出版者

特定非営利活動法人 日本火山学会

雑誌

火山 (ISSN:04534360)

巻号頁・発行日

vol.67, no.3, pp.app1, 2022 (Released:2022-10-27)

著者

吉田 春彦

出版者

一般社団法人 日本物理学会

雑誌

秋の分科会予稿集 1984.4 (ISSN:2433118X)

巻号頁・発行日

pp.44, 1984-09-10 (Released:2018-03-22)

著者

Noriko Kaneko Yoshikazu Nishino Yuri Ito Tomoki Nakaya Seiki Kanemura

出版者

Japan Epidemiological Association

雑誌

Journal of Epidemiology (ISSN:09175040)

巻号頁・発行日

pp.JE20220066, (Released:2022-07-16)

参考文献数

35

被引用文献数

1

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Background: Previous studies have shown that socioeconomic factors are associated with cancer incidence and stage at diagnosis; however, relevant findings in Japan are limited. We examined the association between socioeconomic status and cancer incidence, stage at diagnosis, and detection status by screening, as assessed by the areal deprivation index (ADI), using population-based cancer registry data.Methods: A total of 79,816 cases including stomach, colorectal, lung, female breast, and cervical cancer diagnosed in Miyagi Prefecture between 2005 and 2010 were analyzed. After calculating the ADI at the place of residence in each case, we examined the association between quintiles of ADI and age-adjusted incidence rates of all stages and advanced stages by sex and site using Poisson regression analysis. The association between the ADI and the proportion of screen-detected cancers was also examined using logistic regression analysis.Results: The age-adjusted incidence rates of all sites and lung cancer in men and lung cancer and cervical cancer in women tended to increase significantly in areas with a higher ADI. The age-adjusted incidence rates of advanced-stage cancers were significantly higher for all sites and lung cancer in both sexes, and stomach and colorectal cancer in men. The proportion of screen-detected cancer tended to be significantly lower in areas with a higher ADI for stomach and colorectal cancer in men.Conclusion: Our results indicate that socioeconomic disparities may affect cancer incidence and early diagnosis in Japan. These results suggest the importance of cancer control measures targeting people with low socioeconomic status in Japan.

出版者

福井県丹生郡豊尋常高等小学校

巻号頁・発行日

1936

著者

杤山 修 高須 亜紀 池田 孝夫 木村 英雄 佐藤 正知 長崎 晋也 中山 真一 新堀 雄一 古屋 廣高 三頭 聰明 山口 徹治

出版者

一般社団法人 日本原子力学会 バックエンド部会

雑誌

原子力バックエンド研究 (ISSN:18847579)

巻号頁・発行日

vol.5, no.1, pp.3-19, 1998-09-01 (Released:2014-10-01)

参考文献数

44

被引用文献数

3 5

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放射性廃棄物の地層処分の安全性評価において,現在用いられている核種移行モデルは主として,固体物質による遅延効果を収着分配係数 Kd を用いて評価している. しかしながら,収着はその機構が未だ十分解明されていない現象であるため,移行モデルに Kd を用いるにあたっては,いくつかの注意が必要となる. このような問題は,収着が固体と水の界面あるいはその近傍で起こる不均一系の反応であることと,核種の移行媒体である地質媒体の物理的性質や化学的性質が一様でないことに起因している. 本論文では,収着は固体と水の界面あるいはその近傍で起こる現象であるという理解のもとに,Kd を用いて記述できる収着現象の範囲について考え,さらに原位置での核種移行の評価に対する Kd による記述の妥当性と適用性について考察した.

著者

上林 陽治

出版者

公益財団法人 地方自治総合研究所

雑誌

自治総研 (ISSN:09102744)

巻号頁・発行日

vol.47, no.514, pp.26-56, 2021 (Released:2021-08-30)

著者

小宮山量平 [ほか] 著

出版者

日本エディタースクール出版部

巻号頁・発行日

1971

著者

望月 雅和

出版者

日本経営倫理学会

雑誌

日本経営倫理学会誌 (ISSN:13436627)

巻号頁・発行日

vol.18, pp.223-233, 2011-03-31 (Released:2017-08-08)

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Problems concerning working women and child-rearing, as well as economic problems, attract strong attention from the aspects of childcare, social welfare, clinical psychology and ethics. The social understanding of "child-rearing by mothers" as a private problem has deepened also as a public problem. The publication of "Collection of articles and documents on women's work before the war" is a result of my research to date, collaborative research with people involved in the Women's and Minor's Bureau. This is related to the analysis of the history of ideas of working women and child-rearing. In this present study, discussion is especially based on the viewpoint of the history of ideas in postwar Japan. Taking publicness and changing gender roles into consideration, I argue that the important viewpoints for analyzing reality include keeping an eye to human rights, citizens' and human dignity and grasping domestic and international correlative dynamics.

著者

豊田 実

出版者

公益社団法人 高分子学会

雑誌

高分子 (ISSN:04541138)

巻号頁・発行日

vol.10, no.8, pp.685-688, 1961-07-20 (Released:2011-10-11)

参考文献数

9

著者

森 豪大 籔谷 祐介 宋 俊煥

出版者

公益社団法人 日本都市計画学会

雑誌

都市計画論文集 (ISSN:09160647)

巻号頁・発行日

vol.57, no.3, pp.933-940, 2022-10-25 (Released:2022-10-25)

参考文献数

24

被引用文献数

1

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本研究では、高岡市に居住する高校生を対象にアンケート調査を実施し、どのような源泉がシビックプライドを醸成し、将来の定住意識を高めるかという一連の流れを明らかにした。源泉は「地域環境」、「文化・産業」、「食・自然」、「歴史」の4つの因子で構成され、シビックプライドの構成要素は「参画」、「アイデンティティ」、「愛着」、「持続願望」の4つであることを提示した。また、共分散構造分析の結果、高校生における将来の定住意識は、シビックプライドの構成要素の一つである「愛着」によって形成され、その「愛着」は「地域環境」と「文化・歴史」の源泉によって醸成されることが明らかになった。高校生にとっては、身近に利用できる公園・緑地環境や、祭でのコミュニケーション、小中学校において伝統文化や産業に触れる地域教育が将来の定住意識に寄与することを推察した。

著者

武 覚超

雑誌

武庫川女子大学生活美学研究所紀要 (ISSN:09169709)

巻号頁・発行日

vol.30, pp.189-208, 2020-11-30

著者

吉川 晟弘 後藤 龍太郎 朝倉 彰

出版者

日本甲殻類学会

雑誌

CANCER (ISSN:09181989)

巻号頁・発行日

vol.31, pp.1-4, 2022-08-01 (Released:2022-08-24)

参考文献数

6

著者

Atsushi Ogasawara Hiroki Doi Taei Matsui Etsuko Tokunaga Masao Amakawa Hidehiko Akiyama

出版者

Fujita Medical Society

雑誌

Fujita Medical Journal (ISSN:21897247)

巻号頁・発行日

pp.2022-021, (Released:2022-10-28)

参考文献数

20

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Objectives: Agaritine (AGT) is a hydrazine-containing compound derived from the mushroom Agaricus blazei Murill. We previously reported the antitumor effect of AGT on hematological tumor cell lines and suggested that AGT induces apoptosis in U937 cells via caspase activation. However, the antitumor mechanism of AGT has not been fully understood.Methods: Four hematological tumor cell lines (K562, HL60, THP-1, H929) were used in this study. The cells were incubated in the presence of 50 μM AGT for 24 h and analyzed for cell viability, annexin V positivity, caspase-3/7 activity, mitochondrial membrane depolarization, cell cycle, DNA fragmentation, and the expression of mitochondrial membrane-associated proteins (Bax and cytochrome c).Results: In HL60, K562, and H929 cells, AGT reduced cell viability and increased annexin V- and dead cell-positive rates; however, it did not affect THP-1 cells. In K562 and HL60 cells, caspase-3/7 activity, mitochondrial membrane depolarization, and expression of mitochondrial membrane proteins, Bax and cytochrome c, were all increased by AGT. Cell cycle analysis showed that only K562 exhibited an increase in the proportion of cells in G2/M phase after the addition of AGT. DNA fragmentation was also observed after the addition of AGT.Conclusions: These results indicate that AGT induces apoptosis in K562 and HL60 cells, like U937 reported previously, but showed no effect on THP-1 cells. It was suggested that AGT-induced apoptosis involves the expression of Bax and cytochrome c via mitochondrial membrane depolarization.

著者

Satoshi Yamamoto Kazuo Inui Yoshiaki Katano Hironao Miyoshi Takashi Kobayashi Yoshihiko Tachi

出版者

Fujita Medical Society

雑誌

Fujita Medical Journal (ISSN:21897247)

巻号頁・発行日

pp.2022-011, (Released:2022-10-28)

参考文献数

22

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Objectives: We aimed to determine when a coexisting pseudocyst was likely to complicate the nonsurgical treatment of pancreatolithiasis.Methods: We treated 165 patients with pancreatolithiasis nonsurgically between 1992 and 2020, including 21 with pseudocysts. Twelve patients had a single pseudocyst less than 60 mm in diameter. Pseudocysts in the other nine patients had diameters of at least 60 mm or were multiple. The locations of pseudocysts along the length of the pancreas varied from the area with stone involvement to the pancreatic tail. We compared the outcomes in these groups.Results: We found no significant differences in pain relief, stone clearance, stone recurrence, or the likelihood of adverse events between pseudocyst groups or between patients with vs without pseudocysts. However, 4 of 9 patients with large or multiple pseudocysts required transition to surgical treatment (44%) compared with 13 of 144 patients with pancreatolithiasis and no pseudocyst (9.0%) (P=0.006).Conclusions: Patients with smaller pseudocysts typically underwent nonsurgical stone clearance successfully with few adverse events, similar to findings in patients with pancreatolithiasis and no pseudocysts. Pancreatolithiasis complicated by large or multiple pseudocysts did not cause more adverse events but was more likely to require transition to surgery compared with pancreatolithiasis without pseudocysts. In patients with large or multiple pseudocysts, early transition to surgery should be considered when nonsurgical treatment is ineffective.

著者

近藤 孝悌

出版者

公益財団法人 日本醸造協会

雑誌

日本釀造協會雜誌 (ISSN:0369416X)

巻号頁・発行日

vol.58, no.2, pp.102-105, 1963-02-15 (Released:2011-11-04)

著者

吉田 重厚

出版者

公益財団法人 日本醸造協会

雑誌

日本釀造協會雜誌 (ISSN:0369416X)

巻号頁・発行日

vol.72, no.3, pp.188-192, 1977-03-15 (Released:2011-11-04)

参考文献数

48

著者

宮森麻太郎 著

出版者

鍾美堂書店

巻号頁・発行日

1917

著者

簔原 豪人 内山 将伸 緒方 憲太郎 二神 幸次郎

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.37, no.11, pp.649-652, 2011 (Released:2012-11-10)

参考文献数

11

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Using a formula for calculating the glomerular filtration rate (GFR) for Japanese announced in 2009, individual patients' GFRs can be predicted by inversely correcting the formula with body surface area. In this study, we investigated the influence of the dissociation between the GFR normally employed to calculate the dose and inversely corrected GFR on carboplatin (CBDCA)-related thrombocytopenia. In a group with grade 3 or higher thrombocytopenia, the dissociation between the GFRs used to calculate the dose of CBDCA was significantly greater. Also, in an analysis of thrombocytopenia-related factors, including concomitant anti-cancer agents, the only significant difference was that regarding GFR dissociation.These results suggest that the introduction of the inversely corrected GFR for accurate calculation of the GFR and setting of CBDCA doses is useful in decreasing the incidence of serious thrombocytopenia.

著者

山田 肖子

出版者

国際開発学会

雑誌

国際開発研究 (ISSN:13423045)

巻号頁・発行日

vol.25, no.1-2, pp.17-33, 2016-11-15 (Released:2019-09-27)

参考文献数

31

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Based on the analysis of the discourse in the process of consensus building toward a post-2015 education agenda, this paper will examine if commonly accepted notion of “global governance” represents the reality or is in need of revision.The paper examines the interplay among actors who took part in the discourse via different channels of global governance, including both formal and informal channels. Most of the forums and entities established as part of the global governance structure are composed of representatives from UN or UNESCO member states, civil society organizations (CSOs), and UN agencies. However, each of these categories has diverse constituent groups; representing these groups is not as straightforward a task as the governance structure seems to assume. Therefore, based on interviews and qualitative text analysis, this paper will introduce major groups of actors and their major issues of concern, decision-making structure, mode of communication, and relationship with other actors. Then, based on an understanding of the characteristics of the various channels and actors, it will present the structural issues which determined the nature of discourse and the educational issues that emerged as the shared concerns of the “education community”.What was the post-2015 discourse for the so-called education community, which in itself has an ambiguous and virtual existence? The key words post-2015 and post-EFA provide us with an opportunity to untangle how shared norms and codes of conduct were socially constructed in the vertical and horizontal spaces of discourse at the global, regional, and national levels.Given that the most of such processes toward constructing the norms and decision-making framework happened outside of the formal United Nations-led mechanism, the paper argues that the global governance theories based on the relationships between states and their representative “international bodies” are losing relevance to the global dynamics of consensus building.

著者

Miku Miyoshi Tadao Inazu Hirotoshi Tamura Ken Izumori Kazuya Akimitsu Isao Kimura

出版者

Japanese Society for Food Science and Technology

雑誌

Food Science and Technology Research (ISSN:13446606)

巻号頁・発行日

pp.FSTR-D-21-00280, (Released:2022-10-28)

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For rare sugars to be used in fermented foods, their effect on microorganisms used in soy sauce brewing must first be determined. Here, when soy sauce-brewing microorganisms were cultured with a mixture of four rare sugars (D-allulose, D-allose, D-tagatose, and D-sorbose) with D-glucose, growth was not inhibited when the percentage of each rare sugar did not exceed 60 % of the carbon source. D-Tagatose was not inhibitory, even at 100 % of the carbon source, and it had the same effect as D-glucose on lactic acid fermentation by Tetragenococcus halophilus. To confirm soy sauce can be brewed with rare sugars, we conducted a small-scale brewing study with a rare sugar syrup (RSS). After aerobic fermentation by the yeast, the relative composition of each rare sugar remaining in the brew was 95 % allulose, 34 % allose, 68 % tagatose, and 84 % sorbose of the respective original concentration. Analyses of the final product found that acidic bitterness and acidic bitter aftertaste of the soy sauce were suppressed compared to the control, and this was attributed to a decrease in the amount of basic amino acids, which might be related to bitterness, during brewing.