著者
藤原 了 橋本 紀彦 是永 眞理子 田宮 貴洋
出版者
一般社団法人 日本原子力学会
雑誌
日本原子力学会和文論文誌 (ISSN:13472879)
巻号頁・発行日
pp.J14.025, (Released:2015-12-17)
参考文献数
32
被引用文献数
1 1

Since the 2011 Tohoku-Oki Earthquake, evaluations based on a tsunami simulation approach have had a very important role in promoting tsunami disaster prevention measures in the case of mega-thrust earthquakes. When considering tsunami disaster prevention measures based on the knowledge obtained from tsunami simulations, it is important to carefully examine the type of tsunami source model. In current tsunami simulations, there are various ways to set the tsunami source model, and a considerable difference in tsunami behavior can be expected among the tsunami source models. In this study, we carry out a tsunami simulation of the 2011 Tohoku-Oki Earthquake around Fukushima Daiichi (I) Nuclear Power Plant and Fukushima Daini (II) Nuclear Power Plant in Fukushima Prefecture, Japan, using several tsunami source models, and evaluate the difference in the tsunami behavior in the tsunami inundation process. The results show that for an incoming tsunami inundating an inland region, there are considerable relative differences in the maximum tsunami height and wave pressure. This suggests that there could be false information used in promoting tsunami disaster prevention measures in the case of mega-thrust earthquakes, depending on the tsunami source model.
著者
喜入 暁 越智 啓太
出版者
日本認知心理学会
雑誌
日本認知心理学会発表論文集 日本認知心理学会第11回大会
巻号頁・発行日
pp.155, 2013 (Released:2013-11-05)

女性の魅力評価における研究で,Dixson et al. (2011)は,WHR2パタン×バストサイズ3パタンの刺激を用いた実験を行い,バストサイズに関係なく低WHRが魅力的であると判断されるにもかかわらず,視線は顔やバストにのみ大きく注意が向けられることを示した。しかしこれに関して刺激による影響が考えられる。完全に全裸の実験刺激を用いたので,普段見ることのない新奇な身体的特徴をよりよく注視したという可能性である。本研究では水着を着用した女性で,WHRのみを編集した5パタンの刺激を用いて実験を行った。この結果,視線に関してDixson et al. (2011)のような結果は示されず,身体のそれぞれの領域に同程度の注意が向けられることが示された。
著者
Kenzo Tanaka Koichiro Gibo Hiroko Watase Masaki Oohashi Carlos A. Camargo Kohei Hasegawa on behalf of the Japanese Emergency Medicine Network Investigators
出版者
日本プライマリ・ケア連合学会
雑誌
Journal of General and Family Medicine (ISSN:21896577)
巻号頁・発行日
vol.16, no.4, pp.281-287, 2015-12-20 (Released:2015-12-25)
参考文献数
14

Background: Little is known about the extent that acute asthma is inappropriately treated with antibiotics in Japanese emergency departments (EDs).Objectives: We examined the proportion and predictors of inappropriate antibiotic use for adults with acute asthma in the Japanese EDs.Methods: We conducted a chart review study in 23 Japanese EDs. Subjects were ED patients aged 18 to 54 years with acute asthma between 2009 and 2011. To examine predictors of inappropriate antibiotic use, we performed multi-level logistic regression analysis at both the patient- and ED-level modeling EDs as a random variable.Results: Among 1380 patients in the overall study, the analytic cohort comprised 1311 patients. Overall, antibiotics were inappropriately prescribed for 4.4% (95% confidence interval [CI], 3.4%–5.7%). In the multi-level logistic regression analysis, higher annual ED asthma visit volume was significantly associated with a lower proportion of inappropriate antibiotic use (odds ratio per 100-visit increase, 0.3 ; 95%CI, 0.2–0.6).Conclusions: In this large multicenter study in Japan, we found that approximately 4% of ED patients with acute asthma were inappropriately treated with antibiotics. We also demonstrated that the inappropriate use of antibiotics largely differed across the EDs and was less common in EDs with a more annual ED asthma visits. Organized knowledge translation initiatives are warranted to address this gap in emergency asthma care.
著者
髙本 真寛 高田 治樹
出版者
公益社団法人 日本心理学会
雑誌
心理学研究 (ISSN:00215236)
巻号頁・発行日
pp.86.14336, (Released:2015-11-10)
参考文献数
34
被引用文献数
2

This study used structural equation modeling to investigate directional relationships between coping with interpersonal stress and received support. One hundred and seventy-seven undergraduates who had experienced interpersonal stress during the past month answered questions about coping with interpersonal stress and received support. Structural equation modeling based on third-order moment structures was used to examine the directionality of the relationship between these two variables. The results revealed interactive associations between distancing and emotional support. Received support affected coping with interpersonal stress in terms of active coping, planning and monitoring, and positive reappraisal. These results suggest that received support functions as a coping resource.
著者
山中 隆嗣 渡辺 愛子 中塚 伸一 庄田 裕紀子
出版者
日本皮膚科学会大阪地方会・日本皮膚科学会京滋地方会
雑誌
皮膚の科学 (ISSN:13471813)
巻号頁・発行日
vol.9, no.1, pp.82-86, 2010-02-28 (Released:2011-04-26)
参考文献数
17
被引用文献数
1

58歳,男性。17年ほど前より右大腿部に移動性の皮下腫瘤を自覚し,夏には鶏卵大まで増大し,冬には縮小していた。その特異な症状より寄生虫感染を疑った。摘出前に超音波検査を施行し,摘出時には生きた虫体を観察することができた。病理組織学的には,脂肪組織内に好酸性の外被に覆われた粗な内部構造を有する虫体と,軽度の好酸球浸潤を伴う肉芽腫反応を認める結節が確認され,ELISA 法の結果から,17年という比較的長期間寄生したマンソン孤虫症と診断した。
著者
時田 澄男
出版者
日本コンピュータ化学会
雑誌
Journal of Computer Chemistry, Japan (ISSN:13471767)
巻号頁・発行日
vol.14, no.5, pp.A38-A41, 2015 (Released:2015-12-18)
参考文献数
9
被引用文献数
1 1

水素原子の波動方程式を解くと,無数の原子軌道が導出される.これらのうち,z軸方向に伸びる p, d, および,f軌道をガラスブロック内に実3次元で彫刻し,球殻状節面や円錐面節面の描かれ方を調べた.
著者
Noriyuki MORI Saki NAKANISHI Seiko SHIOMI Shoko KIYOKAWA Sachie KAKIMOTO Kaku NAKAGAWA Kazunori HOSOE Kazuhiro MINAMI Tomonori NADAMOTO
出版者
Center for Academic Publications Japan
雑誌
Journal of Nutritional Science and Vitaminology (ISSN:03014800)
巻号頁・発行日
vol.61, no.5, pp.406-416, 2015 (Released:2015-12-04)
参考文献数
16
被引用文献数
1 5

Licorice flavonoid oil (LFO) is a new functional food ingredient consisting of hydrophobic licorice polyphenols in medium-chain triglycerides. Recent studies reported that LFO prevented and ameliorated diet-induced obesity via the regulation of lipid metabolism-related gene expression in the livers of mice and rats, while it reduced body weight in overweight human subjects by reducing total body fat. However, the direct effects of LFO on energy metabolism have not been studied in human subjects. Therefore, we investigated the effects of ingestion of LFO on energy metabolism, including fat oxidation, by measuring body surface temperature under resting conditions and respiratory gas analysis under exercise conditions in healthy humans. We showed that ingestion of a single 600 mg dose of LFO elevated body trunk skin temperature when measured in a slightly cooled air-conditioned room, and increased oxygen consumption and decreased the respiratory exchange ratio as measured by respiratory gas analysis during 40% Vo2max exercise with a cycle ergometer. Furthermore, repeated ingestion of 300 mg of LFO for 8 d decreased respiratory exchange during the recovery period following 40 min of 30% Vo2max exercise on a treadmill. These results suggest that LFO enhances fat oxidation in humans during light exercise.
著者
服部 慈久 岡本 有紀子 中村 康夫 紙本 薫 鈴村 宏
出版者
一般社団法人日本医薬品情報学会
雑誌
医薬品情報学 (ISSN:13451464)
巻号頁・発行日
vol.17, no.3, pp.164-168, 2015 (Released:2015-12-18)
参考文献数
5

Objective: When vehicular accidents occur as a result of impaired consciousness etc., because of adverse drug reactions, there is a risk that third parties may be harmed.  Till date, at Nagoya City East Medical Center (hereinafter, our hospital), the warnings about driving motor vehicles while taking drugs has varied depending on the doctor or pharmacist who provides the guidance.  Therefore, throughout our hospital, we aimed to standardize these warnings and to introduce measures to strictly enforce them.Methods: Among all the drugs used at our hospital, we identified those with warnings on the package insert about driving motor vehicles and classified them in accordance with “The Drug Administration Guidance Criteria Regarding the Driving of Vehicles,” created by our hospital on the basis of descriptions on the package insert and the level of risk of taking drugs.  We then standardized the warnings about driving motor vehicles while taking drugs, throughout our hospital.Results: Of the 1,416 drugs used at our hospital, we identified 294 (21%) with warnings about driving motor vehicles on the package insert, and more than half of these (158 drugs) had warnings about the prohibition of driving motor vehicles on the package insert.  As a result of classifying the drugs according to “The Drug Administration Guidance Criteria Regarding the Driving of Vehicles,” we identified 53 drugs with warnings about the prohibition of driving motor vehicles.  By the classification of the level of risk of taking drugs while driving motor vehicles and the hospital-wide standardization of the warnings about driving motor vehicles while taking drugs, we are now able to provide drug administration guidance in the form of warnings that are customized to the level of risk of using each drug.Conclusion: These measures have clarified the level of risk of taking each drug and warnings about driving motor vehicles while taking them.  In the future, we intend to cooperate with local pharmacies to intervene in the prescription of drugs outside well as inside hospitals.
著者
和田 正義 亀田 藤雄 斎藤 征道
出版者
公益社団法人 計測自動制御学会
雑誌
計測自動制御学会論文集 (ISSN:04534654)
巻号頁・発行日
vol.49, no.4, pp.417-424, 2013 (Released:2013-04-26)
参考文献数
15
被引用文献数
2

This paper presents a study on steering control algorithm for a joystick car drive system. The joystick drive system allows a handicapped person to drive a car by using a joystick with small force and short stroke. However, a wrong joystick operation, such as a sudden and wide steering, when a vehicle running in a very high speed results in a car accident quite easily. The other hand, quite sensitive steering control is required around the center of steering angle when a car runs along a straight line. When parking a car, a large steering angle provides easier parking maneuvering to a driver. To realize these requirements and solve some problems, we propose a steering control method with variable steering sensitivity and steering limitation based on a vehicle velocity. First, a dynamic model of a car running with rotation to define a risk for rollover of a car. From the dynamic model, we get limitation of steering angles as a function of the vehicle velocity. The limitation function is verified by the drive test taken by the real van running on the public road including highway and parking lot. The control method is successfully implemented on a microcomputer based controller for the joystick car drive system.
著者
Mingzhe Jin Masakatsu Murakami
出版者
The Behaviormetric Society of Japan
雑誌
Behaviormetrika (ISSN:03857417)
巻号頁・発行日
vol.20, no.1, pp.63-76, 1993 (Released:2006-05-26)
参考文献数
9
被引用文献数
2 10 9

Identifying the elements that make up an author's characteristic writing style is one of the keys to determining the authorship or authenticity of a literary composition. The present study, which constitutes a preliminary attempt to uncover such a key, focuses on the placement of commas in sentences, a matter that has hitherto been neglected, analysing the characters that commas follow in works by four authors. It is concluded that the placement of commas differs from writer to writer and may therefore be considered one of the features that makes up an individual literary style, thus providing valuable information for verifying authenticity and speculating on questions of authorship.
著者
田村 俊世 小川 充洋 依田 美紀子 戸川 達男
出版者
一般社団法人 電気学会
雑誌
電気学会論文誌C(電子・情報・システム部門誌) (ISSN:03854221)
巻号頁・発行日
vol.118, no.7-8, pp.993-998, 1998-07-01 (Released:2009-10-02)
参考文献数
12
被引用文献数
3

The aim of this study was to provide adequate home health monitoring in the home by using fully automated biosignal measurement to support daily health care and to improve quality of life. We attempted to develop a home health monitoring system that did not provide any restrictions during sleep. bathing or elimination. A set of room containing a bedroom. bathroom. and toilet room was constructed. The system consisted of monitoring devices and a computer terminal for collecting data. The data were automatically collected from the monitoring devices placed at the bed, bath, and toilet and were transferred to a data terminal in the bedroom and stored for further analysis. The data acquisition system is now being used for seven days and data are collected without any trouble.
著者
Hayato Tada Masa-aki Kawashiri Taiji Yoshida Ryota Teramoto Atsushi Nohara Tetsuo Konno Akihiro Inazu Hiroshi Mabuchi Masakazu Yamagishi Kenshi Hayashi
出版者
日本循環器学会
雑誌
Circulation Journal (ISSN:13469843)
巻号頁・発行日
pp.CJ-15-0999, (Released:2015-12-02)
参考文献数
39
被引用文献数
7 62

Background:It has been shown that serum lipoprotein(a) [Lp(a)] is elevated in familial hypercholesterolemia (FH) with mutation(s) of the LDL receptor (LDLR) gene. However, few data exist regarding Lp(a) levels in FH with gain-of-function mutations of the PCSK9 gene.Methods and Results:We evaluated 42 mutation-determined heterozygous FH patients with aPCSK9gain-of-function mutation (FH-PCSK9, mean age 52, mean LDL-C 235 mg/dl), 198 mutation-determined heterozygous FH patients with aLDLRmutation (FH-LDLR, mean age 44, mean LDL-C 217 mg/dl), and 4,015 controls (CONTROL, mean age 56, mean LDL-C 109 mg/dl). We assessed their Lp(a), total cholesterol, triglycerides, HDL-C, LDL-C, use of statins, presence of hypertension, diabetes, chronic kidney disease, smoking, body mass index (BMI) and coronary artery disease (CAD). Multiple regression analysis showed that HDL-C, use of statins, presence of hypertension, smoking, BMI, and Lp(a) were independently associated with the presence of CAD. Under these conditions, the serum levels of Lp(a) in patients with FH were significantly higher than those of the CONTROL group regardless of their causative genes, among the groups propensity score-matched (median Lp(a) 12.6 mg/dl [IQR:9.4–33.9], 21.1 mg/dl [IQR:11.7–34.9], and 5.0 mg/dl [IQR:2.7–8.1] in the FH-LDLR, FH-PCSK9, and CONTROL groups, respectively, P=0.002 for FH-LDLR vs. CONTROL, P=0.002 for FH-PCSK9 vs. CONTROL).Conclusions:These data demonstrate that serum Lp(a) is elevated in patients with FH caused by PCSK9 gain-of-function mutations to the same level as that in FH caused by LDLR mutations.
著者
Yoshitsune Miyagi Mariko Harada-Shiba Takao Ohta
出版者
一般社団法人 日本動脈硬化学会
雑誌
Journal of Atherosclerosis and Thrombosis (ISSN:13403478)
巻号頁・発行日
pp.31666, (Released:2015-10-27)
参考文献数
18
被引用文献数
4

Familial hypercholesterolemia (FH) is characterized by a high level of low-density lipoprotein cholesterol (LDL-C) and is inherited as an autosomal dominant trait. We report 4-year-old dichorionic diamniotic twins (boy and girl) with FH who presented with multiple xanthomas on the face, both knees, both feet, and buttocks. Family history revealed vertical transmission of hypercholesterolemia from father to patients, thereby suggesting dominant inheritance. Lipid data of their mother did not match the criteria of FH. However, lipid data of maternal grandmother and maternal sister matched the criteria of FH. LDL receptor gene analysis of the family revealed that their father was heterozygous for a missense mutation, L547V, their mother was heterozygous for a nonsense mutation, C675X, and patients were compound heterozygous for L547V and C675X. After 10 months of treatment with pitavastatin (2 mg/day) and ezetimibe (10 mg/day), LDL-C decreased from 595 mg/dL to 267 mg/dL in the boy and from 530 mg/dL to 182 mg/dL in the girl. These findings suggest that lipid-lowering therapy with statin may be considered in pediatric patients with compound heterozygous FH (hetero FH) before inducing LDL apheresis, and gene analysis for true diagnosis in pediatric patients with multiple xanthomas should be considered, though they appear to be hetero FH from the family history and lipid data of parents.
著者
アカングベ ジョーンズ アデボーラ コモラフェ ソラ エマヌエル オデュワイエ ムイワ オラリンデ
出版者
産業医科大学、産業医科大学学会
雑誌
Journal of UOEH (ISSN:0387821X)
巻号頁・発行日
vol.37, no.3, pp.169-175, 2015-09-01 (Released:2015-09-12)
参考文献数
17

ナイジェリアのクワラ州において,作業の危険性の農業従事者の生産性へおよぼす影響について自覚的評価に基づいて調べた.多段階無作為抽出法を用いて全160名の回答者を選別した.実証分析のためのピアソンの積率相関係数解析と共に頻度や割合などの記述的統計手法を用いて分析を行った.調査の結果,共通の農業生産物はトウモロコシ,ヤムイモ,キャッサバであった.また,共通して多い作業上の危険は農具による切傷/傷害,蚊刺しに起因するマラリア,および全身性疼痛であり,農具による傷害および全身性疼痛が農業生産性に大きな影響を及ぼしていることが明らかになった.農業従事者の社会-経済学的特徴と自覚されている農業生産性への作業の危険性の影響との間には,ピアソンの積率相関係数を用いた解析においては有意な相関は認められなかった.これらの結果にもとづき,作業(農業)における危険,とくに全身性の疼痛が,農業生産性に負の効果をもたらすと結論する.この研究からは,政府と関係機関が農業従事者に保護具の使用法を訓練する普及員を通して保護具を安価で提供し,農業労働者に保護具の使用を督励することが推奨され,農業従事者自身が良好な健康状態を維持するための健康管理について教育を行うことが公衆衛生関係者には求められる.
著者
石川 奈緒 伊藤 歩 海田 輝之
出版者
一般社団法人 日本原子力学会
雑誌
日本原子力学会和文論文誌 (ISSN:13472879)
巻号頁・発行日
vol.13, no.3, pp.87-93, 2014 (Released:2014-08-15)
参考文献数
26

Radionuclide contamination from the nuclear accident at the Fukushima Daiichi Nuclear Power Plant has been found in sewage sludge ash produced in eastern Japan. When such contaminated waste contains less than 8,000 Bq/kg radiocesium, it is being disposed in controlled landfill sites. In order to assess the possible spread of the radionuclides by their leaching from the landfill sites, it is important to know the leaching behavior of the radionuclides from the sewage sludge ash and factors influencing the leaching behavior. In this study, leaching experiments using stable Cs and Sr were conducted for sewage sludge ash under several conditions to investigate effects of chemical composition of leachate, pH, and solid/liquid ratio on Cs and Sr leaching behaviors. In the pH range from 6 to 12, the leaching ratio of Cs or Sr was less than 5.2 or 0.21%, respectively. Additionally, the leaching ratio of Sr decreased with increasing pH of the leachate. In contrast, the higher the pH in the leachate was, the higher the leaching ratio of Cs was. Finally, possible radionuclide leaching from contaminated sewage sludge ash and then radionuclide concentrations in an actual landfill leachate were assessed. It could be suggested that 90Sr leaching from the landfill site had the least effect on the environment, whereas 134+137Cs leaching needed to be taken into account for spreading radioactive materials from the landfill site to the environment.
著者
Caroline Wasonga Shingo Inoue James Kimotho Kouichi Morita Juliette Ongus Rosemary Sang Lillian Musila
出版者
国立感染症研究所 Japanese Journal of Infectious Diseases 編集委員会
雑誌
Japanese Journal of Infectious Diseases (ISSN:13446304)
巻号頁・発行日
vol.68, no.5, pp.410-414, 2015 (Released:2015-09-18)
参考文献数
16
被引用文献数
1 6

Chikungunya (CHIK) is a mosquito-borne viral disease. In the 2004 CHIK outbreak in Kenya, diagnosis was delayed because of the lack of accurate diagnostics. Therefore, this study aimed to develop and evaluate an in-house IgM-capture enzyme linked immunosorbent assay (ELISA) (in-house ELISA) for the detection of chikungunya virus (CHIKV) infections. Anti-CHIKV antibodies were raised in rabbits, purified and conjugated to horseradish peroxidase. These anti-CHIKV antibodies and cell-culture derived antigen were used to develop the ELISA. To validate the in-house ELISA, 148 patient sera from the 2005 Comoros CHIK outbreak were tested with centers for disease control and prevention (CDC) IgM-capture ELISA (CDC ELISA) and focus reduction neutralization test (FRNT) as reference assays. The in-house ELISA had a sensitivity of 97.6% and specificity of 81.3% compared to the CDC ELISA and a sensitivity of 91.1% and specificity of 96.7% compared to FRNT. Furthermore, 254 clinically suspected dengue patient samples from Eastern Kenya, collected in 2013, were tested for CHIKV IgM using the in-house ELISA. Out of the 254 samples, 26 (10.2%) were IgM positive, and of these 26 samples, 17 were further analyzed by FRNT and 14 (82.4%) were positive. The in-house ELISA was able to diagnose CHIKV infection among suspected dengue cases in the 2013 outbreak.
著者
Tianan Yang Mingjing Zhu Xiyao Xie
出版者
(公社)日本産業衛生学会
雑誌
Journal of Occupational Health (ISSN:13419145)
巻号頁・発行日
pp.15-0114-OA, (Released:2015-10-20)
被引用文献数
1 42

Objectives: The aim of this study was to identify the determinants of presenteeism, taking health and individual factors into account. Methods: A quantitative analysis applying structural equation modelling analysis was conducted on the basis of secondary data from the Health and Retirement Survey (2008 wave), which measured presenteeism and its determinants. Results: Stress-related factors at work (β = -0.35, p< 0.001), individual factors (β = -0.27, p< 0.001), and health (β = 0.24, p< 0.001) were significantly related to presenteeism. Individual factors were found to be directly correlated with stress-related factors at work (β =0.22, p< 0.001). Significant indirect effects between stress-related factors at work and presenteeism (Sobel z = -6.61; p< 0.001) and between individual factors and presenteeism (Sobel z = -4.42; p< 0.001), which were mediated by health, were also found. Overall, the final model accounted for 37% (R2 = 0.37) of the variance in presenteeism. Conclusions: Our study indicates some important and practical guidelines for employers to avoid the burdens of stress-related presenteeism among their employees. These findings could help select target factors in the design and implementation of effective presenteeism interventions in the aging working population.