著者

前田 剛司 坂田 洋

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.28, no.5, pp.495-501, 2002-10-10 (Released:2011-03-04)

参考文献数

10

被引用文献数

1 2

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The injection auto ample dispensing equipment, combined with an ordering system, was established at the Kasugai Municipal Hospital. This equipment enabled us to give a patient one injection per prescription unit out of approximately 400 different prescriptions. In the hospital, this is now available in every ward except in the ICU. This system has been functioning favorably since its installation : it accurately produces prescriptions for injections, written instructions for injections, and labels for infusion bottles. Due to these traits, the people who work in the wards think highly of this system.A safety control system to prevent medical mishaps has been established because drug duplications and interactions with all types of medications can be checked with the injection auto ample dispensing equipment before administering injections to patients. However, we still have some problems to solve : namely, we still have to check the incompatibility and maintain the stability in mixing injection drugs.

著者

高柳 理早 山田 安彦 河野 真理子 中村 均 佐藤 均 伊賀 立二

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.28, no.5, pp.489-494, 2002-10-10 (Released:2011-03-04)

参考文献数

5

被引用文献数

1 1

---

The new Good Clinical Practice (GCP) guidelines, which were based on ICH-GCP, were enforced in Japan in April 1997. These guidelines recommend that pharmacists play the role of managers of investigational drugs and also as cooperators (clinical research coordinator) in the performance of clinical trials. In this study, we carried out a survey of the attitude of the new graduate pharmacists (the group of graduates in the 1998 fiscal year and a group of graduates in the 1999 fiscal year) on clinical trials. After the first questionnaire, we lectured the students on GCP and performed clinical trials, and then the second questionnaire was conducted two months later. The group of graduates in the 1999 fiscal year had more opportunities to come in contact with information on clinical trials than the group in the 1998 fiscal year. Both groups knew that new GCP guidelines had been established, but they did not understand the details. Some of them had a negative impression concerning clinical trials. The lectures improved their knowledge and impression on the practice of clinical trials. After the lecture, over 90% of them thought that pharmacists should manage investigational drugs and provide information on these drugs for the rational practice of clinical trials. Furthermore, in 60% or more of the students, an improvement in the consciousness of evaluating the safety and efficacy of investigational drugs regarding the pharmacist's role was found.

著者

湯元 良子 高野 幹久

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.28, no.5, pp.484-488, 2002-10-10 (Released:2011-03-04)

参考文献数

7

---

Clinical research as well as basic research is one of the important aspects for the development of clinical pharmacy. In clinical pharmacy research, like research in medicine, it is desirable to find and investigate problems on clinical pharmacotherapy and to utilize the findings of such results in the therapy. In order to promote such clinical pharmacy research, collaboration between hospital or community pharmacies and pharmaceutical universities is very important, because the former usually does not have enough space, equipment, or pharmacists to do the research, and the latter usually does not have chance to find the problems in clinical pharmaco-therapy. In the present study, we carried out a questionnaire survey concerning clinical pharmacy research, in order to clarify the present situations and needs in hospital or community pharmacy in Hiroshima prefecture. The results indicated that many pharmacists in hospital as well as community pharmacy feel that it is necessary to do clinical pharmacy research to understand and clarify the problems they found in clinical pharmacotherapy. In addition, though many of them are either not doing or can not do clinical pharmacy research under the present situation, they are interested in collaborating with pharmaceutical universities. These results offer important information in promoting clinical pharmacy research based on the collaboration between hospital or community pharmacies and pharmaceutical universities.

著者

平井 みどり 八木 敬子 木口 敏子 長嶺 幸子 冨田 尚子 上田 久美子 平井 由華 加藤 史恵 寺岡 麗子 大塚 誠 岩川 精吾 松田 芳久

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.28, no.5, pp.461-467, 2002-10-10 (Released:2011-03-04)

参考文献数

5

被引用文献数

5 5

---

Effective communication is central to patient-centered care in the successful practice of pharmacy. As well as communication skills, a pharmacist should acquire an effective presentation technique to establish interpersonal communication at a more than purely on a verbal level. Most undergraduates of Kobe Pharmaceutical University undergo practical training in hospitals or community pharmacies. It is essential for students to acquire communication skills in order to derive the full benefit from the practical training. We introduced a presentation and communication program at the pre-practical training stage. In the presentation component, students were asked to make a presentation on eight different aspects of a certain drug; in the communication component, students took part in a session where they learned and discussed interview skills, non-verbal communication, open-ended questioning and effective communication. Questionnaires answered by the undergraduates suggested that this training course had made a strong impression on them and had served as a useful guide to acquiring the presentation and communication skills essential in pharmaceutical care.

著者

松元 美香 大谷 道輝 馬島 裕子 並木 路広 假家 悟 内野 克喜

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.28, no.5, pp.450-455, 2002-10-10 (Released:2011-03-04)

参考文献数

5

被引用文献数

2 1

---

It is important that laboratory data to be constantly checked according to described package inserts during usage of medicines. However, many hepatic and renal disorders were reported to have strong adverse reactions for prescription drugs. We investigated the necessity of hepatic and renal function checks in package inserts for 3300 prescription drugs. As a result, the number of drugs which recommended checks on hepatic and renal functions were 240 (7.3%) and 209 (6.3%) respectively. The described expression or place regarding checks of hepatic and renal functions on package inserts were various types of unclear information to doctors and pharmacists. We thus found that the present style of package inserts unapprehensive to the necessity of hepatic and neral function checks. So, in our hospital, we decided to provide a list of drugs that required hepatic and renal function checks during administration of drugs.These findings suggest that the need of hepatic and renal functions monitoring during the administration of drugs by the establishment of a new Clinical Checks item in the package inserts is therefore necessary.

著者

影山 恵美子 古岩 清子 木村 りつ子 折井 孝男 伊賀 立二

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.28, no.5, pp.435-442, 2002-10-10 (Released:2011-03-04)

参考文献数

3

---

The Ministry of Health and Welfare (the present, Ministry of Health, Labour and Welfare) has begun to report the recall information of medical supplies (in short, recall information) on the home page of the pharmaceutical information provision by the Organization for Pharmaceutical Safety and Research since April 1 st, 2001. However, all recall information on the home page appears the day after the official publication. In case of medical devices in comparison to pharmaceuticals, it takes a longer time to be reported on the home page. However, such recall information is valuable, because it is the only information source, which medical institutions can obtain up-to-date information spontaneously.At Uwajima City Hospital, from May 2001, the pharmacists have participated in a safety management program regarding new medical devices or medical materials.In order to keep all medical materials safe, pharmacists check the recall information regularly and provide them to the clinical site for risk management. Not only the medical institutions but also the dealers have begun to make practical use of such recall information. However, no system for using such information has yet been established among them. According to the regulations of recall information, a contact system from the maker to the dealer has been established. However, the first information of medical devices is always obtained through the home page. The way to obtain the information has been changing.Needless to say, the “Internet” is nowadays the main media for the communications all over the world. Accurate information must be speedy and reliable. The rational use of such information on the Internet is therefore urgently needed.

著者

後藤 伸之 吉村 直人 萱野 勇一郎 渡辺 享平 林 美由 青池 美穂 白波瀬 正樹 脇屋 義文 政田 幹夫

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.28, no.4, pp.401-406, 2002-08-10 (Released:2011-03-04)

参考文献数

5

被引用文献数

1

---

A heparin lock is technique performed in order to prevent blood coagulation in the needle detained in the vessel, or a catheter. In Japan, when we perform a heparin lock, a heparin injection is diluted with physiological salt solution before use. We need to use prefilled syringes with diluted heparin. We received a sample of this product. We investigated the user-friendliness of the product. From our results, the prefilled syringe with the diluted heparin was found to be useful. Furthermore, when we use the prefilled syringe with diluted heparin, patient safety is increased.

著者

伊藤 雄大 髙田 麻季 飯田 真之 宇田 篤史 住吉 霞美 秋山 恵里 丸上 奈穂 丹田 雅明 野間 千尋 山本 和宏 五百蔵 武士 木村 丈司 西岡 達也 久米 学 槇本 博雄 矢野 育子

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.44, no.5, pp.236-243, 2018-05-10 (Released:2019-05-10)

参考文献数

18

被引用文献数

2

---

Team-based learning (TBL) is an active learning method which has been designed to help students solve problems both by themselves and as a team. In this study, TBL was introduced in the journal club (gathering to read and discuss medical papers) for pharmacists, and its effectiveness was compared with that of a traditional lecture. The subjects, 29 pharmacists at Kobe University Hospital, were randomly allocated to the lecture group and TBL group. The pre-test was conducted two months before the journal club, and the post-tests were conducted immediately and one month after the journal club. There was no significant difference in the background data of the pharmacists between the lecture group and the TBL group. The score differences between the pre-test and the post-test immediately after the journal club were not significant (11.4 ± 2.3 points (mean ± SD) in the TBL group, 8.8 ± 4.2 points in the lecture group, P = 0.14). The post-test scores immediately after the journal club in the TBL group (19.6 ± 0.5 points) were significantly higher compared with those in the lecture group (17.8 ± 1.5 points) (P < 0.01), and the learning effect provided by TBL tended to be maintained one month after the TBL. In conclusion, TBL was an alternative method of the ordinal lecture and may be a useful learning method for pharmacists to read medical papers critically compared with the ordinal lecture.

著者

石田 和久 中尾 承司 佐多 照正 岩下 佳敬 本田 香奈恵 山下 カオリ 黒木 久知 田辺 元 山崎 芳人 上田 勝

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.28, no.3, pp.259-262, 2002-06-10 (Released:2011-03-04)

参考文献数

8

被引用文献数

2 2

---

In order to examine the fungistatic action of TPN fluids against Candida abicans, which was clinically isolated and chosen as a model fungus because of its high risk of infection, we attempted to compare the TPN products commonly used at our hospital. Furthermore, we also investigated the effects of pH and sodium bisulfite (NaHSO3) on this action. Under the respective conditions of a lower pH or higher concentration of NaHSO3, the fungistatic action was weakly recognized, however, under the both conditions (lower pH and higher concentration of NaHSO3), a remarkable fungistatic action was observed.

著者

菅原 満 荻野 修 宮崎 勝巳

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.28, no.3, pp.256-258, 2002-06-10 (Released:2011-03-04)

参考文献数

4

被引用文献数

2 1

---

Zyvox® (linezolid), an oxazolidinone-class synthetic antibacterial agent, has been approved for the treatment of vancomycin-resistant Enterococcus faecium infections. Although there are three forms of this drug, including injection, tablets and oral suspension, presently available overseas, only injection and tablets have so far been approved in Japan. It is possible to use ground tablets as an oral suspension. However, the quality including the stability of linezolid in such a suspension has not yet been studied. In this study, we therefore, examined the stability of linezolid in a suspension of ground tablets and the characteristics of such a suspension. The solubility of linezolid was low, and approximately 85% of linezolid was suspended in a solid phase. Linezolid was stable in the suspension, and there were no differences in the pH for up to 24 hours. However, precipitation occurred rapidly after the ground tablets had been suspended. The concentration of linezolid in the upper layer of the suspension decreased to half of the initial concentration in 15 min.In conclusion, Zyvox® was found to be stable and therefore is considered suitable to be ground and used in an oral suspension. Such suspensions should be re-suspended just before use, especially when the suspension is pre-constituted.

著者

高橋 昌也 新井 克明 本間 真人 鈴木 勝 佐藤 信一 幸田 幸直

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.28, no.2, pp.172-175, 2002-04-10 (Released:2011-03-04)

参考文献数

9

被引用文献数

2 1

---

To investigate the description of the expiration date and manufacturing number on the drug packages, “pillow” packages and “heat-seal” packages, the questionnairing was carried out to pharmaceutical companies. Fifty-six drugs consisting of three hundred thirty-seven items, with sales of over 10 billion yen in 1998, were investigated at the corresponding 26 companies. The recovery rate of the questionnaire from the company was 100%, and the answer for all questions was also perfect. Three hundred fourteen items (93%) have had description regarding the manufacturing number and/or the expiration date on the heat-sealed packages. The manufacturing number took precedence over the expiration date. Of 269 pillow packages, 69 items (26%) have had description of manufacturing number and/or expiration date on the pillow package. There were 41 products (12%) that the company did not guarantee an expiration date being described on the box container when the packages were taken out from the box container.As a result, the description of the manufacturing number and expiration date on the packages, “pillow” and “heat-seal”, is still not complete even though the companies guarantee the expiration date when the drugs were stored with these packages. Since the information of the expiration date is necessary for the appropriate management of tablet and capsule products, it is required to describe manufacturing number and expiration date on every drug package including “pillow” and “heat-seal” packages.

著者

西山 祐美 北田 徳昭 関戸 聡子 小林 睦 渡 雅克 内田 享弘 松山 賢治 黒田 和夫

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.28, no.2, pp.184-191, 2002-04-10 (Released:2011-03-04)

参考文献数

10

被引用文献数

4 4

---

A four-week practical hospital training course for undergraduates at Takarazuka Municipal Hospital has been conducted since 1998. The curriculum at our hospital consists of three elements, i.e., lectures on hospital pharmacy, the dispensing service and the clinical pharmacy service. Regarding the clinical pharmacy service, a case study had token a long time for the purpose of learning the actual services. In this study, we compared the results of the new curriculum with those of previous curriculums to establish a more effective and practical curriculum for undergraduates. Our curriculum showed no significant difference with the findings of other reports. Next, we investigated the student' s awareness by questionnaire. The results showed that most students developed on increased awareness of the pharmacist' s daily practice by the end of the practical training course. However it also showed a tendency that their interests in pharmacy practice differed according to their future courses and the university they were studying.From these results, further progress therefore appears to still be obtainable by increasing the cooperation between pharmaceutical universities and hospital pharmacies. In addition, it was considered that our curriculum should be further improved by better meeting the needs of students during the practical training course.

著者

花輪 剛久 青木 歩 花輪 和己 手塚 春樹 荒井 千春 河田 圭司 鈴木 正彦 中島 新一郎

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.28, no.2, pp.176-183, 2002-04-10 (Released:2011-03-04)

参考文献数

11

被引用文献数

2 2

---

The stability of powdery dosage forms of drugs prepared by unsealing the packages was investigated. For 247 articles purchased by the Yamanashi Medical University Hospital, the variables related to the evaluation of stability after unsealing these packages and investigating the contents based of an “Interview Form”. A longterm preservation test was carried out on 153 items (94%), and the mean length of the test was about 36 months. The acceleration and the severity tests were carried out using 17 items (10.4%) and 114 items (69.9%), respectively. The mean conditions of the acceleration test was 40°C/6 months, which agreed with the guidelines proposed by the “Drug Manufacturing Guidelines”. On the other hand, for the severity test, certain conditions for the evaluation could not be arranged, and testing was carried out under various conditions. In order to improve the efficiency of dispensing and the quality of life for patients, a further increased standardization of the testing conditions is recommended.

著者

田中 睦子 河野 健治 花輪 剛久 鈴木 正彦 中島 新一郎

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.28, no.2, pp.152-156, 2002-04-10 (Released:2011-03-04)

参考文献数

12

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Di-2-ethylhexyl Phthalate (DEHP) was reported to dissolve from a polyvinyl chloride (PVC) administration tube during the infusion of an injection fluid containing a solvilizing agent, soybean oil or lecithin, etc. This paper describes the behavior of DEHP dissolution from PVC tubes during enteral tube feeding. The DEHP concentration was determined using HPLC. After the passage the ENSURE LIQUID® (EL) solution through the PVC tube, DEHP was dissolved in the EL solution. The EL solution is one type of enteral nutrition. This dissolution pattern was similar to that of injection fluid containing a solvilizing agent, in which the DEHP concentration in the EL solution increased linearly over time at first and thereafter reached a plateau. 170 μg of the DEHP was dissolved after 200mL of the EL solution had passed through the PVC administration set (the drip conditions were 25°C, 100mL/hr, tube length 115cm and inner diameter 0.3cm). The amount of DEHP which dissolved into the solution depended on the temperature (25-40°C), and no clear difference was observed between the PVC tubes (administration tube, feeding tube). In addition, the amount of DEHP that dissolved into the solution varied depending on the type of enteral nutrition.

著者

小池 香代 江崎 哲夫 樋田 治夫 矢崎 蓉子 水野 裕之 竹内 敏明 前田 徹 大橋 千草 荒川 由佳 長崎 淳 黒田 純子 服部 隆宏 浅野 知子 近藤 勝弘 丹村 貴之 山田 芳敬 野間 秀一 藤田 幸子 長谷川 信策

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.28, no.2, pp.116-125, 2002-04-10 (Released:2011-03-04)

参考文献数

19

---

In Nagoya City University Hospital, a two-week training program for senior students in pharmacy training was carried out up until 1999. The large majority of senior students took a passive role in this pharmacy training course and therefore did not understand that importance of such training. Therefore, the pharmacy training period was extended from two-weeks to four-weeks in 2000. We thus evaluated what differences there were after the training was increased from two-weeks to four-weeks.The four-week training program was found to increase student motivation toward the pharmacy training. Our survey concluded that approximately 69 % of all senior students were interested in pharmacy training and 75% of senior students understood the role of the pharmacist. In addition, 87% of senior students had an improved image of pharmacists after the new pharmacy training. The reason for such an increase was that the senior students gained a better understanding of the reasons for training and also obtained practical experience in pharmaceutical care. These findings suggest that the four-week training program with self-learning exercises was useful for normally passive senior students. It also enabled hospital pharmacists to make an even greater contribution to the pharmacy training program.

著者

長谷部 啓子 矢田 眞理子 石井 文由

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.28, no.2, pp.144-151, 2002-04-10 (Released:2011-03-04)

参考文献数

23

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Due to an emergency warning from a pharmaceutical company, we evaluated the procedure of providing drug information to medical staffs. The warning was made regarding DEHP, which is a plasticizer of PVC eluted in etoposide injections, and intravenous transfusion sets made from PVC are used in such injections. We tried to determine whether or not any leaching of DEHP occurred during etoposide injection. Moreover, we investigated the properties of DEHP, the mechanism of DEHP leaching from PVC, and also inspected other medicines that may also have leaching of DEHP in PVC administration sets. As a result, no clinical evidence was found to support this urgent notice. However, passing through several years, related information became gradually clear. Therefore, in the information asked for quick offer, it was suggested that gradual and continuous information service becomes indispensable especially.

著者

高良 恒史 大西 憲明 橋詰 勉 金澤 治男 横山 照由

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.28, no.1, pp.57-62, 2002-02-10 (Released:2011-03-04)

参考文献数

8

被引用文献数

5 5

---

In 1996, the Department of Clinical Pharmacy at the Education and Research Center of Kyoto Pharmaceutical University was established to enrich the education program of pharmaceutical health care and sciences, and to also be used as a pre-training program for undergraduates before taking part in externships at hospitals or pharmacies. In the following year, the training center of clinical pharmacy (a simulated pharmacy) was also founded, and has since been used for the practical training of pharmaceutical health care and sciences for third-year undergraduate students. We herein describe our findings of an unregistered questionnaire survey of the undergraduate students' view, while also evaluating and discussing the effectiveness of this training program.Almost all students considered undergoing the practical training to be useful and necessary for them, because their scores before and after the training were 4.24 and 4.56 points on a scale of 5 point maximum, respectively. The students also evaluated each part of the training program, with mean values before and after the practice 3.75-4.01 and 3.70-4.39, respectively. The students did voice various opinions regarding the practical training program. Consequently, the students are satisfied with the practical training programs at present, however, we will have to continually improve such programs to better meet the students needs.

著者

千葉 薫 宮崎 勝巳 板谷 幸一 佐藤 誠二 高橋 保志 松原 和夫

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.28, no.1, pp.41-46, 2002-02-10 (Released:2011-03-04)

参考文献数

6

---

Hospital pharmaceutical preparations (HPP) are used in patients whose complications are not well controlled by the commercially available drugs or injections. The use of HPP is effective when HPP are proposed through clinical pharmacy services. A questionnaire was developed to evaluate the use of HPP and then was sent to 49 hospital pharmacies who belong to the Hokkaido Association for Hospital Pharmaceuticals.As a result, 32 institutions replied to questionnaire, thus indicating a recovery rate of 65%. HPP, including mixtures of injectable drugs, were used at 30 out of 32 institutions. According to the questionnaires, 11 hospitals manufactured 24 HPP which were used during clinical pharmacy services. Half of these preparations were used to care for adverse symptoms, such as stomatitis, induced by the cancer chemotherapy.The use of HPP prepared by clinical pharmacy services is closely related to patient's symptoms. The practical use of HPP is not only considered to improve drug compliance and the QOL of patients, but are also thought to enhance the general capabilities of pharmacists in clinical pharmaceutical practice.

著者

梅村 雅之 伊東 亜紀雄 鍋島 俊隆

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.28, no.1, pp.16-21, 2002-02-10 (Released:2011-03-04)

参考文献数

17

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In hematopoietic cell transplantation, amphotericin B (AMPH) syrup is widely used for the prevention of local fungal infections in the intraoral and gastrointestinal tracts. However, the dosage compliance tends to be poor due to its unpleasant taste. We therefore developed a candy preparation for AMPH in order to improve compliance. In this study, we examined the thermostability, stability under storage and the dissolution pattern of AMPH in this preparation. The oral contents of AMPH after administration in the candy preparation were also measured in healthy volunteers. A low calorie sweetener was heated to melt and cooled down to several temperatures (150-190°C). After cooling, AMPH syrup or powder grinding tablets were added (9 mg/ 3 g/piece : the final contents). The results of a thermostability examination show that AMPH was not affected at 150°C, however, it tended to be damaged at higher temperatures. When one piece of AMPH candy preparation was administered for 30 sec to healthy volunteers, the oral concentration of AMPH is higher than 100μg/mL for 10 min, which is more than the minimal inhibitory concentration (MIC) for Candida albicans. Furthermore, the results of a texture test using healthy volunteers indicate that the taste, i.e., flavor, feel on the tongue, etc of the candy preparation made from syrup was superior to that made from powder. These results suggest that a sufficient oral concentration of AMPH to prevent fungal infection was obtained in this candy preparation. As a result, this candy preparation may improve not only the dosage compliance but also the QOL of the patients.

著者

二神 幸次郎 西原 茂樹 定金 典明 谷口 律子 荒木 博陽 川崎 博巳 五味田 裕

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.27, no.6, pp.589-593, 2001-12-10 (Released:2011-03-04)

参考文献数

4

被引用文献数

5 5

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During a three-week long practical training program for pharmacy students at our hospital, senior pharmacy students had a one-day observation of pharmacists performing new drug investigations. Using a questionnaire survey we investigated whether the observation of the work of clinical research coordinator (CRC) influenced the student's understanding of the new drug investigation procedures. The observation of CRC's work consisted of counseling/interviewing prior to the doctor's consultation and visiting a clinical laboratory to observe new drug investigations. The items evaluated were impressions of the clinical investigation of new drugs, precautions for preparing investigational drugs, understanding the new Good Clinical Practice (GCP) guidelines and other important aspects in the clinical investigation. Each group consisted of 26 students. Only 10 out of 26 students observed counseling/interviewing before the doctor's consultation with CRC. The impression of the clinical investigation procedure in group I, which observed the CRC's work was more favorable than in group II, which did not observe it. The understanding of the important aspects of the clinical investigation procedures in group I was markedly better than in group II. We thus consider that the observation of the CRC work is very useful for students not only to learn new drug investigation procedures, but also to understand the meaning of the new GCP guidelines.