著者
室井 みや 笠井 清登 植月 美希 管 心
出版者
日本認知心理学会
雑誌
認知心理学研究 (ISSN:13487264)
巻号頁・発行日
vol.4, no.2, pp.65-73, 2007-03-31 (Released:2010-10-13)
参考文献数
31
被引用文献数
1

ストループ課題および情動ストループ課題を用いて,統合失調症における情動的情報,非情動的情報に関する選択的注意機能について検討を行った.その結果,ストループ課題において,統合失調症者では不一致条件と中性条件の反応時間の違いは有意ではなかったが,統制群に比べて,不一致条件と中性条件の誤答率の違いは大きかったことから,無関連情報の処理を抑制する機能が低下していること,課題要求の保持が難しいことが示された.また,情動ストループ課題では,単語の種類による反応時間の違い,誤答率の違いは全体として有意ではなかったことから,情動的情報の認知機能障害は,情動的情報への注意バイアスによるものではなく,情動的情報に関する処理機能自体が低下しているためである可能性が示された.
著者
井村 修
出版者
公益社団法人 日本心理学会
雑誌
心理学研究 (ISSN:00215236)
巻号頁・発行日
vol.73, no.5, pp.383-390, 2002-12-25 (Released:2010-07-16)
参考文献数
18
被引用文献数
1

The purpose of the present study was to investigate the ability of schizophrenic patients to take another person's perspective. Two perspective taking tasks were examined: perceptual and affective perspective taking. Three groups participated in the study: 22 schizophrenics, 11 transient psychotic disorder [TPD] patients, and 20 normal students. Both schizophrenic and TPD patients scored significantly lower in the both perspective taking tasks than the normal controls. The affective perspective taking scores of the two patients groups were compared with those of six year-old children. Although schizophrenic and TPD patients were thought to be able to infer another's affective state correctly, they sometimes made errors in the task, because they failed to control for their own affect. Thus, their response tendency was different from the normal children of the age. The two patients groups appeared to have a common specific difficulty in inferring another's emotions.
著者
Katsumi ISHIOKA Yumi SUZUKI Kana TAJIMA Sumire OHTAKI Masahiro MIYABE Mariko TAKASAKI Akihiro MORI Yutaka MOMOTA Daigo AZAKAMI Toshinori SAKO
出版者
公益社団法人 日本獣医学会
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
vol.75, no.2, pp.173-177, 2013 (Released:2013-03-01)
参考文献数
15
被引用文献数
1 10

Monocyte chemoattractant protein-1 (MCP-1) is a member of the C-C family chemokines, which mobilizes monocytes from bone marrow to the site of inflammation. To evaluate the clinical utility of canine MCP-1 as a blood test item, we measured serum MCP-1 concentrations in normal and ill dogs. Reference interval of canine MCP-1 was established as 115.6–176.9 pg/ml. Serum MCP-1 concentrations increased in the dogs affected with neoplastic (518.0 ± 84.8 pg/ml), inflammatory (257.0 ± 42.5 pg/ml) or other diseases (360.3 ± 45.2 pg/ml). The results showed high sensitivity of MCP-1 to detect neoplasia and inflammation. Moreover, MCP-1 increased in some cases in which C-reactive protein didn’t increase. MCP-1 might be helpful as a screening blood test marker for detection of neoplasia and inflammation in dogs.
著者
Yusuke MURASE Satoru KONNAI Naftaly GITHAKA Arata HIDANO Kyle TAYLOR Takuya ITO Ai TAKANO Shuji ANDO Hiroki KAWABATA Toshio TSUBOTA Shiro MURATA Kazuhiko OHASHI
出版者
公益社団法人 日本獣医学会
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
vol.75, no.2, pp.215-218, 2013 (Released:2013-03-01)
参考文献数
27
被引用文献数
8 17

In this study, the prevalence of Borrelia infections in Ixodes ticks from a site in Hokkaido, Japan, with confirmed cases of Lyme disease was determined by a PCR method capable of detecting and differentiating between strains of pathogenic Borrelia, with particular emphasis on Borrelia garinii (B. garinii) and Borrelia afzelli (B. afzelli), using tick-derived DNA extracts as template. A total of 338 ticks, inclusive of 284 Ixodes persulcatus (I. persulcatus), were collected by flagging vegetation in mid-spring. Ninety-eight (34.5%) of I. persulcatus tested positive for Borrelia species DNA, whereas the overall prevalence of Borrelia species in Ixodes ovatus and Haemaphysalis longicornis ticks was 19.5 and 7.7%, respectively. PCR-RFLP and sequence analysis of Borrelia rrf(5S)-rrl(23S) intergenic spacer DNA amplicons indicated that they originated from three different Borrelia species namely, B. garinii, B. afzelii and B. japonica. Among the I. persulcatus species, which is a known vector of human borreliosis, 86 were mono-infected with B. garinii, 2 ticks were mono-infected with B. afzelii and whereas 12 ticks had dual infections. Most significant, 11 of the I. persulcatus ticks were coinfected with Anaplasma phagocytophilum and B. garinii. The difference between the number of obtained and expected co-infections was significant (χ2=4.32, P=0.038).
著者
Hun-Young YOON Dong-Wook SHIN Keum Soon IM Soon-Wuk JEONG
出版者
公益社団法人 日本獣医学会
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
vol.75, no.2, pp.237-240, 2013 (Released:2013-03-01)
参考文献数
10

We report here the clinical presentation and successful surgical management of synovial hemangioma accompanied by cruciate ligament injury in a dog. Surgical correction of cruciate ligament injury was performed after removing torn cruciate ligaments, synovial mass and masses attached to the ligaments and distal femoral articular cartilage. At 10 months, the dog has showed no evidence of recurrence in the stifle joint. Synovial hemangioma, although a seemingly rare cause of stifle joint pathology, should be considered in the differential diagnosis for cruciate ligament injury when a circumscribed intra-articular soft tissue mass is evident radiographically with cranial or caudal drawer motion. This is the first case report in a dog to describe synovial hemangioma accompanied by cruciate ligament injury.
著者
Sawane MITANI Akira YABUKI Kazuyuki TANIGUCHI Osamu YAMATO
出版者
公益社団法人 日本獣医学会
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
vol.75, no.2, pp.127-133, 2013 (Released:2013-03-01)
参考文献数
30
被引用文献数
9 26

The association of renin and angiotensin II, which are potent components of the renin–angiotensin system, with the severity of chronic renal disease was investigated immunohistochemically in dogs and cats. Immunoreactivities of renin and angiotensin II were evaluated quantitatively, and their correlations with the degrees of glomerulosclerosis, glomerular hypertrophy, interstitial cell infiltration and interstitial fibrosis were statistically analyzed. Immunoreactivities for renin were detected in afferent arteries in both dogs and cats. The score of renin-positive signals showed no correlation with plasma creatinine concentration or any of the histopathological parameters, except for the diameter of glomeruli in dogs. Immunoreactivities for angiotensin II were detected in tubules (primarily proximal tubules) and interstitial mononuclear cells in both dogs and cats. The score of tubular angiotensin II correlated with glomerulosclerosis and cell infiltration in cats but not in dogs. The score of interstitial angiotensin II correlated with plasma creatinine concentration, glomerulosclerosis, cell infiltration and fibrosis in dogs and with glomerulosclerosis and cell infiltration in cats. In conclusion, the results of the study suggest that intrarenal renin-angiotensin system is correlated with the severity of kidney disease, with the underlying mechanism differing between dogs and cats.
著者
Shingo MAEDA Yasuhito FUJINO Chie TAMAMOTO Satoshi SUZUKI Atsushi FUJITA Masashi TAKAHASHI Koichi OHNO Kazuyuki UCHIDA Hajime TSUJIMOTO
出版者
公益社団法人 日本獣医学会
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
vol.75, no.2, pp.187-190, 2013 (Released:2013-03-01)
参考文献数
23
被引用文献数
1 5

A 13-year-old, neutered male miniature dachshund was presented with a one-month history of bilateral symmetrical swelling in the pinnae and carpal, cubital and tarsal joints, and swelling in the tail. The lesions were histopathologically characterized by multiple dilated lymphatic vessels lined by a single attenuated layer of endothelial cells. The subcutis was predominantly involved. A number of spindle-shaped cells lining the irregular vessels were observed. Morphological atypia was not evident in these cells. Immunohistochemical analyses revealed that the proliferating endothelial cells were positive for factor VIII-related antigen and CD31. Based on the clinical presentation and histopathological features, the dog was diagnosed with lymphangiomatosis. Treatment with anti-inflammatory prednisolone improved the symptoms.
著者
Takuma AOKI Keisuke SUGIMOTO Hiroshi SUNAHARA Yoko FUJII
出版者
公益社団法人 日本獣医学会
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
vol.75, no.2, pp.199-202, 2013 (Released:2013-03-01)
参考文献数
17
被引用文献数
8 14

We report two feline cases of patent ductus arteriosus (PDA) with pulmonary hypertension (PH). The subjects were both intact domestic shorthair cats, a 4-month-old, 2.5 kg male (case 1) and an 8-month-old, 2.12 kg female (case 2). At the first presentation, left-sided congestive heart failure was diagnosed in case 1 and severe aortic stenosis (AS) in case 2. Following surgical ligation of the ductus arteriosus (DA), furosemide therapy was no longer required in case 1, and the severe AS improved to mild status in case 2 perhaps because of reduced volume overload. In case 2, severe hypoxemia was revealed after surgery; however, this normalized within 96 days after surgery.
著者
Kana MIMURA Akihiro MORI Peter LEE Kaori UEDA Hitomi ODA Kaori SAEKI Toshiro ARAI Toshiro SAKO
出版者
公益社団法人 日本獣医学会
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
pp.12-0310, (Released:2013-03-01)
被引用文献数
1 5

Diet therapy is an important treatment component available for obese cats. In this study, the impact of four commercially available prescription diet regimens [1 for general use and 3 aimed at treating obesity and diabetes mellitus (DM)] on short-term post-prandial serum glucose, insulin, triglyceride and non-esterified fatty acid (NEFA) concentrations was investigated with five obese cats. The diet regimens used were as follows: C/D dry (general use: moderate protein, moderate fat, high carbohydrate and low fiber); M/D dry (DM: high protein, high fat, low carbohydrate and high fiber); W/D dry (DM: high protein, low fat, high carbohydrate and high fiber); and Diabetic dry (DM: high protein, low fat, low carbohydrate and high fiber). A significant reduction (10–13%) in postprandial glucose (area under the curve; AUC) was observed with the M/D and Diabetic diets, which both contained lower concentrations of carbohydrates than the C/D diet. An accompanying significant reduction (30–36%) in postprandial insulin AUC was also observed with the three DM diets, which all had higher amounts of fiber, as compared with the C/D diet. Lastly, a significant increase (32–65%) in postprandial NEFA AUC was observed with the M/D and Diabetic diets as compared with the C/D diet. Therefore, dietary amounts of carbohydrates and fiber, as opposed to protein content or dietary fat, appear to have a very significant impact on post-prandial glycemia and subsequent insulin requirement levels in obese cats. In addition, dietary amounts of carbohydrate may also impact lipid metabolism in obese cats.
著者
Hiroki OKANISHI Jun MATSUMOTO Sadao NOGAMI Yumiko KAGAWA Toshihiro WATARI
出版者
公益社団法人 日本獣医学会
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
pp.12-0518, (Released:2013-03-01)
被引用文献数
1

An 8-year-old male Shiba dog presented with chronic vomiting and diarrhoea. Upper gastrointestinal endoscopy revealed severe enteritis and infection of the duodenal mucosa with Echinostoma hortense. We performed therapy for parasites and enteritis. The therapy was successful for deworming, and temporarily improved the symptoms, but the dog died soon thereafter. To the authors’ knowledge, this is the first case report of an ante mortem diagnosis of E. hortense infection in a dog.
著者
MASATOMI KUDAKA HITOSHI FUKASE RYOSUKE KIMURA TSUNEHIKO HANIHARA HIROFUMI MATSUMURA AIKO SASO TADAHIKO FUKUMINE HAJIME ISHIDA
出版者
日本人類学会
雑誌
Anthropological Science (ISSN:09187960)
巻号頁・発行日
pp.121125, (Released:2013-02-19)
被引用文献数
6 13

Twelve metric variables of the humerus, radius, femur, and tibia were investigated in 11 male samples from northeastern and eastern Asian populations. Variations among regions and correlations between latitude and respective measurements and indices were calculated and a principal component analysis was conducted to elucidate human limb bone characteristics. Significant correlation and marginally significant correlation were found for the maximum subtrochanteric diameter (r = 0.662, P = 0.027) and the platymeric index (r = -0.583, P = 0.060) with latitude, respectively, suggesting that the femur of northern Asians had a wide and flat subtrochanteric shape. The second principal component of the principal component analysis shows that the northeastern samples with comparatively long shaft length and thin and flat shaft diameters were discriminated from the southern samples; the second principal component was significantly correlated with latitude (r = -0.743, P = 0.009). The estimated Fst value of 0.432–0.336 shows that the variation in limb bone measurements across regions is rather large, at approximately two or three times the low levels of interregional variation (0.078–0.180) in analyses of cranial and dental data. Limb bone morphology has been repeatedly proposed to be more strongly influenced by environmental and nutritional factors than cranial and dental traits, but this study is the first to confirm it on the basis of statistical analysis.
著者
Sachiko Tomioka Toshiro Aigaki Takashi Matsuo
出版者
日本遺伝学会
雑誌
Genes & Genetic Systems (ISSN:13417568)
巻号頁・発行日
vol.87, no.5, pp.323-329, 2012 (Released:2013-02-13)
参考文献数
13
被引用文献数
2 7

Insect odorant-binding proteins function in the sensing of odors, tastes, and pheromones. Genes encoding two odorant-binding proteins, Obp57d and Obp57e, were identified to be involved in the behavioral adaptation of Drosophila sechellia to its host plant. The two genes are expressed in cells associated with taste sensilla on the legs, and the expression pattern in the legs is conserved among closely related species. To identify the cis-regulatory elements necessary for the expression in the leg sensilla, the promoter sequences of Obp57d and Obp57e were compared among species. Two types of conserved sequence-motifs were found as candidate cis-regulatory elements. Functions of these conserved elements in the promoters of D. melanogaster Obp57d and Obp57e were examined by using a newly constructed vector that combines the advantages of φC31 integrase-based transformation and gypsy transposable-element-derived insulators. By GFP-reporter assay using the new vector, it was confirmed that these conserved elements are necessary for the expression in the legs, working synergistically with each other to affect the expression level. Single-nucleotide substitutions in these elements dramatically changed the promoter activity. These results provide insight into the molecular mechanism for evolution of adaptive behavior via modulation of OBP expression levels.
著者
叶内 敦子
出版者
日本第四紀学会
雑誌
第四紀研究 (ISSN:04182642)
巻号頁・発行日
vol.27, no.3, pp.177-186, 1988 (Released:2009-08-21)
参考文献数
16
被引用文献数
7 12

This paper describes the palynological study of a core from Yanohara Bog, Fukushima Prefecture, northeastern Japan. Four marker tephras laid down during the Last Glacial Period are recognized in the core: Pm-1, Aso-4, DKP, and AT.The pollen diagram obtained is divided into five pollen zones. The ages of the boundaries between the pollen zones are calculated from the depositional rate of the marker tephra. YH-I (about 8-5.7m.y.B.P.) corresponds to the early Last Glacial Age. Both YH-IIa (about 5.7-5.0m.y.B.P.) and YH-IV(2.6-1.4m.y.B.P.) correspond to cold stages. YH-V corresponds the Holocene.It is clear that there were two cold stages and one relatively warm stage during the Last Glacial Period. From pollen analytical data, it is found that the earlier cold stage(YH-IIa) was colder to than the later stage(YH-IV).
著者
谷 茂 長谷川 高士
出版者
社団法人 農業農村工学会
雑誌
農業土木学会誌 (ISSN:03695123)
巻号頁・発行日
vol.55, no.10, pp.939-947,a1, 1987-10-01 (Released:2011-08-11)
参考文献数
18

地震によつて多くの溜池に被害が発生してきた。本報文では記録が残っている過去五つの地震での溜池被害を文献・資料・現地調査等により調査した。とくに日本海中部地震については, 無被害溜池も含めた堤体土の試料採取を行い土質試験を行つた。これらの調査・実験から, 溜池の被害形態の分類を行い, その特徴を述べた。また被害の主な原因が液状化の可能性が強いことを, 土質試験等のデータからも裏づけた。
著者
片瀬 隆雄 和田 英太郎
出版者
公益社団法人 日本分析化学会
雑誌
分析化学 (ISSN:05251931)
巻号頁・発行日
vol.39, no.8, pp.451-456, 1990-08-05 (Released:2010-01-18)
参考文献数
16
被引用文献数
7 10

炭素及び窒素安定同位体比測定の試料を得る目的で,クロロフィルaをアオコ(Microcystis spp.)から1~10mgオーダーで単離する方法を検討した.凍結試料を無水硫酸ナトリウムと共に乳鉢中で混合し,アセトンで抽出後,同液からジオキサンで粗性クロロフィルを沈殿させ,更にジエチルアミノエチル-トヨパール陰イオン交換樹脂及びセファロース・ゲル濾過担体カラムでクロロフィルaを単離する方法を検討した.この方法で,実際に諏訪湖から経時的に採取したアオコの4試料からクロロフィルaを2.3~3.8mg単離し,未処理の乾燥アオコ及び単離の過程で得られた分画物を合わせて18試料の炭素同位体比(13C/12C)及び窒素同体比(15N/14N)を測定した.その結果,アオコ単離のクロロフィルaの炭素・窒素同位体比が経時的に変化していることが明らかとなった.
著者
Yoshimi NIWANO Takashi ADACHI Jun KASHIMURA Takashi SAKATA Hajime SASAKI Kazunori SEKINE Satoshi YAMAMOTO Akie YONEKUBO Shuichi KIMURA
出版者
Center for Academic Publications Japan
雑誌
Journal of Nutritional Science and Vitaminology (ISSN:03014800)
巻号頁・発行日
vol.55, no.3, pp.201-207, 2009 (Released:2009-07-15)
参考文献数
41
被引用文献数
18 46

This review assesses the feasibility of using glycemic index (GI) as a predictor of appetite, hunger and satiety by surveying published human intervention studies. We also discuss the relationship between GI and two appetite/satiety control hormones, leptin and ghrelin. Ingestion of high-GI food increased hunger and lowered satiety in short-term human intervention studies. This effect may be attributed to the rapid decline in blood glucose level following a hyperinsulinemic response caused by a sharp and transient increase in blood glucose level that occurs after the ingestion of high-GI food, which is defined as the glucostatic theory. However, appetite, hunger and satiety after the ingestion of foods with varying GI were inconsistent among long-term human intervention studies. From the few relevant long-term studies available, we selected two recent well-designed examples for analysis, but they failed to elicit clear differences in glycemic and insulinemic responses between high- and low-GI meals (consisting of a combination of different foods or key carbohydrate-rich foods incorporated into habitual diets). One of the reasons that these studies could not predict glycemic response to mixed meals is presumably that the GI of each particular food was not reflected in that of the mixed meals as a whole. Thus, it is difficult to conclude that the GI values of foods or mixed meals are a valid long-term predictor for appetite, hunger and satiety. Both insulin and insulin-mediated glucose uptake and metabolism in adipose tissue affect blood leptin concentration and its diurnal pattern. Circulating ghrelin level is suppressed by carbohydrate-rich meals, presumably via glycemia and insulinemia. Accordingly, low-GI foods may not necessarily increase satiety or suppress appetite and/or hunger because of the lack of insulin-mediated leptin stimulation and ghrelin suppression. However, insulin-mediated leptin stimulation and ghrelin suppression per se is not consistent among studies; thus we were not able to identify a clear relationship among GI, satietogenic leptin, and appetitic ghrelin.