著者
Paulo Gentil Elke Oliveira Martim Bottaro
出版者
Japan Society of Physiological Anthropology
雑誌
Journal of PHYSIOLOGICAL ANTHROPOLOGY (ISSN:18806791)
巻号頁・発行日
vol.25, no.5, pp.339-344, 2006 (Released:2006-10-01)
参考文献数
38
被引用文献数
27 47

Mechanical stimuli have often been suggested to be the major determinant of resistance training adaptations; however, some studies suggested that metabolic changes also play an important role in the gains of muscle size and strength. Several resistance training methods (RTM) have been employed with the purpose of manipulating mechanical and metabolic stimuli; however, information about their physiological effects are scarce. The objective of this study was to compare the time under tension (TUT) and blood lactate responses among four different RTM reported in the literature. The four RTM were performed in a knee extension machine at 10 repetition maximum (RM) load by 12 recreationally trained young men. The RTM tested were: 10RM, super-slow (SL—subjects performed one 60-second repetition with 30 seconds for eccentric and 30 seconds for concentric phase), functional isometrics (FI—in each repetition, a five-second maximal isometric contraction was executed with the knees fully extended) and adapted vascular occlusion (VO—subjects performed a 20-second maximal isometric contraction with the knees fully extended and immediately proceeded to normal isoinertial lifts). According to the results, all RTM produced significant increases in blood lactate levels. However, blood lactate responses during FI (4.48±1.57 mM) and VO (4.23±1.66 mM) methods were higher than the SL method (3.41±1.14 mM). The TUT for SL (60 s), FI (56.33±6.46 s), and VO (53.08±4.76 s) methods were higher than TUT for 10RM (42.08±3.18 s). Additionally, TUT for the SL method was higher than TUT during the VO method. Therefore, the SL method may not be recommended if one wants to provide a high metabolic stimulus. The FI method appeared to be especially effective in promoting both type of stimuli.
著者
大久保 英哲
出版者
一般社団法人 日本体育学会
雑誌
体育学研究 (ISSN:04846710)
巻号頁・発行日
pp.12047, (Released:2013-01-16)
参考文献数
37
被引用文献数
2

It is said that the history of Association Football in Japan, especially student soccer, began when an Englishman named DeHavilland moved from the Fourth High School in Kanazawa to the Tokyo Higher Normal School in September 1904, where he started coaching soccer. It has been recorded in the history of the Tokyo Higher Normal School soccer club that “some students of the University in Tokyo who said they had been taught football in Kanazawa came to Otsuka with their teacher, and we played a practice match together in December, 1904”. This article suggests that DeHavilland had also taught soccer in Kanazawa. However, in the history of the Fourth High School soccer club, it is stated that “soccer began in Kanazawa in 1924”, and does not mention DeHavilland. On the basis of this evidence, the history of soccer in Japan states that “this may have not been the case, because of the short stay of DeHavilland and lack of any proof that soccer was played in Kanazawa”. Accordingly, the purpose of the present study was to obtain documentary evidence of DeHavilland and to clarify whether he did, in fact, play soccer in Kanazawa during 1898-1904, based on new documents from the Fourth High School and articles in the school union magazine at that time. The findings obtained were as follows: 1.  DeHavilland urged students to play football after he started working at the Fourth High School in 1898. His words at the kick-off, which marked the start of student soccer in Japan, were: “ It is no matter, hailing, snowing, raining. Come and play!” 2.  It is stated in Hokushinkai magazine that DeHavilland was involved in establishing a football club in 1898. Mention of the football club appeared in the Fourth High School Union rulebook in 1899, and the name DeHavilland appeared in the list of board members of the football club in 1901. 3.  On April 18th, 1901, football was played for 30 minutes at the Fourth High School as one of the sports at the sports festival. 4.  On October 5th, 1902, at the ceremony to mark the opening of the “football club” at Ishikawa Prefectural Second Junior High School, DeHavilland and Wohlfarth both played goalkeeper. This evidence of the involvement of DeHavilland and Wohlfarth in soccer at the Fourth High School and in Kanazawa should be regarded as one of the hidden roots of student soccer in Japan.
著者
Noriaki Kawano Koji Ichinose Yutaka Ebizuka
出版者
The Pharmaceutical Society of Japan
雑誌
Biological and Pharmaceutical Bulletin (ISSN:09186158)
巻号頁・発行日
vol.25, no.4, pp.477-482, 2002 (Released:2002-07-10)
参考文献数
37
被引用文献数
30 40

Costus speciosus produces a large quantity of steroidal glycosides derived from the sole aglycone, diosgenin. Cycloartenol, a product of oxidosqualene cyclase (OSC), is postulated to be a common intermediate for phytosterols of primary metabolism and diosgenin of secondary metabolism, possibly providing a metabolic branch point. Two cDNAs, CSOSC1 and CSOSC2, were cloned from C. speciosus by RT-PCR and cDNA library screening. Both cDNAs encode 759 amino acids with high mutual identity (74%), resembling (>55% identity) the known OSCs. Phylogenetic tree analysis indicated that the gene products occupy distinct positions from those of cycloartenol synthases (CASs) and triterpene synthases from dicotyledonous plants. By functional expression in yeast, CSOSC1 and CSOSC2 were proved to encode a CAS and a multifunctional triterpene synthase, respectively. The present result is the first demonstration of the functional expression of OSCs from monocotyledonous plants.
著者
緒方 潤 花尻(木倉) 瑠理 吉松 嘉代 木内 文之 合田 幸広
出版者
公益社団法人 日本薬学会
雑誌
YAKUGAKU ZASSHI (ISSN:00316903)
巻号頁・発行日
vol.128, no.11, pp.1707-1711, 2008-11-01 (Released:2008-11-01)
参考文献数
11
被引用文献数
4 10

Cannabis plants show a high Δ9-tetrahydrocannabinol content and are used as a psychoactive drug. Therefore the cultivation of hemp and its possession are prohibited by law in Japan. Meanwhile, Cannabis seeds have been used as a component of shichimi-togarashi (a Japanese spice), bird feed, or a crude drug (mashinin). To exclude the possibility of germination, it is officially noticed that hemp seeds must be killed. However, the number of violators has increased in recent years. To judge the ability of seed germination, a germination test is performed. However, the test requires several days and thus has not been used for on-site inspection. In this study, we developed a rapid detection method to determine the ability of Cannabis seeds to germinate using 2,3,5-triphenyl-2H-tetrazolium chloride (TTC). The principle of the assay is as follows. The endogenous respiratory enzymes in hemp seeds convert added colorless TTC into red 1,3,5-triphenylformazan. Consequently, a living embryo is stained red, while red does not appear in the dead seeds. The reaction was active over a pH range of 8.0-9.0, and the optimum activity was found from 40 to 50°C. Under the optimum conditions, we were able to determine the ability of seeds to germinate based on the presence of color within 20 min. Since this method is rapid and simple, it is applicable to on-site inspections. In addition, it could be used as an alternative technique to the germination test, because erroneous decisions is cannot occur under the assay principle.
著者
Takayuki Yoshinaga Satoshi Ikeda Masahiro Shikuwa Yoshiyuki Miyahara Shigeru Kohno
出版者
The Japanese Circulation Society
雑誌
Circulation Journal (ISSN:13469843)
巻号頁・発行日
vol.67, no.3, pp.229-232, 2003 (Released:2003-02-25)
参考文献数
25
被引用文献数
17 23

Pulmonary thromboembolism (PTE) is associated with various electrocardiogram (ECG) abnormalities, but the utility of evaluating the severity of PTE based on ECG abnormalities alone has not been investigated in Japanese patients previously. The purpose of this study was to examine the relationship between ECG abnormalities and the mean pulmonary artery pressure (MPAP) in patients with acute massive PTE (AMPTE). ECG examination of 21 patients, who were diagnosed with AMPTE by pulmonary arteriography, found that S1Q3T 3 was the most frequently observed abnormality (in 67% of the patients), followed by negative T (62%), clockwise rotation (57%), and ST elevation (48%). When these patients were divided into 2 groups based on the level of MPAP, 8 of the 11 ECG findings, which were associated with PTE in a previous report, were more frequently observed in Group H (MPAP ≥40 mmHg) than in Group L (MPAP <40 mmHg). MPAP correlated significantly with the total number of ECG abnormalities (r=0.82, p<0.001). In particular, at least 5 ECG abnormalities were noted in patients with MPAP ≥45 mmHg. These results suggested that the total number of ECG abnormalities in patients with AMPTE can be used to evaluate the severity of APTE, including PAP level. (Circ J 2003; 67: 229 - 232)
著者
Masami Kosuge Kazuo Kimura Toshiyuki Ishikawa Toshiaki Ebina Kiyoshi Hibi Kengo Tsukahara Masahiko Kanna Noriaki Iwahashi Jyun Okuda Naoki Nozawa Hiroyuki Ozaki Hideto Yano Tatuya Nakati Ikuyoshi Kusama Satoshi Umemura
出版者
The Japanese Circulation Society
雑誌
Circulation Journal (ISSN:13469843)
巻号頁・発行日
vol.70, no.6, pp.750-755, 2006 (Released:2006-05-25)
参考文献数
27
被引用文献数
31 35

Background The significance of inverted T waves remains unclear in patients with acute pulmonary embolism (PE). Methods and Results The relationship of the number of leads with inverted T waves to the severity of PE in 40 patients with acute PE was studied. Patients were classified into 3 groups according to the number of leads with inverted T waves on the admission electrocardiogram (ECG): 15 patients, ≤3 leads (group L); 12 patients, 4-6 leads (group M); and 13 patients, ≥7 leads (group H). In groups L, M and H, the rates of right ventricular dysfunction on echocardiography were 47%, 92% and 100% (p<0.01), respectively, and the rates of in-hospital complicated events (including death or the need for catecholamine support, cardiopulmonary resuscitation or mechanical cardiovascular support because of hemodynamic instability) were 0%, 8% and 46% (p=0.004), respectively. On multivariate analysis, arterial hypotension at presentation (odds ratio (OR) 8.96, p=0.049) and inverted T waves in ≥7 leads on the admission ECG (OR 16.8, p=0.037) were the only independent predictors of in-hospital complicated events. Conclusions The number of leads with inverted T waves may be a useful and simple marker of increased risk for early complications in patients with acute PE. (Circ J 2006; 70: 750 - 755)
著者
萩尾 友宣 柴田 陽三 篠田 毅 伊崎 輝晶
出版者
日本肩関節学会
雑誌
肩関節 (ISSN:09104461)
巻号頁・発行日
vol.35, no.3, pp.837-840, 2011 (Released:2011-12-21)
参考文献数
9

Proprioception was studied in rotator cuff tear and normal shoulder using active angle reproduction test. Subjects and methods: In cuff tear group(RCT), 33 cases (33 shoulders) were studied. They were 19 males and 14 females, their average age was 66.4 years.The average active elevation angle was 112.4° and the average external rotation angle was 51.4°. As a control group (C), 20 cases (20 shoulders) who had not had previous injury or disease in their shoulder were studied. Average elevation angle was 160.3° and average external rotation angle was 61.9°. The subjects were studied sitting on a chair and had a bandage put over their eyes. They rotate or elevate their shoulder to any angle. The difference absolute values between average of 3 times of reproduction of the angle and the target angle were studied. The target angles were 30° of internal rotation, 30° and 45° external rotation, 30°, 45° and 60° of elevation. In 30° of IR, error angle revealed 7.0° in RCT and 2.6° in C group (P<0.01). These were 4.6° and 2.5°(P<0.01) in 30° of ER, 3.6° and 2.5°(P=0.15) in 45° of ER. These were 4.0° and 2.1° in 30° of elevation (P<0.05), 4.1° and 1.9° in 45° of elevation (P<0.01), 4.8° and 2.4° in 60° of elevation(P<0.01). Proprioception of rotator cuff tear was lower than that of normal shoulder.
著者
Takashi Kitano Norimasa Matsuoka Naruya Saitou
出版者
The Genetics Society of Japan
雑誌
Genes & Genetic Systems (ISSN:13417568)
巻号頁・発行日
vol.72, no.1, pp.25-34, 1997 (Released:2002-11-26)
参考文献数
30
被引用文献数
13 16

The phylogenetic relationship among the salmonid fishes of the genus Oncorhynchus has been analyzed using various kinds of markers for a long time. However, there are three major disagreements among those studies; (1) the authenticity of the Pacific salmon group as a monophyletic cluster, (2) the phylogenetic relationship among three Pacific salmons (pink salmon, sockeye salmon, and chum salmon), and (3) the phylogenetic position of masu salmon. We used allozyme electrophoresis to clarify the phylogenetic relationship between the Pacific salmon group and the Pacific trout group. Furthermore, we reanalysed published mitochondrial DNA D-loop sequences (Shedlock et al., 1992). Allozymic data and mtDNA data indicated the following consistent results; (1) all Pacific salmons formed a monophyletic cluster, (2) chum salmon and pink salmon were clustered within those Pacific salmons, (3) masu salmon formed a cluster with other Pacific salmons and diverged first in this group.
著者
Shujun Zhou Junzheng Wang Ayae Sugawara-Narutaki Atsushi Shimojima Tatsuya Okubo
出版者
The Chemical Society of Japan
雑誌
Chemistry Letters (ISSN:03667022)
巻号頁・発行日
vol.42, no.5, pp.481-482, 2013-05-05 (Released:2013-05-05)
参考文献数
10
被引用文献数
4

Silica nanospheres (SNSs) synthesized with different base catalysts assemble into one-dimensional (1D) chain-like nanostructures at proper pH levels in the presence of the block copolymer F127. The addition of basic amino acids or the removal of base catalysts by dialysis influences the pH of 1D assembly. The base molecules affect assembly by modifying the electrostatic repulsion among the SNSs; however, they are not indispensable for this 1D assembly phenomenon.
著者
遠藤 貢 成高 義彦 五十畑 則之 浅香 晋一 山口 健太郎 村山 実 勝部 隆男 小川 健治 布田 伸一 大塚 邦明
出版者
日本外科系連合学会
雑誌
日本外科系連合学会誌 (ISSN:03857883)
巻号頁・発行日
vol.34, no.6, pp.1066-1070, 2009 (Released:2010-12-30)
参考文献数
14
被引用文献数
1 1

今回われわれは,心臓移植14年後に発症した悪性リンパ腫による腸閉塞の1例を経験したので報告する. 症例は37歳の男性.23歳時に拡張型心筋症で心臓移植の既往がある.2008年2月より,下血で発症した悪性リンパ腫に対し化学療法を2クール施行したが,腸閉塞を発症した.イレウス管造影で空腸に高度な狭窄像を認め,外科的治療を施行した.病理組織所見では悪性リンパ腫による腸管狭窄であった.周術期は免疫抑制剤の投与量を調節しながら,厳重な術後管理により良好に経過した. 心臓移植後に消化管手術を施行した報告は少なく,周術期における免疫抑制剤の投与法や術後管理に関する知見も極めて少ない.本症例は貴重な経験と考え報告した.
著者
小林 史歩
出版者
社団法人 プラズマ・核融合学会
雑誌
プラズマ・核融合学会誌 (ISSN:09187928)
巻号頁・発行日
vol.78, no.7, pp.678-684, 2002 (Released:2005-12-08)
参考文献数
16

Gamma-raybursts (GRBs) are the most explosive events after the big bang. For a few seconds a GRB be comes the brightest object in the Universe, overshining the rest of the Universe combined. Clearly this reflects extreme conditions that are fascinating and worth exploring. GRB observations were recently revolutionised by the discovery of the delayed X-ray emission, called ”afterglow”. These observations revealed that the deceleration of relativistically expanding fireballs causes GRBs. I discuss special relativistic effects that play an important role in the fireball model.
著者
Arata Hidano Yoko Hayama Toshiyuki Tsutsui
出版者
National Institute of Infectious Diseases, Japanese Journal of Infectious Diseases Editorial Committee
雑誌
Japanese Journal of Infectious Diseases (ISSN:13446304)
巻号頁・発行日
vol.65, no.5, pp.396-402, 2012 (Released:2012-09-25)
参考文献数
23
被引用文献数
4 7

Rabies was eliminated in Japan over 50 years ago; however, the recent increase in the movement of humans and animals across the world highlights the potential threat of disease reentry into the country. The immune status against rabies among the dog population in Japan is not well known; thus, the purpose of this study was to estimate the prevalence of dogs with effective immunity from the vaccination history using a web-based survey. We found that 76.9% (95% confidence interval, 75.8–78.1) of dogs in this study population belonged to the population in which 90% were assumed to have the internationally accepted antibody titer. We showed that dogs taken less frequently for walks were less likely to be vaccinated. Additionally, the frequency of encounters with other dogs during walks and the number of individuals in households were associated with vaccination history. To our knowledge, this study is the first report estimating the prevalence of dogs in Japan with effective immunity against rabies. Further, we identified the population with low vaccination coverage as well as the heterogeneous characteristics of vaccination history among the dog population. These findings contribute to the implementation of an efficient strategy for improving the overall vaccination coverage in Japan and the development of a quantitative risk assessment of rabies.
著者
Yuki Tsuji Hiroyuki Ohno
出版者
The Chemical Society of Japan
雑誌
Chemistry Letters (ISSN:03667022)
巻号頁・発行日
vol.42, no.5, pp.527-529, 2013-05-05 (Released:2013-05-05)
参考文献数
24
被引用文献数
10

Novel azolate-type ionic liquids (ILs), alkyltributylphosphonium benzimidazolates (alkyl chain: methyl, butyl, and octyl), were prepared by neutralization of the corresponding alkyltributylphosphonium hydroxides with benzimidazole. All the azolate-type ILs prepared here showed high ionic conductivities above 10−3 S cm−1 at 80 °C, and good thermal stability over 300 °C. They are expected to be useful platforms for functional ILs having good thermal stabilities.
著者
Hiroaki Sato Yoko Ishii Hikaru Momose Takafumi Sato Kanae Teramoto
出版者
The Mass Spectrometry Society of Japan
雑誌
Mass Spectrometry (ISSN:2187137X)
巻号頁・発行日
vol.2, no.1, pp.A0014, 2013-02-01 (Released:2013-01-31)
参考文献数
22
被引用文献数
10 13

The structural characterization of copolymers by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS) remains a challenging task, since their random comonomer distribution creates very complicated mass spectra. In this study, a high-resolution TOF mass spectrometer with a spiral ion trajectory was applied to the structural and compositional characterization of free radical copolymerized poly(methyl methacrylate-co-tert-butyl methacrylate), poly(MMA-co-tBMA)s in ethyl lactate acting as a chain transfer agent. Virtually complete peak assignments of the isobaric components within the poly(MMA-co-tBMA)s served to identify the end-group combinations and copolymer compositions of individual copolymer components, allowing the distributions of comonomer compositions and six types of end-group combinations to be evaluated.