- 著者
-
田代 実
西岡 清
- 出版者
- Meeting of Osaka Dermatological Association
- 雑誌
- 皮膚 (ISSN:00181390)
- 巻号頁・発行日
- vol.12, no.1, pp.12-14, 1970 (Released:2010-08-25)
- 参考文献数
- 7
1-Chloroacetophenone, active ingradient in a tear-gas, CN, widely used by police authorities in Japan, was found to produce allergic contact dermatitis in exposed demonstrators in high incidence. Of 48 students in a barricade, shot with 1-chloroacetophenone, 37 suffered from acute contact dermatitis varing from erythema to severe bulla. In 15 cases, spontaneous flare-up phenomenon was observed 7 to 14 days after exposure. The results of patch test examinations in man and guinea pigs indicated that 1-chloroacetophenone is a potent sensitizer and a strong primary irritant.