著者
福澤 美佐 嘉村 基樹 国貞 和恵 萩原 淳 本田 久美代 持永 早希子 矢富 義信 原 周司 小野 信文 黒田 健
出版者
日本医療薬学会
雑誌
病院薬学 (ISSN:03899098)
巻号頁・発行日
vol.24, no.5, pp.499-507, 1998-10-10
被引用文献数
2

A questionnaire survey the patient's views regarding drug information was carried on 941 outpatients from April 24 to May 10, 1997 at Fukuoka University Hospital. As a resutlt that drug information and compliance counseling was found to have been given by physicians (73%). Pharmacists (9%), both(7%) and nurses (3%). Thirty-two% of the patients showed a good understanding of the counseling and could correctly identify their medicines. Most patiens who did not understand their medications very well wanted written information about the effects, side effects and drug interactions of the prescribed medicines. These patients requested physicians (75%), Pharmacists ( 13%) and both (9%) to give the drug information. These results indicate that the present drug counseling to the outpatients is not sufficient. Increasted efforts by pharmacists are therefore still needed to enable patients to obtain appropriate information and thereby improve the overall effectiveness of drug therapy.
著者
遠原 大地 後藤 玲子 伊東 弘樹 森 一生 鳥越 繁治 中川 辰二 因泥 栄一郎 武山 正治
出版者
日本医療薬学会
雑誌
医療薬学 (ISSN:1346342X)
巻号頁・発行日
vol.30, no.4, pp.255-260, 2004-04-10
被引用文献数
2 2

We developed a support system for pharmaceutical counseling services using a handheld computer loaded with HS-WIN. HS-WIN is standard software for pharmaceutical counseling services that is compatible with Windows X-P, 2000 and 98. Our support system is linked to the pharmacy network system of Oita University Hospital. It enables various kinds of information to be retrieved from the pharmacy network system and shown on the display of a handheld computer. This includes drug information, names, sex, birth dates, heights and weights of patients as well as clinical department and ward-related information. The handheld computers are the VAIO PCG-U 1 and PCG-U 3 (SONY, Inc.) and they are used at the bedside. To evaluate the effectiveness of our system,we measured the time required for the management of medication histories and patient counseling records for three wards.The system was able to reduce the time required per patient by an average of 34 minutes.
著者
小山 和弘 小笠原 伸子 青野 美弘 梶原 博視 関口 久紀
出版者
日本医療薬学会
雑誌
医療薬学 = Japanese journal of pharmaceutical health care and sciences (ISSN:1346342X)
巻号頁・発行日
vol.27, no.1, pp.24-28, 2001-02-10
被引用文献数
2

We investigated the relationship between the serum vancomycin concentration and the initial dosage regimen. Furthermore, we evaluated the dose and dosage interval for the therapeutic level (trough< 10μg/mL, peak 25-40μg/mL) and the toxic level (trough>15μg/mL).<BR>The percentage of the concentration within the therapeutic level was 0% and the percentage over the toxic level was 71% regarding a vancomycin dose of 500mg every 6 hours. The percentage of the concentration within the therapeutic level was 0% and the percentage over a toxic level was 23% regarding a dose of 500 mg every 12 hours. The percentage of the concentration within therapeutic level was 0% and the percentage over the toxic level was 33% regarding a dose of 1, 000mg every 12 hours. The percentage of the concentration within the therapeutic level was 21% and the percentage over the toxic level was 11% regarding a dose of 1, 000mg every 24 hours. The percentage of the concentration within the therapeutic level was 33% and the percentage over the toxic level was 10% regarding a dose of 1, 500mg every 24 hours. As a result, a dose of 1, 500mg every 24 hours was found to achieve the most appropriate therapeutic levels. On the other hand, a dose of 500mg every 6 hours showed a poor percentage of the concentration over the toxic level.
著者
喜屋 武典 大城 進 亀谷 浩昌 藤本 勝喜 赤崎 満 古謝 景春
出版者
日本医療薬学会
雑誌
病院薬学 (ISSN:03899098)
巻号頁・発行日
vol.19, no.1, pp.18-23, 1993-02-20

The use of a reagent for digoxin assay of fluorescence polarization immunoassay with TDX analyzer in the determination of serum deslanoside concentration was studied. Deslanoside calibrators with the concentration of 0.0-6.0ng/ml were prepared. The assay item for digitoxin was used for deslanoside after modification of the parameters. The coefficients of variation of within-run assay and between-run assay in this method were less than 9% at various concentrations tested. By use of a ultrafiltration method, the protein binding percent of deslanoside was determined to be zero or very small. In a patient with renal and hepatic failures, the half life (t1/2) and the apparent volume of distribution (Vd) were calculated to be 131 hours and 4.1l/kg after intravenous administration of deslanoside, respectively. On the other hand, an equation of Y=1.25X+0.08 was obtained from a correlation between digoxin concentration (X) given by normal digoxin assay and concentration of deslanoside (Y). Therefore, with a simple method, one can calculate the deslanoside concentrations.
著者
太田 伸 長井 克浩 全田 浩 牧野 公博
出版者
日本医療薬学会
雑誌
病院薬学 (ISSN:03899098)
巻号頁・発行日
vol.18, no.3, pp.196-203, 1992-06-20
被引用文献数
1

The present study was performed to estimate the efficacy of antirust and disinfection of new compounds (P1-E, P2-E, P3-E, P4-E, P2-PG1, P3-PG1, P4-PG1) as shown in Table 1 in comparison with commercial disinfectants [chlorhexidine digluconate (CHX), benzalkonium chloride (BAC) and alkyldiaminoethylglycine hydrochloride (ADE)]. Antirusting effects of new compounds were evaluated by counting the numbers of rusts on the ten pins. The antirusting effects of new compounds were higher than those of CHX, BAC and ADE. Rusts were produced after 6hr in the case of BAC. Effects of new compounds and disinfectants against clinical isolated pathogenic microorganisms were determined by minimum inhibitory concentration (MIC). Antimicrobial activities of P1-E, P2-E, P3-E and P4-E were equivalent to that of BAC or ADE, while effects of disinfection of P2-PG1, P3-PG1 and P4-PG1 were higher than that of BAC or ADE. Compatibilities of new compounds with various disinfectants or sodium lauryl sulfate (SLS) were tested in each combination, P1-E, P2-E, P3-E, P4-E and P4-PG1 had good compatibilities to the various disinfectants and the SLS in the case of each combination. These results indicated that the new compounds were very useful as antirusty disinfectants.
著者
吉山 友二 尾鳥 勝也 厚田 幸一郎 矢後 和夫 藤金 治雄 緒方 憲太郎 二神 幸次郎
出版者
日本医療薬学会
雑誌
医療薬学 (ISSN:1346342X)
巻号頁・発行日
vol.33, no.4, pp.365-369, 2007-04-10
被引用文献数
2

Elcatonin injection is used for the treatment of osteoporosis in Japan. In order to compare the original product with generic versions, we measured the elcatonin content and amounts of impurities in both using high performance liquid chromatography, and observed changes in content with time under the conditions of light exposure and shaking. We found that elcatonin content and amounts of impurities varied among the generics and that changes in content with time under the above conditions for some generics were greater than the changes for the original product. These results suggest that some generic products should not be considered to be equivalent to the original product.