著者

Yuval RAMOT Michal STEINER Netanel AMOUYAL Yossi LAVIE Guy KLAIMAN Abraham J. DOMB Abraham NYSKA Tal HAGIGIT

出版者

JAPANESE SOCIETY OF TOXICOLOGIC PATHOLOGY

雑誌

Journal of Toxicologic Pathology (ISSN:09149198)

巻号頁・発行日

pp.2020-0041, (Released:2020-08-31)

被引用文献数

3

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Fracture-related infections remain a leading cause of morbidity and mortality. We aimed to establish a simple contaminated radial osteotomy model to assess the efficacy of a biodegradable polymer poly(sebacic-co-ricinoleic acid) [p(SA-RA)] containing 20% w/w gentamicin. A unilateral transverse osteotomy was induced in Sprague-Dawley (SD) rats, followed by application of Staphylococcus aureus suspension over the fracture. After successfully establishing the contaminated open fracture model, we treated the rats either systemically (intraperitoneal cefuroxime), locally with p(SA-RA) containing gentamicin, or both. Control groups included non-contaminated group and contaminated groups that were either untreated or treated with the polymer alone. After 4 weeks, the bones were subjected to micro-CT scanning and microbiological and histopathology evaluations. Micro-CT analysis revealed similar changes in the group subjected to both local and systemic treatment as in the non-contaminated control group. Lack of detectable bacterial growth was noted in most animals of the group subjected to both local and systemic treatment, and all samples were negative for S. aureus. Histopathological evaluation revealed that all treatment modalities containing antibiotics were highly effective in reducing infection and promoting callus repair, resulting in early bone healing. While p(SA-RA) containing gentamicin treatment showed better results than cefuroxime, the combination of local and systemic treatment displayed the highest therapeutic potential in this model.

著者

片山 信夫 高野 幸雄 加藤 一郎 加藤 敏郎 中川 進

出版者

一般社団法人 日本鉱物科学会

雑誌

鉱物学雜誌 (ISSN:04541146)

巻号頁・発行日

vol.2, no.1, pp.46-52, 1954-09-30 (Released:2009-08-11)

参考文献数

12

著者

Susanna JÄRVELIN-PASANEN Sanna SINIKALLIO Mika P. TARVAINEN

出版者

National Institute of Occupational Safety and Health

雑誌

Industrial Health (ISSN:00198366)

巻号頁・発行日

vol.56, no.6, pp.500-511, 2018 (Released:2018-11-21)

参考文献数

63

被引用文献数

11 130

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The aim of this systematic review was to explore studies regarding association between occupational stress and heart rate variability (HRV) during work. We searched PubMed, Web of Science, Scopus, Cinahl and PsycINFO for peer-reviewed articles published in English between January 2005 and September 2017. A total of 10 articles met the inclusion criteria. The included articles were analyzed in terms of study design, study population, assessment of occupational stress and HRV, and the study limitations. Among the studies there were cross-sectional (n=9) studies and one longitudinal study design. Sample size varied from 19 to 653 participants and both females and males were included. The most common assessment methods of occupational stress were the Job Content Questionnaire (JCQ) and the Effort-Reward Imbalance (ERI) questionnaire. HRV was assessed using 24 h or longer Holter ECG or HR monitoring and analyzed mostly using standard time-domain and frequency-domain parameters. The main finding was that heightened occupational stress was found associated with lowered HRV, specifically with reduced parasympathetic activation. Reduced parasympathetic activation was seen as decreases in RMSSD and HF power, and increase in LF/HF ratio. The assessment and analysis methods of occupational stress and HRV were diverse.

著者

Kakui Keiichi Hiruta Chizue Uyeno Daisuke

出版者

Wiley

雑誌

Invertebrate Biology (ISSN:10778306)

巻号頁・発行日

vol.138, no.3, pp.e12257, 2019-09

被引用文献数

3

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With more than 40,000 species, Malacostraca is the most diverse crustacean class. Most malacostracans are gonochoristic, but simultaneous hermaphrodites are also known. Tanaidacea is one of two malacostracan orders that includes simultaneously hermaphroditic species; so far, simultaneous hermaphroditism has been confirmed externally and internally in only two tanaidacean species, both in the genus Apseudes (Apseudidae). Here we show, through external and internal morphological observations of fixed specimens, that the apseudid Falsapseudes bowmani is a simultaneous hermaphrodite, making Falsapseudes the second tanaidacean genus in which simultaneous hermaphroditism has been confirmed both externally and internally. In this species, the epistome (a projection on the clypeus) was thick and elongate in large specimens but was thin and spiniform in smaller specimens; the brooding of eggs or embryos was observed only in thin-epistome individuals, although a pair of ovaries was confirmed in both thick- and thin-epistome individuals. This suggests that individuals with a thick epistome may act as males while also retaining the female reproductive organs.

著者

小林 大輔 清水 博之 杉崎 正志 重松 司朗

出版者

一般社団法人 日本顎関節学会

雑誌

日本顎関節学会雑誌 (ISSN:09153004)

巻号頁・発行日

vol.28, no.3, pp.232-239, 2016-12-20 (Released:2017-02-13)

参考文献数

23

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顎関節症発症に関与する因子は多因子性であり睡眠障害もその一因とされているが,その因果関係についての研究は少なく十分に解明されていない点も多い。顎関節症患者,特に咀嚼筋痛障害を有する患者に対し睡眠障害との関連性について質問票を用いて検討を行った。対象は,2015年4月1日より2016年3月31日までに当科を受診した,咀嚼筋痛障害を有する顎関節症女性患者40名とし,顎関節症症状のない女性30名を対照群とした。睡眠障害に関してはピッツバーグ睡眠質問票日本語版(以下PSQI-J)を用いて評価した。患者群に対する調査項目は咬筋部圧痛,開口時咬筋部痛,無痛自力最大開口量,日常生活支障度とした。2群を比較した結果,PSQI-Jスコアは有意に患者群のほうが高かった。またPSQI-Jの各項目と各症状との関連を調べた結果では,<睡眠の質>では咬筋部圧痛(p=0.036),<入眠時間>では咬筋部圧痛(p=0.009),<睡眠時間>では日常生活支障度(p=0.021),<眠剤の使用>では開口時咬筋部痛(p=0.026),および咬筋部圧痛(p=0.024)が有意な関連を認めた。また患者群におけるPSQI-J合計スコアと咬筋部圧痛に有意な関連を認めた(p=0.003)。睡眠障害が顎関節症,特に咀嚼筋痛障害の発症に関連をもつことが改めて示唆された。

著者

村上 一博

出版者

明治大学史資料センター

雑誌

大学史紀要 (ISSN:13498231)

巻号頁・発行日

no.25, pp.76-93, 2019-03-30

著者

小澤 知広

出版者

一般社団法人 電気設備学会

雑誌

電気設備学会誌 (ISSN:09100350)

巻号頁・発行日

vol.25, no.10, pp.781-783, 2005-10-10 (Released:2015-06-26)

参考文献数

2

著者

杉村広太郎 著

出版者

朝日新聞社

巻号頁・発行日

1929

著者

森原 徹 平本 真知子 木田 圭重

出版者

日本臨床スポーツ医学会

雑誌

日本臨床スポーツ医学会誌 (ISSN:13464159)

巻号頁・発行日

vol.23, no.1, pp.20-24, 2015

著者

池邉 一典

出版者

一般社団法人 日本老年歯科医学会

雑誌

老年歯科医学 (ISSN:09143866)

巻号頁・発行日

vol.35, no.1, pp.19-28, 2020-06-30 (Released:2020-07-23)

参考文献数

24

著者

前田 陽

出版者

小樽商科大学

雑誌

商学討究 (ISSN:04748638)

巻号頁・発行日

vol.59, no.1, pp.187-206, 2008-07-25

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論説

著者

Takatoshi Kitazawa Yasuo Ota Nanae Kada Yuji Morisawa Atsushi Yoshida Kazuhiko Koike Satoshi Kimura

出版者

The Japanese Society of Internal Medicine

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

vol.45, no.5, pp.317-321, 2006 (Released:2006-04-03)

参考文献数

22

被引用文献数

9 13

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Vancomycin, an antibiotic to which methicillinresistant Staphylococcus aureus (MRSA) is sensitive, frequently induces hypersensitivity reactions. Lowering the vancomycin infusion rate and/or premedicating with antihistamine effectively reduce hypersensitivity in most cases. However, vancomycin desensitization is sometimes the only way to ensure safe use. Two types of desensitization protocols have been reported, and these utilize different infusion intervals; rapid desensitization and slow desensitization. We herein report a case of vancomycin hypersensitivity with methicillinresistant Staphylococcus aureus infection. A combination of the two desensitization protocols, rapid desensitization followed by slow desensitization, effectively inhibited the hypersensitivity reaction during vancomycin infusion, and methicillinresistant Staphylococcus aureus was successfully eradicated.

著者

重松 英朗 中村 吉昭 古閑 知奈美 森 恵美子 大野 真司

出版者

日本臨床外科学会

雑誌

日本臨床外科学会雑誌 (ISSN:13452843)

巻号頁・発行日

vol.69, no.12, pp.3069-3073, 2008 (Released:2009-06-11)

参考文献数

10

被引用文献数

8 8

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Corynebacterium kroppenstedtii感染により発症し乳癌との鑑別を要したgranulomatous mastitisの1例を経験したので報告する.症例は47歳,女性.1カ月前より右乳房腫瘤を自覚し当科受診.右乳房A領域に3cm大の腫瘤を認めた.理学的所見,画像所見より右乳癌が疑われたが針生検組織診で確定診断が得られなかったため外科的生検術を行った.病理組織所見では肉芽腫の形成と多核巨細胞を含む炎症細胞浸潤を認め悪性所見は認められなかった.細菌培養にてCorynebacterium kroppenstedtiiを認め,Corynebacterium kroppenstedtii感染により発症したgranulomatous mastitisと診断した.治療として排膿ドレナージ後,塩酸ミノサイクリン内服治療を3週間施行し治癒を認めた.Granulomatous mastitisの診療においてCorynebacterium kroppenstedtii感染の可能性を考慮することが必要と考えられた.

著者

岩坂 憂児 大友 伸太郎

出版者

一般社団法人 Asian Society of Human Services

雑誌

Total Rehabilitation Research (ISSN:21881855)

巻号頁・発行日

vol.8, pp.22-28, 2020 (Released:2020-06-30)

参考文献数

10

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The purpose of this study was to investigate and compare the one-day stress load between the users and providers of day service. The subjects were 2 users (a man in his 50s with right hemiplegia and a man in his 70s with Parkinson's disease syndrome) and 2 providers (a physical therapist and manager, a man in his 40s and a nurse, a woman in her 40s). A salivary amylase monitor was used for measurement, which objectively measures stress based on the activity value of salivary amylase. The subjects underwent measurements of salivary amylase activity at the time of arrival at the facility (baseline) and continued to undergo measurements every 15 minutes thereafter until they returned home. In addition, there was a meal break from 12:00 to 14:00, leading to a possibility that the secretion in saliva was changed by the meal had; thus, it was excluded from the measured value. In order to confirm the stress load of users and providers, Welch’s t-test was performed with the user and target as independent variables and the values obtained by dividing each measured value by the baseline value as the dependent variables. The significance level was 5%. There was a significant difference in the salivary amylase activity between users of day service and providers (p <0.05). This study revealed that providers’ stress is higher than users’ stress, and providers’ stress increased with team meetings and patient transfers. This study suggests the importance of stress management for providers.

著者

清水 悠夏

出版者

愛知教育大学数学教育講座

雑誌

イプシロン (ISSN:0289145X)

巻号頁・発行日

vol.58, pp.143-146, 2016-03-24

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平成27年度 修士論文 抄録

著者

石井 文子 安齋 有紀子 伊藤 玲香 小山 直人 北川 忠生

出版者

一般社団法人 日本魚類学会

雑誌

魚類学雑誌 (ISSN:00215090)

巻号頁・発行日

vol.58, no.1, pp.65-74, 2011 (Released:2014-03-07)

参考文献数

19

被引用文献数

1

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The Yoshino diversion (Yoshino Bunsui) was established to supply irrigation water from the Yoshino River to the Yamato plain. In order to examine fish introductions through the canals of the Yoshino Bunsui, the genetic structure of 17 populations of dark chub Zacco temminckii collected from the Yamato and Yoshino rivers were analyzed and their mtDNA ND2 sequences studied. A total of 16 haplotypes were detected in 261 individuals, 6 haplotypes being present in both rivers. In the Yamato River, the shared haplotypes were found to be associated with the locations of inflows from the Yoshino Bunsui. On the other hand, the majority of haplotypes found in individuals from the Yamato River were not found in those from the Yoshino River. This study confirmed the secondary introduction of dark chub from the Yoshino River into the Yamato River via the Yoshino Bunsui.

著者

モングーシュ マリーナ V. Marina V. Mongush

出版者

国立民族学博物館

雑誌

国立民族学博物館研究報告 = Bulletin of the National Museum of Ethnology (ISSN:0385180X)

巻号頁・発行日

vol.38, no.1, pp.35-62, 2013-12-25

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This article is a preliminary report on the international expedition to theTuvans in China, Russia, and Mongolia that was conducted in the summer of2012 as a Cultural Resource Project of the National Museum of Ethnology(Minpaku). The author investigates features of the way of life and cultureof the Tuvans living in these countries and clarifies the similarities anddifferences arising from their different social circumstances. The majorityof Tuvans live in Russia, where they have a recognized position and territory—the Tuva Republic. In the territories of China and Mongolia, Tuvansare national minorities and do not have national-territorial status. HoweverTuvans of all three countries still keep their native language, ethnic consciousnessand traditional culture. This article focuses on elements rangingfrom “historical baggage” to the language and cultural situation of this community,to relations with the host societies, and to the interaction betweenthese factors.

著者

畑本 裕介 Yusuke Hatamoto

出版者

同志社大学政策学会

雑誌

同志社政策科学研究 = Doshisha University policy & management review (ISSN:18808336)

巻号頁・発行日

vol.21, no.2, pp.1-14, 2020-03-01

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社会福祉行政研究に関係するミクロ権力論には、社会学権力論と行政学的権力論の二つの流れがある。この論文では、行政学的権力論を切り開いたリプスキーのストリート・レベルの官僚制(SLB)論を大きく取り上げ、社会福祉行政研究におけるその適用可能性について検討している。また、SLBの在り方が現代において変化した要因についても考察している。それは行政への批判的態度の増大、ガバナンス改革、福祉専門職の行政への進出といったものである。

著者

浜村裕 (無咎) 著

出版者

溝口与三郎

巻号頁・発行日

vol.初集 3, 1899

著者

黒田 重雄

出版者

北海道大学經濟學部

雑誌

北海道大學 經濟學研究 (ISSN:04516265)

巻号頁・発行日

vol.30, no.1, pp.25-63, 1980-03