著者

土居 正城 加藤 哲文

出版者

日本学校メンタルヘルス学会

雑誌

学校メンタルヘルス = Journal of school mental health (ISSN:13445944)

巻号頁・発行日

vol.20, no.1, pp.68-78, 2017

著者

早瀬 文孝

出版者

公益社団法人 日本農芸化学会

雑誌

化学と生物 (ISSN:0453073X)

巻号頁・発行日

vol.31, no.9, pp.592-601, 1993-09-25 (Released:2009-05-25)

参考文献数

24

被引用文献数

2 2

著者

横山青娥 著

出版者

長崎書店

巻号頁・発行日

vol.下巻, 1943

著者

by Erich F. Schmidt

出版者

University of Chicago Press

巻号頁・発行日

1931

著者

佐藤 徹

出版者

Japanese Society for the Science of Design

雑誌

日本デザイン学会研究発表大会概要集

巻号頁・発行日

pp.8, 2014 (Released:2014-07-04)

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環境を重視した地域政策として近年最も成功した住宅開発地域であるドイツのフライブルク、ヴォーバン地区を取材し調査、分析することによりこの地方都市がいかにして世界的な環境都市として認識されるに至ったかを明らかにする。

著者

谷口 邦彦

出版者

研究・イノベーション学会

雑誌

年次学術大会講演要旨集

巻号頁・発行日

vol.32, pp.136-139, 2017-10-28

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一般講演要旨

著者

石原 慶一

出版者

研究・イノベーション学会

雑誌

年次学術大会講演要旨集

巻号頁・発行日

vol.32, pp.134-135, 2017-10-28

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一般講演要旨

著者

山田 剛治 鈴木 俊之 高柳 大樹 藤田 和央

出版者

一般社団法人 日本航空宇宙学会

雑誌

日本航空宇宙学会論文集 (ISSN:13446460)

巻号頁・発行日

vol.57, no.670, pp.426-436, 2009 (Released:2009-11-25)

参考文献数

22

被引用文献数

1 1

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A free piston double diaphragm shock tube with 70 × 70mm cross-section at test section was newly developed for the purpose of investigating nonequilibrium phenomena behind a shock wave. This paper presents the performance of the shock tube and the measurement system newly developed. Experimental investigation to clarify its characteristics was conducted for various operational parameters, such a rupture pressure of the first diaphragm and initial pressures of the low pressure tube, the high pressure tube, and the compression tube. Based on the characteristics experiment, a performance map of the shock tube was obtained by changing the operation parameters. The result shows that the shock tube is capable of generating the shock layer corresponding to the super orbital reentry flight conditions. The newly developed measurement system enables us to obtain the spatial distribution of spectra behind a shock wave with high spatial and time resolution. A description of the measurement system and typical examples of the measured spectra are presented.

著者

齊藤 和貴 岡安 孝弘

出版者

明治大学文学部心理社会学科

雑誌

明治大学心理社会学研究 (ISSN:18844618)

巻号頁・発行日

no.5, pp.22-32, 2009

著者

梅田 博之

出版者

研究・イノベーション学会

雑誌

年次学術大会講演要旨集

巻号頁・発行日

vol.30, pp.1061-1064, 2015-10-10

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2015年8月現時点において産学連携関連の研究は、大規模データ分析を用いたものを初めとするマクロ的な視点で論じている研究が多い。それとは対照的に、実際的・現場的ミクロな視点を持ったものは少ない。そこで本論文は私がデータ分析システムを開発・販売する会社(AIC社)を起業した経験をまとめた。内容としては起業を計画するところから、製品化断念までの実体験をまとめた。また失敗の原因の考察、考察から見えてきた製品化成功のための一仮説を掲載している。

出版者

誠文堂新光社

雑誌

農耕と園芸 (ISSN:13458833)

巻号頁・発行日

vol.71, no.7, pp.96-99, 2016-07

著者

中村 一樹 佐藤 友徳 田谷 英次

出版者

日本気象学会

雑誌

大会講演予講集

巻号頁・発行日

vol.104, 2013

著者

眞子 直弘

出版者

一般社団法人 日本リモートセンシング学会

雑誌

日本リモートセンシング学会誌 (ISSN:02897911)

巻号頁・発行日

vol.37, no.1, pp.39-44, 2017

著者

田端 信廣

出版者

Societas Philosophiae Doshisha

雑誌

同志社哲学年報 (ISSN:03871584)

巻号頁・発行日

no.36, pp.1-39, 2013-09

著者

廣田 直美

出版者

青山学院大学

巻号頁・発行日

2016

著者

Yuki YAMANASHI Shohei NISHIMOTO Nobuyuki YOSHIKAWA

出版者

The Institute of Electronics, Information and Communication Engineers

雑誌

IEICE TRANSACTIONS on Electronics (ISSN:09168516)

巻号頁・発行日

vol.E99-C, no.6, pp.692-696, 2016-06-01

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A single-flux-quantum (SFQ) arithmetic logic unit (ALU) was designed and tested to evaluate the effectiveness of introducing dynamically reconfigurable logic gates in the design of a superconducting logic circuit. We designed and tested a bit-serial SFQ ALU that can perform six arithmetic/logic functions by using a dynamically reconfigurable AND/OR gate. To ensure stable operation of the ALU, we improved the operating margin of the SFQ AND/OR gate by employing a partially shielded structure where the circuit is partially surrounded by under- and over-ground layers to reduce parasitic inductances. Owing to the introduction of the partially shielded structure, the operating margin of the dynamically reconfigurable AND/OR gate can be improved without increasing the circuit area. This ALU can be designed with a smaller circuit area compared with the conventional ALU by using the dynamically reconfigurable AND/OR gate. We implemented the SFQ ALU using the AIST 2.5kA/cm2 Nb standard process 2. We confirmed high-speed operation and correct reconfiguration of the SFQ ALU by a high-speed test. The measured maximum operation frequency was 30GHz.

著者

清水 万紀子

出版者

公益社団法人 日本薬学会

雑誌

YAKUGAKU ZASSHI (ISSN:00316903)

巻号頁・発行日

vol.129, no.11, pp.1351-1356, 2009 (Released:2009-11-01)

参考文献数

23

被引用文献数

1 2

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Individual differences of drug-metabolizing enzymes are important determinants for the metabolic fate of chemicals. This article focuses on polymorphic human flavin-containing monooxygenase 3 (FMO3) and dietary-derived trimethylamine. Malodorous trimethylamine is generally converted to odorless trimethylamine N-oxide by liver microsomal FMO3. Trimethylaminuria is caused by functional disorder of FMO3. In this study mutations of the FMO3 gene were examined in self-reported Japanese trimethylaminuria subjects that showed low FMO3 metabolic capacity in urine tests. Nine novel polymorphisms in the FMO3 gene were discovered in self-reported Japanese volunteers. Functional analyses of recombinant FMO3 proteins suggested that these FMO3 gene mutations were one of the causal factors for decreased FMO3 function resulting in trimethylaminuria. Inter-individual variations of FMO3-mediated microsomal oxygenation activities, levels of FMO3 protein and FMO3 mRNA, and its modification in liver microsomes from Japanese samples were observed. Both genetic polymorphisms in the 5′-upstream of the FMO3 gene and some hormonal changes related to menstruation may be causal factors for inter- and/or intra- individual expression levels of FMO3. To assess the palliative cares, it was found that absorbed levels of trimethylamine in vivo would be possibly controlled by selection of precursor foods like fish containing a variety of trimethylamine amounts. These lines of evidence suggest that individual differences of FMO3 are important determinants for the metabolic fate of dietary-derived trimethylamine.

著者

Koichiro Suzuki Takahiro Yamada Keiko Yamazaki Masato Hirota Narumi Ishihara Mizuki Sakamoto Daisuke Takahashi Hideki Iijima Koji Hase

出版者

Japan Society for Cell Biology

雑誌

Cell Structure and Function (ISSN:03867196)

巻号頁・発行日

pp.17022, (Released:2018-01-18)

被引用文献数

9

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Inflammatory bowel disease (IBD) is a refractory disease of the gastrointestinal tract that is believed to develop in genetically susceptible individuals. Glycosylation, a type of post-translational modification, is involved in the development of a wide range of diseases, including IBD, by modulating the function of various glycoproteins. To identify novel genes contributing to the development of IBD, we analyzed single nucleotide polymorphisms (SNPs) of glycosylation-related genes in IBD patients and identified MAN2A1, encoding alpha-mannosidase II (α-MII), as a candidate gene. α-MII plays a crucial, but not exclusive, role in the maturation of N-glycans. We also observed that intestinal epithelial cells (IECs), which establish the first-line barrier and regulate gut immunity, selectively expressed α-MII with minimal expression of its isozyme, alpha-mannosidase IIx (α-MIIx). This led us to hypothesize that IEC-intrinsic α-MII is implicated in the pathogenesis of IBD. To test this hypothesis, we generated IEC-specific α-MII-deficient (α-MIIΔIEC) mice. Although α-MII deficiency has been shown to have a minimal effect on N-glycan maturation in most cell types due to the compensation by α-MIIx, ablation of α-MII impaired the maturation of N-glycans in IECs. α-MIIΔIEC mice were less susceptible to dextran sulfate sodium-induced colitis compared with control littermates. In accordance with this, neutrophil infiltration in the colonic mucosa was attenuated in α-MIIΔIEC mice. Furthermore, gene expression levels of neutrophil-attracting chemokines were downregulated in the colonic tissue. These results suggest that IEC-intrinsic α-MII promotes intestinal inflammation by facilitating chemokine expression. We propose SNPs in MAN2A1 as a novel genetic factor for IBD. Key words: inflammatory bowel disease, alpha-mannosidase II, intestinal epithelial cell, N-glycosylation

著者

佐藤 年明 SATOU Toshiaki

出版者

三重大学教育学部

雑誌

三重大学教育学部研究紀要, 自然科学・人文科学・社会科学・教育科学

巻号頁・発行日

vol.62, pp.229-234, 2011-03-31

出版者

専修大学歴史学会

雑誌

専修史学 (ISSN:03868958)

巻号頁・発行日

no.16, pp.p176-187, 1984-12