著者
Ying-Wu Lin Chang-Ming Nie Li-Fu Liao
出版者
The Chemical Society of Japan
雑誌
Chemistry Letters (ISSN:03667022)
巻号頁・発行日
vol.40, no.12, pp.1330-1331, 2011-12-05 (Released:2011-11-09)
参考文献数
27
被引用文献数
4

Uranium is toxic to the human body with mechanisms not fully understood. The interaction between uranyl ion (UO22+) and ubiquitin (Ub) was predicted by molecular modeling, molecular dynamics (MD) simulation, and steered molecular dynamics (SMD) simulation. The structural and dynamics consequences, as well as protein unfolding behavior, upon uranyl binding to two surface residues of Ub, Glu18 and Asp21, were revealed at an atomic level. This in silico study exhibits a possibility of UO22+ binding to Ub, providing a possible mechanism of uranyl toxicity in vivo.
著者
Isao YAMAMOTO Hironobu FUJIWARA Masashi KAMOGAWA Atsushi IYONO Valeri KROUMOV Takashi AZAKAMI
出版者
日本学士院
雑誌
Proceedings of the Japan Academy, Series B (ISSN:03862208)
巻号頁・発行日
vol.85, no.10, pp.485-490, 2009 (Released:2009-12-14)
参考文献数
7
被引用文献数
2 2

Temporal correlation between atmospheric anomalies and earthquakes has recently been verified statistically through measuring VHF FM radio waves transmitted beyond the line-of-sight. In order to locate the sources of such atmospheric anomalies, we developed a VHF interferometer system (bistatic-radar type) capable of finding the arrival direction of FM radio waves scattered possibly by earthquake-related atmospheric anomalies. In general, frequency modulation of FM radio waves produces ambiguity of arrival direction. However, our system, employing high-sampling rates of the order of kHz, can precisely measure the arrival direction of FM radio waves by stacking received signals.(Communicated by Seiya UYEDA, M.J.A.)
著者
石田 淳
出版者
数理社会学会
雑誌
理論と方法 (ISSN:09131442)
巻号頁・発行日
vol.18, no.2, pp.211-228, 2003-09-30 (Released:2009-01-20)
参考文献数
13
被引用文献数
5

階層イメージならびに階層帰属意識にかんするFKモデルは,「中」意識肥大現象などの人々の階層イメージ,階層帰属意識の傾向性を見事に説明している.しかしながら,FKモデルは同一客観階層内での階層帰属意識のばらつきをうまく説明することができない.本稿は,FKモデルに新たな公理を加えた修正モデルを提唱する.新たな公理は,スキャニング・プロセスの打ち切り条件を定めるものであり,行為者の階層イメージ形成過程において,他者の階層的地位の認識にかかるコストを軽減するための「認識の効率性」を仮定したものである.この修正モデルによって,同一客観階層内での階層帰属意識のばらつきが表現されるとともに,経験的データとの適合性も改善される.また,認識の効率化によって生じる意図せざる結果としての「格上げバイアス傾向」が生じる条件も修正モデルによって明らかになる.
著者
高木 昌興
出版者
日本鳥学会
雑誌
日本鳥学会誌 (ISSN:0913400X)
巻号頁・発行日
vol.58, no.1, pp.1-17, 2009-05-01 (Released:2009-05-20)
参考文献数
72
被引用文献数
6 8

The characteristics of the avifauna of the Nansei Shoto are explained. The Nansei Shoto consists of the Ryukyu, Senkaku, and Daito islands. The avifauna of the islands, in particular in relation to the species endemic to the islands and those species also occurrign in the islands as well as in both Kyushu and Taiwan, was investigated by means of the literature, mainly the “Check-List of Japanese birds. Sixth Revised Edition (The Ornithological Society of Japan 2000)”. The number of breeding bird species on islands was greatest on the largest islands, and reached maxima (37 species) on both Okinawa and Iriomote islands. In order to understand the similarities between the avifaunas of the various islands, Nomura-Simpsons' coefficient of breeding birds on twelve representative islands of the Nansei Shoto, Kyushu, and Taiwan were calculated. The results of the cluster analyses of the similarities among islands were partly explained by the distances between islands. It is inferred that disparities between the similarities of avifaunas and distances among islands result from differences in the environments of each island.
著者
Keisuke Suzuki Katherine A Simpson James S Minnion Joyceline C Shillito Stephen R Bloom
出版者
The Japan Endocrine Society
雑誌
Endocrine Journal (ISSN:09188959)
巻号頁・発行日
pp.1003230405, (Released:2010-04-14)
被引用文献数
137 210

The World Health Organisation has estimated that by 2015 approximately 2.3 billion adults will be overweight and more than 700 million obese. Obesity is associated with an increased risk of diabetes, cardiovascular events, stroke and cancer. The hypothalamus is a crucial region for integrating signals from central and peripheral pathways and plays a major role in appetite regulation. In addition, there are reciprocal connections with the brainstem and higher cortical centres. In the arcuate nucleus of the hypothalamus, there are two major neuronal populations which stimulate or inhibit food intake and influence energy homeostasis. Within the brainstem, the dorsal vagal complex plays a role in the interpretation and relaying of peripheral signals. Gut hormones act peripherally to modulate digestion and absorption of nutrients. However, they also act as neurotransmitters within the central nervous system to control food intake. Peptide YY, pancreatic polypeptide, glucagon-like peptide-1 and oxyntomodulin suppress appetite, whilst ghrelin increases appetite through afferent vagal fibres to the caudal brainstem or directly to the hypothalamus. A better understanding of the role of these gut hormones may offer the opportunity to develop successful treatments for obesity. Here we review the current understanding of the role of gut hormones and the hypothalamus on food intake and body weight control.
著者
本田 真也
出版者
一般社団法人 日本生物物理学会
雑誌
生物物理 (ISSN:05824052)
巻号頁・発行日
vol.49, no.3, pp.126-129, 2009 (Released:2009-05-25)
参考文献数
16

On the ideology of minimalism, we have designed a micro-protein consisting of only 10 amino acids. The molecule, CLN025, exhibits a β-hairpin structure in both crystalline state and aqueous solution. Thermal unfolding is shown to be reversible and can be fitted as a two-state transition. Molecular dynamics simulation starting from an extended conformation leads to a funnel-shaped surface and scale-free network, being the structures located at the bottom and the hub similar to the experimental ones. Considering these consequences, we proposed the concept of “ideal protein” as a way to clarify the differences between “protein” and “peptide”.
著者
竹中 晃二 大場 ゆかり 満石 寿
出版者
一般社団法人 日本体育・スポーツ・健康学会
雑誌
体育学研究 (ISSN:04846710)
巻号頁・発行日
vol.55, no.1, pp.157-168, 2010 (Released:2010-07-20)
参考文献数
17
被引用文献数
1

The Relapse Prevention Model (RPM) has provided a framework for successful long-term maintenance of some types of health behavior. The purpose of this study was to identify high-risk situations for inducing exercise slip and lapse, which may lead to real relapse, and to clarify the coping strategies in this regard for Japanese regular exercisers, from the viewpoint of the RPM. We examined 677 regular exercisers by obtaining open-ended responses about 1) their typical high-risk situations as immediate determinants interfering with their planned exercise, 2) their coping responses to those situations, and 3) subsequent patterns of exercise outcome. High-risk situations included fatigue, bad weather, bad conditioning or injury, work or academic obligation, troubles in personal life, interpersonal relationships, and getting into a groove, although the frequency orders differed according to gender. Females were more aware that interpersonal relationships were associated with a higher incidence of exercise slip and lapse than did males, whereas males identified fatigue as the highest risk. Positive coping strategies as problem solving and behavior strategies as execution of routine work were most commonly employed, and were associated with positive exercise outcome for both females and males. On the other hand, the usage of negative coping strategies tended to lead to slip and lapse. These results suggest that adoption of coping strategies regarding high-risk situations is associated with exercise outcome, although the effects differ between males and females. These data demonstrate the importance of coping ability or strategy for exercise and suggest that slip and lapse may result from ineffective coping with high-risk situations. These findings confirm and extend previous work on the application of the RPM for examining exercise slip and lapse. Measurement issues and knowledge derived from this study are discussed in relation to future application to real practice.
著者
荒牧 草平
出版者
数理社会学会
雑誌
理論と方法 (ISSN:09131442)
巻号頁・発行日
vol.22, no.2, pp.189-203, 2007-10-31 (Released:2008-01-08)
参考文献数
25
被引用文献数
3

本稿ではRobert D. Mareが提案し、教育達成過程の実証分析で国際的に事実上のスタンダードとなってきた、通称Mareモデルとその応用モデルによる分析(Transitions Approach)を通して、わが国の教育達成過程における不平等とその変動を実証的に明らかにするとともに、不平等生成に関する理論の目指すべき方向性について検討した。分析の結果、先行研究において繰り返し確認された階層効果逓減現象が、わが国の場合は戦前の一定期間にのみ認められること、中等教育機会の平等化と高等教育機会の不平等化の同時進行は、戦後の高学歴化期ではなく戦前における中等教育のマス化に関わって生じたこと、中等教育であれ高等教育であれ格差の拡大は上位層による希少財の先取りと関わって生じた可能性のあること、MMI仮説の主張する上位層の飽和による平等化がわが国の場合には必ずしも認められるわけではないこと等が明らかとなった。
著者
山田 昌弘
出版者
日本家族社会学会
雑誌
家族社会学研究 (ISSN:0916328X)
巻号頁・発行日
vol.21, no.1, pp.17-20, 2009-04-30 (Released:2010-04-30)
参考文献数
11

2008年度の家族社会学会のシンポジウムでは,貧困を伴った家族の経済格差拡大という社会における子育て状況を解明するために,子育てする親の調査を精力的になされている3人の研究者を報告者としてお招きした。後藤憲子氏には親の経済状況の変化と親の子育てへの態度の現状を,片岡栄美氏からは,お受験などに熱心な高階層の親の子育て戦略と意識を,湯澤直美氏から,経済的に困難な家族における子育ての実態をご報告いただいた。討論者として,竹村祥子氏,吉川徹氏にお願いし,司会は渡辺秀樹と山田昌弘が当たった。
著者
牟田 和恵
出版者
日本家族社会学会
雑誌
家族社会学研究 (ISSN:0916328X)
巻号頁・発行日
vol.20, no.1, pp.7-9, 2008-04-30 (Released:2009-08-07)
被引用文献数
1 1

シンポジウムでは,1対1の性的関係に絶対的基盤をおかないつながり,あるいはそれを基としながらも,カップルの対の関係(とその子ども)という核家族的関係に閉じないつながりによる,「家族のオルタナティブ」の新たな可能性を検討した。小谷部育子は「コレクティブハウジングの理念と実践」,釜野さおりは「レズビアン家族とゲイ家族から『従来の家族』を問う」,上野千鶴子は「家族の臨界:ケアの再分配問題をめぐって」と題して,新たな親密さ・拠るべき生の基盤の構築の可能性を,実践的・理論的に提示した。討論者の野沢慎司は,ステップファミリー研究の知見を生かし,これまでの家族研究とのつながりを論じた。司会は,牟田和恵と須長史生が務めた。
著者
近藤 信太郎 金澤 英作 中山 光子
出版者
一般社団法人 日本人類学会
雑誌
Anthropological Science (Japanese Series) (ISSN:13443992)
巻号頁・発行日
vol.114, no.1, pp.63-73, 2006 (Released:2006-06-23)
参考文献数
78

ヒトの上顎大臼歯と第二乳臼歯に見られるカラベリー結節は最もよく知られた歯冠形質のひとつである。この形質に関しては様々な観点から多数の研究が行われてきた。本稿では最近の研究を紹介するとともに,この形質が歯の人類学に与えた多くの課題を3つのキーワード「分布」,「遺伝」,「系統と発生」にしたがって検証した。「分布」の項では形質の基準,集団間の違い,ヨーロッパ人にカラベリー結節が多く見られる理由を検討した。「遺伝」の項ではカラベリー結節の遺伝,左右側の非対称性,性染色体とカラベリー結節,性差について考察した。「系統と発生」の項ではカラベリー結節の系統発生と個体発生,カラベリー結節は大きい歯にみられるのか,に関して検討した。歯の内部構造の研究方法の開発や分子生物学的な研究によりカラベリー結節は多方面からより詳細に研究され,未解決の課題が解明されることであろう。
著者
丸山 俊明
出版者
日本建築学会
雑誌
日本建築学会計画系論文集 (ISSN:13404210)
巻号頁・発行日
vol.75, no.651, pp.1225-1230, 2010-05-30 (Released:2010-07-26)

The first Juraku-tyo was the first castle town where was built along with Jurakudai in Tensyo 14-18 (1586-90).Toyotomi government assembled the wealthy commonalty and ordered to inhabit in Juraku-tyo. The row houses were formed by intention of government and the financial power of commonalty. This paper is intended as an investigation of the row houses, which were found out in “Gosyo-sandai-Jurakudai-Gyoukou Screen”. It is clear that Toyotomi government intended to complete the row two-storied houses, which made the same eaves height.
著者
竹之下 康治
出版者
社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.24, no.3, pp.481-487, 1978-06-15 (Released:2011-07-25)
参考文献数
21
被引用文献数
1
著者
澤 裕一郎 熊澤 友子 滝本 明 馬杉 亮彦 川野 大 野村 明日香
出版者
社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.50, no.6, pp.408-411, 2004-06-20 (Released:2011-04-22)
参考文献数
12
被引用文献数
1

Paralysis of the mental nerve is one of the principal complications of surgery of the mandibular canal and mental foramen region. The position of mental foramen can be clearly depicted on CT scans. The mental foramen is bilaterally located at the mandibular premolar region and appears as a dimple on the bone surface. However, several reports have described an accessory mental foramen (AMF). We examined CT pictures taken from patients with implants for missing mandibular teeth to detect variations of the AMF. The results were follows: 1) AMFs were present in 28 patients (24.6 %). 2) Unilateral AMFs were found in 24 patients, and bilateral AMFs in 4 patients. 3) Among patients with unilateral AMFs, 21 had AMFs with one foramen, and 3 had AMFs with two foramens. Among patients with bilateral AMFs, 2 patients had one foramen on each side, and 2 had two foramens on one side. 4) The position of AMF relative to that of the mental foramen was as follows: 18 foramens were superior mesial, 8 were superior distal, 6 were inferior mesial, and 5 were inferior distal.These results suggest that one quarter of patients with missing mandibular teeth may have AMFs around the mental foramen.
著者
Masaki Yoshioka Shintaro Yokoyama Satoshi Koguchi Koichi Ikeda
出版者
Japanese Society of Human-Environment System
雑誌
人間-生活環境系学会英文誌 (ISSN:13451324)
巻号頁・発行日
vol.12, no.2, pp.73-77, 2009-12-30 (Released:2010-07-08)
参考文献数
8

We intended to clarify the present states of special old age nursing homes and elderly health care facilities in Japan especially in a cold climate region. A questionnaire survey about maintenance and control of living environment for all special old age nursing homes and elderly health care facilities in Sapporo and Fukuoka City, and Hokkaido, Saitama, Kanagawa, Osaka Prefecture and Tokyo Metropolis was performed. The main questionnaire asks about heating, air-cooling, ventilation system, sanitary system and indoor air quality including bio-aerosol and odors. We send the questionnaire sheets, which were A-4 size and four pages, to total 1,479 homes and facilities. We received total 646 answers, about 44% of total number. The 95 questionnaire items were converted 249 categories for statistical analyses.The present database for special old age nursing homes and elderly health care facilities consists of about 160,000 data. The data obtained from Sapporo City and Hokkaido Prefecture were compared with those of other regions. We show the characteristics of special old age nursing homes and elderly health care facilities in a cold climate region in this paper. The main differences were set values of air temperature in both winter and mid-summer, and air-cooling system.
著者
Taiki MIYAZAWA Kiyotaka NAKAGAWA Fumiko KIMURA Akira SATOH Teruo MIYAZAWA
出版者
Japan Society for Bioscience, Biotechnology, and Agrochemistry
雑誌
Bioscience, Biotechnology, and Biochemistry (ISSN:09168451)
巻号頁・発行日
vol.75, no.9, pp.1856-1858, 2011-09-23 (Released:2011-09-23)
参考文献数
15
被引用文献数
26

A randomized, double-blind human trial was conducted to assess the effect on the plasma carotenoid concentration of 4- or 12-week astaxanthin supplementation (1 or 3 mg/d) of 20 Japanese middle-aged and senior subjects. The plasma carotenoid concentration was significantly higher after the astaxanthin supplementation than that before in both the 1 mg/d (10 subjects) and 3 mg/d (10 subjects) groups.