著者

河井 保博

出版者

日経BP社

雑誌

日経Internet solutions (ISSN:13476580)

巻号頁・発行日

no.75, pp.57-59, 2003-10

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携帯電話から使えるモバイル決済サービスが,新しいフェーズを迎えている。赤外線通信機能を使ったクレジット決済や,携帯電話に配信した2次元コードを使うコンビニ決済である。コンテンツ利用料だけでなく,携帯サイトなどで購入した高額な物品の支払いにも利用できる。ただ,実店舗でしか使えないサービスがあるなど,利用場面はまちまちだ。

著者

中川智尋 山田渉 土井千章 稲村浩 太田賢 鈴木誠 森川博之

雑誌

マルチメディア、分散協調とモバイルシンポジウム2013論文集

巻号頁・発行日

vol.2013, pp.1116-1122, 2013-07-03

著者

藤木 大介

出版者

日本読書学会

雑誌

読書科学 (ISSN:0387284X)

巻号頁・発行日

vol.59, no.2, pp.72-79, 2017-05-22 (Released:2017-06-08)

参考文献数

13

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Some readers are unable to accurately comprehend texts and tend to distort the meaning based on social or moral desirability. To investigate the characteristics of readers who avoid reading based on moral schema, this study administered the Reader Belief Questionnaire, a critical thinking disposition scale, and a task in which participants had to evaluate the appropriateness of concluding sentences in the following situations: (1) appropriate sentences which were derived from the earlier context, (2) inappropriate sentences, and (3) morally biased sentences. The results of the experiment indicated that readers who scored high on the “inquiry mind” factor of the critical thinking scale and had a critical thinking disposition could distinguish appropriate conclusions from the moral biased ones. This indicates that an inquisitive mind with the desire for a wider variety of information affects the process of evaluating information while deriving conclusions, and encourages unbiased and appropriate reading.

著者

武藤 桃太郎 武藤 瑞恵 石川 千里 井上 充貴 升田 晃生 高橋 裕之 萩原 正弘 青木 貴徳 橋本 道紀 稲葉 聡 矢吹 英彦

出版者

THE JAPANESE ASSOCIATION OF RURAL MEDICINE

雑誌

日本農村医学会雑誌 (ISSN:04682513)

巻号頁・発行日

vol.63, no.1, pp.49-56, 2014

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症例1は85歳, 女性。近医にてCEA9.2ng/mlと高値を指摘され当科紹介となった。CT検査, 超音波検査で虫垂部に嚢胞状腫瘤を認めた。注腸造影検査では盲腸下端に半球状の表面平滑な隆起性病変を認め, 虫垂は造影されなかった。虫垂粘液嚢腫の診断で盲腸部分切除術を施行し, 術後CEAは4.7ng/mlと正常化した。 症例2は74歳, 女性。高血圧, 高脂血症で当科通院中にCEA12.3ng/mlと高値を示し, CT検査, 超音波検査で虫垂部に嚢胞状腫瘤を認めた。注腸造影検査では盲腸に粘膜下腫瘍様隆起を認め, 虫垂は造影されなかった。虫垂粘液嚢腫の診断で盲腸部分切除術を施行し, 術後CEAは1.5ng/mlと正常化した。 いずれも病理検査で虫垂粘液嚢胞腺腫と診断され, 免疫染色ではCEA陽性であった。

著者

原恵著

出版者

恒星社厚生閣

巻号頁・発行日

1975

著者

原恵著

出版者

恒星社厚生閣

巻号頁・発行日

1996

著者

堀 史郎

出版者

近畿大学工業高等専門学校

雑誌

熊野工業高等専門学校紀要

巻号頁・発行日

vol.8, pp.49-63, 1991-03-20

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This paper shows the supporting rates to cabinets and parties from November 1955 to September 1990 using the result of the poll conducted by the Asahi. It also shows the numbers of succeesful candidates of each party and voting percentages to them in the House of Representatives.

著者

城 由紀子

出版者

文化学園大学

雑誌

文化女子大学紀要. 人文・社会科学研究 (ISSN:09197796)

巻号頁・発行日

vol.15, pp.37-49, 2007-01

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1993年のカナダ下院総選挙において大敗を喫した進歩保守党と保守第1 党の地位に着いた改革党,後のカナダ同盟が,保守勢力の分裂,混迷を乗り越え「右派連合」の新しい保守党として再生後,2006年総選挙において13年ぶりの保守政権誕生を果した。この新保守政権誕生の要因は,自由党長期政権がケベック州での連邦政府広報費不正流用問題で信頼を失ったなかで,1987年の改革党結成以降分裂状態であった保守2 政党が前回2004年の総選挙前に一体化を成し遂げ新生保守党として地歩を固めたことにある。加えて,前回選挙では保守色故に敬遠された保守党党首ハーパー(Stephen Harper)が,イメージ変革に成功し国民から首相として一応の信任を得たためである。本稿はハーパーの保守党党首への道程を辿り,2006年総選挙を2004年総選挙と比較し,前回総選挙での失敗を乗り越えたハーパー保守党政権誕生を分析する。

著者

北村 陽子

出版者

早稲田大学大学院文学研究科

雑誌

早稲田大学大学院文学研究科紀要. 第2分冊 (ISSN:13417525)

巻号頁・発行日

vol.51, pp.83-99, 2005

著者

張 国良

出版者

日中医学協会

雑誌

日中医学 (ISSN:09126287)

巻号頁・発行日

vol.21, no.3, pp.8-11, 2006-09-25

著者

廣重 畫

出版者

野田茂政

巻号頁・発行日

1880

巻号頁・発行日

1946-10

著者

酒井 昭四郎 大蔵 律子

出版者

公益社団法人 日本分析化学会

雑誌

分析化学 (ISSN:05251931)

巻号頁・発行日

vol.15, no.5, pp.507-509, 1966-05-05 (Released:2009-06-30)

参考文献数

3

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Since condensed chain phosphoric acids have a titratable strong-acid hydrogen for each phosphorus atom and a titratable weak-acid hydrogen corresponding only to terminal phosphorus atoms, the average number of phosphorous atoms per chain (polymerization degree) can be calculated from titrant volume consumed for two inflexion points on pH titration curve.In the determination of polymerization degree of chain polyphosphates, pH titration was carried out after phosphates had been changed to acid type by ion exchange resin. The values obtained by this method showed a good agreement with those calculated from chemical analysis of Na/P.The method will be applicable to routine analysis for production control of chain polyphosphates.

著者

Weber Maria Steffen Hans-M. Haupt Walter F. Becker Karin Brunner Richard Mahrle Gustav Borberg Helmut

出版者

日本アフェレシス学会

雑誌

日本アフェレシス学会雑誌 (ISSN:13405888)

巻号頁・発行日

vol.16, no.1, pp.115-125, 1997

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Extracorporeal elimination therapy of metabolic diseases may be taken into consideration if the substrate to be removed is present in the circulation in an elevated concentration and if the endogenous synthe-sis rate does not exceed the amount of re-moval. Systemic amyloidoses are characte-rized by the presence of specific protein pre-cursor molecules in the serum. Polymeriza-tion leads to the formation of fibrils which are deposited as amyloid in the extracellular space. Depending on the variables of the disease to be treated, it may generally be possible to delay its progression, achieve a halt in progression or even initiate regression of amyloid deposition. Two patients, a mother and her son, 54 and 25 years of age, with familial amyloidosis due to the transthyretin met30 variant (Por-tuguese type), after a disease duration of 9 and 6 years, respectively, received regular plasma exchanges in two-week intervals over a period of P/2 years. Patients' plasma was exchanged at volumes of 155% and replaced by 5% human albumin solution. Transthyretin levels were reduced by 50 - 70% during each plasma exchange procedure. Clinical, neurological, opthalmological, laboratory, histological, and electron microscopical examinations were performed prior to, and after one year of plasma exchange therapy. The overall results indi-cate only slight progression in the older pa-tient and stability in the younger patient. Athird patient, 56 years of age, with immunglobulin-type (AL) amyloidosis due to monoclonal gammopathy of unknown significance, with cardiac involvement and rapid deterioration of renal function under chemotherapy was treated initially by plasma exchange over a period of 1 1/2 years without further cytotoxic treatment, and subsequently by Ig adsorption using protein A or anti-IgG columns. Para-protein levels were reduced to 20-25% of the pretreatment values by plasma exchange on two consecutive days. Renal function, clinical and echo-cardiographical signs of cardiac failure remained stable. Our experience having patients with two different forms of systemic amyloidosis sufficiently is encouraging to discuss the possible therapeutic role of extracorporeal elimination in delaying the progression of amyloidosis.

著者

飯田 鼎

出版者

慶應義塾経済学会

雑誌

三田学会雑誌 (ISSN:00266760)

巻号頁・発行日

vol.56, no.5, pp.440(64)-447(71), 1963-05

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書評

著者

武藤 毅 近藤 隆史 柴田 拓伸 曽根 大紀 藤田 達也 桐生 稔 木越 英夫 小鹿 一 山田 靜之

出版者

天然有機化合物討論会実行委員会

雑誌

天然有機化合物討論会講演要旨集

巻号頁・発行日

vol.37, pp.230-235, 1995

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Constituents of the Japanese sea hare Dolabella auricularia collected in Mie Prefecture, Japan were examined by using bioassay, and new cytotoxic depsipeptides, dolastatins G (1) and H (14) and isodolastatin H (15) were isolated. Dolastatin G (1) showed cytotoxicity against HeLa-S_3 cells with an IC_<50> of 1.0μg/mL. On the basis of 2D NMR technique, dolastatin G (1) has proved to be a 35-membered cyclic depsipeptide which consists of a hexapeptide and two new hydroxy acids. The absolute stereochemistry of the hexapeptide moiety was determined by the chiral HPLC analysis of amino acids obtained by acidic hydrolysis of dolastatin G (1). The absolute stereochemistry of two hydroxy acid parts was determined by the enantioselective synthesis of two corresponding fragments obtained by degradation of dolastatin G (1). For the purpose of confirming the stereostructure of dolastatin G (1), synthetic studies on dolastatin G (1) have been carried out. Three subunits, 7, 10, and 11, were synthesized, coupling of which gave seco acid 13. The synthesis of dolastatin G (1) from seco acid 13 is in progress. A 1:1 mixture of dolastatin H (14) and isodolastatin H (15) showed potent cytotoxicity against HeLa-S_3 cells with an IC_<50> of 0.00381μg/mL. On the basis of spectroscopic data, dolastatin H (14) has proved to be a linear tetrapeptide which contains two unusual amino acids and is esterified at the C-terminus by the primary hydroxyl group of 3-phenyl-1,2-propanediol. Isodolastatin H (15) is the structural isomer of dolasatin H (15), in which the tetrapeptide is esterified at the C-terminus by the secondary hydroxyl group of 3-phenyl-1,2-propanediol. The absolute stereochemistry of dolastatin H (14) and isodolastatin H (15) was unambiguously determined by the enantioselective total synthesis.

著者

武藤 毅 近藤 隆史 柴田 拓伸 曽根 大紀 藤田 達也 桐生 稔 木越 英夫 小鹿 一 山田 靜之

出版者

天然有機化合物討論会実行委員会

雑誌

天然有機化合物討論会講演要旨集

巻号頁・発行日

vol.37, pp.230-235, 1995

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Constituents of the Japanese sea hare Dolabella auricularia collected in Mie Prefecture, Japan were examined by using bioassay, and new cytotoxic depsipeptides, dolastatins G (1) and H (14) and isodolastatin H (15) were isolated. Dolastatin G (1) showed cytotoxicity against HeLa-S_3 cells with an IC_<50> of 1.0μg/mL. On the basis of 2D NMR technique, dolastatin G (1) has proved to be a 35-membered cyclic depsipeptide which consists of a hexapeptide and two new hydroxy acids. The absolute stereochemistry of the hexapeptide moiety was determined by the chiral HPLC analysis of amino acids obtained by acidic hydrolysis of dolastatin G (1). The absolute stereochemistry of two hydroxy acid parts was determined by the enantioselective synthesis of two corresponding fragments obtained by degradation of dolastatin G (1). For the purpose of confirming the stereostructure of dolastatin G (1), synthetic studies on dolastatin G (1) have been carried out. Three subunits, 7, 10, and 11, were synthesized, coupling of which gave seco acid 13. The synthesis of dolastatin G (1) from seco acid 13 is in progress. A 1:1 mixture of dolastatin H (14) and isodolastatin H (15) showed potent cytotoxicity against HeLa-S_3 cells with an IC_<50> of 0.00381μg/mL. On the basis of spectroscopic data, dolastatin H (14) has proved to be a linear tetrapeptide which contains two unusual amino acids and is esterified at the C-terminus by the primary hydroxyl group of 3-phenyl-1,2-propanediol. Isodolastatin H (15) is the structural isomer of dolasatin H (15), in which the tetrapeptide is esterified at the C-terminus by the secondary hydroxyl group of 3-phenyl-1,2-propanediol. The absolute stereochemistry of dolastatin H (14) and isodolastatin H (15) was unambiguously determined by the enantioselective total synthesis.

著者

林 恭子 濱田 康正 塩入 孝之

出版者

天然有機化合物討論会実行委員会

雑誌

天然有機化合物討論会講演要旨集

巻号頁・発行日

vol.33, pp.109-115, 1991

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Dolastatin 10, a potent antineoplastic substance, was isolated from an Indian Ocean sea hare, Dolabella auricularia. The absolute stereostructure of dolastatin 10, four constituents of which are unusual amino acids, was unambiguously determined by its total synthesis to be 1. Since the reported synthesis lacks stereo-selectivity, we have developed a more efficient route to dolastatin 10, a medicinally interesting peptide. Z-(S)-Dolaphenine was prepared by the Hantzsch method using Z-L-Phe-NH_2 as a starting material. (2R, 3R, 4S)-Dolaproine was prepared from Boc-(S)-prolinal (5) and N-propionyloxazolidinone 4 by the Evans aldol methodology. The unexpected threo aldol adduct 7 was produced as the major product with a small amount of the expected erythro adduct 6 when di-n-butylboron triflate was used in excess (Table 1). Stereochemistries of these aldol adducts were determined on the basis of ^1H-NMR analyses of their corresponding cyclic derivatives 18. Further investigation about this reversal of selectivity was carried out with a variety of aldehydes including amino aldehydes under the above reaction conditions (Table 2). (3R, 4S, 5S)-Dolaisoleuine, an isostatine analogue, was prepared from Boc-L-isoleucine via the β-ketoester 22, and (S)-dolavaline was prepared from L-valine according to the literature. Assembling each constituent obtained above was efficiently carried out in a stepwise manner from the C-terminal. DEPC was mainly used for the coupling, and the attachment of Boc-L-valine with the tripeptide fragment was accomplished by use of Bop-Cl. Dolastatin 10 (1) thus synthesized was identical with the natural one in every respect.

著者

林 恭子 濱田 康正 塩入 孝之

出版者

天然有機化合物討論会実行委員会

雑誌

天然有機化合物討論会講演要旨集

巻号頁・発行日

vol.33, pp.109-115, 1991

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Dolastatin 10, a potent antineoplastic substance, was isolated from an Indian Ocean sea hare, Dolabella auricularia. The absolute stereostructure of dolastatin 10, four constituents of which are unusual amino acids, was unambiguously determined by its total synthesis to be 1. Since the reported synthesis lacks stereo-selectivity, we have developed a more efficient route to dolastatin 10, a medicinally interesting peptide. Z-(S)-Dolaphenine was prepared by the Hantzsch method using Z-L-Phe-NH_2 as a starting material. (2R, 3R, 4S)-Dolaproine was prepared from Boc-(S)-prolinal (5) and N-propionyloxazolidinone 4 by the Evans aldol methodology. The unexpected threo aldol adduct 7 was produced as the major product with a small amount of the expected erythro adduct 6 when di-n-butylboron triflate was used in excess (Table 1). Stereochemistries of these aldol adducts were determined on the basis of ^1H-NMR analyses of their corresponding cyclic derivatives 18. Further investigation about this reversal of selectivity was carried out with a variety of aldehydes including amino aldehydes under the above reaction conditions (Table 2). (3R, 4S, 5S)-Dolaisoleuine, an isostatine analogue, was prepared from Boc-L-isoleucine via the β-ketoester 22, and (S)-dolavaline was prepared from L-valine according to the literature. Assembling each constituent obtained above was efficiently carried out in a stepwise manner from the C-terminal. DEPC was mainly used for the coupling, and the attachment of Boc-L-valine with the tripeptide fragment was accomplished by use of Bop-Cl. Dolastatin 10 (1) thus synthesized was identical with the natural one in every respect.

著者

藤田 智子

出版者

オーストラリア学会

雑誌

オーストラリア研究 (ISSN:09198911)

巻号頁・発行日

vol.22, pp.129-131, 2009-03-20 (Released:2017-05-10)