著者

Shin’ichi KUDO Akemi NISHIDE Jun’ichi ISHIDA Keiko YOSHIMOTO Hiroshige FURUTA Fumiyoshi KASAGI

出版者

Japan Health Physics Society

雑誌

保健物理 (ISSN:03676110)

巻号頁・発行日

vol.55, no.1, pp.32-39, 2020-04-01 (Released:2020-05-21)

参考文献数

26

被引用文献数

2 2

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The health effects of low-dose or low-dose rate of radiation are still controversial. There is little evidence to show if radiation risk is greater than other risks, such as lifestyle or socio-economic factors, including smoking. This study aimed to directly compare radiation and smoking risk on cancer mortality by deriving both risk factors simultaneously from one cohort. The study population was Japanese nuclear workers who were engaged until the end of March, 1999. A lifestyle questionnaire was distributed in 1997 and 2003 and smoking information was obtained. Radiation dose was supplied by Radiation Dose Registration Center in Radiation Effects Association. Poisson regression was used to derive radiation excess relative risk (ERR) per 100 mSv and smoking (ERR) per 20 pack-years. Radiation doses were lagged by 10 years. There were 71,733 subjects. The total person-years was 591,000, and the number of deaths for all cancers excluding leukemia was 1,326. For all cancers excluding leukemia, the ERR of radiation per 100 mSv was 0.08 (90% CI: −0.08, 0.28), and the ERR of smoking per 20 pack-years was 0.57 (90% CI: 0.44, 0.73). In addition to all cancers excluding leukemia, stomach cancer, lung cancer, smoking-related cancers showed significantly smaller radiation ERRs than smoking ERRs. These results suggest that, even if a low-dose radiation risk existed, it was much smaller than smoking risk.

著者

Kazuo Ouchi Naoyuki Oi Mari Sato Shoji Yabuki Shin-ichi Konno

出版者

THE FUKUSHIMA SOCIETY OF MEDICAL SCIENCE

雑誌

FUKUSHIMA JOURNAL OF MEDICAL SCIENCE (ISSN:00162590)

巻号頁・発行日

vol.69, no.1, pp.67-71, 2023 (Released:2023-04-05)

参考文献数

15

被引用文献数

2

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Background: When foot necrosis occurs due to lower limb blood flow disorder caused by diabetes or peripheral arterial occlusion, many patients require lower limb amputation. The functional prognosis after lower limb amputation largely depends on whether the heel can be preserved. However, there are many reports that Chopart amputation causes varus and equinus deformity, and is functionally unfavorable. We herein report a case of Chopart amputation performed with muscle balancing. Postoperatively, the foot was not deformed and the patient was able to walk independently with a foot prosthesis. Case: A 78-year-old man presented with ischemic necrosis of his right forefoot. The range of necrosis extended to the central part of the sole, so Chopart amputation was performed. In the operation, to prevent varus and equinus deformity, the Achilles tendon was lengthened, the tibialis anterior tendon was transferred through a tunnel created in the neck of talus, and the peroneus brevis tendon was transferred through a tunnel created in the anterior part of the calcaneus. At the final follow-up 7 years after the operation, no varus or equinus deformity was observed. The patient became able to stand up and walk on his heel without a prosthesis. In addition, step motion was possible by wearing a foot prosthesis.

著者

Hiroyuki Ichida Tomohiko Kazama Shin-ichi Arimura Kinya Toriyama

出版者

Japanese Society for Plant Biotechnology

雑誌

Plant Biotechnology (ISSN:13424580)

巻号頁・発行日

vol.40, no.1, pp.109-112, 2023-03-25 (Released:2023-03-25)

参考文献数

11

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A highly contiguous mitochondrial and plastid genome sequences of a japonica rice cultivar, Taichung 65, were determined by a hybrid approach with long- and short-read sequences. The assembled mitochondrial genome was 465,453 bases in length with an overall GC content of 43.8%. It was predicted to harbor 62 protein-encoding genes, 16 kinds (33 copies) of transfer RNA, and three kinds (six copies) of ribosomal RNA genes. The mitochondrial genome structure in Taichung 65 is largely the same as that of Nipponbare, but the first ∼9.5 kb sequence in Nipponbare (DQ167400) is replaced with a ∼27 kb sequence duplicated from other parts of the mitochondrial genome. Phylogenetic and sequence polymorphism analysis indicated that Taichung 65 is classified as typical japonica. The assembled plastid genome sequence was 134,551 bases in length and completely identical to the previously reported Nipponbare sequence. These near-complete organelle genome sequences will serve as fundamental resources for investigating alloplasmic cytoplasmic male sterile lines and other organelle-controlled phenomena in rice.

著者

Shin NOMOTO

出版者

The Society for Near Eastern Studies in Japan

雑誌

Orient (ISSN:04733851)

巻号頁・発行日

vol.44, pp.19-39, 2009-03-31 (Released:2014-04-02)

参考文献数

60

被引用文献数

2 2

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The fourth/tenth (A.H./C.E.) century is one of the most crucial time to the development of Ismā‘īlī Shī‘ism not only because the Fāṭimids’ claim for the sole leadership (Imāmah) conflicts with its original belief in the advent of the messianic figure called the Qā’im, but because some thinkers adopted Greek thought, especially Neoplatonism. This article aims at contributing to elucidation of how the Ismā‘īlī thinkers made consistent their doctrine on the Qā’im with newly adopted Neoplatonism in this important century, with special reference to Abū Ḥātim al-Rāzī’s (d. ca 322/933-4) Kitāb al-Iṣlāḥ, one of the oldest extant Neoplatonist-influenced texts. The text of al-Iṣlāḥ suggests that the Qā’im will resume the full contact, which Adam had enjoyed, with the two highest hypostases of Neoplatonist cosmology, that is, the Universal Intellect and the Universal Soul. Also in his text al-Rāzī implies that the advent of the Qā’im will mark or bring the full actualization of the “spiritual forms” (al-ṣuwar al-rūḥānīyah) and “simple form” (al-ṣurah al-basīṭah) of the human soul. This is also the result of the influence of the “highest simple world,” the realm of the two highest hypostases. Thus, with the background of Greek thought, especially Neoplatonism, al-Rāzī de-politicized the role and mission of the Qā’im. This idea is shared by al-Sijistani (d. after 361/971), Neoplatonist Ismā‘īlī thinker who is nearly one generation younger than al-Rāzī. Did this shared idea of the de-politicized and “spiritualized” Qā’im function as precursor for Ḥamīd al-Dīn al-Kirmānī’s (d. after 411/1020) own vision of the Qā’im and the postponing of his advent and the ultimate eschaton? This will be an issue of our future research.

著者

Yoshito MIYATA Shin OHTA Akihiko TANAKA Kaho AKIMOTO Hiroki SATO Tomoki UNO Haruna SATO Yoshitaka UCHIDA Megumi JINNO Kuniaki HIRAI Hideki INOUE Tetsuya HONMA Mayumi YAMAMOTO Shintaro SUZUKI Hironori SAGARA

出版者

The Showa University Society

雑誌

The Showa University Journal of Medical Sciences (ISSN:09156380)

巻号頁・発行日

vol.32, no.4, pp.247-256, 2020 (Released:2021-01-28)

参考文献数

28

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Mepolizumab is a monoclonal antibody against interleukin-5 used for the treatment of severe asthma. The effect of long-term mepolizumab administration and its persistence in clinical practice is poorly understood. Thus, this study aimed to investigate the effect of long-term administration of mepolizumab in patients with severe asthma. Mepolizumab was administered to 20 patients with severe asthma. We then prospectively followed the patients for 104 weeks to investigate the efficacy of long-term mepolizumab administration in clinical practice. Eleven patients were evaluated for 104 weeks. Mepolizumab administration reduced asthma exacerbations in a year from 52 to 104 weeks and improved asthma control in every period as assessed by questionnaires. Also, blood eosinophil counts decreased at every point, and blood basophil counts decreased at 104 weeks. We compared various parameters among the 11 patients who continued administration for more than 104 weeks and 7 patients who discontinued treatment due to ineffectiveness. Significant differences were observed in disease duration, maximum expiratory flow at 50%, and blood basophil count. Long-term mepolizumab administration improved asthma symptoms in patients with severe asthma and reduced the frequency of exacerbations.

著者

前島 信也 Shin'ya Maejima

出版者

国際仏教学大学院大学

雑誌

国際仏教学大学院大学研究紀要 = Journal of the International College for Postgraduate Buddhist Studies (ISSN:13434128)

巻号頁・発行日

no.22, pp.71-101, 2018-03-31

著者

Hiroaki Shiraishi Kazuhisa Ikemoto Shin Tada Yasuhiro Udagawa Masatsugu Ohtsuki Chiho Sumi-Ichinose Kazunao Kondo Takahide Nomura

出版者

Japan Atherosclerosis Society

雑誌

Journal of Atherosclerosis and Thrombosis (ISSN:13403478)

巻号頁・発行日

vol.18, no.4, pp.312-317, 2011 (Released:2011-04-27)

参考文献数

25

被引用文献数

5 5

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Aims: Cilostazol, a type III phosphodiesterase inhibitor, is utilized for the treatment of intermittent claudication and is considered to have the beneficial effects against the atherogenic process. In the present study, we examined the effects of cilostazol on BH4 biosynthesis in HUVEC treated with a mixture of the pro-inflammatory cytokines IFN-γ and TNF-α.Methods: Isolated HUVECs were grown to confluence and treated with IFN-γ (300 units/mL) and TNF-α (300 units/mL) for 16 h in order to stimulate BH4 biosynthesis. The BH4 levels were mea-sured by HPLC. The mRNA expression of GTP cyclohydrolase I (GTPCH), the rate-limiting enzyme of BH4 biosynthesis, and GTPCH feedback regulatory protein (GFRP) were quantified by real-time PCR. The GTPCH protein expression was assessed by western blot analysis.Results: Cilostazol significantly reduced the BH4 levels in cytokine-stimulated HUVEC. Cilostazol produced a concomitant increase in the cAMP levels in HUVEC. Cilostazol decreased the GTPCH activity as well as the expression of GTPCH mRNA and protein. 8-bromo-cAMP (8Br-cAMP), a cell-permeable cAMP analogue, did not reproduce the effects of cilostazol. Cilostazol did not affect the cytokine-induced inhibition of GFRP mRNA expression.Conclusions: We conclude that cilostazol inhibited cytokine-stimulated BH4 biosynthesis via a cAMP-independent mechanism in HUVEC. Our data indicate that cilostazol reduced GTPCH activity and did so by suppressing the GTPCH protein levels.

著者

SHIGEAKI AOYAGI SATORU TOBINAGA KUMIKO WADA SHIN-ICHI NATA HIROSHI YASUNAGA

出版者

Kurume University School of Medicine

雑誌

The Kurume Medical Journal (ISSN:00235679)

巻号頁・発行日

pp.MS681002, (Released:2023-02-08)

参考文献数

9

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Summary: Myocardial contusion is the most common cardiac injury from blunt chest trauma (BCT), whereas isolated valve injury is uncommon. We report a case of acute mitral regurgitation (MR) due to isolated valve injury after BCT. A 60-year-old man received an impact on his left chest by a car wheel three weeks prior to visiting our hospital. At the time a diagnosis of contusion of the chest wall without rib and sternal fractures was made. Thereafter, the patient had progressive worsening of heart failure symptoms. Eventually he developed dyspnea on slight exertion but echocardiographic evaluation was not performed at the time of diagnosis or during the three weeks prior to admission. At admission a holosystolic murmur was heard. Transthoracic echocardiography revealed prolapse of the posterior mitral leaflet due to torn chordae tendineae with severe MR and normal left ventricular wall motion. At surgery, torn chordae tendineae and a leaflet tear of the posterior leaflet were detected, and mitral valve repair was achieved without residual MR. Pathological examination of the torn chordae showed no findings of endocarditis or myxomatous degeneration. Echocardiography may play an important role for accurate and prompt diagnosis of cardiac lesions in patients with recent or a history of high-energy BCT.

著者

Daji NOH Hyunjoon SHIN Hyemin NA Sang-Kwon LEE Sooyoung CHOI Kija LEE

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.85, no.2, pp.163-166, 2023 (Released:2023-02-01)

参考文献数

26

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This study aimed to prospectively assess nasopharyngeal luminal changes in brachycephalic dogs without respiratory signs using cervical radiography. Forty brachycephalic dogs without cardiopulmonary diseases were included. The nasopharyngeal luminal change was calculated on inspiratory and expiratory cervical lateral radiographs. The median nasopharyngeal luminal change was 21.6% (range, 0.3–85.6%). In five dogs, a nasopharyngeal luminal change of >50% was identified. There was no correlation between nasopharyngeal luminal changes and age, sex, body weight, or body condition score. These results suggest that brachycephalic dogs without cardiopulmonary diseases may be over-diagnosed with partial pharyngeal collapse. Further studies comparing nasopharyngeal luminal changes between clinically healthy brachycephalic dogs and dogs with respiratory signs are warranted.

著者

Funada Shin

出版者

電気通信大学

巻号頁・発行日

2022-12-16

---

2022

著者

Takaaki SATO Rena TAKAHASHI Shin ROZAN Saki UCHIYAMA Yuta BABA Martina VICHEVA Ayaka SATO Masaomi IKEDA Tomohiro TAKAGAKI Toru NIKAIDO Junji TAGAMI

出版者

The Japanese Society for Dental Materials and Devices

雑誌

Dental Materials Journal (ISSN:02874547)

巻号頁・発行日

vol.40, no.3, pp.719-726, 2021-05-25 (Released:2021-05-29)

参考文献数

34

被引用文献数

1 2

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This study evaluated the effect of temporary sealing materials and cleaning protocols on the bond strength of resin cement applied to dentin using resin-coating technique. Scotchbond Universal Adhesive and Filtek Supreme Ultra Flowable were applied to bovine dentin. Forty-five specimens were divided into the following three groups according to the temporary sealing materials: Cav-: CAVITON EX, Vas-: COCOA BUTTER and FIT SEAL, and Sep-: Washable SEP and FIT SEAL. Each material was placed on resin-coated dentin. After 1-week water storage, one of the following three cleaning protocols was performed: -WA: washed with water, -BR: brushed with PRESSAGE, and -AF: cleaned with AIR-FLOW. Microtensile bond strength test and EDS analysis were conducted. Irrespective of the cleaning protocol used, Washable SEP demonstrated less residual debris on resin-coated dentin, resulting in high bond strength. Regardless of the temporary sealing material applied, AIR-FLOW demonstrated less residual debris, resulting in high bond strength.

著者

Ken-ichi Okumura Kazuyuki Honki Shin-ya Ohba

出版者

The Japanese Society of Systematic Zoology

雑誌

Species Diversity (ISSN:13421670)

巻号頁・発行日

vol.24, no.2, pp.247-252, 2019-11-25 (Released:2019-11-25)

参考文献数

27

被引用文献数

2 1

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Iwogumoa songminjae (Paik and Yaginuma in Paik et al., 1969) is recorded for the first time from Japan on the basis of specimens collected in the Tsushima Islands, Kyushu and previously identified as I. insidiosa (L. Koch, 1878). The relationships among the Japanese species of Iwogumoa Kishida, 1955 are analyzed using mitochondrial cytochrome c oxidase subunit I with various Japanese species of Coelotes Blackwall, 1841 sensu lato as the outgroup. A new synonym is proposed through a comparison of morphological characteristics and the results of our molecular analysis: Coelotes iyoensis Nishikawa, 2009 (known only from the male) is a junior synonym of Coelotes mohrii Nishikawa, 2009 (known only from the female).

著者

Risako Morishita Miki Shimada Minami Nagao Shin Shimizu Noriyasu Kamei Mariko Takeda-Morishita

出版者

The Pharmaceutical Society of Japan

雑誌

Biological and Pharmaceutical Bulletin (ISSN:09186158)

巻号頁・発行日

vol.46, no.2, pp.343-347, 2023-02-01 (Released:2023-02-01)

参考文献数

14

被引用文献数

1

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Owing to their unique physicochemical properties and diverse biological effects, ultrafine bubbles (UFBs) have recently been expected to be utilized for industrial and biological purposes. Thus, this study investigated the biological safety of UFBs in water for living beings in drinking the water with a view to future use in health sciences. In this study, we used H2-filled UFBs (NanoGAS®) that can hold hydrogen in the aqueous phase for a long time. Mice were randomly assigned to one of three groups: those receiving NanoGAS® water, reverse osmosis water, or natural mineral water, and they ingested it ad libitum for one month or three months. As a result, subchronic drinking of NanoGAS® water does not affect either the common blood biochemical parameters or the health of the organs and mucosal membranes. Our results, for the first time, scientifically demonstrated the biological safety of H2-filled UFBs water for subchronic oral consumption.

著者

Masahito Katsuki Yasuhiko Matsumori Kenta Kashiwagi Shin Kawamura Akihito Koh

出版者

Societas Neurologica Japonica

雑誌

臨床神経学 (ISSN:0009918X)

巻号頁・発行日

pp.cn-001812, (Released:2023-01-31)

参考文献数

26

被引用文献数

1

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Objectives: Tension-type headache (TTH) is the most prevalent type of primary headache disorder. Its acute pharmacotherapy is acetaminophen or non-steroidal anti-inflammatory drugs based on the Japanese Clinical Practice Guideline for Headache Disorders 2021. With Japan’s aging population, however, the number of TTH patients with comorbidities that have been treated by analgesics is increasing. Under this context, it is sometimes difficult to select an acute pharmacotherapy for TTH. Kakkonto, Japanese traditional herbal kampo medicine, is empirically used for TTH. We hypothesized that kakkonto has efficacy for TTH with painful comorbidities. Materials and Methods: We prospectively collected 10 consecutive TTH patients who had already taken analgesics for comorbidities. We prescribed 2.5 g of kakkonto (TJ-1), and patients took it. A numerical rating scale for pain before and 2 hours after kakkonto intake was evaluated. Results: Eight women and 2 men were included. The mean age was 71.0 ± 13.4 years old. Four patients had lower back pain, 2 had lumbar spinal stenosis, 2 had knee pain, 1 had neck pain, and 1 had shoulder myofasciitis. Celecoxib was used for 4 patients, acetaminophen for 3, loxoprofen for 2, and a combination of tramadol and acetaminophen for 1, as routinely used analgesics. The median numerical rating scale statistically improved from the median of 4 to that of 0. There were no side effects of kakkonto. Conclusion: Kakkonto showed efficacy as an acute medication for TTH with comorbidities that have been treated by analgesic.

著者

Hideto SHIRASAWA Chisato NISHIYAMA Rika HIRANO Takashi KOYANAGI Shujiro OKUDA Hiroki TAKAGI Shin KURIHARA

出版者

BMFH Press

雑誌

Bioscience of Microbiota, Food and Health (ISSN:21863342)

巻号頁・発行日

vol.42, no.1, pp.24-33, 2023 (Released:2023-01-01)

参考文献数

58

被引用文献数

1

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It has been reported that the intake of polyamines contributes to the extension of healthy life span in animals. Fermented foods contain high concentrations of polyamines thought to be derived from fermentation bacteria. This suggests that bacteria that produce high levels of polyamines could be isolated from fermented foods and utilized as a source of polyamines for human nutrition. In this study, Staphylococcus epidermidis FB146 was isolated from miso, a Japanese fermented bean paste, and found to have a high concentration of putrescine in its culture supernatant (452 μM). We analyzed the presence of polyamines in the culture supernatants and cells of the type strains of 21 representative Staphylococcus species in addition to S. epidermidis FB146, and only S. epidermidis FB146 showed high putrescine productivity. Furthermore, whole-genome sequencing of S. epidermidis FB146 was performed, and the ornithine decarboxylase gene (odc), which is involved in putrescine synthesis, and the putrescine:ornithine antiporter gene (potE), which is thought to contribute to the release of putrescine into the culture supernatant, were present on plasmid DNA harbored by S. epidermidis FB146.

著者

Yuichi OI Yasuhito HIRAI Shotaro DOKI Yuh OHTAKI Daisuke HORI Christina-Sylvia ANDREA Shin-ichiro SASAHARA Tamaki SAITO Ichiyo MATSUZAKI

出版者

THE JAPAN SOCIETY FOR AERONAUTICAL AND SPACE SCIENCES

雑誌

TRANSACTIONS OF THE JAPAN SOCIETY FOR AERONAUTICAL AND SPACE SCIENCES, AEROSPACE TECHNOLOGY JAPAN (ISSN:18840485)

巻号頁・発行日

vol.16, no.6, pp.476-480, 2018 (Released:2018-09-04)

参考文献数

16

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NIRS measurement was carried out in a confinement experiment for the first time. A tendency for NIRS integrated values to decrease was observed. Problems such as the learning effect needed to be resolved. SOC had an upward trend. Regarding POMS, the first day of confinement showed the highest score, after which no obvious deterioration was seen.

著者

勝川 行雄 久保 雅仁 原 弘久 末松 芳法 石川 遼子 鹿野 良平 Quintero Noda Carlos 大場 崇義 石川 真之介 清水 敏文 阿南 徹 永田 伸一 一本 潔 Solanki Sami Del Toro Iniesta Jose Carlos SUNRISE-3 team Katsukawa Yukio Kubo Masahito Hara Hirohisa Suematsu Yoshinori Ishikawa Ryohko Kano Ryouhei Quintero Noda Carlos Oba Takayoshi Ishikawa Shin-nosuke Shimizu Toshifumi Anan Tetsu Nagata Shinichi Ichimoto Kiyoshi Solanki Sami Del Toro Iniesta Jose Carlos SUNRISE-3 team

出版者

宇宙航空研究開発機構宇宙科学研究所(JAXA)(ISAS)

雑誌

第17回宇宙科学シンポジウム 講演集 = Proceedings of the 17th Space Science Symposium

巻号頁・発行日

2017-01

---

第17回宇宙科学シンポジウム (2017年1月5日-6日. 宇宙航空研究開発機構宇宙科学研究所(JAXA)(ISAS)相模原キャンパス), 相模原市, 神奈川県

著者

Jung-Kyu Han Youngchul Shin Hyo-Soo Kim

出版者

The Japanese Circulation Society

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

vol.86, no.12, pp.1925-1933, 2022-11-25 (Released:2022-11-25)

参考文献数

84

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Advances in nuclear reprogramming technology have enabled the dedifferentiation and transdifferentiation of mammalian cells. Forced induction of the key transcription factors constituting a transcriptional network can convert cells back to their pluripotent status or directly to another cell fate without inducing pluripotency. To date, direct conversion to several cell types, including cardiomyocytes, various types of neurons, and pancreatic β-cells, has been reported. We previously demonstrated direct lineage reprogramming of adult fibroblasts into induced endothelial cells (iECs) in mice and humans. In contrast to induced pluripotent stem cells, for which there is consensus on the criteria defining pluripotency, such criteria have not yet been established in the field of direct conversion. We thus suggest that careful assessment of the status of converted cells using genetic and epigenetic profiling, various functional assays, and the use of multiple readouts is essential to determine successful conversion. As direct conversion does not go through pluripotent status, this technique can be utilized for therapeutic purposes without the risk of tumorigenesis. Further, direct conversion can be induced in vivo by gene delivery to the target tissue or organ in situ. Thus, direct conversion technology can be developed into cell therapy or gene therapy for regenerative purposes. Here, we review the potential and future directions of direct cell fate conversion and iECs.

著者

Naoki Doi Kazuichi Araki Yoichiro Fukuta Yudai Kuwagaito Yukinori Yamauchi Yasushi Sasai Shin-ichi Kondo Masayuki Kuzuya

出版者

Japanese Society for Food Science and Technology

雑誌

Food Science and Technology Research (ISSN:13446606)

巻号頁・発行日

pp.FSTR-D-22-00120, (Released:2023-01-06)

被引用文献数

2

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Glycation reactions between proteins and sugars or their metabolites produce advanced glycation end-products, and the glycation of collagen in normal human dermal fibroblasts (NHDF) causes skin spots and freckles. UV exposure induces oxidative stress in NHDF, which overexpresses enzymes that degrade collagen, resulting in dry skin and wrinkling. Herein, we produced a novel polyphenolic decoction of Chaga mushroom extracted with a fermentation medium. Chaga polyphenol decoction (CPD) inhibited the glycation of albumin and collagen gel 3 to 4 times more than 2-aminoguanidine. The antioxidant effects of CPD were investigated using the fluorescence of an intracellular reactive oxygen species (ROS) scavenger, and NHDF exposed to UV-A for 60 min (9.5 J/cm2) after pre-treatment with 190 µg/mL of CPD suppressed ROS scavenger emission by 50 % compared to treatment with phosphate buffer saline. These results suggest that CPD might be a promising glycation inhibitor and ROS scavenger.

著者

Jinju Park Han Joo Kim Sang Hwa Shin Eunjung Park Jin-Kyoung Oh Eun Young Park Min Kyung Lim

出版者

Japan Epidemiological Association

雑誌

Journal of Epidemiology (ISSN:09175040)

巻号頁・発行日

vol.32, no.8, pp.357-362, 2022-08-05 (Released:2022-08-05)

参考文献数

22

被引用文献数

3 9

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Background: The popularity of heated tobacco products (HTPs) has been growing globally but, limited information exists on tobacco use behaviors and its impact on tobacco control. This study investigates awareness and perception of HTPs among tobacco users and whether perceptions of HTPs are associated with HTP use and intention to quit.Methods: We invited 2,000 tobacco users aged 19–65 years with countrywide representation to an online survey in November 2018. Information on general characteristics, tobacco use behaviors, awareness and perception of HTPs, and intention to quit were gathered. Multinomial logistic regression analysis and ANCOVA were used for estimation of association and comparison.Results: Among all tobacco users, 36.8% were classified as ever users, whereas 28.3% had used HTPs in the past 30 days, which was higher than expected. Users of liquid-based e-cigarettes (odds ratio [OR] 1.578; 95% confidence interval [CI], 1.210–2.056) and poly-product users (OR 2.029; 95% CI, 1.121–3.671) showed higher intention to quit within 1 month when compared to users of conventional cigarettes (CCs), whereas HTP users and dual product users did not. HTP users rated HTPs more favorably than CCs in terms of smoke, smell, harm, aid in quitting, design, and price than users of other products did (P-value < 0.001).Conclusion: We find that positive perception of HTPs following strategic marketing from tobacco companies could have contributed to a greater increase in HTP use than expected in Korea. However, HTPs might not be considered substitutes for CCs for quitting tobacco use because a significant proportion of dual product users reported a lower intention to quit.