotation of space debris can be estimated by investigating the Doppler shift with a Single Range Doppler Interferometry (SRDI) method. The theory of SRDI method is discussed and its usefulness is confirmed by numerical simulations. Furthermore, fluctuation of Doppler shift of known space debris were successfully observed by the MU radar of Kyoto University and the size and spin rate of some space debris were successfully estimated.
著者
山口 一男
出版者
日本社会学会
雑誌
社会学評論 (ISSN:00215414)
巻号頁・発行日
vol.50, no.2, pp.231-252, 1999-09-30 (Released:2009-10-19)
参考文献数
10
被引用文献数
2 2

本稿は潜在クラス分析と関連する回帰分析を用いて性別役割態度の潜在クラスと社会階層との関連について日本および米国の既婚女性を分析し結果を比較する。潜在クラスについては日本では「性別役割支持型」, 「性的平等支持・職業志向型」, 「性的平等支持・非職業志向型」の3クラス, 米国では「性別役割支持・両立否定型」, 「性別役割支持・両立肯定型」, 「性的平等支持型」の3クラスが存在する事を示し, 潜在クラスの割合が本人, 夫, 父親の階層属性にどう関連しているかを明らかにする。また「性別役割支持型」対「性的平等支持型」の割合比へのそれらの属性の影響を日米で比較する。最後に分析結果の理論的意味と今後の展望を議論する。
著者
松田 素二
出版者
日本アフリカ学会
雑誌
アフリカ研究 (ISSN:00654140)
巻号頁・発行日
vol.1983, no.23, pp.1-33, 1983-05-28 (Released:2010-04-30)
参考文献数
72
被引用文献数
1

African urban studies of Anthropology have their origin in one ideal model, the dyachronic detribalization model. This model assumes that African urbanization can be regarded as a gradual process of detribalization in consequence of direct contacts with heterogeneous and powerful Western cultures. In the 1950's, members of the Rhodes-Livingstone School such as Gluckman, Mitchell and Epstein advocated a new approach for African urban studies on the basis of their field researches of copperbelt towns in Northern Rhodesia (now Zambia). They criticized the detribalization model and put forward the situational approach, which emphasized synchronic social relations. According to this approach, the social relations of African rural-urban migrants are in some situations based on their traditional tribal norms but in others are based on urban norms. The situational approach is a very useful one because it highlights the migrants' personal strategy in situational selections. It cannot, however, explain the retribalization phenomenon which prevails in the African metropolises today. Those urban migrants who come from rural areas do not break away from tribal social relations but on the contrary reorganize these tribal relations in order to live a stable life in the urban environment. The situational approach cannot explain the paradox of the retention of tribal relations in a strikingly urban context.This paper tries to resolve the problems of retribalization by analysing a re-organization process of social relations by the Maragoli migrants from Kerongo village, Western Kenya in Kangemi, a poor housing area in Nairobi. Kangemi, located in the northwest area of the city, is an urban colony for the Maragoli migrants. We can observe an actual re-organization process of various kinds of social relations there. In order to elucidate this process, this paper adopts the following procedures.1. Firstly, several social situations, where social relations are developed and organized, are chosen from the daily life of the migrants from Kerongo village in Kangemi. This paper extracts empirically eight situations, namely, (1) securing the first accomodation, (2) seeking permanent employment, (3) borrowing or lending money, (4) borrowing or lending daily goods, (5) drinking beer or local alcohol, (6) exchanging messages and information with their home village, Kerongo, (7) participating in church activities, (8) carrying the body of a migrant back to the home village and preparing and performing a ritual of “ilisyoma” in Nairobi.2. Secondly, the forms of re-organizing social relations in each situation are examined. The forms can be sorted into two types, network type and group type. According to the former type, whenever they confront difficulties in some situations of their daily life, the migrants set up a kind of association to deal with the difficulties. When they do not form an association but extend their personal social networks, this form is called the group type.3. Thirdly, the principles of re-organizing social relations are verified in each situation. The clan-lineage principle, the village-home-boy principle and the urban neighbourhood-locality principle are presented here. Thus, the migrants from Kerongo village living in Kangemi re-organize their social relations by using different forms and different principles in each situation.4. Although most parts of these re-organization processes can be presented as retribalization phenomena, this paper pays much more attention to a process organized by the home-boy principle. The study fourthly examines how the home-boy principle, which has been developed recently in town, is embedded and reinterpreted in a traditional and dominant ideology of unilineal descent. In order to provide the home-boy principle with legitimacy in the framework of the ideology of unilineality, the Kerongo villagers have adopted two stages
著者
Mika YAMAZAKI Mai INOUE Katsuaki SUGIURA
出版者
公益社団法人 日本獣医学会
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
pp.16-0074, (Released:2016-06-03)

Data from 48,187 cats insured between April 2012 and March 2013 were analyzed using logistic regression analysis to determine the association of age, breed and sex with the occurrence of urinary disorders. The overall annual prevalence of urinary disorders was 12.2%. Using crossbreeds as the reference breed, Abyssinian cats had the highest odds of having urinary disorders with a ratio of 1.40 (95% confidence interval: 1.20–1.63), followed by Norwegian Forest Cats and Somalis. Male cats had higher odds of having urinary disorders with a ratio of 1.27 (1.20–1.35) over female cats. Older cats had higher odds of having urinary disorders than young cats.